Annotation Detail
Information
- Associated Genes
- MPO
- Associated Variants
-
MPO MUTATION
MPO MUTATION - Associated Disease
- colitis
- Source Database
- DisGeNET
- Description
- The present study demonstrated that R1 alleviated the severity of dextran sulfate sodium-induced colitis in mice by decreasing the activity of myeloperoxidase, the production of cytokines, the expression of proinflammatory genes, and the phosphorylation of IκB kinase, IκBα, and p65 in the colon.
- Pubmed
- 25472953
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 3
- Original source reporting the Gene Disease association
- BeFree,CTD_human
- DisGENET score for the Gene Disease association
- 0.122714418720803
Drugs