Annotation Detail
Information
- Associated Genes
- IL2RA
- Associated Variants
-
IL2RA MUTATION
IL2RA MUTATION - Associated Disease
- Lupus Erythematosus, Systemic
- Source Database
- DisGeNET
- Description
- FoxP3(+) cells were depleted within CD4(+)CD25(+) Tregs in patients with APS (28.4%) relative to those without APS (46.3%, p = 0.008). mTOR activity was similar between SLE patients with and without APS.
- Pubmed
- 25862984
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 6
- Original source reporting the Gene Disease association
- BeFree,GAD,LHGDN
- DisGENET score for the Gene Disease association
- 0.0123443678971167
Drugs