chr10:6052652:> Detail (hg19)
Information
Genome
Assembly | Position |
---|---|
hg19 | chr10:6,052,652-6,104,330 |
hg38 | chr10:6,010,689-6,062,367 |
HGVS
Type | Transcript | Protein |
---|---|---|
Summary
MGeND
Clinical significance | |
Variant entry | |
GWAS entry | |
Disease area statistics | Show details |
Frequency
[No Data.]
Prediction
[No Data.]
ClinVar
Clinical Significance | |
Review star | [No Data.] |
Show details |
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
Score | Disease name | Description | Source | Pubmed | Links |
---|---|---|---|---|---|
0.003 | squamous cell carcinoma | NA | BeFree,LHGDN | Detail | |
<0.001 | Cardiomyopathy, Dilated | NA | BeFree | Detail | |
<0.001 | celiac disease | NA | BeFree | Detail | |
<0.001 | Chest Pain | NA | BeFree | Detail | |
<0.001 | Primary biliary cirrhosis | NA | BeFree | Detail | |
<0.001 | Cholangitis, Sclerosing | NA | BeFree | Detail | |
0.002 | chorioamnionitis | NA | GAD | Detail | |
0.001 | colitis | NA | BeFree | Detail | |
<0.001 | ulcerative colitis | NA | BeFree | Detail | |
<0.001 | common variable immunodeficiency | NA | BeFree | Detail | |
0.002 | Connective Tissue Diseases | NA | GAD | Detail | |
0.246 | Crohn Disease | NA | BeFree,CTD_human,GAD,GWASCAT | Detail | |
<0.001 | Dengue Fever | NA | BeFree | Detail | |
<0.001 | dermatitis | NA | BeFree | Detail | |
<0.001 | Dermatitis, Atopic | NA | BeFree | Detail | |
<0.001 | dermatomyositis | NA | BeFree | Detail | |
0.002 | Diabetes | NA | BeFree | Detail | |
0.084 | diabetes mellitus | NA | BeFree,GAD,RGD | Detail | |
0.080 | Diabetes Mellitus, Experimental | NA | RGD | Detail | |
0.006 | Diabetes Mellitus, Non-Insulin-Dependent | NA | BeFree,GAD | Detail | |
<0.001 | diphtheria | NA | BeFree | Detail | |
0.003 | Down syndrome | NA | BeFree,LHGDN | Detail | |
<0.001 | duodenal ulcer | NA | BeFree | Detail | |
<0.001 | Eczema | NA | BeFree | Detail | |
0.081 | Experimental Autoimmune Encephalomyelitis | NA | BeFree,RGD | Detail | |
0.003 | Eosinophilia | NA | BeFree,LHGDN | Detail | |
0.002 | Fetal Diseases | NA | GAD | Detail | |
0.002 | Fetal Membranes, Premature Rupture | NA | GAD | Detail | |
<0.001 | Gastritis, Atrophic | NA | BeFree | Detail | |
<0.001 | Gingival Diseases | NA | BeFree | Detail | |
<0.001 | gingivitis | NA | BeFree | Detail | |
<0.001 | glioblastoma | NA | BeFree | Detail | |
<0.001 | Glioma | NA | BeFree | Detail | |
0.120 | glomerulonephritis | NA | CTD_human | Detail | |
0.011 | Graft-vs-Host Disease | For this purpose, adoptively transferred CD4+CD25+ Tregs from gzmA-/- mice were ... | BeFree,LHGDN | 25928296 | Detail |
0.005 | Graves Disease | NA | BeFree,GAD | Detail | |
<0.001 | Guillain-Barre syndrome | NA | BeFree | Detail | |
0.003 | Head and Neck Neoplasms | NA | LHGDN | Detail | |
<0.001 | congestive heart failure | NA | BeFree | Detail | |
0.003 | hemolytic-uremic syndrome | NA | LHGDN | Detail | |
<0.001 | Hemophilia A | NA | BeFree | Detail | |
<0.001 | Hemorrhagic Fever with Renal Syndrome | NA | BeFree | Detail | |
0.003 | hepatitis A | NA | LHGDN | Detail | |
0.001 | hepatitis B | NA | BeFree | Detail | |
<0.001 | Herpes NOS | NA | BeFree | Detail | |
0.132 | HIV Infections | In the liver, regulatory CD4(+) CD25(+) Foxp3(+) T cells, as well as CD4(+) CD25... | BeFree,CTD_human,GAD,LHGDN | 25174689 | Detail |
0.002 | Hyperparathyroidism, Secondary | NA | GAD | Detail | |
<0.001 | hypothyroidism | NA | BeFree | Detail | |
<0.001 | Immune System Diseases | NA | BeFree | Detail | |
0.007 | Inflammation | NA | GAD | Detail | |
0.124 | Inflammatory Bowel Diseases | NA | BeFree,GAD,GWASCAT | Detail | |
0.001 | Autoimmune thyroid disease | We genotyped the five SNPs (rs12760457, rs2797415, rs1310182, rs2476599, and rs3... | BeFree | 20615141 | Detail |
<0.001 | thyroiditis | We genotyped the five SNPs (rs12760457, rs2797415, rs1310182, rs2476599, and rs3... | BeFree | 20615141 | Detail |
<0.001 | irritable bowel syndrome | NA | BeFree | Detail | |
<0.001 | arthropathy | NA | BeFree | Detail | |
<0.001 | Kidney Failure, Chronic | NA | BeFree | Detail | |
0.002 | Premature Obstetric Labor | NA | GAD | Detail | |
<0.001 | Lambert-Eaton myasthenic syndrome | NA | BeFree | Detail | |
<0.001 | Leishmaniasis, Cutaneous | IL2RA genetic variants reduce IL-2-dependent responses and aggravate human cutan... | BeFree | 25672756 | Detail |
0.003 | Leishmaniasis, Visceral | NA | BeFree,LHGDN | Detail | |
<0.001 | leprosy | NA | BeFree | Detail | |
0.005 | leukemia | NA | BeFree,LHGDN | Detail | |
0.002 | chronic lymphocytic leukemia | NA | BeFree | Detail | |
0.001 | hairy cell leukemia | NA | BeFree | Detail | |
0.003 | lymphoid leukemia | NA | BeFree,LHGDN | Detail | |
0.003 | Leukemia, Myelocytic, Acute | We herein report a case of AML accompanied by thoracic epidural MS with a high C... | BeFree | 24881741 | Detail |
<0.001 | myeloid leukemia | NA | BeFree | Detail | |
0.002 | Myeloid Leukemia, Chronic | NA | BeFree | Detail | |
0.005 | Leukemia, T-Cell | NA | BeFree | Detail | |
0.008 | Adult T-Cell Lymphoma/Leukemia | Adult T-cell leukemia/lymphoma (ATL) is an aggressive malignancy of CD4+CD25+ ly... | BeFree | 24890041 | Detail |
<0.001 | Lung diseases | NA | BeFree | Detail | |
<0.001 | Lupus Vulgaris | NA | BeFree | Detail | |
0.003 | Lupus Erythematosus, Cutaneous | NA | LHGDN | Detail | |
<0.001 | Lupus Erythematosus, Discoid | NA | BeFree | Detail | |
0.012 | Lupus Erythematosus, Systemic | Expression of Ets-1 and FOXP3 mRNA in CD4(+)CD25 (+) T regulatory cells from pat... | BeFree,GAD,LHGDN | 24221578 | Detail |
0.012 | Lupus Erythematosus, Systemic | FoxP3(+) cells were depleted within CD4(+)CD25(+) Tregs in patients with APS (28... | BeFree,GAD,LHGDN | 25862984 | Detail |
<0.001 | lymphocytic choriomeningitis | NA | BeFree | Detail | |
0.002 | lymphoma | NA | BeFree | Detail | |
<0.001 | Lymphoma, Follicular | NA | BeFree | Detail | |
0.005 | Lymphoma, Non-Hodgkin | NA | LHGDN | Detail | |
<0.001 | Lymphoproliferative Disorders | NA | BeFree | Detail | |
<0.001 | Waldenstrom Macroglobulinemia | Interestingly, the transcriptome of the Waldenström B-cell clone was highly diff... | BeFree | 25655603 | Detail |
<0.001 | malaria | NA | BeFree | Detail | |
0.002 | mastocytosis | Formalin-fixed specimens of 35 patients with vulvodynia were evaluated immunohis... | BeFree | 25912132 | Detail |
0.003 | measles | NA | BeFree,GAD | Detail | |
0.005 | melanoma | NA | BeFree,GAD | Detail | |
0.004 | mitral valve stenosis | NA | BeFree,LHGDN | Detail | |
<0.001 | Monoclonal Gammopathy of Undetermined Significance | NA | BeFree | Detail | |
<0.001 | Mucocutaneous Lymph Node Syndrome | NA | BeFree | Detail | |
<0.001 | multiple myeloma | NA | BeFree | Detail | |
0.303 | multiple sclerosis | Multiple sclerosis-associated IL2RA polymorphism controls GM-CSF production in h... | BeFree,CTD_human,GAD,GWASCAT,LHGDN | 25278028 | Detail |
0.303 | multiple sclerosis | Associations of CLEC16A and IL2RA with MS were validated. | BeFree,CTD_human,GAD,GWASCAT,LHGDN | 25903733 | Detail |
0.003 | mumps | NA | BeFree,GAD | Detail | |
0.002 | Musculoskeletal Diseases | NA | GAD | Detail | |
0.002 | myasthenia gravis | NA | BeFree | Detail | |
<0.001 | Mycoses | NA | BeFree | Detail | |
<0.001 | myocarditis | NA | BeFree | Detail | |
<0.001 | nervous system disorder | NA | BeFree | Detail | |
<0.001 | neuroblastoma | NA | BeFree | Detail | |
0.001 | ovarian carcinoma | NA | BeFree | Detail | |
<0.001 | Pustulosis of Palms and Soles | NA | BeFree | Detail | |
0.003 | pancreatitis | NA | LHGDN | Detail | |
<0.001 | papilloma | NA | BeFree | Detail | |
<0.001 | tropical spastic paraparesis | NA | BeFree | Detail | |
<0.001 | paraplegia | We herein report a case of AML accompanied by thoracic epidural MS with a high C... | BeFree | 24881741 | Detail |
<0.001 | bullous pemphigoid | NA | BeFree | Detail | |
<0.001 | Periodontal Diseases | NA | BeFree | Detail | |
0.004 | periodontitis | However, the roles of other genes, such as CSF3 (colony stimulating factor 3 rec... | BeFree,LHGDN | 24476546 | Detail |
<0.001 | Pleural effusion disorder | NA | BeFree | Detail | |
<0.001 | polymyalgia rheumatica | NA | BeFree | Detail | |
0.002 | pre-eclampsia | NA | GAD | Detail | |
<0.001 | Precancerous Conditions | NA | BeFree | Detail | |
0.002 | Pregnancy Complications, Hematologic | NA | GAD | Detail | |
<0.001 | Prostatic Neoplasms | NA | BeFree | Detail | |
<0.001 | psoriasis | NA | BeFree | Detail | |
<0.001 | pulmonary fibrosis | NA | BeFree | Detail | |
<0.001 | kidney failure | NA | BeFree | Detail | |
0.002 | Respiratory Syncytial Virus Infections | NA | GAD | Detail | |
<0.001 | Retroviridae Infections | NA | BeFree | Detail | |
<0.001 | rhinitis | NA | BeFree | Detail | |
0.003 | rubella | NA | BeFree,GAD | Detail | |
<0.001 | sarcoidosis | NA | BeFree | Detail | |
0.120 | schizophrenia | NA | BeFree,CTD_human | Detail | |
<0.001 | systemic scleroderma | NA | BeFree | Detail | |
<0.001 | Septicemia | An increase in CD3+CD4+CD25+ regulatory T cells after administration of umbilica... | BeFree | 25337817 | Detail |
0.003 | Dermatologic disorders | NA | BeFree,GAD | Detail | |
<0.001 | ankylosing spondylitis | This study suggests that FoxO1, but not miR-27a, miR-182, and IL2RA, contributes... | BeFree | 25414190 | Detail |
0.003 | Giant Cell Arteritis | NA | BeFree,GAD | Detail | |
<0.001 | thymoma | NA | BeFree | Detail | |
<0.001 | Thymus Hyperplasia | NA | BeFree | Detail | |
0.005 | Thyroid Diseases | NA | GAD,LHGDN | Detail | |
<0.001 | thyroiditis | NA | BeFree | Detail | |
<0.001 | Trisomy | NA | BeFree | Detail | |
<0.001 | Chagas disease | Increase in the expression of CD4 + CD25+ lymphocytic T cells in the indetermina... | BeFree | 25205548 | Detail |
0.001 | tuberculosis | These findings indicated that CD4+ CD25+ FOXP3+ Treg cells may have a primary ro... | BeFree | 25483347 | Detail |
<0.001 | pleural tuberculosis | NA | BeFree | Detail | |
<0.001 | Tuberculosis, Pulmonary | NA | BeFree | Detail | |
<0.001 | Unipolar Depression | NA | BeFree | Detail | |
<0.001 | urticaria | NA | BeFree | Detail | |
0.004 | urticaria pigmentosa | Formalin-fixed specimens of 35 patients with vulvodynia were evaluated immunohis... | BeFree,LHGDN | 25912132 | Detail |
<0.001 | Uveitis, Intermediate | NA | BeFree | Detail | |
0.002 | vasculitis | NA | GAD | Detail | |
<0.001 | Virus Diseases | NA | BeFree | Detail | |
0.122 | vitiligo | NA | GAD,GWASCAT | Detail | |
<0.001 | Wheezing | NA | BeFree | Detail | |
<0.001 | B-Cell Lymphomas | NA | BeFree | Detail | |
0.006 | T-Cell Lymphoma | NA | BeFree,LHGDN | Detail | |
<0.001 | Lymphoma, T-Cell, Cutaneous | NA | BeFree | Detail | |
<0.001 | Pleural Effusion, Malignant | NA | BeFree | Detail | |
0.001 | severe combined immunodeficiency | NA | BeFree | Detail | |
<0.001 | Polyendocrinopathies, Autoimmune | FoxP3(+) cells were depleted within CD4(+)CD25(+) Tregs in patients with APS (28... | BeFree | 25862984 | Detail |
<0.001 | Arthritis, Reactive | NA | BeFree | Detail | |
<0.001 | polymyositis | NA | BeFree | Detail | |
<0.001 | Acute appendicitis NOS (disorder) | NA | BeFree | Detail | |
<0.001 | Pancreatitis, Chronic | NA | BeFree | Detail | |
<0.001 | Epstein-Barr Virus Infections | NA | BeFree | Detail | |
<0.001 | Small cell carcinoma of lung | NA | BeFree | Detail | |
<0.001 | Active tuberculosis | NA | BeFree | Detail | |
<0.001 | Atrophic condition of skin | NA | BeFree | Detail | |
0.009 | Premature Birth | NA | GAD | Detail | |
<0.001 | Cutaneous Melanoma | NA | BeFree | Detail | |
<0.001 | Granulocytic Sarcoma | Acute myeloid leukemia concurrent with spinal epidural extramedullary myeloid sa... | BeFree | 24881741 | Detail |
<0.001 | Non-arthropod borne lymphocytic choriomeningitis | NA | BeFree | Detail | |
<0.001 | allergic asthma | Our data suggest that IL-35 can effectively suppress the proliferation and IL-4 ... | BeFree | 26044961 | Detail |
0.120 | Dermatitis, Allergic Contact | NA | CTD_human | Detail | |
<0.001 | Hypopigmentation disorder | NA | BeFree | Detail | |
<0.001 | Aortic Aneurysm, Abdominal | NA | BeFree | Detail | |
0.001 | Autoimmune thyroid disease | Polymorphisms in thyroid genes (TG, TSHR) and immunoregulatory genes (HLA, CTLA4... | BeFree | 25231450 | Detail |
<0.001 | Tumor Progression | NA | BeFree | Detail | |
<0.001 | Diabetes, Autoimmune | NA | BeFree | Detail | |
<0.001 | Pneumonia, Interstitial | NA | BeFree | Detail | |
<0.001 | Ki-1+ Anaplastic Large Cell Lymphoma | NA | BeFree | Detail | |
<0.001 | Adult type dermatomyositis | NA | BeFree | Detail | |
<0.001 | granulomatous hepatitis | NA | BeFree | Detail | |
<0.001 | pancreatic carcinoma | NA | BeFree | Detail | |
<0.001 | Gastrointestinal Stromal Tumors | NA | BeFree | Detail | |
<0.001 | Papillary thyroid carcinoma | This phenotypic change was associated with increased T-cell activation (%CD25(+)... | BeFree | 25294906 | Detail |
<0.001 | Fibrosis, Liver | NA | BeFree | Detail | |
0.001 | Hepatitis, Autoimmune | NA | BeFree | Detail | |
<0.001 | Malignant neoplasm of lung | NA | BeFree | Detail | |
<0.001 | age related macular degeneration | NA | BeFree | Detail | |
0.002 | Disease Progression | NA | GAD | Detail | |
<0.001 | Sepsis | An increase in CD3+CD4+CD25+ regulatory T cells after administration of umbilica... | BeFree | 25337817 | Detail |
<0.001 | Psoriasis vulgaris | NA | BeFree | Detail | |
0.003 | Chronic Periodontitis | NA | LHGDN | Detail | |
<0.001 | Acquired aplastic anemia | NA | BeFree | Detail | |
<0.001 | Hyperimmunoglobulin M syndrome | NA | BeFree | Detail | |
<0.001 | gastric adenocarcinoma | NA | BeFree | Detail | |
<0.001 | Squamous cell carcinoma of esophagus | NA | BeFree | Detail | |
<0.001 | Solid tumour | NA | BeFree | Detail | |
<0.001 | Acute Undifferentiated Leukemia | NA | BeFree | Detail | |
<0.001 | Adenocarcinoma of pancreas | NA | BeFree | Detail | |
<0.001 | Superficial ulcer | NA | BeFree | Detail | |
<0.001 | Stable angina | NA | BeFree | Detail | |
<0.001 | Malonic aciduria | NA | BeFree | Detail | |
<0.001 | Asymptomatic human immunodeficiency virus infection | NA | BeFree | Detail | |
<0.001 | Malignant neoplasm of pancreas | NA | BeFree | Detail | |
<0.001 | Splenic Marginal Zone B-Cell Lymphoma | NA | BeFree | Detail | |
<0.001 | Hairy cell leukemia variant | NA | BeFree | Detail | |
0.003 | prediabetes syndrome | NA | BeFree,GAD | Detail | |
<0.001 | Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site | Hp GE-driven enhancement of lymphocyte cytotoxic activity was associated with th... | BeFree | 24448078 | Detail |
<0.001 | Malignant neoplasm of prostate | NA | BeFree | Detail | |
<0.001 | Polyradiculoneuropathy, Chronic Inflammatory Demyelinating | NA | BeFree | Detail | |
<0.001 | Immune thrombocytopenic purpura | NA | BeFree | Detail | |
<0.001 | Hyper-IgM Immunodeficiency Syndrome, Type 1 | NA | BeFree | Detail | |
<0.001 | lupus erythematosus | NA | BeFree | Detail | |
<0.001 | Developmental delay (disorder) | NA | BeFree | Detail | |
<0.001 | Ichthyosis bullosa of Siemens | NA | BeFree | Detail | |
<0.001 | pricking of skin | NA | BeFree | Detail | |
0.001 | Hepatitis B, Chronic | NA | BeFree | Detail | |
<0.001 | Hepatitis C, Chronic | NA | BeFree | Detail | |
<0.001 | Atherosclerotic occlusive disease | NA | BeFree | Detail | |
0.001 | primary sclerosing cholangitis | Reduced FOXP3(+) regulatory T cells in patients with primary sclerosing cholangi... | BeFree | 24412607 | Detail |
<0.001 | Chronic idiopathic urticaria | NA | BeFree | Detail | |
<0.001 | Carcinogenesis | NA | BeFree | Detail | |
<0.001 | Leukemogenesis | NA | BeFree | Detail | |
<0.001 | prostate carcinoma | NA | BeFree | Detail | |
<0.001 | Hashimoto Disease | NA | BeFree | Detail | |
0.001 | Epithelial ovarian cancer | NA | BeFree | Detail | |
0.001 | breast carcinoma | NA | BeFree | Detail | |
<0.001 | Carcinoma of lung | NA | BeFree | Detail | |
<0.001 | Central neuroblastoma | NA | BeFree | Detail | |
<0.001 | Acute anterior uveitis | This study suggests that FoxO1, but not miR-27a, miR-182, and IL2RA, contributes... | BeFree | 25414190 | Detail |
<0.001 | Dissecting aneurysm of the thoracic aorta | We herein report a case of AML accompanied by thoracic epidural MS with a high C... | BeFree | 24881741 | Detail |
<0.001 | Malignant neoplasm of kidney | NA | BeFree | Detail | |
<0.001 | allergic symptom | NA | BeFree | Detail | |
<0.001 | Hypereosinophilia | NA | BeFree | Detail | |
<0.001 | adult acute lymphocytic leukemia | NA | BeFree | Detail | |
<0.001 | Multiple Sclerosis, Secondary Progressive | NA | BeFree | Detail | |
<0.001 | Multiple Sclerosis, Relapsing-Remitting | NA | BeFree | Detail | |
0.080 | Myasthenia Gravis, Autoimmune, Experimental | NA | RGD | Detail | |
<0.001 | malignant pleural mesothelioma | NA | BeFree | Detail | |
<0.001 | Helicobacter pylori infection | NA | BeFree | Detail | |
0.001 | Acute GVH disease | NA | BeFree | Detail | |
<0.001 | Mycosis fungoides/Sezary syndrome NOS | NA | BeFree | Detail | |
<0.001 | Chronic graft-versus-host disease | NA | BeFree | Detail | |
<0.001 | Cardiomyopathies | NA | BeFree | Detail | |
<0.001 | autoimmune thyroiditis | NA | BeFree | Detail | |
<0.001 | Acute coronary syndrome | Changes of naturally occurring CD4(+)CD25(+) FOXP3(+) regulatory T cells in pati... | BeFree | 25740578 | Detail |
<0.001 | Arthritis, Collagen-Induced | NA | BeFree | Detail | |
0.080 | Arthritis, Experimental | NA | RGD | Detail | |
<0.001 | Gastric infection | NA | BeFree | Detail | |
<0.001 | cutaneous mastocytosis | NA | BeFree | Detail | |
0.001 | Malignant neoplasm of ovary | NA | BeFree | Detail | |
<0.001 | Primary HIV infection | NA | BeFree | Detail | |
<0.001 | Squamous cell carcinoma of the head and neck | NA | BeFree | Detail | |
<0.001 | major depressive disorder | NA | BeFree | Detail | |
<0.001 | Deficiency of vitamin D3 | NA | BeFree | Detail | |
<0.001 | Follicular bronchiolitis | NA | BeFree | Detail | |
0.001 | Precursor B-cell lymphoblastic leukemia | Expression of CD25 is a specific and relatively sensitive marker for the Philade... | BeFree | 25337274 | Detail |
<0.001 | Eosinophilic disorder | NA | BeFree | Detail | |
<0.001 | autoimmune lymphoproliferative syndrome | NA | BeFree | Detail | |
<0.001 | Gastric Mucosa-Associated Lymphoid Tissue Lymphoma | NA | BeFree | Detail | |
<0.001 | Undifferentiated leukemia | NA | BeFree | Detail | |
<0.001 | renal carcinoma | NA | BeFree | Detail | |
<0.001 | alpha^+^ Thalassemia | Hb Cibeles [α2 CD25(B6) (Gly → Asp)]: a novel alpha chain variant causing alpha-... | BeFree | 25212678 | Detail |
0.006 | Mammary Neoplasms | NA | BeFree,LHGDN | Detail | |
<0.001 | Salivary Gland Pleomorphic Adenoma | NA | BeFree | Detail | |
<0.001 | Tumor Immunity | NA | BeFree | Detail | |
<0.001 | Xenograft Model | NA | BeFree | Detail | |
<0.001 | Leukemia, Large Granular Lymphocytic | NA | BeFree | Detail | |
0.003 | Sjogren's syndrome | NA | LHGDN | Detail | |
<0.001 | Renal Insufficiency | NA | BeFree | Detail | |
<0.001 | Latent Tuberculosis | The mRNA levels of FOXP3 and the proportion of circulating CD4+ CD25+ FOXP3+ Tre... | BeFree | 25483347 | Detail |
<0.001 | Macular dystrophy, corneal type 1 | NA | BeFree | Detail | |
<0.001 | Disorder characterized by eosinophilia | NA | BeFree | Detail | |
<0.001 | Histiocytic medullary reticulosis (disorder) | NA | BeFree | Detail | |
<0.001 | IMMUNE SUPPRESSION | NA | BeFree | Detail | |
<0.001 | Amyotrophic Lateral Sclerosis, Sporadic | NA | BeFree | Detail | |
0.120 | DIABETES MELLITUS, INSULIN-DEPENDENT, 10 | NA | CTD_human | Detail | |
0.002 | temporal arteritis | NA | GAD | Detail | |
<0.001 | Latent autoimmune diabetes mellitus in adult | NA | BeFree | Detail | |
<0.001 | Philadelphia chromosome-positive acute lymphoblastic leukemia | NA | BeFree | Detail | |
<0.001 | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma | NA | BeFree | Detail | |
0.005 | Precursor Cell Lymphoblastic Leukemia Lymphoma | NA | BeFree,GAD,LHGDN | Detail | |
0.004 | liver carcinoma | This study provides evidence of demethylation of TSDR, increased gene expression... | BeFree,LHGDN | 25907075 | Detail |
<0.001 | Chronic kidney disease stage 5 | NA | BeFree | Detail | |
<0.001 | T-cell prolymphocytic leukemia | NA | BeFree | Detail | |
0.001 | Allergic rhinitis (disorder) | NA | BeFree | Detail | |
0.002 | Infection of amniotic sac and membranes, unspecified, unspecified trimester, not applicable or unspecified | NA | GAD | Detail | |
<0.001 | Acute malaria | NA | BeFree | Detail | |
<0.001 | Nasopharyngeal carcinoma | NA | BeFree | Detail | |
<0.001 | Nonalcoholic Steatohepatitis | NA | BeFree | Detail | |
0.007 | Juvenile arthritis | NA | BeFree,GAD,LHGDN | Detail | |
0.001 | Allergic disposition | NA | BeFree | Detail | |
0.005 | Infection | NA | GAD,LHGDN | Detail | |
0.002 | juvenile rheumatoid arthritis | NA | BeFree | Detail | |
<0.001 | Experimental Organism Basal Cell Carcinoma | NA | BeFree | Detail | |
0.002 | Addison Disease | NA | GAD | Detail | |
0.243 | alopecia areata | NA | BeFree,CTD_human,GAD,GWASCAT | Detail | |
<0.001 | alpha-Thalassemia | Hb Cibeles [α2 CD25(B6) (Gly → Asp)]: a novel alpha chain variant causing alpha-... | BeFree | 25212678 | Detail |
<0.001 | aortic aneurysm | NA | BeFree | Detail | |
<0.001 | arteriosclerosis | Interleukin (IL) -2 receptor subunit α regulates lymphocyte activation, which pl... | BeFree | 26293465 | Detail |
0.004 | arthritis | NA | BeFree,GAD | Detail | |
<0.001 | Arthritis, Psoriatic | NA | BeFree | Detail | |
0.257 | rheumatoid arthritis | In this study, we demonstrated that the frequencies of CD3(+) CD4(+) IL-17(+) Th... | BeFree,CTD_human,GAD,GWASCAT | 25164131 | Detail |
0.089 | asthma | CD4(+) CD25(+) CD127(-/low) T(regs) from participants without asthma did not eli... | BeFree,GAD,RGD | 25048599 | Detail |
<0.001 | atherosclerosis | Interleukin (IL) -2 receptor subunit α regulates lymphocyte activation, which pl... | BeFree | 26293465 | Detail |
0.002 | atrial fibrillation | NA | GAD | Detail | |
0.021 | Autoimmune Diseases | Genetic variants in il2 and il2ra have been associated with autoimmune disease s... | BeFree,GAD | 25725581 | Detail |
0.021 | Autoimmune Diseases | Recent research has demonstrated an increasing role of newly discovered cells su... | BeFree,GAD | 26000316 | Detail |
0.021 | Autoimmune Diseases | We identified 27 genome-wide significant loci associated with one or more pAIDs,... | BeFree,GAD | 26301688 | Detail |
<0.001 | Behcet Syndrome | No significant association of miR-27a, FoxO1, and IL2RA with BD or VKH was obser... | BeFree | 24801147 | Detail |
0.120 | berylliosis | NA | CTD_human | Detail | |
<0.001 | bipolar disorder | NA | BeFree | Detail | |
0.002 | Malignant neoplasm of breast | NA | BeFree | Detail | |
0.002 | Bronchiolitis, Viral | NA | GAD | Detail | |
<0.001 | Noninfiltrating Intraductal Carcinoma | The more aggressive DCIS-C1 (highly proliferative, basal-like, or ERBB2(+)) disp... | BeFree | 26249178 | Detail |
0.001 | Non-small cell lung carcinoma | NA | BeFree | Detail | |
<0.001 | renal cell carcinoma | NA | BeFree | Detail |
Annotation
Annotations
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NA | DisGeNET | Detail |
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For this purpose, adoptively transferred CD4+CD25+ Tregs from gzmA-/- mice were analyzed in comparis... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
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In the liver, regulatory CD4(+) CD25(+) Foxp3(+) T cells, as well as CD4(+) CD25(+) PD1(+) T cells, ... | DisGeNET | Detail |
NA | DisGeNET | Detail |
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We genotyped the five SNPs (rs12760457, rs2797415, rs1310182, rs2476599, and rs3789604) of the PTPN2... | DisGeNET | Detail |
We genotyped the five SNPs (rs12760457, rs2797415, rs1310182, rs2476599, and rs3789604) of the PTPN2... | DisGeNET | Detail |
NA | DisGeNET | Detail |
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IL2RA genetic variants reduce IL-2-dependent responses and aggravate human cutaneous leishmaniasis. | DisGeNET | Detail |
NA | DisGeNET | Detail |
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We herein report a case of AML accompanied by thoracic epidural MS with a high CD25 expression, the ... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Adult T-cell leukemia/lymphoma (ATL) is an aggressive malignancy of CD4+CD25+ lymphocytes caused by ... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
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Expression of Ets-1 and FOXP3 mRNA in CD4(+)CD25 (+) T regulatory cells from patients with systemic ... | DisGeNET | Detail |
FoxP3(+) cells were depleted within CD4(+)CD25(+) Tregs in patients with APS (28.4%) relative to tho... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
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Interestingly, the transcriptome of the Waldenström B-cell clone was highly different than that of n... | DisGeNET | Detail |
NA | DisGeNET | Detail |
Formalin-fixed specimens of 35 patients with vulvodynia were evaluated immunohistochemically with an... | DisGeNET | Detail |
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Multiple sclerosis-associated IL2RA polymorphism controls GM-CSF production in human TH cells. | DisGeNET | Detail |
Associations of CLEC16A and IL2RA with MS were validated. | DisGeNET | Detail |
NA | DisGeNET | Detail |
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We herein report a case of AML accompanied by thoracic epidural MS with a high CD25 expression, the ... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
However, the roles of other genes, such as CSF3 (colony stimulating factor 3 receptor), CD40, TNFSF1... | DisGeNET | Detail |
NA | DisGeNET | Detail |
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An increase in CD3+CD4+CD25+ regulatory T cells after administration of umbilical cord-derived mesen... | DisGeNET | Detail |
NA | DisGeNET | Detail |
This study suggests that FoxO1, but not miR-27a, miR-182, and IL2RA, contributes to the genetic susc... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
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NA | DisGeNET | Detail |
Increase in the expression of CD4 + CD25+ lymphocytic T cells in the indeterminate clinical form of ... | DisGeNET | Detail |
These findings indicated that CD4+ CD25+ FOXP3+ Treg cells may have a primary role in the failure of... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Formalin-fixed specimens of 35 patients with vulvodynia were evaluated immunohistochemically with an... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
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NA | DisGeNET | Detail |
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FoxP3(+) cells were depleted within CD4(+)CD25(+) Tregs in patients with APS (28.4%) relative to tho... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
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Acute myeloid leukemia concurrent with spinal epidural extramedullary myeloid sarcoma accompanied by... | DisGeNET | Detail |
NA | DisGeNET | Detail |
Our data suggest that IL-35 can effectively suppress the proliferation and IL-4 production of activa... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Polymorphisms in thyroid genes (TG, TSHR) and immunoregulatory genes (HLA, CTLA4, PTPN22, CD40, FCRL... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
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This phenotypic change was associated with increased T-cell activation (%CD25(+) of CD3(+)) and IL2 ... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
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An increase in CD3+CD4+CD25+ regulatory T cells after administration of umbilical cord-derived mesen... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
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Hp GE-driven enhancement of lymphocyte cytotoxic activity was associated with the expansion of CD3(-... | DisGeNET | Detail |
NA | DisGeNET | Detail |
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Reduced FOXP3(+) regulatory T cells in patients with primary sclerosing cholangitis are associated w... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
This study suggests that FoxO1, but not miR-27a, miR-182, and IL2RA, contributes to the genetic susc... | DisGeNET | Detail |
We herein report a case of AML accompanied by thoracic epidural MS with a high CD25 expression, the ... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
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NA | DisGeNET | Detail |
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Changes of naturally occurring CD4(+)CD25(+) FOXP3(+) regulatory T cells in patients with acute coro... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
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NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Expression of CD25 is a specific and relatively sensitive marker for the Philadelphia chromosome (BC... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Hb Cibeles [α2 CD25(B6) (Gly → Asp)]: a novel alpha chain variant causing alpha-thalassemia. | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
The mRNA levels of FOXP3 and the proportion of circulating CD4+ CD25+ FOXP3+ Treg cells were increas... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
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This study provides evidence of demethylation of TSDR, increased gene expression examined by lucifer... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
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NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Hb Cibeles [α2 CD25(B6) (Gly → Asp)]: a novel alpha chain variant causing alpha-thalassemia. | DisGeNET | Detail |
NA | DisGeNET | Detail |
Interleukin (IL) -2 receptor subunit α regulates lymphocyte activation, which plays an important rol... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
In this study, we demonstrated that the frequencies of CD3(+) CD4(+) IL-17(+) Th17 cells were signif... | DisGeNET | Detail |
CD4(+) CD25(+) CD127(-/low) T(regs) from participants without asthma did not elicit Ca(2+) influx in... | DisGeNET | Detail |
Interleukin (IL) -2 receptor subunit α regulates lymphocyte activation, which plays an important rol... | DisGeNET | Detail |
NA | DisGeNET | Detail |
Genetic variants in il2 and il2ra have been associated with autoimmune disease susceptibility in bot... | DisGeNET | Detail |
Recent research has demonstrated an increasing role of newly discovered cells such as Th17 (CD4+IL-1... | DisGeNET | Detail |
We identified 27 genome-wide significant loci associated with one or more pAIDs, mapping to in silic... | DisGeNET | Detail |
No significant association of miR-27a, FoxO1, and IL2RA with BD or VKH was observed. | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
The more aggressive DCIS-C1 (highly proliferative, basal-like, or ERBB2(+)) displayed signatures cha... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Overlapped Transcript Coordinates
Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
---|
Overlapped Transcript
Gene | Transcript ID | Chromosome | Start | Stop | Links |
---|
- Gene
- -
- dbSNP
- rs2797415 dbSNP
- Genome
- hg19
- Position
- chr10:6,052,652-6,104,330
- Variant Type
- snv
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