Annotation Detail

Information
Associated Genes
MPO
Associated Variants
MPO MUTATION
MPO MUTATION
Associated Disease
arteriosclerosis
Source Database
DisGeNET
Description
We hypothesized that apoA-I oxidation by MPO levels similar to those present in the artery walls in atherosclerosis can promote apoA-I structural changes and amyloid fibril formation.
Pubmed
25759391
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
6
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00624316305784698
Drugs