Annotation Detail

Information
Associated Genes
IL2RA
Associated Variants
IL2RA MUTATION
IL2RA MUTATION
Associated Disease
Autoimmune Diseases
Source Database
DisGeNET
Description
We identified 27 genome-wide significant loci associated with one or more pAIDs, mapping to in silico-replicated autoimmune-associated genes (including IL2RA) and new candidate loci with established immunoregulatory functions such as ADGRL2, TENM3, ANKRD30A, ADCY7 and CD40LG.
Pubmed
26301688
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
3
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.0214115702859415
Drugs