Annotation Detail

Information
Associated Genes
MPO
Associated Variants
MPO MUTATION
MPO MUTATION
Associated Disease
Acute coronary syndrome
Source Database
DisGeNET
Description
As myeloperoxidase is a prognostic marker of coronary events, the MAPK14 variant may provide a mechanistic link between p38 map kinase and these events, providing information consistent with current indication of Losmapimod for acute coronary syndrome.
Pubmed
25164947
Section of the abstract supporting the evidence
CONCLUSIONS
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree,LHGDN
DisGENET score for the Gene Disease association
0.00353867585870808
Drugs