Annotation Detail
Information
- Associated Genes
- TLR9
- Associated Variants
-
TLR9 MUTATION
TLR9 MUTATION - Associated Disease
- Lupus Erythematosus, Systemic
- Source Database
- DisGeNET
- Description
- In summary, G-modification of INH-ODNs improved their ability to impair TLR7- and TLR9-mediated signaling in those human immune cells which are considered as crucial in the pathophysiology of SLE.
- Pubmed
- 25695778
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 10
- Original source reporting the Gene Disease association
- BeFree,GAD,LHGDN
- DisGENET score for the Gene Disease association
- 0.0258603796743394
Drugs