Annotation Detail
Information
- Associated Genes
- TLR9
- Associated Variants
-
TLR9 MUTATION
TLR9 MUTATION - Associated Disease
- Prostatic Neoplasms
- Source Database
- DisGeNET
- Description
- A series of preclinical studies have demonstrated the superiority of the Ad/PSA vaccine to other PSA vaccines for the induction of anti-PSA immune responses, the ability of Ad/PSA vaccination combined with cytokine gene therapy and the TLR9 agonist CpG to enhance the anti-prostate tumor immunotherapy, and the reduction of negative regulatory elements when the vaccine was combined with 5-fluoruracil administration.
- Pubmed
- 24847764
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 2
- Original source reporting the Gene Disease association
- BeFree,LHGDN
- DisGENET score for the Gene Disease association
- 0.00299579211454747
Drugs