Annotation Detail
Information
- Associated Genes
- MPO
- Associated Variants
-
MPO MUTATION
MPO MUTATION - Associated Disease
- Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
- Source Database
- DisGeNET
- Description
- Notably, PR3, p24(PR3/MBN), and MPO were synthesized in cultured neutrophils from patients with active ANCA-associated vasculitis, indicating that increased transcription results in newly synthesized autoantigens in peripheral neutrophils of patients.
- Pubmed
- 25060059
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 8
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00325730246496364
Drugs