Annotation Detail

Information
Associated Genes
CYP2B6
Associated Variants
CYP2B6 MUTATION
CYP2B6 MUTATION
Associated Disease
ICHTHYOSIS, LAMELLAR, 3
Source Database
DisGeNET
Description
The pathogenesis of Kava dermopathy may be associated with a functional defect in one or more cytochrome P450 enzymes implicated in epidermal integrity, thus mimicking the genetic defect as seen in lamellar ichthyosis type 3.
Pubmed
25069767
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
4
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Drugs