Annotation Detail

Information
Associated Genes
TLR9
Associated Variants
TLR9 MUTATION
TLR9 MUTATION
Associated Disease
Autoimmune Diseases
Source Database
DisGeNET
Description
In the past, most studies focused on the intracellular TLRs, such as TLR3, TLR7, and TLR9, but recent studies reveal that cell surface TLRs, especially TLR2 and TLR4, also play an essential role in the development of autoimmune diseases and afford multiple therapeutic targets.
Pubmed
24352680
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
9
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00217153497664243
Drugs