End Stage Liver Disease

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Information
Disease name
End Stage Liver Disease
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT03089840 Active, not recruiting Phase 1/Phase 2 Normothermic Liver Preservation Trial February 24, 2017 June 30, 2025
NCT05195125 Active, not recruiting Phase 1 Use of Direct Peritoneal Resuscitation in High-risk Liver Transplant Recipients February 1, 2022 December 2023
NCT03580629 Active, not recruiting N/A Pilot Study of the Liver Live Donor Champion Program September 18, 2018 December 29, 2024
NCT04220723 Active, not recruiting Evaluation of Frailty and Functional Capacity in End-Stage Liver Disease November 20, 2022 August 16, 2024
NCT01907074 Active, not recruiting Phase 2 Quantitative Liver Function Tests Using Cholates July 2011 December 2025
NCT00678834 Completed Early Phase 1 Human Tissue Distribution of Orally Supplemented Natural Vitamin E Tocotrienol March 2006 June 2012
NCT00687349 Completed Phase 3 Improving Clinician Communication Skills (ICCS) April 2007 March 2013
NCT06320730 Completed Impact of Glycemic Control After Reperfusion on Acute Kidney Injury in Living Donor Liver Transplantation August 25, 2020 March 1, 2021
NCT05238779 Completed An Integrative Model for Palliative Care in End-Stage Liver Disease January 6, 2022 December 12, 2022
NCT01467011 Completed Myfortic, Prograf, and Corticosteroids in de Novo Liver Transplantation December 2010 December 2013
NCT01619475 Completed Adult-to-Adult Living Donor Transplant Cohort Study February 2011 August 2014
NCT01658982 Completed Cardiopulmonary Exercise Testing in Cirrhotic Patients: a Pilot Study August 2012 July 2013
NCT02617498 Completed Early Phase 1 Spray Diathermy Versus Harmonic Scalpel Technique for Hepatic Parenchymal Transection April 2013 November 2015
NCT03516994 Completed N/A Reducing Disparities in the Quality of Advance Care Planning for Older Adults August 1, 2018 April 15, 2024
NCT03557086 Completed N/A A Randomized Controlled Trial of an Advanced Care Planning Video Decision Support Tool for Patients With End-Stage Liver Disease September 28, 2018 March 3, 2020
NCT00547924 Completed Transoesophageal Echocardiography in Liver Transplantation April 2006 January 2010
NCT00604357 Completed Phase 3 CNI-free de Novo Protocol in Patients Undergoing Liver Transplantation With Renal Impairment December 2008 August 2012
NCT02584283 Completed Phase 3 Dual Hypothermic Oxygenated Perfusion of DCD Liver Grafts in Preventing Biliary Complications After Transplantation January 2016 January 2020
NCT03584646 Completed N/A Prehabilitation Intervention to Maximize Early Recovery (PRIMER) in Liver Transplantation February 28, 2018 October 1, 2022
NCT02826460 Completed Psychosocial Risks in Liver Transplant Recipients November 2014 June 2016
NCT03184701 Completed N/A Monitoring of Symptoms and Cognitive Function Using Telehealth April 30, 2016 August 30, 2018
NCT00163657 Completed Phase 4 Study of Liver Transplant For End-Stage Liver Disease Caused By Chronic Hepatitis C Infection July 2002 January 2007
NCT00249652 Completed Phase 1/Phase 2 Transplant and Addiction Project (TAP) - 1 September 2003 September 2009
NCT00374582 Completed N/A End Stage Liver Disease and Body Composition Assessment: Utilizing Bioelectric Impedance Analysis (BIA) September 2006 May 2008
NCT03609411 Completed Splenectomy During Whole Liver Transplantation January 2015 January 2017
NCT05045794 Completed N/A Bridge to HOPE: Hypothermic Oxygenated Perfusion Versus Cold Storage Prior to Liver Transplantation December 16, 2021 June 10, 2024
NCT04925843 Completed Fibrinogen and Intraoperative Bleeding in Liver Transplant July 15, 2019 January 10, 2022
NCT04787276 Completed N/A Efficacy and Safety of E.Coli Nissle 1917 in Patients With Mild (Stage 1-2) or Minimal Hepatic Encephalopathy January 10, 2017 March 15, 2020
NCT04604860 Completed N/A Use of EL-FIT App to Promote Physical Activity September 23, 2020 February 24, 2022
NCT01932918 Completed Antinociceptive Modalities on Ischemia Reperfusion Injury January 2011 July 2015
NCT01933789 Completed N/A Improving Communication About Serious Illness September 2013 December 2016
NCT02367092 Completed N/A Exercise Intervention in Liver Transplant Patients July 2016 December 2019
NCT02444273 Completed N/A The Feasibility of a Prehabilitation Program in the Liver Transplant Population at Barnes-Jewish Hospital October 2014 December 2017
NCT04546048 Completed N/A The Early Strength Training Program in Post-transplant Liver Cases September 19, 2018 August 24, 2019
NCT02504138 Completed Phase 4 A Comparison of Propofol Based Total Intravenous Anesthesia and Desflurane Based Balanced Anesthesia on Hepatic Protection During Living-donor Liver Transplantation June 2014 May 2017
NCT02548130 Completed Impact of MELD Score for 1000 Consecutive Liver Transplantations July 29, 2015 July 21, 2019
NCT00238693 Completed Transplant Patient Registry of Liver, Kidney and/or Pancreas April 2003 August 27, 2018
NCT02699736 Enrolling by invitation EuroSIDA - Clinical and Virological Outcome of European Patients Infected With HIV January 1994 December 2030
NCT05147935 Enrolling by invitation N/A Adding Specialist Palliative Care to Transplantation Pilot Trial March 31, 2022 March 2024
NCT06062706 Enrolling by invitation Robotic vs. Laparoscopic vs. Open Living Donor Hepatectomy August 6, 2023 October 30, 2023
NCT04592744 Enrolling by invitation Phase 4 Angiotensin 2 for AKI After OLT April 8, 2022 December 2024
NCT06069050 Not yet recruiting N/A SALT in Adolescents With End-stage Liver Disease October 20, 2023 March 30, 2027
NCT06455280 Not yet recruiting Phase 1 SIPLIZUMAB in AILD and LT June 1, 2024 March 31, 2026
NCT03946852 Not yet recruiting N/A Abdominal Regional Perfusion in Donation After Cardiac Death for Multi-Organ Transplantation June 2019 June 2026
NCT05205954 Not yet recruiting N/A HepHospital: A Hepatology Home Hospital Intervention for Patients With Advanced Liver Disease March 1, 2024 December 30, 2025
NCT03803423 Recruiting N/A Dissemination of the Donor Application: Utilizing Social Media to Identify Potential Live Organ Donors November 27, 2017 November 27, 2024
NCT02581085 Recruiting Phase 2 Tocotrienol Against the Progression of End Stage Liver Disease November 1, 2019 December 31, 2028
NCT03228290 Recruiting Functional Assessment in Liver Transplantation October 12, 2011 December 31, 2028
NCT03266575 Recruiting N/A Pulmonary Rehabilitation in End-Stage Liver Disease February 1, 2018 December 2026
NCT03540771 Recruiting N/A Introducing Palliative Care (PC) Within the Treatment of End Stage Liver Disease (ESLD) January 30, 2019 May 31, 2025
NCT03870568 Recruiting Functional Assessment in Liver Transplantation October 6, 2015 December 2025
NCT04037995 Recruiting Real World Study of End-stage Liver Disease in China September 1, 2019 September 1, 2029
NCT04107883 Recruiting N/A Effect of Transfusion of Plasma on Endothelial During Liver Transplantation October 1, 2023 December 31, 2024
NCT04496479 Recruiting Phase 2 Allogenic Hepatocyte Transplantation Into Periduodenal Lymph Nodes March 11, 2022 August 7, 2026
NCT04744389 Recruiting N/A Comparison of Hypothermic Versus Normothermic Ex-vivo Preservation. December 15, 2020 March 31, 2023
NCT05253287 Recruiting Phase 2/Phase 3 Growth Hormone in Decompensated Liver Cirrhosis February 1, 2022 January 2025
NCT05260268 Recruiting N/A Technology Enabled Strategies to Promote Treatment Adherence in Liver Transplant December 1, 2022 January 1, 2027
NCT05457114 Recruiting Association Between the Use of Pulmonary Artery Catheter and Clinical Outcomes After Liver Transplantation May 1, 2022 December 31, 2022
NCT05477277 Recruiting N/A Adverse Outcomes and Mortality in Liver Transplant November 2, 2022 July 2024
NCT05981196 Recruiting Disparities Among Liver Transplant Patients November 15, 2023 December 2024
NCT05998330 Recruiting N/A LiverPAL: A Trial of Inpatient Palliative Care for Patients With Advanced Liver Disease September 20, 2023 July 2027
NCT06136221 Recruiting N/A Testing LiverWatch, a Home-Based Remote-Monitoring Intervention for Advanced Liver Disease May 1, 2024 May 31, 2026
NCT06173947 Recruiting SSM Predicts Outcomes of CLD Inpatients With Acute Liver Injury January 1, 2024 September 30, 2025
NCT06181474 Recruiting MELD ESAS Evolution: Assessment of the Symptomatic Burden of Patients With Advanced Chronic Liver Disease January 1, 2024 January 2025
NCT06382740 Recruiting Selection Protocol for Liver Transplantation in Patients Aged Over 70 Years October 1, 2022 October 1, 2025
NCT06418165 Recruiting Vienna Hypothermic Oxygenated Machine Perfusion Study January 1, 2018 December 31, 2038
NCT01148550 Suspended Longitudinal Study of Mitochondrial Hepatopathies August 18, 2010 May 2029
NCT02447926 Terminated N/A Procurement of Leukapheresis Products From End Stage Liver Disease (ESLD) Patients for Immunological Studies July 2014 July 2016
NCT01760356 Terminated Study of PD/PK/PG Relationships of Tacrolimus and Cyclosporin in Liver Transplant Patients May 1, 2011 May 17, 2021
NCT03534141 Terminated N/A Mild Hypothermia and Acute Kidney Injury in Liver Transplantation July 7, 2018 September 14, 2023
NCT03694431 Terminated N/A Comparative Trial of Home-Based Palliative Care January 7, 2019 January 24, 2020
NCT03208127 Terminated Phase 4 DAA Treatment in Donor HCV-positive to Recipient HCV-negative Liver Transplant November 21, 2017 June 4, 2021
NCT01412593 Unknown status Phase 1/Phase 2 Intra-hepatic Artery Bone Marrow Derived Stem Cells Infusion for the Treatment of Advanced Liver Cirrhosis September 2011 September 2013
NCT03363451 Unknown status A Study on Diagnosis and Treatment of End Stage Liver Disease Complicated With Infection (SESLDIR Study) February 1, 2018 December 31, 2018
NCT03362632 Unknown status A Study on Diagnosis and Treatment of End Stage Liver Disease Complicated With Infection (SESLDIP Study) July 1, 2018 June 30, 2019
NCT03633812 Unknown status Effect of Preoperative Beta Blocker Use Postoperative Renal Function in the Patients Undergoing Liver Transplantation October 28, 2016 December 31, 2020
NCT02148562 Unknown status Assessment of Hepatitis B Virus Intra-host Population and Host-specific Immune Marker Diversity April 2014 December 2017
NCT01728727 Unknown status Phase 1/Phase 2 Safety and Efficacy of Human Umbilical Cord Derived Mesenchymal Stem Cells for Treatment of HBV-related Liver Cirrhosis September 2012 September 2015
NCT01728688 Unknown status Phase 1/Phase 2 Safety and Efficacy of Human Autologous Peripheral Blood Stem Cells for Treatment of HBV-related Liver Cirrhosis September 2012 September 2015
NCT01724697 Unknown status Phase 1/Phase 2 Safety and Efficacy of Human Bone Marrow Stem Cells for Treatment of HBV-related Liver Cirrhosis September 2012 September 2015
NCT01711073 Unknown status Phase 1 Mobilization of Stem Cells With G-CSF and Mozobil in Patients With End Stage Liver Disease October 2012 September 2013
NCT01434056 Unknown status Prediction of Mortality in Patients Waiting for Liver Transplantation Through Brain Magnetic Resonance Imaging November 2011 February 2015
NCT05386953 Unknown status Intraoperative Normal Saline Administration and Acute Kidney Injury in Patients Undergoing Liver Transplantation April 1, 2022 December 31, 2022
NCT02889094 Unknown status French HIV-HBV Cohort October 2016 September 2018
NCT01350167 Unknown status N/A Screening for Liver Cancer With CT vs. Ultrasound in Patients With Advanced Liver Disease November 2001 December 2021
NCT03109236 Unknown status Phase 3 Autologous Endothelial Progenitor Cell Therapy for Reversal of Liver Cirrhosis August 24, 2017 December 31, 2023
NCT01171742 Unknown status Phase 3 Effect of Intermittent Hepatic Inflow Occlusion During Donor Hepatectomy In Living Donor Liver Transplantation July 2008 August 2010
NCT04107428 Unknown status Phase 4 Somatostatin in Living Donor Liver Transplantation December 2019 February 2022
NCT03468140 Withdrawn Early Phase 1 Pilot Trial of Eculizumab Therapy to Reduce Preservation Injury in Human Macrosteatotic Liver Transplantation October 1, 2021 December 31, 2023
NCT01331785 Withdrawn N/A Mechanism and the Effect of Midodrine on Portal Pressures in Patients With Cirrhosis April 2011 July 2012
NCT01794637 Withdrawn Study of Peripheral Tissue Oxygenation in End-stage Liver Disease Patients During Liver Transplantation February 2013 March 2016
MedGen concept unique identifier (MedGen Concept name)
C0745744
MedGen unique identifier (MedGen Concept name)
148174
MeSH unique ID (MeSH (Medical Subject Headings))
D058625