Acute Undifferentiated Leukemia

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Information
Disease name
Acute Undifferentiated Leukemia
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT00557193 Active, not recruiting Phase 3 Combination Chemotherapy With or Without Lestaurtinib in Treating Younger Patients With Newly Diagnosed Acute Lymphoblastic Leukemia January 15, 2008 June 28, 2024
NCT05326516 Active, not recruiting Phase 1 A Study of Revumenib in Combination With Chemotherapy in Participants With R/R Acute Leukemia March 9, 2022 June 2024
NCT02220985 Active, not recruiting Phase 2 Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors in Preventing GVHD February 3, 2015 April 1, 2025
NCT00061945 Completed Phase 1/Phase 2 Alemtuzumab and Combination Chemotherapy in Treating Patients With Untreated Acute Lymphoblastic Leukemia June 2003 October 2012
NCT00079404 Completed Phase 1 17-N-Allylamino-17-Demethoxygeldanamycin in Treating Young Patients With Relapsed or Refractory Solid Tumors or Leukemia March 2004
NCT00098826 Completed Phase 1 SB-715992 in Treating Patients With Acute Leukemia, Chronic Myelogenous Leukemia, or Advanced Myelodysplastic Syndromes December 2004
NCT00112593 Completed N/A Fludarabine and Total-Body Irradiation Followed By Donor Stem Cell Transplant and Cyclosporine and Mycophenolate Mofetil in Treating HIV-Positive Patients With or Without Cancer November 1999
NCT00118352 Completed Phase 2 Alemtuzumab, Fludarabine Phosphate, and Total-Body Irradiation Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer March 2005 May 26, 2015
NCT00006251 Completed Phase 1/Phase 2 Fludarabine Phosphate, Low-Dose Total-Body Irradiation, and Donor Stem Cell Transplant Followed by Cyclosporine, Mycophenolate Mofetil, Donor Lymphocyte Infusion in Treating Patients With Hematopoietic Cancer May 2000
NCT00459212 Completed Phase 1 GTI-2040 in Treating Patients With Relapsed, Refractory, or High-Risk Acute Leukemia, High-Grade Myelodysplastic Syndromes, or Refractory or Blastic Phase Chronic Myelogenous Leukemia March 2007
NCT00606216 Completed Structural Imaging and Cognitive Functions in Adult Stem Cell Transplant Recipients Treated With Chemotherapy Alone or in Combination With Radiotherapy January 2007 December 2015
NCT00890747 Completed Phase 1 Sunitinib Malate in Treating HIV-Positive Patients With Cancer Receiving Antiretroviral Therapy August 2009
NCT00898079 Completed Collecting and Storing Malignant, Borderline Malignant Neoplasms, and Related Samples From Young Patients With Cancer October 13, 2003 June 30, 2018
NCT01053494 Completed N/A Massage Therapy Given by Caregiver in Treating Quality of Life of Young Patients Undergoing Treatment for Cancer April 2010 February 2012
NCT01199562 Completed Infection Prophylaxis and Management in Treating Cytomegalovirus (CMV) Infection in Patients With Hematologic Malignancies Previously Treated With Donor Stem Cell Transplant December 2010 December 2013
NCT01231919 Completed Phase 1 MK2206 in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Leukemia January 2011
NCT01273766 Completed Phase 2 Deferasirox in Treating Iron Overload Caused By Blood Transfusions in Patients With Hematologic Malignancies January 2011 December 2014
NCT01858740 Completed Phase 2 Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts in Preventing GVHD in Children April 10, 2014 July 30, 2023
NCT02135874 Completed Phase 2 Clofarabine, Idarubicin, Cytarabine, Vincristine Sulfate, and Dexamethasone in Treating Patients With Newly Diagnosed or Relapsed Mixed Phenotype Acute Leukemia October 27, 2014 February 21, 2023
NCT01869777 Completed N/A Bioelectrical Impedance Measurement for Predicting Treatment Outcome in Patients With Newly Diagnosed Acute Leukemia July 2013 May 2020
NCT00014235 Completed N/A Fludarabine Phosphate and Total-Body Radiation Followed by Donor Peripheral Blood Stem Cell Transplant and Immunosuppression in Treating Patients With Hematologic Malignancies December 2000
NCT00025415 Completed Phase 1 Imatinib Mesylate in Treating Patients With Advanced Cancer and Liver Dysfunction August 2001
NCT05589896 Recruiting Phase 1/Phase 2 A First-in-Human Study of HLA-Partially to Fully Matched Allogenic Cryopreserved Deceased Donor Bone Marrow Transplantation for Patients With Hematologic Malignancies March 30, 2024 August 2025
NCT03779854 Recruiting Phase 2 Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant August 29, 2019 December 31, 2025
NCT05476770 Recruiting Phase 1 Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies November 11, 2022 November 11, 2027
NCT05322850 Suspended Phase 1/Phase 2 Phase I/II Trial: Engineered Donor Graft (Orca Q) for Pediatric Hematopoietic Cell Transplant (HCT) August 16, 2022 September 2027
NCT03326921 Suspended Phase 1 HA-1 T TCR T Cell Immunotherapy for the Treatment of Patients With Relapsed or Refractory Acute Leukemia After Donor Stem Cell Transplant February 23, 2018 July 16, 2028
NCT00387426 Terminated Phase 2 Sunitinib in Treating Patients With Idiopathic Myelofibrosis September 2006 February 2009
NCT00933985 Terminated Phase 1 Obatoclax Mesylate, Vincristine Sulfate, Doxorubicin Hydrochloride, and Dexrazoxane Hydrochloride in Treating Young Patients With Relapsed or Refractory Solid Tumors, Lymphoma, or Leukemia June 2009 April 2013
NCT01028716 Terminated Phase 2 Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies May 19, 2010 October 7, 2021
NCT05170828 Withdrawn Phase 1 Cryopreserved MMUD BM With PTCy for Hematologic Malignancies September 2022 November 2024
OrphaNumber from OrphaNet (Orphanet)
98835