Annotation Detail
Information
- Associated Genes
- MPO
- Associated Variants
-
MPO MUTATION
MPO MUTATION - Associated Disease
- bronchopulmonary dysplasia
- Source Database
- DisGeNET
- Description
- The exaggerated BPD-like phenotype observed in hyperoxia-exposed LysM-Cre/Foxm1(-/-) mice was associated with increased expression of neutrophil-derived myeloperoxidase, proteinase 3, and cathepsin g, all of which are critical for lung remodeling and inflammation.
- Pubmed
- 25275225
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 8
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs