chr19:40991282:> Detail (hg38)
Information
Genome
Assembly | Position |
---|---|
hg19 | chr19:41,497,187-41,524,303 |
hg38 | chr19:40,991,282-41,018,398 |
HGVS
Type | Transcript | Protein |
---|---|---|
Summary
MGeND
Clinical significance | |
Variant entry | |
GWAS entry | |
Disease area statistics | Show details |
Frequency
[No Data.]
Prediction
[No Data.]
ClinVar
Clinical Significance | |
Review star | [No Data.] |
Show details |
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
Score | Disease name | Description | Source | Pubmed | Links |
---|---|---|---|---|---|
<0.001 | squamous cell carcinoma | NA | BeFree | Detail | |
0.005 | Cardiovascular Diseases | NA | BeFree,GAD | Detail | |
<0.001 | CNS disorder | NA | BeFree | Detail | |
<0.001 | Primary biliary cirrhosis | NA | BeFree | Detail | |
<0.001 | cholera | NA | BeFree | Detail | |
0.080 | cholestasis | NA | BeFree,CTD_mouse | Detail | |
<0.001 | choriocarcinoma | NA | BeFree | Detail | |
<0.001 | Congenital chromosomal disease | NA | BeFree | Detail | |
<0.001 | Bronchitis, Chronic | NA | BeFree | Detail | |
0.002 | colorectal carcinoma | NA | BeFree | Detail | |
<0.001 | Coronary Arteriosclerosis | NA | BeFree | Detail | |
<0.001 | Coronary heart disease | NA | BeFree | Detail | |
<0.001 | craniosynostosis | NA | BeFree | Detail | |
<0.001 | Infection by Cryptococcus neoformans | NA | BeFree | Detail | |
0.002 | Mental Depression | The usefulness of genotyping cytochrome P450 enzymes in the treatment of depress... | BeFree | 25554071 | Detail |
0.002 | depressive disorder | The usefulness of genotyping cytochrome P450 enzymes in the treatment of depress... | BeFree | 25554071 | Detail |
<0.001 | scleroderma | NA | BeFree | Detail | |
<0.001 | Diabetes | NA | BeFree | Detail | |
<0.001 | diabetes mellitus | NA | BeFree | Detail | |
0.080 | Diabetes Mellitus, Experimental | NA | CTD_mouse | Detail | |
0.001 | Diabetes Mellitus, Non-Insulin-Dependent | NA | BeFree | Detail | |
<0.001 | Down syndrome | NA | BeFree | Detail | |
<0.001 | Drug abuse | NA | BeFree | Detail | |
<0.001 | Endocrine System Diseases | NA | BeFree | Detail | |
<0.001 | endometrial hyperplasia | To explore the possible significance of aromatase P450 in endometrial hyperplasi... | BeFree | 25374239 | Detail |
0.004 | endometriosis | NA | BeFree | Detail | |
<0.001 | Toxic Epidermal Necrolysis | NA | BeFree | Detail | |
0.004 | epilepsy | NA | BeFree,GAD | Detail | |
<0.001 | peptic esophagitis | Proton-pump inhibitor (PPI) metabolized by P450 2C19 (CYP2C19) is the chief medi... | BeFree | 25910560 | Detail |
<0.001 | Fatty Liver | NA | BeFree | Detail | |
<0.001 | fibrosarcoma | NA | BeFree | Detail | |
<0.001 | Female Genital Diseases | NA | BeFree | Detail | |
<0.001 | glaucoma | NA | BeFree | Detail | |
<0.001 | primary angle-closure glaucoma | NA | BeFree | Detail | |
<0.001 | glioblastoma | NA | BeFree | Detail | |
<0.001 | Glioma | NA | BeFree | Detail | |
<0.001 | glomerulonephritis | NA | BeFree | Detail | |
0.002 | Graft-vs-Host Disease | NA | GAD | Detail | |
<0.001 | Hallucinations | NA | BeFree | Detail | |
<0.001 | Heart failure | NA | BeFree | Detail | |
<0.001 | congestive heart failure | NA | BeFree | Detail | |
<0.001 | hepatitis | NA | BeFree | Detail | |
<0.001 | hepatitis A | NA | BeFree | Detail | |
0.002 | hepatitis C | NA | BeFree | Detail | |
<0.001 | Herpes NOS | NA | BeFree | Detail | |
<0.001 | Herpes Simplex Infections | NA | BeFree | Detail | |
0.086 | HIV Infections | Proportions with HIV-1 RNA <50 or <200 copies/mL did not differ across 10 CYP2B6... | BeFree,GAD | 24695352 | Detail |
0.086 | HIV Infections | Secondary metabolism pathway polymorphisms and plasma efavirenz concentrations i... | BeFree,GAD | 24729586 | Detail |
0.086 | HIV Infections | CYP2B6 516G>T (rs3745274) and smoking status are associated with efavirenz plasm... | BeFree,GAD | 24831655 | Detail |
0.086 | HIV Infections | CYP2B6 c.983T>C polymorphism is associated with nevirapine hypersensitivity in M... | BeFree,GAD | 25147095 | Detail |
<0.001 | hydrophthalmos | NA | BeFree | Detail | |
<0.001 | Hyperbilirubinemia | NA | BeFree | Detail | |
<0.001 | Hypercholesterolemia | NA | BeFree | Detail | |
0.004 | Hypertensive disease | Cytochrome P450 eicosanoids in hypertension and renal disease. | BeFree | 25427230 | Detail |
<0.001 | Immunologic Deficiency Syndromes | NA | BeFree | Detail | |
<0.001 | male infertility | NA | BeFree | Detail | |
0.002 | Inflammation | NA | GAD | Detail | |
<0.001 | ischemia | NA | BeFree | Detail | |
<0.001 | Kidney Diseases | Cytochrome P450 eicosanoids in hypertension and renal disease. | BeFree | 25427230 | Detail |
0.123 | Kidney Failure, Chronic | NA | BeFree,CTD_human,GAD | Detail | |
<0.001 | Polycystic Kidney Diseases | These studies indicate that CYP P450 metabolites of arachidonic acid play an imp... | BeFree | 25427230 | Detail |
0.001 | Fibroid Tumor | NA | BeFree | Detail | |
0.003 | leukemia | NA | BeFree,GAD | Detail | |
0.003 | chronic lymphocytic leukemia | NA | BeFree,GAD | Detail | |
0.086 | HIV Infections | Prevalence of MDR1 C3435T and CYP2B6 G516T polymorphisms among HIV-1 infected So... | BeFree | 22297601 | Detail |
<0.001 | Acute lymphocytic leukemia | NA | BeFree | Detail | |
0.003 | Leukemia, Myelocytic, Acute | NA | BeFree,GAD | Detail | |
<0.001 | myeloid leukemia | NA | BeFree | Detail | |
<0.001 | Myeloid Leukemia, Chronic | NA | BeFree | Detail | |
<0.001 | acute promyelocytic leukemia | NA | BeFree | Detail | |
<0.001 | leukopenia | NA | BeFree | Detail | |
<0.001 | Leydig cell tumor | NA | BeFree | Detail | |
0.001 | liver cirrhosis | NA | BeFree | Detail | |
0.005 | Liver diseases | NA | BeFree,GAD | Detail | |
0.003 | Liver neoplasms | NA | BeFree | Detail | |
<0.001 | long QT syndrome | NA | BeFree | Detail | |
0.003 | Lung Neoplasms | NA | BeFree,GAD | Detail | |
0.002 | Lupus Erythematosus, Systemic | Genetic polymorphisms of glutathione S-transferases and cytochrome P450 enzymes ... | BeFree | 24981927 | Detail |
0.008 | lupus nephritis | NA | BeFree,GAD | Detail | |
<0.001 | lymphoma | Cytochrome P450 2B6*5 Increases Relapse after Cyclophosphamide-Containing Condit... | BeFree | 25677220 | Detail |
0.003 | malaria | Genetic variability of CYP2B6 polymorphisms in southeast Iranian population: imp... | BeFree,GAD | 25305768 | Detail |
<0.001 | Malignant neoplasm of stomach | NA | BeFree | Detail | |
<0.001 | melanoma | NA | BeFree | Detail | |
<0.001 | premature menopause | NA | BeFree | Detail | |
<0.001 | Metabolic Diseases | NA | BeFree | Detail | |
<0.001 | multiple myeloma | NA | BeFree | Detail | |
<0.001 | myopathy | NA | BeFree | Detail | |
0.003 | myocardial infarction | NA | BeFree,GAD | Detail | |
<0.001 | Myotonic dystrophy | NA | BeFree | Detail | |
0.002 | narcolepsy | NA | GAD | Detail | |
<0.001 | Neoplasm Metastasis | Previous studies suggested that cytochrome P450 participated in the tumor metast... | BeFree | 25424204 | Detail |
0.005 | Neoplasms, Germ Cell and Embryonal | NA | GAD | Detail | |
<0.001 | nervous system disorder | NA | BeFree | Detail | |
0.001 | nicotine dependence | CYP2B6 gene single-nucleotide polymorphisms in an Italian population sample and ... | BeFree | 25489907 | Detail |
<0.001 | obesity | Altered cytochrome P450 activities and expression levels in the liver and intest... | BeFree | 25998026 | Detail |
<0.001 | osteosarcoma | NA | BeFree | Detail | |
<0.001 | ovarian carcinoma | Resistance arises from the oxidation of anticancer drugs by CYP1B1, a cytochrome... | BeFree | 25516145 | Detail |
0.001 | Ovarian Diseases | NA | BeFree | Detail | |
<0.001 | Pain | NA | BeFree | Detail | |
<0.001 | Pancreatic Neoplasm | NA | BeFree | Detail | |
<0.001 | Peutz-Jeghers syndrome | NA | BeFree | Detail | |
<0.001 | polycythemia vera | NA | BeFree | Detail | |
0.003 | Prostatic Neoplasms | NA | LHGDN | Detail | |
<0.001 | Psychotic Disorders | NA | BeFree | Detail | |
<0.001 | kidney failure | NA | BeFree | Detail | |
<0.001 | rickets | NA | BeFree | Detail | |
0.002 | schizophrenia | NA | BeFree | Detail | |
<0.001 | paranoid schizophrenia | NA | BeFree | Detail | |
<0.001 | systemic scleroderma | NA | BeFree | Detail | |
<0.001 | Skin Neoplasms | NA | BeFree | Detail | |
<0.001 | ankylosing spondylitis | NA | BeFree | Detail | |
<0.001 | Stevens-Johnson syndrome | An association between the CYP2B6 c.983T>C polymorphism and nevirapine-induced S... | BeFree | 25147095 | Detail |
<0.001 | stomatitis | NA | BeFree | Detail | |
0.003 | Cerebrovascular accident | NA | BeFree,GAD | Detail | |
<0.001 | sudden infant death syndrome | NA | BeFree | Detail | |
0.002 | thrombosis | NA | GAD | Detail | |
<0.001 | Thyroid Neoplasm | NA | BeFree | Detail | |
0.005 | Tobacco use disorder | NA | GAD | Detail | |
<0.001 | Torsades de pointes | NA | BeFree | Detail | |
0.008 | tuberculosis | NA | BeFree,GAD | Detail | |
<0.001 | Urogenital Abnormalities | NA | BeFree | Detail | |
0.001 | Uterine Fibroids | NA | BeFree | Detail | |
0.001 | Virilism | NA | BeFree | Detail | |
<0.001 | Virus Diseases | NA | BeFree | Detail | |
0.006 | Ovarian Failure, Premature | NA | BeFree,GAD | Detail | |
<0.001 | acute leukemia | NA | BeFree | Detail | |
<0.001 | hemorrhagic cystitis | NA | BeFree | Detail | |
<0.001 | Polyglandular Type I Autoimmune Syndrome | NA | BeFree | Detail | |
<0.001 | Deep Vein Thrombosis | NA | BeFree | Detail | |
<0.001 | Chronic pain | Opioid regimens in patients with chronic pain with multiple cytochrome P450 defe... | BeFree | 25985808 | Detail |
<0.001 | Myocardial Ischemia | NA | BeFree | Detail | |
<0.001 | Primary ulcer of intestine | NA | BeFree | Detail | |
<0.001 | Adenocarcinoma of lung (disorder) | NA | BeFree | Detail | |
0.001 | lingual-facial-buccal dyskinesia | NA | BeFree | Detail | |
<0.001 | Malignant neoplasm of mouth | NA | BeFree | Detail | |
<0.001 | acute myocardial infarction | Cytochrome p450 gene variants, race, and mortality among clopidogrel-treated pat... | BeFree | 24762860 | Detail |
<0.001 | Porphyrias, Hepatic | NA | BeFree | Detail | |
<0.001 | Agenesis of corpus callosum | NA | BeFree | Detail | |
<0.001 | Lung Diseases, Interstitial | NA | BeFree | Detail | |
<0.001 | hyperandrogenism | NA | BeFree | Detail | |
<0.001 | Lichen Planus, Oral | Subgrouping of patients with oral lichen planus according to cytochrome P450 enz... | BeFree | 25240994 | Detail |
<0.001 | hepatoblastoma | NA | BeFree | Detail | |
<0.001 | adrenal cortical adenoma | NA | BeFree | Detail | |
<0.001 | adrenocortical carcinoma | NA | BeFree | Detail | |
<0.001 | Cervical Intraepithelial Neoplasia | NA | BeFree | Detail | |
0.120 | gliosarcoma | NA | CTD_human | Detail | |
<0.001 | childhood rhabdomyosarcoma | NA | BeFree | Detail | |
<0.001 | Adult Acute Myeloblastic Leukemia | NA | BeFree | Detail | |
<0.001 | Lip and oral cavity carcinoma | NA | BeFree | Detail | |
<0.001 | Neurologic Symptoms | NA | BeFree | Detail | |
<0.001 | pancreatic carcinoma | NA | BeFree | Detail | |
<0.001 | Endometriosis of pelvis | NA | BeFree | Detail | |
0.002 | Hepatitis, Autoimmune | NA | BeFree | Detail | |
0.006 | Malignant neoplasm of lung | NA | BeFree | Detail | |
<0.001 | Food-Drug Interactions | NA | BeFree | Detail | |
<0.001 | Ambiguous genitalia | NA | BeFree | Detail | |
<0.001 | Adrenal hyperplasia, congenital, type 5 | NA | BeFree | Detail | |
<0.001 | Vitamin D-dependent rickets, type 1 | NA | BeFree | Detail | |
<0.001 | Endometrioma | NA | BeFree | Detail | |
<0.001 | Isosexual precocious puberty | NA | BeFree | Detail | |
<0.001 | Toxic Epidermal Necrolysis | CYP2B6 G516T and T983C single nucleotide polymorphisms (SNPs) were found to be a... | BeFree | 23774940 | Detail |
<0.001 | Stevens-Johnson syndrome | CYP2B6 G516T and T983C single nucleotide polymorphisms (SNPs) were found to be a... | BeFree | 23774940 | Detail |
<0.001 | Familial Alzheimer Disease (FAD) | NA | BeFree | Detail | |
<0.001 | Stage IV Ovarian Carcinoma | NA | BeFree | Detail | |
<0.001 | Cancer of Head and Neck | NA | BeFree | Detail | |
<0.001 | Solid tumour | NA | BeFree | Detail | |
<0.001 | Tumor necrosis | NA | BeFree | Detail | |
<0.001 | Fibrolamellar hepatocellular carcinoma | NA | BeFree | Detail | |
<0.001 | Leydig cell tumor, benign | NA | BeFree | Detail | |
<0.001 | Glaucoma, Primary Open Angle | NA | BeFree | Detail | |
<0.001 | Deep vein thrombosis of lower limb | NA | BeFree | Detail | |
<0.001 | endometriosis of uterus | NA | BeFree | Detail | |
<0.001 | Malignant neoplasm of liver | NA | BeFree | Detail | |
<0.001 | Adenoma of lung | NA | BeFree | Detail | |
<0.001 | Malignant neoplasm of pancreas | NA | BeFree | Detail | |
<0.001 | Nonorganic psychosis | NA | BeFree | Detail | |
<0.001 | Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site | NA | BeFree | Detail | |
0.006 | Malignant neoplasm of prostate | NA | BeFree,GAD | Detail | |
0.003 | Hematologic Neoplasms | NA | BeFree,GAD | Detail | |
<0.001 | Abnormal involuntary movement | NA | BeFree | Detail | |
<0.001 | Non-alcoholic Fatty Liver Disease | NA | BeFree | Detail | |
0.001 | adrenal cortical hypofunction | NA | BeFree | Detail | |
<0.001 | Congenital Myotonic Dystrophy | NA | BeFree | Detail | |
<0.001 | Skeletal dysplasia | NA | BeFree | Detail | |
<0.001 | Nonorganic psychosis | We report (to our knowledge, for the first time in a child) the emergence of psy... | BeFree | 17968817 | Detail |
<0.001 | Neurologic Symptoms | The CYP2B6 G516T genotype was also associated with central nervous system sympto... | BeFree | 15622315 | Detail |
<0.001 | Psychotic Disorders | We report (to our knowledge, for the first time in a child) the emergence of psy... | BeFree | 17968817 | Detail |
0.086 | HIV Infections | CYP2B6 G516T genotyping in a UK cohort of HIV-positive patients: polymorphism fr... | BeFree | 19486190 | Detail |
0.086 | HIV Infections | Seventy-two adult Chinese HIV-positive treatment-naïve patients were recruited i... | BeFree | 23970651 | Detail |
0.003 | Hematologic Neoplasms | This study demonstrates for the first time that the presence of the CYP2B6 G516T... | BeFree | 16183265 | Detail |
0.086 | HIV Infections | Efavirenz pharmacokinetics in HIV-1-infected children are associated with CYP2B6... | BeFree | 17356468 | Detail |
0.086 | HIV Infections | HIV-infected patients with or without TB who had received combination antiretrov... | BeFree | 24551111 | Detail |
0.086 | HIV Infections | Cytochrome P450 2B6 (CYP2B6) G516T influences nevirapine plasma concentrations i... | BeFree | 17352764 | Detail |
<0.001 | Anovulatory | NA | BeFree | Detail | |
<0.001 | Hypospadias, penoscrotal | NA | BeFree | Detail | |
<0.001 | endometrial carcinoma | NA | BeFree | Detail | |
0.001 | hiv-infection/aids | Genetic variability of CYP2B6 polymorphisms in southeast Iranian population: imp... | BeFree | 25305768 | Detail |
0.002 | Chronic active hepatitis | NA | BeFree | Detail | |
0.002 | Electrocardiogram abnormal | NA | GAD | Detail | |
<0.001 | Neurodegenerative Disorders | NA | BeFree | Detail | |
<0.001 | Hepatitis C, Chronic | NA | BeFree | Detail | |
<0.001 | Malignant glioma | NA | BeFree | Detail | |
<0.001 | Osteosarcoma of bone | NA | BeFree | Detail | |
0.004 | Carcinogenesis | NA | BeFree | Detail | |
<0.001 | Chemical Carcinogenesis | NA | BeFree | Detail | |
<0.001 | Stromal tumor of ovary | NA | BeFree | Detail | |
0.001 | prostate carcinoma | NA | BeFree | Detail | |
<0.001 | Hot flushes | NA | BeFree | Detail | |
<0.001 | Gastro-esophageal reflux disease with esophagitis | Proton-pump inhibitor (PPI) metabolized by P450 2C19 (CYP2C19) is the chief medi... | BeFree | 25910560 | Detail |
0.009 | breast carcinoma | Effects of CYP2B6 genetic polymorphisms in patients receiving cyclophosphamide c... | BeFree | 25428516 | Detail |
0.007 | Carcinoma of lung | NA | BeFree | Detail | |
<0.001 | Malignant neoplasm of gastrointestinal tract | NA | BeFree | Detail | |
0.001 | Tardive Dyskinesia | NA | BeFree | Detail | |
<0.001 | stomach carcinoma | NA | BeFree | Detail | |
0.001 | Carcinoma of bladder | NA | BeFree | Detail | |
<0.001 | Middle Cerebral Artery Occlusion | NA | BeFree | Detail | |
<0.001 | End Stage Liver Disease | To investigate the expression of P450 enzyme genes by using end-stage liver dise... | BeFree | 25024626 | Detail |
<0.001 | Cancer of Digestive System | NA | BeFree | Detail | |
<0.001 | Acute Cerebrovascular Accidents | NA | BeFree | Detail | |
<0.001 | Carcinoma in situ of uterine cervix | NA | BeFree | Detail | |
0.001 | 21-hydroxylase deficiency | NA | BeFree | Detail | |
<0.001 | Testicular malignant germ cell tumor | NA | BeFree | Detail | |
0.005 | Drug-Induced Liver Injury | NA | GAD | Detail | |
<0.001 | Enzyme inhibition disorder | NA | BeFree | Detail | |
<0.001 | Sleeplessness | NA | BeFree | Detail | |
0.005 | ovarian neoplasm | NA | GAD | Detail | |
<0.001 | Ischemic stroke | NA | BeFree | Detail | |
0.003 | Acute coronary syndrome | NA | BeFree,GAD | Detail | |
<0.001 | Colorectal cancer metastatic | Genetic polymorphisms in cytochrome P450 and clinical outcomes of FOLFIRI chemot... | BeFree | 25934339 | Detail |
<0.001 | Hepatic impairment | NA | BeFree | Detail | |
<0.001 | Malignant neoplasm of ovary | Resistance arises from the oxidation of anticancer drugs by CYP1B1, a cytochrome... | BeFree | 25516145 | Detail |
<0.001 | Hepatitis, Drug-Induced | NA | BeFree | Detail | |
<0.001 | Uroporphyrinuria | NA | BeFree | Detail | |
<0.001 | Sporadic porphyria cutanea tarda | NA | BeFree | Detail | |
<0.001 | Deficiency of monooxygenase | NA | BeFree | Detail | |
<0.001 | Precursor B-cell lymphoblastic leukemia | NA | BeFree | Detail | |
<0.001 | Adenoma of large intestine | NA | BeFree | Detail | |
<0.001 | childhood leukemia | NA | BeFree | Detail | |
<0.001 | pancreatic ductal adenocarcinoma | NA | BeFree | Detail | |
<0.001 | Granulosa cell tumor of the ovary | NA | BeFree | Detail | |
<0.001 | Conn Syndrome | NA | BeFree | Detail | |
<0.001 | Congenital absence of germinal epithelium of testes | NA | BeFree | Detail | |
0.010 | Mammary Neoplasms | NA | BeFree,GAD,LHGDN | Detail | |
<0.001 | Hepatocarcinogenesis | NA | BeFree | Detail | |
<0.001 | Xenograft Model | NA | BeFree | Detail | |
0.002 | colorectal cancer | NA | BeFree | Detail | |
0.002 | primary congenital glaucoma | NA | BeFree | Detail | |
<0.001 | Oral Mucositis | NA | BeFree | Detail | |
0.001 | Cirrhosis | NA | BeFree | Detail | |
<0.001 | androgen independent prostate cancer | The analysis of KEGG show that the relevant genes of AIPC transformation partici... | BeFree | 25520106 | Detail |
<0.001 | Peripheral Arterial Diseases | NA | BeFree | Detail | |
<0.001 | ICHTHYOSIS, LAMELLAR, 3 | The pathogenesis of Kava dermopathy may be associated with a functional defect i... | BeFree | 25069767 | Detail |
<0.001 | Bietti crystalline corneoretinal dystrophy | NA | BeFree | Detail | |
<0.001 | Antley-Bixler syndrome with disordered steroidogenesis | NA | BeFree | Detail | |
0.120 | TOBACCO ADDICTION, SUSCEPTIBILITY TO (finding) | NA | CTD_human | Detail | |
<0.001 | Glucocorticoid Deficiency | NA | BeFree | Detail | |
<0.001 | coronary artery disease | NA | BeFree | Detail | |
0.005 | Precursor Cell Lymphoblastic Leukemia Lymphoma | NA | GAD | Detail | |
<0.001 | aromatase excess syndrome | NA | BeFree | Detail | |
0.008 | liver carcinoma | NA | BeFree,LHGDN | Detail | |
<0.001 | WARFARIN SENSITIVITY (disorder) | NA | BeFree | Detail | |
<0.001 | Steatohepatitis | Extracellular matrix and cytochrome P450 gene expression can distinguish steatoh... | BeFree | 24913135 | Detail |
<0.001 | Promyelocytic leukemia | NA | BeFree | Detail | |
0.003 | Antley-Bixler Syndrome, Autosomal Dominant | NA | BeFree | Detail | |
0.002 | Congenital adrenal hyperplasia due to 21 hydroxylase deficiency | NA | BeFree | Detail | |
<0.001 | Cervix Intraepithelial Neoplasia Grade 3 AJCC v7 | NA | BeFree | Detail | |
<0.001 | Nonalcoholic Steatohepatitis | NA | BeFree | Detail | |
<0.001 | Ischemic Cerebrovascular Accident | NA | BeFree | Detail | |
0.120 | EFAVIRENZ, POOR METABOLISM OF | NA | ORPHANET | Detail | |
0.002 | myelodysplastic syndrome | NA | GAD | Detail | |
0.001 | Experimental Organism Basal Cell Carcinoma | NA | BeFree | Detail | |
<0.001 | Pneumonia in children | NA | BeFree | Detail | |
<0.001 | Congenital Abnormality | NA | BeFree | Detail | |
0.007 | acquired immunodeficiency syndrome | NA | GAD | Detail | |
<0.001 | adenoma | NA | BeFree | Detail | |
0.002 | Adrenal gland hypofunction | NA | BeFree | Detail | |
0.004 | congenital adrenal hyperplasia | NA | BeFree | Detail | |
<0.001 | Alcoholic Intoxication, Chronic | NA | BeFree | Detail | |
<0.001 | Alzheimer's disease | CYP2D6 gene encoding CYP2D6 enzyme belonging to the cytochrome P450 system has a... | BeFree | 24909950 | Detail |
<0.001 | aplastic anemia | NA | BeFree | Detail | |
<0.001 | Anxiety Disorders | NA | BeFree | Detail | |
<0.001 | arteriosclerosis | NA | BeFree | Detail | |
<0.001 | Arthritis, Psoriatic | NA | BeFree | Detail | |
<0.001 | rheumatoid arthritis | NA | BeFree | Detail | |
<0.001 | asthma | NA | BeFree | Detail | |
<0.001 | atherosclerosis | NA | BeFree | Detail | |
<0.001 | Autoimmune Diseases | NA | BeFree | Detail | |
<0.001 | Basal Cell Nevus Syndrome | NA | BeFree | Detail | |
<0.001 | Mental disorders | NA | BeFree | Detail | |
<0.001 | biliary atresia | NA | BeFree | Detail | |
0.001 | Malignant neoplasm of urinary bladder | NA | BeFree | Detail | |
<0.001 | Bladder Neoplasm | NA | BeFree | Detail | |
<0.001 | Brain Neoplasms | NA | BeFree | Detail | |
0.021 | Malignant neoplasm of breast | Effects of CYP2B6 genetic polymorphisms in patients receiving cyclophosphamide c... | BeFree,GAD | 25428516 | Detail |
<0.001 | Non-small cell lung carcinoma | NA | BeFree | Detail |
Annotation
Annotations
Descrption | Source | Links |
---|---|---|
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
The usefulness of genotyping cytochrome P450 enzymes in the treatment of depression. | DisGeNET | Detail |
The usefulness of genotyping cytochrome P450 enzymes in the treatment of depression. | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
To explore the possible significance of aromatase P450 in endometrial hyperplasia with a background ... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Proton-pump inhibitor (PPI) metabolized by P450 2C19 (CYP2C19) is the chief medication in reflux eso... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
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Proportions with HIV-1 RNA <50 or <200 copies/mL did not differ across 10 CYP2B6 metabolizer strata. | DisGeNET | Detail |
Secondary metabolism pathway polymorphisms and plasma efavirenz concentrations in HIV-infected adult... | DisGeNET | Detail |
CYP2B6 516G>T (rs3745274) and smoking status are associated with efavirenz plasma concentration in a... | DisGeNET | Detail |
CYP2B6 c.983T>C polymorphism is associated with nevirapine hypersensitivity in Malawian and Ugandan ... | DisGeNET | Detail |
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Cytochrome P450 eicosanoids in hypertension and renal disease. | DisGeNET | Detail |
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Cytochrome P450 eicosanoids in hypertension and renal disease. | DisGeNET | Detail |
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These studies indicate that CYP P450 metabolites of arachidonic acid play an important role in the c... | DisGeNET | Detail |
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Prevalence of MDR1 C3435T and CYP2B6 G516T polymorphisms among HIV-1 infected South African patients... | DisGeNET | Detail |
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Genetic polymorphisms of glutathione S-transferases and cytochrome P450 enzymes as susceptibility fa... | DisGeNET | Detail |
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Cytochrome P450 2B6*5 Increases Relapse after Cyclophosphamide-Containing Conditioning and Autologou... | DisGeNET | Detail |
Genetic variability of CYP2B6 polymorphisms in southeast Iranian population: implications for malari... | DisGeNET | Detail |
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Previous studies suggested that cytochrome P450 participated in the tumor metastasis and migration. | DisGeNET | Detail |
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CYP2B6 gene single-nucleotide polymorphisms in an Italian population sample and relationship with ni... | DisGeNET | Detail |
Altered cytochrome P450 activities and expression levels in the liver and intestines of the monosodi... | DisGeNET | Detail |
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Resistance arises from the oxidation of anticancer drugs by CYP1B1, a cytochrome P450 enzyme overexp... | DisGeNET | Detail |
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An association between the CYP2B6 c.983T>C polymorphism and nevirapine-induced SJS/TEN was observed. | DisGeNET | Detail |
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Opioid regimens in patients with chronic pain with multiple cytochrome P450 defects. | DisGeNET | Detail |
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Cytochrome p450 gene variants, race, and mortality among clopidogrel-treated patients after acute my... | DisGeNET | Detail |
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Subgrouping of patients with oral lichen planus according to cytochrome P450 enzyme phenotype and ge... | DisGeNET | Detail |
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CYP2B6 G516T and T983C single nucleotide polymorphisms (SNPs) were found to be associated with SJS/T... | DisGeNET | Detail |
CYP2B6 G516T and T983C single nucleotide polymorphisms (SNPs) were found to be associated with SJS/T... | DisGeNET | Detail |
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We report (to our knowledge, for the first time in a child) the emergence of psychosis in a 12-year ... | DisGeNET | Detail |
The CYP2B6 G516T genotype was also associated with central nervous system symptoms at week 1 (P = 0.... | DisGeNET | Detail |
We report (to our knowledge, for the first time in a child) the emergence of psychosis in a 12-year ... | DisGeNET | Detail |
CYP2B6 G516T genotyping in a UK cohort of HIV-positive patients: polymorphism frequency and influenc... | DisGeNET | Detail |
Seventy-two adult Chinese HIV-positive treatment-naïve patients were recruited in a study to evaluat... | DisGeNET | Detail |
This study demonstrates for the first time that the presence of the CYP2B6 G516T mutation increases ... | DisGeNET | Detail |
Efavirenz pharmacokinetics in HIV-1-infected children are associated with CYP2B6-G516T polymorphism. | DisGeNET | Detail |
HIV-infected patients with or without TB who had received combination antiretroviral therapy contain... | DisGeNET | Detail |
Cytochrome P450 2B6 (CYP2B6) G516T influences nevirapine plasma concentrations in HIV-infected patie... | DisGeNET | Detail |
NA | DisGeNET | Detail |
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Genetic variability of CYP2B6 polymorphisms in southeast Iranian population: implications for malari... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
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Proton-pump inhibitor (PPI) metabolized by P450 2C19 (CYP2C19) is the chief medication in reflux eso... | DisGeNET | Detail |
Effects of CYP2B6 genetic polymorphisms in patients receiving cyclophosphamide combination chemother... | DisGeNET | Detail |
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To investigate the expression of P450 enzyme genes by using end-stage liver disease samples and trim... | DisGeNET | Detail |
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Genetic polymorphisms in cytochrome P450 and clinical outcomes of FOLFIRI chemotherapy in patients w... | DisGeNET | Detail |
NA | DisGeNET | Detail |
Resistance arises from the oxidation of anticancer drugs by CYP1B1, a cytochrome P450 enzyme overexp... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
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The analysis of KEGG show that the relevant genes of AIPC transformation participate in glutathione ... | DisGeNET | Detail |
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The pathogenesis of Kava dermopathy may be associated with a functional defect in one or more cytoch... | DisGeNET | Detail |
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Extracellular matrix and cytochrome P450 gene expression can distinguish steatohepatitis from steato... | DisGeNET | Detail |
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CYP2D6 gene encoding CYP2D6 enzyme belonging to the cytochrome P450 system has aroused long attentio... | DisGeNET | Detail |
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Effects of CYP2B6 genetic polymorphisms in patients receiving cyclophosphamide combination chemother... | DisGeNET | Detail |
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Overlapped Transcript Coordinates
Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
---|
Overlapped Transcript
Gene | Transcript ID | Chromosome | Start | Stop | Links |
---|
- Gene
- -
- dbSNP
- rs56308434 dbSNP
- Genome
- hg38
- Position
- chr19:40,991,282-41,018,398
- Variant Type
- snv
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