Annotation Detail

Information
Associated Genes
TLR9
Associated Variants
TLR9 MUTATION
TLR9 MUTATION
Associated Disease
Malignant neoplasm of stomach
Source Database
DisGeNET
Description
For TLR9 -1486 T/C, multiple logistic regression analyses revealed that compared with the TT homozygote, patients with both the TC variant (adjusted odds ratio (OR) = 1.47, 95% confidence interval (CI) = 1.04-2.10) and the CC variant (adjusted OR = 1.63, 95% CI = 1.01-2.64) had higher risks of gastric cancer.
Pubmed
23776537
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00081432561624091
Year of publication
2013
Drugs