chr17:58269855:> Detail (hg38)
Information
Genome
Assembly | Position |
---|---|
hg19 | chr17:56,347,216-56,358,296 |
hg38 | chr17:58,269,855-58,280,935 |
HGVS
Type | Transcript | Protein |
---|---|---|
Summary
MGeND
Clinical significance | |
Variant entry | |
GWAS entry | |
Disease area statistics | Show details |
Frequency
[No Data.]
Prediction
[No Data.]
ClinVar
Clinical Significance | |
Review star | [No Data.] |
Show details |
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
Score | Disease name | Description | Source | Pubmed | Links |
---|---|---|---|---|---|
0.005 | squamous cell carcinoma | NA | BeFree,GAD | Detail | |
0.005 | Carotid Artery Diseases | NA | GAD,LHGDN | Detail | |
0.002 | cerebral infarction | NA | GAD | Detail | |
0.120 | brain ischemia | NA | CTD_human | Detail | |
<0.001 | Malignant tumor of cervix | Association of myeloperoxidase polymorphism (G463A) with cervix cancer. | BeFree | 25701357 | Detail |
0.002 | Charcot-Marie-Tooth disease | NA | GAD | Detail | |
0.002 | Congenital chromosomal disease | NA | BeFree | Detail | |
0.080 | Bronchitis, Chronic | NA | RGD | Detail | |
0.001 | Churg-Strauss syndrome | NA | BeFree | Detail | |
0.123 | colitis | The present study demonstrated that R1 alleviated the severity of dextran sulfat... | BeFree,CTD_human | 25472953 | Detail |
0.123 | colitis | TNBS induced colitis in the rats was confirmed with weight loss (13.7 ± 3.2 g) a... | BeFree,CTD_human | 25574088 | Detail |
0.121 | ulcerative colitis | NA | BeFree,CTD_human | Detail | |
<0.001 | colorectal carcinoma | NA | BeFree | Detail | |
<0.001 | Colorectal Neoplasms | NA | BeFree | Detail | |
0.002 | Coronary Arteriosclerosis | Meta-analysis of myeloperoxidase gene polymorphism and coronary artery disease s... | BeFree | 24748187 | Detail |
0.003 | cystic fibrosis | NA | BeFree,LHGDN | Detail | |
0.080 | cystitis | NA | RGD | Detail | |
<0.001 | Mental Depression | Myeloperoxidase gene expression and cognitive functions in depression. | BeFree | 25038328 | Detail |
<0.001 | depressive disorder | Myeloperoxidase gene expression and cognitive functions in depression. | BeFree | 25038328 | Detail |
0.120 | Drug Eruptions | NA | CTD_human | Detail | |
0.003 | diabetes mellitus | NA | BeFree,LHGDN | Detail | |
0.200 | Diabetes Mellitus, Experimental | NA | CTD_human,RGD | Detail | |
0.005 | Diabetes Mellitus, Non-Insulin-Dependent | An association between MPO -463 G/A polymorphism and type 2 diabetes. | BeFree,GAD | 25056433 | Detail |
0.003 | Diabetic Angiopathies | NA | LHGDN | Detail | |
0.006 | Diabetic Nephropathy | NA | BeFree,LHGDN | Detail | |
<0.001 | diarrhea | NA | BeFree | Detail | |
0.002 | DNA Damage | NA | GAD | Detail | |
0.005 | duodenal ulcer | NA | BeFree,GAD,LHGDN | Detail | |
<0.001 | Shigella Infections | NA | BeFree | Detail | |
0.002 | Pathological accumulation of air in tissues | NA | GAD | Detail | |
<0.001 | endometriosis | NA | BeFree | Detail | |
0.080 | Enteritis | NA | RGD | Detail | |
0.007 | Esophageal Neoplasms | NA | BeFree,GAD | Detail | |
<0.001 | Exanthema | NA | BeFree | Detail | |
0.002 | Disorder of eye | NA | GAD | Detail | |
0.005 | gastritis | NA | BeFree,GAD | Detail | |
<0.001 | Gastritis, Atrophic | NA | BeFree | Detail | |
<0.001 | Gingival Diseases | NA | BeFree | Detail | |
0.004 | glomerulonephritis | NA | BeFree,LHGDN | Detail | |
0.002 | Graft-vs-Host Disease | NA | GAD | Detail | |
<0.001 | chronic granulomatous disease | NA | BeFree | Detail | |
0.002 | Hay fever | NA | GAD | Detail | |
0.005 | Head and Neck Neoplasms | NA | GAD | Detail | |
<0.001 | cardiac arrest | NA | BeFree | Detail | |
<0.001 | Heart failure | NA | BeFree | Detail | |
<0.001 | congestive heart failure | NA | BeFree | Detail | |
<0.001 | Hematological Disease | NA | BeFree | Detail | |
0.003 | hemochromatosis | NA | LHGDN | Detail | |
0.003 | hepatitis C | Myeloperoxidase gene polymorphism predicts fibrosis severity in women with hepat... | BeFree,GAD | 24882572 | Detail |
0.003 | Hypercholesterolemia, Familial | NA | LHGDN | Detail | |
<0.001 | Hyperdistention | LPS plus hyperinflation (double-hit) increased all ALI parameters (ELW, EVPE, pe... | BeFree | 25097454 | Detail |
0.002 | Hypersensitivity | NA | GAD | Detail | |
0.002 | Immediate hypersensitivity | NA | GAD | Detail | |
<0.001 | Hypertensive disease | NA | BeFree | Detail | |
0.080 | Hypertension, Renovascular | NA | RGD | Detail | |
<0.001 | Immunologic Deficiency Syndromes | NA | BeFree | Detail | |
0.133 | Inflammation | NA | CTD_human,GAD,LHGDN | Detail | |
<0.001 | Inflammatory Bowel Diseases | NA | BeFree | Detail | |
<0.001 | influenza | NA | BeFree | Detail | |
0.006 | ischemia | NA | BeFree,GAD,LHGDN | Detail | |
0.120 | keratosis | NA | CTD_human | Detail | |
0.124 | Kidney Diseases | NA | BeFree,CTD_human,GAD | Detail | |
<0.001 | Kidney Failure, Acute | NA | BeFree | Detail | |
0.009 | Kidney Failure, Chronic | NA | BeFree,GAD,LHGDN | Detail | |
0.005 | Laryngeal neoplasm | NA | GAD | Detail | |
0.003 | Fibroid Tumor | NA | BeFree,GAD | Detail | |
0.018 | leukemia | In conclusion, we here demonstrate, exemplarily for MPO, that leukemia-derived H... | BeFree,GAD,LHGDN | 24736212 | Detail |
<0.001 | chronic lymphocytic leukemia | NA | BeFree | Detail | |
0.002 | lymphoid leukemia | NA | BeFree | Detail | |
0.005 | Acute lymphocytic leukemia | NA | BeFree | Detail | |
<0.001 | Leukemia, Lymphocytic, Acute, L1 | NA | BeFree | Detail | |
<0.001 | Acute Megakaryocytic Leukemias | NA | BeFree | Detail | |
<0.001 | acute biphenotypic leukemia | NA | BeFree | Detail | |
0.017 | Leukemia, Myelocytic, Acute | NA | BeFree,GAD,LHGDN | Detail | |
0.003 | myeloid leukemia | NA | BeFree | Detail | |
0.001 | Myeloid Leukemia, Chronic | NA | BeFree | Detail | |
<0.001 | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma | NA | BeFree | Detail | |
0.004 | acute promyelocytic leukemia | NA | BeFree | Detail | |
<0.001 | liver cirrhosis | NA | BeFree | Detail | |
0.123 | Liver Cirrhosis, Alcoholic | NA | BeFree,CTD_human,GAD | Detail | |
0.002 | Liver diseases | NA | GAD | Detail | |
0.002 | Liver neoplasms | NA | GAD | Detail | |
0.124 | Lung diseases | NA | BeFree,CTD_human,LHGDN | Detail | |
0.083 | Chronic Obstructive Airway Disease | NA | BeFree,GAD,RGD | Detail | |
0.141 | Lung Neoplasms | NA | CTD_human,GAD,LHGDN | Detail | |
<0.001 | Lupus Vulgaris | NA | BeFree | Detail | |
<0.001 | Lupus Erythematosus, Discoid | NA | BeFree | Detail | |
0.003 | Lupus Erythematosus, Systemic | NA | BeFree,GAD | Detail | |
0.003 | lupus nephritis | NA | BeFree,LHGDN | Detail | |
0.003 | lymphoma | NA | BeFree,GAD | Detail | |
0.009 | Lymphoma, Non-Hodgkin | NA | GAD | Detail | |
0.003 | Malignant neoplasm of stomach | NA | BeFree,GAD | Detail | |
<0.001 | Monosomy | NA | BeFree | Detail | |
0.009 | Mouth Neoplasms | NA | GAD | Detail | |
0.003 | multiple myeloma | NA | BeFree,GAD | Detail | |
0.010 | multiple sclerosis | NA | BeFree,GAD,LHGDN | Detail | |
0.011 | myocardial infarction | NA | BeFree,GAD,LHGDN | Detail | |
0.002 | narcolepsy | NA | GAD | Detail | |
<0.001 | Neoplasm Metastasis | NA | BeFree | Detail | |
0.002 | Neoplasm Recurrence, Local | NA | GAD | Detail | |
<0.001 | nephritis | NA | BeFree | Detail | |
0.003 | nephrosclerosis | NA | LHGDN | Detail | |
<0.001 | Spots on skin | Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transfera... | BeFree | 14716779 | Detail |
<0.001 | Exanthema | Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transfera... | BeFree | 14716779 | Detail |
0.001 | obesity | Validation of the gene expression levels of ELANE (neutrophil elastase) and MPO ... | BeFree | 25388404 | Detail |
0.125 | Occupational Diseases | NA | CTD_human,GAD | Detail | |
0.002 | Oropharyngeal Neoplasms | NA | GAD | Detail | |
<0.001 | ovarian carcinoma | NA | BeFree | Detail | |
0.125 | Cardiovascular Diseases | We enrolled 1977 Japanese type 2 diabetic subjects without history of CVD (males... | BeFree | 24933031 | Detail |
0.005 | Pancreatic Neoplasm | NA | GAD,LHGDN | Detail | |
0.120 | pancreatitis | NA | CTD_human | Detail | |
0.005 | Coronary heart disease | We enrolled 1977 Japanese type 2 diabetic subjects without history of CVD (males... | BeFree | 24933031 | Detail |
<0.001 | Parkinson disease | Effect of the myeloperoxidase inhibitor AZD3241 on microglia: a PET study in Par... | BeFree | 26137956 | Detail |
0.002 | Peptic Ulcer | NA | GAD | Detail | |
0.003 | Periodontal Diseases | NA | BeFree,GAD | Detail | |
0.003 | Periodontitis, Juvenile | NA | BeFree,GAD | Detail | |
0.005 | Pharyngeal Neoplasms | NA | GAD | Detail | |
0.005 | pneumonia | NA | BeFree,GAD | Detail | |
0.002 | polymyalgia rheumatica | NA | GAD | Detail | |
0.123 | Precancerous Conditions | NA | BeFree,CTD_human,GAD | Detail | |
<0.001 | Preleukemia | NA | BeFree | Detail | |
0.123 | Prostatic Neoplasms | NA | CTD_human,LHGDN | Detail | |
0.001 | pulmonary edema | NA | BeFree | Detail | |
0.001 | kidney failure | NA | BeFree | Detail | |
0.200 | Reperfusion Injury | NA | CTD_human,RGD | Detail | |
0.005 | Respiratory Tract Diseases | NA | GAD | Detail | |
<0.001 | rosacea | NA | BeFree | Detail | |
<0.001 | Septicemia | NA | BeFree | Detail | |
0.120 | Shock, Hemorrhagic | NA | CTD_human | Detail | |
<0.001 | Shy-Drager Syndrome | NA | BeFree | Detail | |
0.005 | Stomach Diseases | NA | GAD | Detail | |
0.007 | Stomach Neoplasms | NA | GAD,LHGDN | Detail | |
<0.001 | Cerebrovascular accident | NA | BeFree | Detail | |
<0.001 | Subarachnoid Hemorrhage | Incidence of aneurysms and subarachnoid hemorrhage was significantly lower in my... | BeFree | 25922506 | Detail |
0.003 | Giant Cell Arteritis | NA | BeFree,GAD | Detail | |
0.120 | Infection by Trichuris trichiura | NA | CTD_human | Detail | |
<0.001 | Trisomy | NA | BeFree | Detail | |
<0.001 | tuberculosis | NA | BeFree | Detail | |
<0.001 | Unipolar Depression | NA | BeFree | Detail | |
0.120 | urticaria | NA | CTD_human | Detail | |
0.002 | Uterine Neoplasms | NA | GAD | Detail | |
0.006 | Vascular Diseases | NA | BeFree,GAD,LHGDN | Detail | |
0.014 | vasculitis | Proteinase 3 (PR3) and myeloperoxidase (MPO) are two major autoantigens in patie... | BeFree,LHGDN | 25060059 | Detail |
0.014 | vasculitis | Autoantigen excision, a novel method to detect autoantibody epitopes using mass ... | BeFree,LHGDN | 26033562 | Detail |
<0.001 | Virus Diseases | NA | BeFree | Detail | |
0.003 | vitiligo | NA | BeFree,GAD | Detail | |
0.005 | Helicobacter Infections | NA | GAD | Detail | |
<0.001 | B-Cell Lymphomas | NA | BeFree | Detail | |
<0.001 | Peripheral Vascular Diseases | NA | BeFree | Detail | |
<0.001 | Polyendocrinopathies, Autoimmune | NA | BeFree | Detail | |
0.006 | acute leukemia | NA | BeFree | Detail | |
0.003 | Squamous cell carcinoma of lung | NA | BeFree,GAD | Detail | |
<0.001 | Small cell carcinoma of lung | NA | BeFree | Detail | |
<0.001 | Myocardial Ischemia | NA | BeFree | Detail | |
<0.001 | Adenocarcinoma of lung (disorder) | NA | BeFree | Detail | |
<0.001 | esophageal carcinoma | NA | BeFree | Detail | |
<0.001 | Granulocytic Sarcoma | NA | BeFree | Detail | |
<0.001 | Lichen Planus, Oral | Association of single nucleotide polymorphisms in MPO and COX genes with oral li... | BeFree | 25823564 | Detail |
0.003 | hepatoblastoma | NA | BeFree,LHGDN | Detail | |
<0.001 | Adult Acute Myeloblastic Leukemia | NA | BeFree | Detail | |
<0.001 | pediatric acute myeloblastic leukemia | NA | BeFree | Detail | |
<0.001 | rapidly progressive glomerulonephritis | NA | BeFree | Detail | |
<0.001 | alpha 1-antitrypsin deficiency | NA | BeFree | Detail | |
0.002 | Mental deterioration | NA | GAD | Detail | |
<0.001 | Cerebral atrophy | NA | BeFree | Detail | |
<0.001 | pancreatic carcinoma | NA | BeFree | Detail | |
0.002 | Substance-Related Disorders | NA | GAD | Detail | |
<0.001 | pelvic inflammatory disease | NA | BeFree | Detail | |
0.078 | Malignant neoplasm of lung | HapMap-based study on the association between MPO and GSTP1 gene polymorphisms a... | BeFree,GAD | 24786234 | Detail |
0.003 | Sepsis | NA | BeFree,GAD | Detail | |
<0.001 | Renal sclerosis with hypertension | NA | BeFree | Detail | |
<0.001 | Mirror hands | NA | BeFree | Detail | |
0.003 | Chronic Periodontitis | NA | BeFree,GAD | Detail | |
<0.001 | Necrotizing glomerulonephritis | NA | BeFree | Detail | |
<0.001 | Carcinoma breast stage IV | NA | BeFree | Detail | |
<0.001 | Liver and Intrahepatic Biliary Tract Carcinoma | NA | BeFree | Detail | |
<0.001 | Acute Undifferentiated Leukemia | NA | BeFree | Detail | |
<0.001 | stage, ovarian epithelial cancer | NA | BeFree | Detail | |
<0.001 | Adenocarcinoma of pancreas | NA | BeFree | Detail | |
<0.001 | cervix carcinoma | Association of myeloperoxidase polymorphism (G463A) with cervix cancer. | BeFree | 25701357 | Detail |
0.001 | Senile Plaques | NA | BeFree | Detail | |
0.003 | Atrophic | NA | LHGDN | Detail | |
0.003 | Impaired cognition | NA | BeFree,GAD | Detail | |
<0.001 | Stable angina | The MPO -463 G/A polymorphism in the stable angina pectoris subgroup was evaluat... | BeFree | 24748187 | Detail |
0.005 | Complications of Diabetes Mellitus | NA | GAD,LHGDN | Detail | |
0.003 | Microscopic Polyangiitis | NA | BeFree | Detail | |
0.003 | Malignant neoplasm of liver | NA | BeFree,GAD | Detail | |
<0.001 | Malignant neoplasm of pancreas | NA | BeFree | Detail | |
<0.001 | Ischemic cardiomyopathy | NA | BeFree | Detail | |
<0.001 | Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site | NA | BeFree | Detail | |
0.004 | Malignant neoplasm of prostate | NA | BeFree,GAD | Detail | |
0.002 | Hematologic Neoplasms | NA | GAD | Detail | |
<0.001 | Hereditary hemochromatosis | NA | BeFree | Detail | |
<0.001 | multiple system atrophy | NA | BeFree | Detail | |
<0.001 | Specific granule deficiency | NA | BeFree | Detail | |
<0.001 | Idiopathic crescentic glomerulonephritis | NA | BeFree | Detail | |
<0.001 | lupus erythematosus | NA | BeFree | Detail | |
<0.001 | Overweight | NA | BeFree | Detail | |
<0.001 | Granulomatosis | NA | BeFree | Detail | |
0.001 | Acute myeloid leukemia, minimal differentiation | NA | BeFree | Detail | |
<0.001 | Metabolic syndrome X | After multivariate analysis adjustment, the GG genotype of MPO and the presence ... | BeFree | 24882572 | Detail |
<0.001 | Metabolic syndrome X | Investigation of genetic variation in MAPK11 and MAPK14 genes using additive gen... | BeFree | 25164947 | Detail |
<0.001 | Metabolic syndrome X | Relation of myeloperoxidase-463G/A polymorphism with metabolic syndrome and its ... | BeFree | 25482861 | Detail |
<0.001 | Neurodegenerative Disorders | NA | BeFree | Detail | |
<0.001 | Hepatitis C, Chronic | NA | BeFree | Detail | |
0.005 | Malignant neoplasm of esophagus | NA | BeFree,GAD | Detail | |
0.002 | Impaired left ventricular function | NA | GAD | Detail | |
<0.001 | Carotid Atherosclerosis | NA | BeFree | Detail | |
<0.001 | Fibrosis, Liver | The aim of the present study was to investigate the influence of MPO G-463A and ... | BeFree | 24882572 | Detail |
<0.001 | Malignant neoplasm of pancreas | Polymorphisms of the inflammatory pathway genes MPO -G463A and SOD2 Ala16Val are... | BeFree | 18205184 | Detail |
<0.001 | pancreatic carcinoma | Polymorphisms of the inflammatory pathway genes MPO -G463A and SOD2 Ala16Val are... | BeFree | 18205184 | Detail |
<0.001 | Carcinoma of larynx | NA | BeFree | Detail | |
0.002 | Carcinogenesis | NA | BeFree | Detail | |
<0.001 | Leukemogenesis | NA | BeFree | Detail | |
0.002 | prostate carcinoma | NA | BeFree | Detail | |
<0.001 | Epithelial ovarian cancer | NA | BeFree | Detail | |
0.003 | breast carcinoma | For example, among MPO variant allele carriers, obesity was associated with a tw... | BeFree | 25703993 | Detail |
0.009 | Carcinoma of lung | HapMap-based study on the association between MPO and GSTP1 gene polymorphisms a... | BeFree | 24786234 | Detail |
<0.001 | colon carcinoma | NA | BeFree | Detail | |
0.001 | stomach carcinoma | NA | BeFree | Detail | |
<0.001 | Carcinoma of bladder | NA | BeFree | Detail | |
<0.001 | Dissecting aneurysm of the thoracic aorta | NA | BeFree | Detail | |
<0.001 | adult acute lymphocytic leukemia | NA | BeFree | Detail | |
0.003 | brain infarction | NA | BeFree,LHGDN | Detail | |
<0.001 | Spots on skin | NA | BeFree | Detail | |
0.006 | Helicobacter pylori infection | NA | BeFree,GAD | Detail | |
<0.001 | Endothelial dysfunction | NA | BeFree | Detail | |
0.003 | Hyperkeratosis | NA | BeFree,GAD | Detail | |
<0.001 | Cerebral Aneurysm | Myeloperoxidase is increased in human cerebral aneurysms and increases formation... | BeFree | 25922506 | Detail |
0.004 | Acute coronary syndrome | As myeloperoxidase is a prognostic marker of coronary events, the MAPK14 variant... | BeFree,LHGDN | 25164947 | Detail |
0.004 | Acute coronary syndrome | CXCL4 (in association with heparin treatment) and MPO declined over 6 hours duri... | BeFree,LHGDN | 25183015 | Detail |
0.120 | Arthritis, Experimental | NA | CTD_human | Detail | |
0.005 | Malignant neoplasm of ovary | NA | BeFree,GAD | Detail | |
<0.001 | diffuse scleroderma | NA | BeFree | Detail | |
0.120 | major depressive disorder | NA | BeFree,CTD_human | Detail | |
<0.001 | Precursor B-cell lymphoblastic leukemia | NA | BeFree | Detail | |
<0.001 | Necrotizing vasculitis | NA | BeFree | Detail | |
<0.001 | autoimmune vasculitis | NA | BeFree | Detail | |
<0.001 | Infiltrating Cervical Carcinoma | A sample of 100 patients with invasive cervical cancer and 122 control women wer... | BeFree | 25701357 | Detail |
<0.001 | Cardiac fibrosis | NA | BeFree | Detail | |
<0.001 | Vascular lesions | NA | BeFree | Detail | |
0.003 | colorectal cancer | NA | BeFree,GAD | Detail | |
0.003 | Cirrhosis | NA | BeFree,GAD | Detail | |
<0.001 | Peripheral Arterial Diseases | NA | BeFree | Detail | |
0.001 | Acute Myeloid Leukemia (AML-M2) | NA | BeFree | Detail | |
0.015 | coronary artery disease | Meta-analysis of myeloperoxidase gene polymorphism and coronary artery disease s... | BeFree,GAD,LHGDN | 24748187 | Detail |
<0.001 | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma | NA | BeFree | Detail | |
0.009 | Precursor Cell Lymphoblastic Leukemia Lymphoma | NA | BeFree,GAD | Detail | |
0.123 | liver carcinoma | NA | BeFree,CTD_human,GAD | Detail | |
<0.001 | Chronic kidney disease stage 5 | NA | BeFree | Detail | |
<0.001 | Microscopic Polyarteritis | NA | BeFree | Detail | |
0.200 | Acute kidney injury | NA | CTD_human,RGD | Detail | |
<0.001 | Extramedullary Hematopoiesis (disorder) | NA | BeFree | Detail | |
0.003 | Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis | Notably, PR3, p24(PR3/MBN), and MPO were synthesized in cultured neutrophils fro... | BeFree | 25060059 | Detail |
0.001 | Promyelocytic leukemia | NA | BeFree | Detail | |
0.002 | Radiotoxicity | NA | GAD | Detail | |
<0.001 | Early-Stage Breast Carcinoma | NA | BeFree | Detail | |
<0.001 | Nonalcoholic Steatohepatitis | NA | BeFree | Detail | |
<0.001 | myelodysplastic syndrome | NA | BeFree | Detail | |
<0.001 | Neutrophilia (disorder) | NA | BeFree | Detail | |
0.005 | Infection | NA | LHGDN | Detail | |
<0.001 | acute pancreatitis | NA | BeFree | Detail | |
0.003 | adenocarcinoma | NA | BeFree,GAD | Detail | |
<0.001 | adenoma | NA | BeFree | Detail | |
0.003 | agranulocytosis | NA | BeFree,GAD | Detail | |
0.138 | Alzheimer's disease | NA | BeFree,CTD_human,GAD,LHGDN | Detail | |
0.003 | Anemia, Sickle Cell | NA | BeFree,LHGDN | Detail | |
<0.001 | Aneurysm | Incidence of aneurysms and subarachnoid hemorrhage was significantly lower in my... | BeFree | 25922506 | Detail |
<0.001 | Fabry disease | NA | BeFree | Detail | |
0.120 | Anoxia | NA | CTD_human | Detail | |
0.006 | arteriosclerosis | We hypothesized that apoA-I oxidation by MPO levels similar to those present in ... | BeFree | 25759391 | Detail |
0.006 | arteriosclerosis | Therapeutic Potential of Ocimum tenuiflorum as MPO Inhibitor with Implications f... | BeFree | 25764050 | Detail |
0.121 | rheumatoid arthritis | Neutrophils from RA cases exhibited increased spontaneous NET formation in vitro... | BeFree,CTD_human | 24928093 | Detail |
<0.001 | asbestosis | NA | BeFree | Detail | |
0.011 | asthma | NA | BeFree,GAD | Detail | |
0.028 | atherosclerosis | We hypothesized that apoA-I oxidation by MPO levels similar to those present in ... | BeFree,GAD,LHGDN | 25759391 | Detail |
0.028 | atherosclerosis | Therapeutic Potential of Ocimum tenuiflorum as MPO Inhibitor with Implications f... | BeFree,GAD,LHGDN | 25764050 | Detail |
<0.001 | Autoimmune Diseases | NA | BeFree | Detail | |
0.003 | Bacterial Infections | NA | BeFree,GAD | Detail | |
<0.001 | Behcet Syndrome | NA | BeFree | Detail | |
0.002 | Biliary Tract Neoplasm | NA | GAD | Detail | |
0.010 | Malignant neoplasm of urinary bladder | NA | BeFree,GAD | Detail | |
0.122 | Bladder Neoplasm | NA | CTD_human,GAD | Detail | |
0.120 | Brain Diseases | NA | CTD_human | Detail | |
0.002 | Brain Neoplasms | NA | GAD | Detail | |
0.022 | Malignant neoplasm of breast | For example, among MPO variant allele carriers, obesity was associated with a tw... | BeFree,GAD | 25703993 | Detail |
0.002 | bronchitis | NA | GAD | Detail | |
<0.001 | bronchopulmonary dysplasia | The exaggerated BPD-like phenotype observed in hyperoxia-exposed LysM-Cre/Foxm1(... | BeFree | 25275225 | Detail |
<0.001 | Malignant tumor of colon | NA | BeFree | Detail | |
<0.001 | Malignant neoplasm of larynx | NA | BeFree | Detail | |
<0.001 | Rectal Carcinoma | NA | BeFree | Detail | |
<0.001 | Malignant neoplasm of skin | NA | BeFree | Detail | |
<0.001 | Non-small cell lung carcinoma | NA | BeFree | Detail |
Annotation
Annotations
Descrption | Source | Links |
---|---|---|
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Association of myeloperoxidase polymorphism (G463A) with cervix cancer. | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
The present study demonstrated that R1 alleviated the severity of dextran sulfate sodium-induced col... | DisGeNET | Detail |
TNBS induced colitis in the rats was confirmed with weight loss (13.7 ± 3.2 g) and increased myelope... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Meta-analysis of myeloperoxidase gene polymorphism and coronary artery disease susceptibility. | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Myeloperoxidase gene expression and cognitive functions in depression. | DisGeNET | Detail |
Myeloperoxidase gene expression and cognitive functions in depression. | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
An association between MPO -463 G/A polymorphism and type 2 diabetes. | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
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Myeloperoxidase gene polymorphism predicts fibrosis severity in women with hepatitis C. | DisGeNET | Detail |
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LPS plus hyperinflation (double-hit) increased all ALI parameters (ELW, EVPE, permeability index, MP... | DisGeNET | Detail |
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In conclusion, we here demonstrate, exemplarily for MPO, that leukemia-derived HLA ligands can be se... | DisGeNET | Detail |
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Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), m... | DisGeNET | Detail |
Genotyping for glutathione S-transferase micro1 (GSTM1), glutathione S-transferase theta1 (GSTT1), m... | DisGeNET | Detail |
Validation of the gene expression levels of ELANE (neutrophil elastase) and MPO (myeloperoxidase) in... | DisGeNET | Detail |
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We enrolled 1977 Japanese type 2 diabetic subjects without history of CVD (males 66.1%, 59.5 ± 10.0 ... | DisGeNET | Detail |
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We enrolled 1977 Japanese type 2 diabetic subjects without history of CVD (males 66.1%, 59.5 ± 10.0 ... | DisGeNET | Detail |
Effect of the myeloperoxidase inhibitor AZD3241 on microglia: a PET study in Parkinson's disease. | DisGeNET | Detail |
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Incidence of aneurysms and subarachnoid hemorrhage was significantly lower in myeloperoxidase knocko... | DisGeNET | Detail |
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Proteinase 3 (PR3) and myeloperoxidase (MPO) are two major autoantigens in patients with vasculitis ... | DisGeNET | Detail |
Autoantigen excision, a novel method to detect autoantibody epitopes using mass spectrometry, not on... | DisGeNET | Detail |
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Association of single nucleotide polymorphisms in MPO and COX genes with oral lichen planus. | DisGeNET | Detail |
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HapMap-based study on the association between MPO and GSTP1 gene polymorphisms and lung cancer susce... | DisGeNET | Detail |
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Association of myeloperoxidase polymorphism (G463A) with cervix cancer. | DisGeNET | Detail |
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The MPO -463 G/A polymorphism in the stable angina pectoris subgroup was evaluated in 3 studies and ... | DisGeNET | Detail |
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After multivariate analysis adjustment, the GG genotype of MPO and the presence of metabolic syndrom... | DisGeNET | Detail |
Investigation of genetic variation in MAPK11 and MAPK14 genes using additive genetic models in linea... | DisGeNET | Detail |
Relation of myeloperoxidase-463G/A polymorphism with metabolic syndrome and its component traits in ... | DisGeNET | Detail |
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The aim of the present study was to investigate the influence of MPO G-463A and SOD2 Ala16Val polymo... | DisGeNET | Detail |
Polymorphisms of the inflammatory pathway genes MPO -G463A and SOD2 Ala16Val are associated with ele... | DisGeNET | Detail |
Polymorphisms of the inflammatory pathway genes MPO -G463A and SOD2 Ala16Val are associated with ele... | DisGeNET | Detail |
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For example, among MPO variant allele carriers, obesity was associated with a twofold increased risk... | DisGeNET | Detail |
HapMap-based study on the association between MPO and GSTP1 gene polymorphisms and lung cancer susce... | DisGeNET | Detail |
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Myeloperoxidase is increased in human cerebral aneurysms and increases formation and rupture of cere... | DisGeNET | Detail |
As myeloperoxidase is a prognostic marker of coronary events, the MAPK14 variant may provide a mecha... | DisGeNET | Detail |
CXCL4 (in association with heparin treatment) and MPO declined over 6 hours during ACS. | DisGeNET | Detail |
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A sample of 100 patients with invasive cervical cancer and 122 control women were genotyped for MPO ... | DisGeNET | Detail |
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Meta-analysis of myeloperoxidase gene polymorphism and coronary artery disease susceptibility. | DisGeNET | Detail |
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Notably, PR3, p24(PR3/MBN), and MPO were synthesized in cultured neutrophils from patients with acti... | DisGeNET | Detail |
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Incidence of aneurysms and subarachnoid hemorrhage was significantly lower in myeloperoxidase knocko... | DisGeNET | Detail |
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We hypothesized that apoA-I oxidation by MPO levels similar to those present in the artery walls in ... | DisGeNET | Detail |
Therapeutic Potential of Ocimum tenuiflorum as MPO Inhibitor with Implications for Atherosclerosis P... | DisGeNET | Detail |
Neutrophils from RA cases exhibited increased spontaneous NET formation in vitro, associated with el... | DisGeNET | Detail |
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We hypothesized that apoA-I oxidation by MPO levels similar to those present in the artery walls in ... | DisGeNET | Detail |
Therapeutic Potential of Ocimum tenuiflorum as MPO Inhibitor with Implications for Atherosclerosis P... | DisGeNET | Detail |
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For example, among MPO variant allele carriers, obesity was associated with a twofold increased risk... | DisGeNET | Detail |
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The exaggerated BPD-like phenotype observed in hyperoxia-exposed LysM-Cre/Foxm1(-/-) mice was associ... | DisGeNET | Detail |
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Overlapped Transcript Coordinates
Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
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Overlapped Transcript
Gene | Transcript ID | Chromosome | Start | Stop | Links |
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- Gene
- -
- dbSNP
- rs386493716 dbSNP
- Genome
- hg38
- Position
- chr17:58,269,855-58,280,935
- Variant Type
- snv
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