chr10:133520406:> Detail (hg38)
Information
Genome
| Assembly | Position |
|---|---|
| hg19 | chr10:135,333,910-135,352,627 |
| hg38 | chr10:133,520,406-133,539,123 |
HGVS
| Type | Transcript | Protein |
|---|---|---|
Summary
MGeND
| Clinical significance | |
| Variant entry | |
| GWAS entry | |
| Disease area statistics | Show details |
Frequency
[No Data.]
Prediction
[No Data.]
ClinVar
| Clinical Significance | |
| Review star | [No Data.] |
| Show details | |
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
| Score | Disease name | Description | Source | Pubmed | Links |
|---|---|---|---|---|---|
| 0.044 | squamous cell carcinoma | When we examined the associations between several single-nucleotide polymorphism... | BeFree,GAD,LHGDN | 26125444 | Detail |
| <0.001 | Carcinoma, Transitional Cell | NA | BeFree | Detail | |
| <0.001 | Cardiomyopathy, Dilated | NA | BeFree | Detail | |
| <0.001 | Cardiovascular Diseases | NA | BeFree | Detail | |
| <0.001 | Malignant tumor of cervix | NA | BeFree | Detail | |
| 0.002 | Uterine Cervical Neoplasm | NA | GAD | Detail | |
| 0.007 | Chromosome Aberrations | NA | GAD | Detail | |
| 0.001 | Congenital chromosomal disease | NA | BeFree | Detail | |
| 0.002 | cleft lip | NA | GAD | Detail | |
| 0.002 | cleft palate | NA | GAD | Detail | |
| 0.004 | colorectal carcinoma | NA | BeFree | Detail | |
| 0.005 | Colorectal Neoplasms | NA | GAD,LHGDN | Detail | |
| <0.001 | Mental Depression | NA | BeFree | Detail | |
| 0.080 | depressive disorder | NA | BeFree,RGD | Detail | |
| 0.120 | Drug Eruptions | NA | CTD_human | Detail | |
| 0.001 | Diabetes | NA | BeFree | Detail | |
| 0.001 | diabetes mellitus | NA | BeFree | Detail | |
| 0.080 | Diabetes Mellitus, Experimental | NA | RGD | Detail | |
| <0.001 | Diabetes Mellitus, Insulin-Dependent | NA | BeFree | Detail | |
| 0.087 | Diabetes Mellitus, Non-Insulin-Dependent | NA | GAD,RGD | Detail | |
| 0.017 | DNA Damage | NA | GAD | Detail | |
| 0.002 | Pathological accumulation of air in tissues | NA | GAD | Detail | |
| 0.002 | endometriosis | NA | GAD | Detail | |
| <0.001 | Epithelial hyperplasia | NA | BeFree | Detail | |
| 0.029 | Esophageal Neoplasms | NA | BeFree,GAD | Detail | |
| <0.001 | Exanthema | NA | BeFree | Detail | |
| 0.206 | Fatty Liver | NA | BeFree,CTD_human,GAD,LHGDN,RGD | Detail | |
| 0.002 | Fetal Growth Retardation | NA | GAD | Detail | |
| 0.003 | Fibrosis | NA | LHGDN | Detail | |
| 0.005 | gastritis | NA | GAD | Detail | |
| <0.001 | Gastritis, Atrophic | NA | BeFree | Detail | |
| <0.001 | Glioma | NA | BeFree | Detail | |
| 0.017 | Head and Neck Neoplasms | NA | GAD | Detail | |
| <0.001 | Heart Diseases | NA | BeFree | Detail | |
| 0.120 | Cardiomegaly | NA | CTD_human | Detail | |
| <0.001 | Heart failure | NA | BeFree | Detail | |
| <0.001 | congestive heart failure | NA | BeFree | Detail | |
| 0.008 | hepatitis | NA | BeFree,GAD,LHGDN | Detail | |
| <0.001 | hepatitis A | NA | BeFree | Detail | |
| <0.001 | hepatitis B | The elucidation of a HBx-HNF4α-CYP2E1 pathway provides novel insight into the mo... | BeFree | 25238230 | Detail |
| 0.005 | Hepatitis, Toxic | NA | GAD | Detail | |
| 0.007 | hepatitis C | NA | BeFree,LHGDN | Detail | |
| 0.002 | HIV Infections | NA | GAD | Detail | |
| 0.007 | Hodgkin Disease | NA | GAD | Detail | |
| 0.002 | Hypertensive disease | NA | GAD | Detail | |
| 0.002 | Hypopharyngeal Neoplasms | NA | GAD | Detail | |
| 0.003 | ischemia | NA | LHGDN | Detail | |
| 0.002 | Kidney Neoplasm | NA | GAD | Detail | |
| 0.005 | Laryngeal neoplasm | NA | GAD | Detail | |
| <0.001 | leprosy | NA | BeFree | Detail | |
| 0.007 | leukemia | NA | GAD | Detail | |
| 0.005 | chronic lymphocytic leukemia | NA | GAD | Detail | |
| 0.001 | Acute lymphocytic leukemia | NA | BeFree | Detail | |
| 0.006 | Leukemia, Lymphocytic, Acute, L1 | NA | BeFree,GAD | Detail | |
| 0.002 | Leukemia, Myelocytic, Acute | NA | BeFree | Detail | |
| <0.001 | Leukoplakia | All the results demonstrate an association between CYP2E1 genetic polymorphism a... | BeFree | 25104199 | Detail |
| 0.005 | Leukoplakia, Oral | Role of CYP2E1 genetic polymorphism in the development of oral leukoplakia among... | BeFree,GAD | 25104199 | Detail |
| 0.018 | liver cirrhosis | CYP2C19 were decreased in all end-stage liver diseases and CYP2E1 also decreased... | BeFree,GAD,LHGDN | 25024626 | Detail |
| 0.144 | Liver Cirrhosis, Alcoholic | CYP2C19 were decreased in all end-stage liver diseases and CYP2E1 also decreased... | BeFree,CTD_human,GAD,LHGDN | 25024626 | Detail |
| 0.096 | Liver diseases | NA | BeFree,GAD,RGD | Detail | |
| 0.016 | Alcoholic Liver Diseases | Targeting the JNK pathway or its downstream effectors may be a useful therapeuti... | BeFree,GAD,LHGDN | 25462060 | Detail |
| 0.130 | Liver neoplasms | HBx inhibits CYP2E1 gene expression via downregulating HNF4α in human hepatoma c... | BeFree,CTD_human,GAD | 25238230 | Detail |
| 0.120 | Liver Neoplasms, Experimental | NA | CTD_human | Detail | |
| 0.008 | Chronic Obstructive Airway Disease | NA | BeFree,GAD,LHGDN | Detail | |
| 0.128 | Lung Neoplasms | NA | BeFree,CTD_human,GAD,LHGDN | Detail | |
| <0.001 | Lupus Erythematosus, Systemic | Our data suggest a protective role of the GSTP1*Ile/Val heterozygous genotype ag... | BeFree | 24981927 | Detail |
| 0.006 | lymphoma | NA | BeFree,GAD | Detail | |
| 0.003 | Lymphoma, Follicular | NA | BeFree,GAD | Detail | |
| 0.134 | Lymphoma, Non-Hodgkin | NA | BeFree,CTD_human,GAD | Detail | |
| 0.003 | melanoma | NA | BeFree,GAD | Detail | |
| 0.002 | Mesothelioma | NA | GAD | Detail | |
| 0.003 | Metaplasia | NA | LHGDN | Detail | |
| 0.012 | Mouth Neoplasms | NA | GAD | Detail | |
| 0.012 | Nasopharyngeal Neoplasms | NA | GAD,LHGDN | Detail | |
| 0.120 | Necrosis | NA | CTD_human | Detail | |
| 0.120 | Neoplasm Invasiveness | NA | CTD_human | Detail | |
| 0.002 | Neoplasms, Multiple Primary | NA | GAD | Detail | |
| <0.001 | acoustic neuroma | NA | BeFree | Detail | |
| <0.001 | nicotine dependence | NA | BeFree | Detail | |
| 0.205 | obesity | The enhanced levels of CYP2E1 and increased oxidative stress in obesity play a s... | BeFree,CTD_human,GAD,RGD | 25180626 | Detail |
| 0.205 | obesity | In the small intestine and colon, no changes of CYP enzymes were detected except... | BeFree,CTD_human,GAD,RGD | 25998026 | Detail |
| 0.007 | Occupational Diseases | NA | BeFree,GAD | Detail | |
| 0.002 | Oropharyngeal Neoplasms | NA | GAD | Detail | |
| 0.002 | Degenerative polyarthritis | NA | GAD | Detail | |
| 0.002 | Bone necrosis | NA | GAD | Detail | |
| 0.006 | pancreatitis | NA | BeFree,GAD,LHGDN | Detail | |
| 0.130 | Parkinson disease | NA | BeFree,CTD_human,GAD | Detail | |
| <0.001 | Peptic Ulcer | NA | BeFree | Detail | |
| 0.002 | periodontitis | NA | GAD | Detail | |
| 0.002 | Peripheral neuropathy | NA | GAD | Detail | |
| 0.002 | Pleural Neoplasms | NA | GAD | Detail | |
| 0.003 | pneumonia | NA | BeFree,GAD | Detail | |
| 0.002 | pre-eclampsia | NA | GAD | Detail | |
| 0.002 | Pregnancy Complications | NA | GAD | Detail | |
| 0.005 | Prenatal Exposure Delayed Effects | NA | GAD | Detail | |
| 0.120 | Prostatic Neoplasms | NA | CTD_human | Detail | |
| 0.003 | Rectal Neoplasms | NA | LHGDN | Detail | |
| 0.080 | Reperfusion Injury | NA | RGD | Detail | |
| 0.002 | Respiratory Tract Diseases | NA | GAD | Detail | |
| 0.002 | Respiratory Tract Neoplasms | NA | GAD | Detail | |
| <0.001 | Retroviridae Infections | NA | BeFree | Detail | |
| 0.003 | schizophrenia | NA | BeFree,GAD | Detail | |
| 0.002 | systemic scleroderma | NA | GAD | Detail | |
| 0.002 | Stomach Diseases | NA | GAD | Detail | |
| 0.034 | Stomach Neoplasms | NA | GAD,LHGDN | Detail | |
| 0.003 | thalassemia | NA | LHGDN | Detail | |
| <0.001 | Tobacco Dependence | NA | BeFree | Detail | |
| 0.002 | Tobacco use disorder | NA | GAD | Detail | |
| 0.002 | Trisomy | NA | GAD | Detail | |
| 0.012 | tuberculosis | The aim of this study was to determine, for the first time, the frequency of slo... | BeFree,GAD | 25544508 | Detail |
| 0.008 | Tuberculosis, Pulmonary | NA | BeFree,GAD | Detail | |
| 0.120 | Adverse reaction to drug | NA | CTD_human | Detail | |
| 0.002 | Ureteral Neoplasms | NA | GAD | Detail | |
| <0.001 | Vomiting | NA | BeFree | Detail | |
| 0.002 | Helicobacter Infections | NA | GAD | Detail | |
| 0.002 | motor neuron disease | NA | GAD | Detail | |
| <0.001 | acute leukemia | NA | BeFree | Detail | |
| 0.003 | Alcohol abuse | NA | BeFree,GAD | Detail | |
| 0.003 | Pancreatitis, Chronic | NA | BeFree,GAD | Detail | |
| <0.001 | Squamous cell carcinoma of lung | NA | BeFree | Detail | |
| <0.001 | Small cell carcinoma of lung | NA | BeFree | Detail | |
| 0.002 | Premature Birth | NA | GAD | Detail | |
| <0.001 | Adenocarcinoma of lung (disorder) | In summary, this meta-analysis indicates that CYP2E1 RsaI polymorphism is associ... | BeFree | 25336053 | Detail |
| 0.003 | esophageal carcinoma | NA | BeFree | Detail | |
| 0.005 | Malignant neoplasm of mouth | NA | BeFree,GAD | Detail | |
| <0.001 | Malignant neoplasm of pharynx | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of brain | NA | BeFree | Detail | |
| 0.003 | adrenoleukodystrophy | The presentations are focused on genetic polymorphisms of ethanol metabolizing e... | BeFree | 24816574 | Detail |
| 0.003 | adrenoleukodystrophy | Taken together our data support a novel Cyp2e1-circadian clock protein mechanism... | BeFree | 25462064 | Detail |
| 0.002 | Cervical Intraepithelial Neoplasia | NA | GAD | Detail | |
| 0.007 | Squamous Cell Neoplasms | NA | GAD,LHGDN | Detail | |
| 0.003 | adult brain tumor | NA | BeFree,GAD | Detail | |
| 0.002 | Lip and oral cavity carcinoma | NA | BeFree | Detail | |
| <0.001 | Obsessions | Among currently dependent patients CAT -262T allele carriers had higher AUDIT sc... | BeFree | 25514903 | Detail |
| <0.001 | Alcohol-Related Disorders | NA | BeFree | Detail | |
| 0.002 | Substance-Related Disorders | NA | GAD | Detail | |
| 0.006 | Leukemia, Lymphocytic, Acute, L1 | DNA repair XRCC1 Arg399Gln polymorphism alone, and in combination with CYP2E1 po... | BeFree | 20394984 | Detail |
| <0.001 | Fibrosis, Liver | NA | BeFree | Detail | |
| <0.001 | Hepatitis, Autoimmune | NA | BeFree | Detail | |
| <0.001 | Halothane Hepatitis | NA | BeFree | Detail | |
| 0.055 | Malignant neoplasm of lung | Updated meta-analysis of the association between CYP2E1 RsaI/PstI polymorphisms ... | BeFree,GAD | 25040958 | Detail |
| 0.055 | Malignant neoplasm of lung | Association between the CYP2E1 polymorphisms and lung cancer risk: a meta-analys... | BeFree,GAD | 25336053 | Detail |
| 0.055 | Malignant neoplasm of lung | Association of CYP2E1 and NAT2 polymorphisms with lung cancer susceptibility amo... | BeFree,GAD | 25422202 | Detail |
| 0.002 | age related macular degeneration | NA | GAD | Detail | |
| 0.080 | Sepsis | NA | RGD | Detail | |
| <0.001 | Carcinoma, Small Cell | NA | BeFree | Detail | |
| <0.001 | Acquired aplastic anemia | NA | BeFree | Detail | |
| <0.001 | Erythrocytosis due to low atmospheric pressure | CYP17A1 and CYP2E1 variants associated with high altitude polycythemia in Tibeta... | BeFree | 25917616 | Detail |
| <0.001 | gastric adenocarcinoma | NA | BeFree | Detail | |
| 0.016 | Cancer of Head and Neck | NA | BeFree,GAD | Detail | |
| <0.001 | Liver and Intrahepatic Biliary Tract Carcinoma | NA | BeFree | Detail | |
| 0.001 | Squamous cell carcinoma of esophagus | NA | BeFree | Detail | |
| 0.003 | cervix carcinoma | NA | BeFree,GAD | Detail | |
| <0.001 | Squamous intraepithelial lesion | NA | BeFree | Detail | |
| <0.001 | High-Grade Squamous Intraepithelial Lesions | NA | BeFree | Detail | |
| <0.001 | Chronic liver disease | NA | BeFree | Detail | |
| 0.003 | Malignant neoplasm of liver | NA | BeFree,GAD | Detail | |
| 0.002 | Malignant neoplasm of pancreas | NA | GAD | Detail | |
| <0.001 | Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site | NA | BeFree | Detail | |
| 0.010 | Malignant neoplasm of prostate | NA | BeFree,GAD | Detail | |
| 0.020 | Pancreatitis, Alcoholic | NA | BeFree,GAD | Detail | |
| <0.001 | Cirrhosis - non-alcoholic | NA | BeFree | Detail | |
| <0.001 | Non-alcoholic Fatty Liver Disease | NA | BeFree | Detail | |
| <0.001 | Gastrointestinal symptom | NA | BeFree | Detail | |
| 0.001 | Hepatitis C, Chronic | NA | BeFree | Detail | |
| 0.029 | Malignant neoplasm of esophagus | NA | BeFree,GAD | Detail | |
| <0.001 | Carcinoma of larynx | Effects of SNPs (CYP1B1*2 G355T, CYP1B1*3 C4326G, and CYP2E1*5 G-1293C), smoking... | BeFree | 25299224 | Detail |
| 0.005 | Carcinogenesis | The mechanisms by which chronic alcohol consumption enhances carcinogenesis incl... | BeFree | 25427901 | Detail |
| 0.005 | Carcinogenesis | Since etheno-DNA adducts are strong mutagens producing various types of base pai... | BeFree | 25462066 | Detail |
| <0.001 | prostate carcinoma | NA | BeFree | Detail | |
| 0.002 | Epithelial ovarian cancer | NA | GAD | Detail | |
| 0.001 | breast carcinoma | NA | BeFree | Detail | |
| 0.010 | Carcinoma of lung | Updated meta-analysis of the association between CYP2E1 RsaI/PstI polymorphisms ... | BeFree | 25040958 | Detail |
| 0.010 | Carcinoma of lung | Association between the CYP2E1 polymorphisms and lung cancer risk: a meta-analys... | BeFree | 25336053 | Detail |
| 0.010 | Carcinoma of lung | Association of CYP2E1 and NAT2 polymorphisms with lung cancer susceptibility amo... | BeFree | 25422202 | Detail |
| 0.002 | Carcinoma of bladder | Functional RsaI/PstI polymorphism in cytochrome P450 2E1 contributes to bladder ... | BeFree | 24998574 | Detail |
| <0.001 | End Stage Liver Disease | CYP2C19 were decreased in all end-stage liver diseases and CYP2E1 also decreased... | BeFree | 25024626 | Detail |
| <0.001 | Pharyngeal Carcinoma | NA | BeFree | Detail | |
| <0.001 | adult acute lymphocytic leukemia | NA | BeFree | Detail | |
| <0.001 | Malignant Squamous Cell Neoplasm | NA | BeFree | Detail | |
| 0.002 | Alcohol-Induced Disorders, Nervous System | NA | GAD | Detail | |
| <0.001 | Helicobacter pylori infection | No significant association between H. pylori infection and CYP2E1 RsaI polymorph... | BeFree | 25374213 | Detail |
| <0.001 | Adenoviral infections | NA | BeFree | Detail | |
| <0.001 | Cholestatic liver disease | NA | BeFree | Detail | |
| 0.141 | Drug-Induced Liver Injury | NA | CTD_human,GAD | Detail | |
| <0.001 | Cardiomyopathies | NA | BeFree | Detail | |
| 0.002 | Genomic Instability | NA | GAD | Detail | |
| 0.002 | Malignant neoplasm of ovary | NA | GAD | Detail | |
| 0.003 | Squamous cell carcinoma of the head and neck | NA | BeFree,GAD | Detail | |
| 0.001 | Hepatitis, Drug-Induced | NA | BeFree | Detail | |
| 0.007 | Systemic arterial pressure | NA | GAD | Detail | |
| <0.001 | Adenoma of large intestine | NA | BeFree | Detail | |
| <0.001 | childhood leukemia | NA | BeFree | Detail | |
| <0.001 | Alcoholic liver damage | NA | BeFree | Detail | |
| 0.120 | Micronuclei, Chromosome-Defective | NA | CTD_human | Detail | |
| 0.011 | Mammary Neoplasms | NA | GAD,LHGDN | Detail | |
| <0.001 | Hepatocarcinogenesis | The elucidation of a HBx-HNF4α-CYP2E1 pathway provides novel insight into the mo... | BeFree | 25238230 | Detail |
| 0.042 | colorectal cancer | NA | BeFree,GAD | Detail | |
| <0.001 | Latent Tuberculosis | NA | BeFree | Detail | |
| 0.005 | Cirrhosis | CYP2C19 were decreased in all end-stage liver diseases and CYP2E1 also decreased... | BeFree,GAD | 25024626 | Detail |
| 0.002 | Slow acetylator due to N-acetyltransferase enzyme variant | The proposed risk-associated genotypes are NAT2 slow acetylator (without wild-ty... | BeFree | 24593909 | Detail |
| 0.002 | Slow acetylator due to N-acetyltransferase enzyme variant | The genotypes involved in the susceptibility of gastric carcinoma were CYP2E1(c1... | BeFree | 25245011 | Detail |
| 0.002 | Slow acetylator due to N-acetyltransferase enzyme variant | Most Moroccans are homozygous for c1 allele of CYP2E1 gene which aggravates hepa... | BeFree | 25544508 | Detail |
| 0.003 | coronary artery disease | NA | BeFree,GAD | Detail | |
| 0.020 | Precursor Cell Lymphoblastic Leukemia Lymphoma | NA | BeFree,GAD,LHGDN | Detail | |
| <0.001 | Urothelial Carcinoma | NA | BeFree | Detail | |
| 0.145 | liver carcinoma | Similar decreases (about 50%) of CYP2B6, CYP2C9, CYP2C19, CYP2D6 and CYP2E1 were... | BeFree,CTD_human,GAD,LHGDN | 25024626 | Detail |
| 0.145 | liver carcinoma | Cytochrome P450 2E1 gene polymorphism and alcohol drinking on the risk of hepato... | BeFree,CTD_human,GAD,LHGDN | 25185993 | Detail |
| 0.145 | liver carcinoma | HBx inhibits CYP2E1 gene expression via downregulating HNF4α in human hepatoma c... | BeFree,CTD_human,GAD,LHGDN | 25238230 | Detail |
| <0.001 | Steatohepatitis | NA | BeFree | Detail | |
| <0.001 | Alcoholic Steatohepatitis | NA | BeFree | Detail | |
| 0.002 | Nasopharyngeal carcinoma | The results suggested that the Arg399Gln polymorphism of XRCC1 gene, the 1G/2G p... | BeFree | 25481674 | Detail |
| <0.001 | Alcohol Related Birth Defect | NA | BeFree | Detail | |
| <0.001 | Nonalcoholic Steatohepatitis | The liver sections were evaluated for histopathological alterations of NASH and ... | BeFree | 25180626 | Detail |
| 0.128 | adenocarcinoma | NA | BeFree,CTD_human,GAD | Detail | |
| 0.003 | adenoma | NA | BeFree,GAD | Detail | |
| <0.001 | alcohol use disorder | NA | BeFree | Detail | |
| 0.169 | Alcoholic Intoxication, Chronic | We investigated whether variation in genes encoding cytochrome P450 2E1 (CYP2E1)... | BeFree,CTD_human,GAD,LHGDN | 24567230 | Detail |
| <0.001 | aplastic anemia | NA | BeFree | Detail | |
| <0.001 | Cooley's anemia | NA | BeFree | Detail | |
| 0.002 | Aneuploidy | NA | GAD | Detail | |
| <0.001 | antisocial personality disorder | NA | BeFree | Detail | |
| <0.001 | Anxiety Disorders | We investigated whether variation in genes encoding cytochrome P450 2E1 (CYP2E1)... | BeFree | 24567230 | Detail |
| <0.001 | Anxiety Disorders | Our findings suggest that the CAT c.-262C>T genetic polymorphism influences the ... | BeFree | 25514903 | Detail |
| <0.001 | arteriosclerosis | NA | BeFree | Detail | |
| 0.002 | arthritis | NA | GAD | Detail | |
| 0.002 | As If Personality | NA | GAD | Detail | |
| 0.005 | asthma | NA | GAD | Detail | |
| 0.005 | atherosclerosis | NA | BeFree,GAD | Detail | |
| 0.003 | beta thalassemia | NA | LHGDN | Detail | |
| 0.016 | Malignant neoplasm of urinary bladder | Functional RsaI/PstI polymorphism in cytochrome P450 2E1 contributes to bladder ... | BeFree,GAD | 24998574 | Detail |
| 0.005 | Bladder Neoplasm | NA | GAD,LHGDN | Detail | |
| 0.008 | Malignant neoplasm of breast | NA | BeFree,GAD | Detail | |
| 0.002 | bronchitis | NA | GAD | Detail | |
| 0.002 | Nasopharyngeal carcinoma | The results suggested that the Arg399Gln polymorphism of XRCC1 gene, the 1G/2G p... | BeFree | 25481674 | Detail |
| <0.001 | Malignant neoplasm of larynx | Effects of SNPs (CYP1B1*2 G355T, CYP1B1*3 C4326G, and CYP2E1*5 G-1293C), smoking... | BeFree | 25299224 | Detail |
| <0.001 | Rectal Carcinoma | NA | BeFree | Detail | |
| 0.122 | Non-small cell lung carcinoma | NA | BeFree,CTD_human | Detail |
Annotation
Annotations
| Descrption | Source | Links |
|---|---|---|
| When we examined the associations between several single-nucleotide polymorphisms and ESCC in those ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The elucidation of a HBx-HNF4α-CYP2E1 pathway provides novel insight into the molecular mechanism un... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| All the results demonstrate an association between CYP2E1 genetic polymorphism and leukoplakia risk,... | DisGeNET | Detail |
| Role of CYP2E1 genetic polymorphism in the development of oral leukoplakia among tobacco users in No... | DisGeNET | Detail |
| CYP2C19 were decreased in all end-stage liver diseases and CYP2E1 also decreased in alcoholic cirrho... | DisGeNET | Detail |
| CYP2C19 were decreased in all end-stage liver diseases and CYP2E1 also decreased in alcoholic cirrho... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Targeting the JNK pathway or its downstream effectors may be a useful therapeutic approach to the ox... | DisGeNET | Detail |
| HBx inhibits CYP2E1 gene expression via downregulating HNF4α in human hepatoma cells. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Our data suggest a protective role of the GSTP1*Ile/Val heterozygous genotype against the SLE in Eur... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The enhanced levels of CYP2E1 and increased oxidative stress in obesity play a significant role in t... | DisGeNET | Detail |
| In the small intestine and colon, no changes of CYP enzymes were detected except for increased expre... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
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| The aim of this study was to determine, for the first time, the frequency of slow acetylators in Mor... | DisGeNET | Detail |
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| In summary, this meta-analysis indicates that CYP2E1 RsaI polymorphism is associated with lung cance... | DisGeNET | Detail |
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| The presentations are focused on genetic polymorphisms of ethanol metabolizing enzymes and the role ... | DisGeNET | Detail |
| Taken together our data support a novel Cyp2e1-circadian clock protein mechanism for alcohol-induced... | DisGeNET | Detail |
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| Among currently dependent patients CAT -262T allele carriers had higher AUDIT scores (P = 0.023), wh... | DisGeNET | Detail |
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| DNA repair XRCC1 Arg399Gln polymorphism alone, and in combination with CYP2E1 polymorphisms signific... | DisGeNET | Detail |
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| Updated meta-analysis of the association between CYP2E1 RsaI/PstI polymorphisms and lung cancer risk... | DisGeNET | Detail |
| Association between the CYP2E1 polymorphisms and lung cancer risk: a meta-analysis. | DisGeNET | Detail |
| Association of CYP2E1 and NAT2 polymorphisms with lung cancer susceptibility among Mongolian and Han... | DisGeNET | Detail |
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| CYP17A1 and CYP2E1 variants associated with high altitude polycythemia in Tibetans at the Qinghai-Ti... | DisGeNET | Detail |
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| Effects of SNPs (CYP1B1*2 G355T, CYP1B1*3 C4326G, and CYP2E1*5 G-1293C), smoking, and drinking on su... | DisGeNET | Detail |
| The mechanisms by which chronic alcohol consumption enhances carcinogenesis include acetaldehyde (AA... | DisGeNET | Detail |
| Since etheno-DNA adducts are strong mutagens producing various types of base pair substitution mutat... | DisGeNET | Detail |
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| Updated meta-analysis of the association between CYP2E1 RsaI/PstI polymorphisms and lung cancer risk... | DisGeNET | Detail |
| Association between the CYP2E1 polymorphisms and lung cancer risk: a meta-analysis. | DisGeNET | Detail |
| Association of CYP2E1 and NAT2 polymorphisms with lung cancer susceptibility among Mongolian and Han... | DisGeNET | Detail |
| Functional RsaI/PstI polymorphism in cytochrome P450 2E1 contributes to bladder cancer susceptibilit... | DisGeNET | Detail |
| CYP2C19 were decreased in all end-stage liver diseases and CYP2E1 also decreased in alcoholic cirrho... | DisGeNET | Detail |
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| No significant association between H. pylori infection and CYP2E1 RsaI polymorphism in terms of stom... | DisGeNET | Detail |
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| The elucidation of a HBx-HNF4α-CYP2E1 pathway provides novel insight into the molecular mechanism un... | DisGeNET | Detail |
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| CYP2C19 were decreased in all end-stage liver diseases and CYP2E1 also decreased in alcoholic cirrho... | DisGeNET | Detail |
| The proposed risk-associated genotypes are NAT2 slow acetylator (without wild-type NAT2*4 allele), C... | DisGeNET | Detail |
| The genotypes involved in the susceptibility of gastric carcinoma were CYP2E1(c1/c1), NAT2M1(T/T), N... | DisGeNET | Detail |
| Most Moroccans are homozygous for c1 allele of CYP2E1 gene which aggravates hepatotoxicity in slow a... | DisGeNET | Detail |
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| Similar decreases (about 50%) of CYP2B6, CYP2C9, CYP2C19, CYP2D6 and CYP2E1 were observed in HCC, as... | DisGeNET | Detail |
| Cytochrome P450 2E1 gene polymorphism and alcohol drinking on the risk of hepatocellular carcinoma: ... | DisGeNET | Detail |
| HBx inhibits CYP2E1 gene expression via downregulating HNF4α in human hepatoma cells. | DisGeNET | Detail |
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| The results suggested that the Arg399Gln polymorphism of XRCC1 gene, the 1G/2G polymorphism of MMP-1... | DisGeNET | Detail |
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| The liver sections were evaluated for histopathological alterations of NASH and stained for cytochro... | DisGeNET | Detail |
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| We investigated whether variation in genes encoding cytochrome P450 2E1 (CYP2E1) or acetaldehyde-met... | DisGeNET | Detail |
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| We investigated whether variation in genes encoding cytochrome P450 2E1 (CYP2E1) or acetaldehyde-met... | DisGeNET | Detail |
| Our findings suggest that the CAT c.-262C>T genetic polymorphism influences the susceptibility to al... | DisGeNET | Detail |
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| Functional RsaI/PstI polymorphism in cytochrome P450 2E1 contributes to bladder cancer susceptibilit... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The results suggested that the Arg399Gln polymorphism of XRCC1 gene, the 1G/2G polymorphism of MMP-1... | DisGeNET | Detail |
| Effects of SNPs (CYP1B1*2 G355T, CYP1B1*3 C4326G, and CYP2E1*5 G-1293C), smoking, and drinking on su... | DisGeNET | Detail |
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Overlapped Transcript Coordinates
| Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
|---|
Overlapped Transcript
| Gene | Transcript ID | Chromosome | Start | Stop | Links |
|---|
- Gene
- -
- dbSNP
- rs386493716 dbSNP
- Genome
- hg38
- Position
- chr10:133,520,406-133,539,123
- Variant Type
- snv
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