Annotation Detail

Information
Associated Genes
CYP2E1
Associated Variants
CYP2E1 MUTATION
CYP2E1 MUTATION
Associated Disease
Slow acetylator due to N-acetyltransferase enzyme variant
Source Database
DisGeNET
Description
The proposed risk-associated genotypes are NAT2 slow acetylator (without wild-type NAT2*4 allele), CYP2E1 *1A/*1A (homozygous wild type), homozygous null GSTM1 genotype and MnSOD mutant C allele.
Pubmed
24593909
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
8
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00190009310456212
Drugs