Annotation Detail
Information
- Associated Genes
- IL2RA
- Associated Variants
-
IL2RA MUTATION
IL2RA MUTATION - Associated Disease
- Autoimmune thyroid disease
- Source Database
- DisGeNET
- Description
- Polymorphisms in thyroid genes (TG, TSHR) and immunoregulatory genes (HLA, CTLA4, PTPN22, CD40, FCRL3, IL2RA, FOXP3) would contribute for about 70% to AITD, and environmental exposures (like iodine, smoking, infections, parity) for the remaining 30%.
- Pubmed
- 25231450
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 7
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00135720936040152
Drugs