Annotation Detail

Information
Associated Genes
CYP2E1
Associated Variants
CYP2E1 MUTATION
CYP2E1 MUTATION
Associated Disease
Alcoholic Liver Diseases
Source Database
DisGeNET
Description
Targeting the JNK pathway or its downstream effectors may be a useful therapeutic approach to the oxidative stress generated by CYP2E1 in alcoholic liver disease.
Pubmed
25462060
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
5
Original source reporting the Gene Disease association
BeFree,GAD,LHGDN
DisGENET score for the Gene Disease association
0.0157212224939192
Drugs