meningococcal meningitis
Information
- Disease name
- meningococcal meningitis
- Disease ID
- DOID:0080176
- Description
- "A bacterial meningitis that has_material_basis_in Neisseria meningitidis infection." [url:http\://www.who.int/mediacentre/factsheets/fs141/en/, url:https\://en.wikipedia.org/wiki/Meningococcal_disease, url:https\://www.cdc.gov/meningococcal/about/symptoms.html]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT00944034 | Completed | Phase 2/Phase 3 | Safety, Tolerability and Immunogenicity of Meningococcal B Recombinant Vaccine Administered as Booster Dose at 12, 18 or 24 Months of Age in Toddlers (12-24 Months) Primed With a Three-Dose Immunization Series as Infants in Study V72P12 | July 2009 | January 2012 |
| NCT00310856 | Completed | Phase 2 | Immunogenicity and Safety of MenACWY in Infants (6 & 12 Months) | June 2005 | November 2006 |
| NCT00329901 | Completed | Phase 3 | Immunogenicity and Safety of the Concomitant Administration of a Tdap Vaccine and Meningococcal ACWY Conjugate Vaccine in Healthy Subjects Aged 11-25 Years | April 2006 | December 2007 |
| NCT00355121 | Completed | Phase 2 | Study of Menactra® in Children Aged 4 to 6 Years When Administered Concomitantly With a Fifth Dose of DAPTACEL® | October 2006 | July 2009 |
| NCT00384397 | Completed | Phase 3 | A Study of 2 Doses of Menactra®, a Meningococcal Conjugate Vaccine in Healthy Toddlers | September 2006 | February 2009 |
| NCT00422292 | Completed | Phase 3 | Immunogenicity and Safety of Pediatric Vaccines When Administered With Menactra® in Healthy Toddlers | December 2006 | April 2009 |
| NCT00450437 | Completed | Phase 3 | A Study to Evaluate Safety and Immune Response of Novartis Meningococcal ACWY Conjugate Vaccine In US Adolescents and Adults | March 2007 | January 2008 |
| NCT00474487 | Completed | Phase 3 | A Study to Evaluate Safety and Immune Response of Novartis Meningococcal ACWY Vaccine In Healthy Adults | May 2007 | February 2008 |
| NCT00483574 | Completed | Phase 3 | Study of the Safety of Menactra® Vaccine When Administered With Other Pediatric Vaccines to Healthy Toddlers | May 2007 | April 2009 |
| NCT00518180 | Completed | Phase 3 | A Study to Evaluate Safety and Immune Response of Novartis Meningococcal ACWY Conjugate Vaccine In Adolescents | July 2007 | October 2008 |
| NCT00667602 | Completed | Phase 3 | Safety and Immunogenicity Evaluation After One or Two Doses of Novartis Meningococcal ACWY Conjugate Vaccine in Healthy Infants and Toddlers | March 2008 | October 2010 |
| NCT00856297 | Completed | Phase 3 | Evaluation of Persistence of Anti-meningococcal Bactericidal Antibodies Among Adolescents Who Previously Received MenACWY Conjugate Vaccine | February 2009 | November 2012 |
| NCT00874549 | Completed | Phase 1/Phase 2 | Exploratory Trial to Evaluate the Safety and Immunogenicity of Menactra® and Menomune® Vaccines in Subjects ≥ 56 Years | October 2007 | October 2008 |
| NCT00937521 | Completed | Phase 2 | Safety and Immunogenicity in Dose-Ranging and Formulation-Finding Meningococcal B (MenB) Vaccine Study in 2-month-old Infants | July 2009 | February 2012 |
| NCT00310817 | Completed | Phase 2 | Safety and Immunogenicity of Novartis Meningococcal ACWY Conjugate Vaccine in Healthy Children Aged 12-59 Months. | March 2005 | May 2006 |
| NCT00994695 | Completed | Phase 2 | Safety, Immunogenicity and Reactogenicity Trial of Mencevax ACW135 Vaccine | November 2005 | November 2007 |
| NCT01018732 | Completed | Phase 2 | A Study to Evaluate the Persistence and Immune Response to a Booster Dose of MenACWY | January 2010 | July 2010 |
| NCT01148017 | Completed | Phase 3 | Evaluation of Meningococcal Immune Response Among Children Who Previously Received MenACWY Conjugate Vaccine | July 2010 | April 2013 |
| NCT01148524 | Completed | Phase 2/Phase 3 | Assessment of Antibody Persistence at Eighteen Months After the Completion of the Vaccination Course in Study V72P10 | August 2010 | January 2012 |
| NCT01192997 | Completed | Phase 2/Phase 3 | Comparison of Two Meningococcal ACWY Conjugate Vaccines | June 2012 | March 2014 |
| NCT01210885 | Completed | Phase 2 | Immunogenicity and Safety of Different rMenB Plus MenACWY Formulations in Adolescents | December 2010 | July 2011 |
| NCT01214837 | Completed | Phase 3 | Safety and Immunogenicity of 2 or 3 Doses of MenACWY Conjugate Vaccine in Healthy Infants and the Effects of a Booster Dose of MenACWY Administered in the Second Year of Life | October 2010 | May 2012 |
| NCT01239043 | Completed | Phase 2 | Antibody Persistence and Response to Re-vaccination With Either Menactra® or Menomune® 3 Years After Initial Vaccination | November 2010 | February 2012 |
| NCT01274897 | Completed | Phase 3 | A Multi-center, Observer-blind, Placebo-controlled, Randomized Study to Evaluate the Immunogenicity and Safety of MenACWY in Adolescents and Adults in Korea | December 2010 | March 2011 |
| NCT01339923 | Completed | Phase 3 | A Phase 3B, Open Label, Multi-Center Study to Evaluate the Safety, Tolerability and Immunogenicity of Novartis Meningococcal B Recombinant Vaccine When Administered Alone to Healthy Infants According to Different Immunization Schedules and to Healthy Children Aged 2 to 10 Years | April 2011 | December 2014 |
| NCT01367158 | Completed | Phase 2 | Safety, Tolerability and Immunogenicity of a Third Dose of One of Four Different Formulations of rMenB + MenACWY Combination Vaccine in Adolescents Who Previously Received the Same Study Vaccines | July 2011 | July 2012 |
| NCT01423084 | Completed | Phase 3 | Safety and Immunogenicity of Novartis Meningococcal B Vaccine Formulated With OMV Manufactured at Two Different Sites, in Healthy Adolescents Aged 11-17 Years | August 2011 | December 2011 |
| NCT01424644 | Completed | Phase 4 | A Phase 4, Placebo-Controlled, Randomized Study to Evaluate the Immunogenicity and Safety of HPV and Tdap When Administered With MenACWY in Adolescents | September 2011 | December 2012 |
| NCT01434680 | Completed | Phase 2 | Evaluating the Comparative Safety and Immunogenicity of Three Lots of Novartis Meningococcal C Conjugate Vaccine in Healthy Toddlers | September 2011 | November 2012 |
| NCT01453348 | Completed | Phase 3 | Study to Evaluate the Safety and Immunogenicity of Combined Hepatitis A/B Vaccine With MenACWY-CRM Conjugate Vaccine | October 2011 | January 2012 |
| NCT01466387 | Completed | Phase 3 | A Phase 3b, Randomized, Open-Label Study to Evaluate the Safety and Immunogenicity of Select Travel Vaccines When Administered Concomitantly With MenACWY in Adults | November 2011 | April 2012 |
| NCT01478347 | Completed | Phase 3 | A Phase 3b Study to Assess the Safety of Novartis Meningococcal B Recombinant Vaccine When Administered in Healthy At-risk Adults | May 2013 | November 2014 |
| NCT01482052 | Completed | Phase 1 | Safety Study of Group A, C, Y & W-135 Meningococcal Polysaccharide Diphtheria Toxoid Conjugate Vaccine for Meningitis | November 2011 | January 2013 |
| NCT01519713 | Completed | Phase 3 | Study of a Single Dose of Meningococcal Polysaccharide Diphtheria Toxoid Conjugate Vaccine (SP284) in Japanese Subjects | January 2012 | December 2012 |
| NCT01717638 | Completed | Phase 3 | Persistence of Antibody Levels and Response to Fifth or Third Meningococcal B Recombinant Vaccine in 4-year Old Healthy Children Who Previously Participated in Study V72P12E1 | November 2012 | October 2013 |
| NCT01732627 | Completed | Phase 2 | Study of a Quadrivalent Meningococcal Conjugate Vaccine in Subjects Aged 56 and Older | November 12, 2012 | January 17, 2013 |
| NCT01894919 | Completed | Phase 3 | Antibody Persistence, and Safety and Tolerability of a Booster Dose of the Meningococcal B Vaccine After the Completion of the Vaccination Course in Study V72_28 | June 2013 | November 2015 |
| NCT01897402 | Completed | Phase 2 | Immunogenicity and Safety of Group A, C, Y & W-135 Meningococcal Polysaccharide Diphtheria Toxoid Conjugate Vaccine | July 2013 | December 2014 |
| NCT02199691 | Completed | Phase 2 | Immunogenicity and Safety of an Investigational Quadrivalent Meningococcal Conjugate Vaccine in Healthy Adolescents | July 22, 2014 | October 2, 2015 |
| NCT02864927 | Completed | Phase 4 | Postmarketing Surveillance Study for Use of Menactra® in the Republic of Korea | July 21, 2016 | June 12, 2019 |
| NCT02955797 | Completed | Phase 3 | Immunogenicity and Safety of an Investigational Quadrivalent Meningococcal Conjugate Vaccine in Toddlers | February 24, 2017 | October 26, 2017 |
| NCT03077438 | Completed | Phase 3 | Study of an Investigational Quadrivalent Meningococcal Conjugate Vaccine Administered in Children Aged 2 to 9 Years | February 17, 2017 | October 10, 2017 |
| NCT03205358 | Completed | Phase 2 | Immunogenicity and Safety of an Investigational Quadrivalent Meningococcal Conjugate Vaccine in Healthy Toddlers | March 31, 2015 | August 19, 2015 |
| NCT03964012 | Completed | Phase 3 | Study to Assess Immunegnicity & Safety of Pentavalent Meningococcal Vaccine (NmCV-5) | August 20, 2019 | March 4, 2021 |
| NCT02500511 | Completed | Persistence of Protective Antibody Titers 12-24 Months After NmVac4-A/C/Y/W-135-DT Vaccination: Follow Up Study | June 2015 | September 2015 | |
| NCT02591290 | Completed | Phase 4 | Immunogenicity and Safety of Two-Dose Series of Menactra® in Japanese Healthy Adult Subjects | October 20, 2015 | March 16, 2016 |
| NCT02633787 | Completed | Phase 4 | Persistence of Bactericidal Antibodies in Adults Who Received a Booster Dose of Menactra® Approximately 4 Years Earlier | December 2015 | March 2016 |
| NCT02640404 | Completed | Phase 2 | Safety of a Meningococcal (Groups A, C, Y and W-135) Polysaccharide Diphtheria Toxoid Conjugate Vaccine in Healthy Subjects in Vietnam | June 6, 2016 | December 5, 2016 |
| NCT02699840 | Completed | Observational Safety Study of Menactra® Administered Under Standard Health Care Practice in the Russian Federation | February 2016 | July 25, 2016 | |
| NCT02752906 | Completed | Phase 3 | Immunogenicity and Safety of a Booster Dose of an Investigational Quadrivalent Meningococcal Conjugate Vaccine | April 15, 2016 | December 19, 2016 |
| NCT02842853 | Completed | Phase 3 | Immune Lot Consistency, Immunogenicity, and Safety of an Investigational Quadrivalent Meningococcal Conjugate Vaccine | July 15, 2016 | February 28, 2017 |
| NCT02842866 | Completed | Phase 3 | Immunogenicity and Safety of an Investigational Quadrivalent Meningococcal Conjugate Vaccine in Adults 56 Years and Older | July 15, 2016 | February 13, 2017 |
| NCT06226714 | Not yet recruiting | Phase 3 | A Clinical Trial of ACYW135 Group Meningococcal Polysaccharide Conjugate Vaccine (CRM197 Vector) in 18-59 Year Olds | March 2024 | October 2024 |
| NCT06337071 | Not yet recruiting | Phase 2 | A Study of the ACYW135 Meningococcal Polysaccharide Conjugate Vaccine | March 20, 2024 | June 2025 |
| NCT06131554 | Recruiting | Phase 3 | A Clinical Trial to Evaluate the Immunogenicity and Safety of Group ACYW135 Meningococcal Conjugate Vaccine (CRM197) in Adults Aged 18 to 55 Years | March 20, 2024 | December 2024 |
| NCT02481232 | Unknown status | Phase 1 | A Single-center, Open Trials to Evaluate the Safety of Freeze-dried Group ACYW135 Meningococcal Conjugate Vaccine | June 2015 | June 2016 |
| NCT02919293 | Unknown status | Phase 1/Phase 2 | Immunogenicity and Safety of Meningococcal Groups A and C and Haemophilus b Conjugate Vaccine in Infants 2 to 5 Months of Age | August 2016 | May 2017 |
- Disase is a (Disease Ontology)
- DOID:9470
- Cross Reference ID (Disease Ontology)
- ICD10CM:A39.0
- Cross Reference ID (Disease Ontology)
- ICD9CM:036.0
- Cross Reference ID (Disease Ontology)
- MESH:D008585
- OrphaNumber from OrphaNet (Orphanet)
- 33475