Annotation Detail

Information
Associated Genes
CYP2E1
Associated Variants
CYP2E1 MUTATION
CYP2E1 MUTATION
Associated Disease
squamous cell carcinoma
Source Database
DisGeNET
Description
When we examined the associations between several single-nucleotide polymorphisms and ESCC in those with and without FHC, the associations of variant genotypes in cytochrome P450 (CYP) 2C19 and CYP2D6 and the wild genotype of CYP2E1 with ESCC were much stronger in those with FHC.
Pubmed
26125444
Section of the abstract supporting the evidence
RESULTS
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
10
Original source reporting the Gene Disease association
BeFree,GAD,LHGDN
DisGENET score for the Gene Disease association
0.0442114826289284
Drugs