Annotation Detail

Information
Associated Genes
TLR9
Associated Variants
TLR9 MUTATION
TLR9 MUTATION
Associated Disease
Solid tumour
Source Database
DisGeNET
Description
Preclinical and clinical studies of MGN1703 have confirmed that this TLR-9 agonist has therapeutic potential in a variety of solid tumors, while long-term treatment with high doses was very well tolerated.
Pubmed
25577571
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
5
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs