Tobacco Dependence

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Information
Disease name
Tobacco Dependence
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT03612960 Active, not recruiting N/A Measuring Neuroadaptations in Response to Very Low Nicotine Content Cigarettes February 20, 2020 January 2024
NCT04061720 Active, not recruiting N/A Identifying Effective Treatment for Veterans Unwilling to Quit Smoking November 12, 2019 September 30, 2025
NCT00270231 Completed Phase 2 Effects of Naltrexone on Nicotine Reinforcement March 2004 October 2005
NCT00296647 Completed Phase 4 Smoking Cessation Intervention: Effectiveness in Primary Care September 2004 December 2010
NCT00301626 Completed N/A ROSCAP: Reduction of Smoking in Cardiac Patients Study October 2000 January 2005
NCT00394420 Completed N/A Emergency Department Telephone Quitline September 2003 April 2006
NCT00435344 Completed Phase 2 Provider and Peer Delivered Youth Smoking Intervention February 1999 January 2004
NCT00449293 Completed N/A Behavioral Therapy for Reduction in Smoking Craving October 2006 May 2008
NCT00484692 Completed Phase 4 Randomized Trial of Ultrashort Psychotherapy vs Sustained-Release Bupropion for Smoking Cessation July 2005 January 2007
NCT00495352 Completed Phase 4 The Pharmacogenetic Study , Readiness to Change, and Pharmacological Intervention for Smoking Cessation in Schizophrenia January 2006 December 2008
NCT00501007 Completed Predictors of Treatment Outcome for Smokers With and Without Schizophrenia February 2005 January 2013
NCT00503230 Completed Phase 3 Reducing Ethnic Health Disparities: Motivating HIV+ Latinos to Quit Smoking October 2005 July 2011
NCT03496077 Completed N/A Addictive Potential of LCCs in Dual Users August 28, 2018 December 31, 2020
NCT00170079 Completed N/A Prolonged Smoking Cessation Using Prescription Step Care April 2005 June 2011
NCT01928719 Completed N/A Reduced Nicotine Content Cigarettes in Smokers of Lower Socioeconomic Status September 9, 2015 February 23, 2018
NCT01928758 Completed N/A Reduced Nicotine Cigarettes in Smokers With Mood and Anxiety Disorders September 2015 March 23, 2018
NCT01995123 Completed N/A Behavioral Activation for Smoking Cessation in PTSD September 8, 2014 March 29, 2019
NCT02019459 Completed Phase 2 Very Low Nicotine Cigarettes in Smokers With Schizophrenia November 17, 2014 August 31, 2017
NCT02137902 Completed N/A Healing and Empowering Alaskan Lives Towards Healthy-Hearts Study June 1, 2015 March 2020
NCT02202499 Completed Early Phase 1 Translating Extinction Research to Improve Pharmacotherapy for Tobacco Dependence July 17, 2014 June 14, 2019
NCT02347787 Completed N/A A Multi-center Trial of IMPaCT CHW Support for Chronically-ill Patients January 28, 2015 July 2018
NCT02355665 Completed Phase 3 Study to Determine the Efficacy and Safety of a Novel Nicotine Replacement Therapy January 31, 2015 February 10, 2016
NCT02478697 Completed N/A Tobacco Treatment for Employable Californians, Total IMPACT Study October 2015 September 12, 2018
NCT02515981 Completed N/A New Hampshire Medicaid Wellness Incentive Program May 2012 December 2018
NCT02564289 Completed Cardiovascular Effects of Chronic Snus Use September 2015 March 2016
NCT02611076 Completed N/A Smoking-cessation: A Spanish-Language Clinical Trial October 15, 2015 October 28, 2021
NCT02656745 Completed N/A Clinical Trial of Smoking Cessation Mobile Phone Program May 2016 June 2017
NCT02695225 Completed N/A Tobacco Cessation Interventions With Ohio Appalachian Smokers November 2010 October 2014
NCT02764385 Completed N/A Using a Teachable Moment Communication Process to Improve Outcomes of Quitline Referrals August 2016 April 2019
NCT02773836 Completed European Regulatory Science on Tobacco: Policy Implementation to Reduce Lung Diseases (EUREST-PLUS) June 15, 2016 May 6, 2018
NCT03050853 Completed N/A The Appeal and Impact of E-cigarettes in Smokers With SMI March 1, 2017 January 31, 2021
NCT03130179 Completed Phase 1 A Bioequivalence Study Between Two Nicotine Replacement Therapies in Adult Healthy Smokers Motivated to Quit. March 20, 2017 June 29, 2017
NCT03176784 Completed Phase 4 UW Quitting Using Intensive Treatment Study (QUITS) November 11, 2017 July 9, 2020
NCT03194958 Completed N/A Helping Poor Smokers Quit June 5, 2017 July 1, 2022
NCT03259360 Completed N/A A Facebook Intervention for Young Sexual and Gender Minority Smokers April 23, 2018 February 28, 2020
NCT03259607 Completed Phase 1 Clinical Study to Assess Bioequivalence Between Nicorette Extra Mint Gum and Nicorette® Mint Gum in Healthy Smokers August 14, 2017 January 9, 2018
NCT03382093 Completed N/A Personalized Feedback for Smokers With Elevated Anxiety Sensitivity August 23, 2017 June 1, 2019
NCT00133757 Completed Phase 1 Use of Pharmacotherapy to Reduce Cue-responsiveness in Smokers June 2005 May 2006
NCT03553992 Completed N/A An Extended Facebook Intervention for Young Sexual and Gender Minority Smokers October 29, 2018 July 7, 2019
NCT03557294 Completed Phase 4 Varenicline OTC Trial on Efficacy and Safety May 7, 2018 April 16, 2022
NCT03625986 Completed N/A Does Switching to Nicotine Containing Electronic Cigarettes Reduce Health Risk Markers April 22, 2022 February 23, 2024
NCT03626064 Completed N/A The PROMPT Pilot Study June 2014 March 2017
NCT03694327 Completed N/A Innovative Digital Therapeutic for Smoking Cessation October 24, 2018 March 14, 2019
NCT03841292 Completed N/A Using Non-invasive Brain Stimulation (tDCS) With Varenicline for Treating Tobacco Dependence October 1, 2018 January 31, 2022
NCT03918031 Completed N/A Personalized Feedback for Distress Intolerant Smokers July 15, 2019 October 24, 2021
NCT04595318 Completed Phase 4 Varenicline for Co-occurring Cannabis and Tobacco Use January 2015 July 2015
NCT04969198 Completed Phase 2 UW Withdraw From Tobacco Study July 13, 2021 September 21, 2022
NCT05066126 Completed N/A Mixed Presentation on Social Media November 15, 2021 August 10, 2022
NCT05279053 Completed Mapping Brain Glutamate in Humans: Sex Differences in Cigarette Smokers April 1, 2021 March 31, 2023
NCT00656500 Completed N/A Quitline Use in Surgical Patients July 2007 June 2011
NCT00722124 Completed Phase 2/Phase 3 S-Adenosyl-L-Methionine (SAMe) for Smoking Abstinence September 2008 June 2010
NCT00747643 Completed N/A Varenicline Effects on Cue Reactivity and Smoking Reward/Reinforcement September 2008 August 2010
NCT00749463 Completed Phase 4 Evaluation of the Safety Profile, Quit and Reduction Rate After Nicorette® Gum and Patch Treatment February 2009 November 2009
NCT00755716 Completed Phase 3 Topiramate Alone and in Combination With the Nicotine Patch for Smoking Cessation: A Pilot Study April 2006 August 2013
NCT00777569 Completed Phase 2 Comparisons of Nicotine-free Cigarettes, Extra Low Nicotine Cigarettes vs. Medicinal Nicotine March 2005 November 2006
NCT00789074 Completed Phase 3 Use of Varenicline for 4-weeks Prior to Quitting July 2009 March 2010
NCT00873535 Completed N/A Effect of Varenicline on Reactivity to Smoking and Drinking Cues October 2008 January 2010
NCT00918307 Completed Phase 3 Efficacy and Safety of Varenicline Among HIV-infected Patients October 2009 July 2014
NCT00973622 Completed N/A Changing Thought and Action in Tobacco Dependence With Transcranial Magnetic Stimulation October 2009 January 2012
NCT01018394 Completed Phase 2/Phase 3 Nicotine Lozenge or Tobacco-Free Snuff for Smokeless Tobacco Reduction January 2009 July 2012
NCT01067586 Completed Novel Determinants and Measures of Smokeless Tobacco Use: Study 1 February 2010 April 2013
NCT01084603 Completed N/A Single-dose Nicotine Pharmacokinetics With a New Oral Nicotine Replacement Product March 2009 June 2009
NCT01084707 Completed N/A Multiple-dose Nicotine Pharmacokinetics With a New Oral Nicotine Replacement Product. January 2009 April 2009
NCT01091363 Completed N/A Tobacco Dependence Treatment for Asian Americans October 2009 January 2014
NCT01113424 Completed N/A Bioequivalence Between Nicotine Replacement Products and Nicorette® Gum September 2008 December 2008
NCT01152723 Completed N/A Pharmacokinetics With Two New Oral Nicotine Replacement Products and Nicorette® Gum March 2008 May 2008
NCT01152736 Completed N/A Pharmacokinetics With a New Oral Nicotine Replacement Product and Nicorette® Gum November 2008 January 2009
NCT01152749 Completed N/A Bioequivalence Between an Oral Nicotine Replacement Product and Nicorette® Gum December 2009 May 2010
NCT01184664 Completed Phase 3 Combination of Nicotine Replacement Therapy (NRT) and Varenicline to Increase Cessation of Tobacco (CONVICT Study) April 2011 October 2011
NCT01206010 Completed Phase 3 Tailoring Varenicline to Individual Needs (TVIN Study) July 2011 February 2013
NCT01208935 Completed Phase 2/Phase 3 Safety, Tolerability and Efficacy of the Nicotine Patch and Gum for the Treatment of Adolescent Tobacco Dependence August 1999 August 2004
NCT01227720 Completed N/A Comparative Pharmacokinetic Study of New Oral Nicotine Replacement Therapy Products. August 2009 January 2010
NCT01228617 Completed N/A Single-dose Pharmacokinetics of Oral Nicotine Replacement Products September 2007 October 2007
NCT01234792 Completed N/A Single-dose Nicotine Pharmacokinetics With Three Oral Nicotine Replacement Products. A Study in Healthy Smokers. May 2008 June 2008
NCT01234896 Completed N/A Single-dose Nicotine Pharmacokinetics With Four Oral Nicotine Replacement Products October 2010 December 2010
NCT01238627 Completed N/A Bioequivalence Between Two Oral Nicotine Sublingual Tablets, 2 mg and 4 mg September 2007 November 2007
NCT01238640 Completed N/A Bioequivalence Between Two New Oral Nicotine Replacement Therapy Products and Nicorette® Microtab August 2008 November 2008
NCT01250301 Completed N/A De-nicotinised Cigarettes Study July 2011 July 2012
NCT01321931 Completed Phase 1 Multiple-dose Nicotine Pharmacokinetics With Three Oral Nicotine Replacement Products February 2011 June 2011
NCT01321944 Completed N/A Direct to Smoker Outreach in a Health Care Setting July 2009 July 2010
NCT01334736 Completed N/A A Study of Novel Smoking Cessation Interventions in Current and Former Injection Drug Users April 2011 July 2012
NCT01347112 Completed Phase 2/Phase 3 Varenicline Treatment for Active Alcoholic Smokers June 2011 March 2014
NCT01350011 Completed Phase 3 Tobacco Intervention in Buprenorphine Treatment April 1, 2011 December 1, 2016
NCT01368016 Completed N/A Nicotine Pharmacodynamics With a New Oral Nicotine Replacement Therapy and Nicotine Gum April 2011 July 2011
NCT01408758 Completed N/A Virtual Clinician Research Tool January 2011 June 2012
NCT01423578 Completed N/A Effects of Yoga and Cardiovascular Exercise on Smoking Motivation August 21, 2007 June 20, 2017
NCT01428310 Completed Phase 1 Study to Evaluate the Safety and Efficacy of Dietary Supplement Anatabloc in Reducing Daily Smokers' Urge to Smoke September 2011 December 2011
NCT01440985 Completed N/A A Study on the Effects of Two Nicotine Replacement Products on Tooth Staining July 2005 November 2005
NCT01444131 Completed Phase 2 Varenicline in Combination With Nicotine Replacement Therapy for Smoking Cessation April 2011 June 2013
NCT01478230 Completed Early Phase 1 An Exploratory Study Comparing Two Nicotine Inhalers November 2011 December 2011
NCT01570595 Completed Phase 1/Phase 2 Positively Smoke Free on the Web (PSFW) for Smokers Living With HIV September 2011 September 2013
NCT01621009 Completed Phase 4 Bupropion SR Plus Counseling for Smoking Cessation January 2001 October 2003
NCT01621022 Completed Phase 4 Bupropion Alone or Combined With Nicotine Gum January 2001 October 2002
NCT01635075 Completed Phase 2 Acute Effects of Exercise in Smokers With Schizophrenia June 2012 January 2015
NCT01681875 Completed N/A Project 1, Study 1: Investigating the Impact of Nicotine Using Spectrum Cigarettes June 2013 July 2014
NCT01692730 Completed N/A Web Assisted Tobacco Intervention With Community Colleges October 2012 August 2016
NCT01735279 Completed Phase 3 Studying the Effects of Administration of Polyunsaturated Fatty Acids (PUFAS) of Omega-3 Series in Nicotine Dependence January 2013 March 2014
NCT01735448 Completed Improving Health for Aboriginal People Through Tobacco Related Research March 2013 April 2016
NCT01809678 Completed N/A Yoga as a Complementary Therapy for Smoking Cessation July 2012 June 2017
NCT01839903 Completed N/A System Based Tracking and Treatment for Emergency Patients Who Smoke: STTEPS August 19, 2011 June 30, 2017
NCT01882348 Completed N/A Changing Pediatric Office Systems Nationally to Address Parental Tobacco Use April 14, 2015 October 26, 2017
NCT06289192 Enrolling by invitation Phase 4 Testing C-Raven, a Virtual Tobacco Cessation Intervention, in the Community April 30, 2024 June 2025
NCT06218056 Not yet recruiting Phase 2 Cannabidiol for Reducing Cigarette Use July 15, 2024 December 31, 2026
NCT06170437 Not yet recruiting N/A Smoke-free Home Study in Subsidized Housing May 1, 2024 December 31, 2026
NCT06043362 Not yet recruiting N/A Use of Nicotine Pouches Among Daily Smokers June 2024 September 2028
NCT05429892 Recruiting N/A FRESH Delivers: An Innovative Approach to Reducing Tobacco Use Among Rural/Black African American Smokers August 9, 2023 September 30, 2026
NCT04001114 Recruiting N/A Cigarette Smoking in Smokers With and Without Schizophrenia July 15, 2021 December 2023
NCT04058717 Recruiting N/A Low Nicotine Cigarettes Plus Electronic Cigarettes June 1, 2021 May 2024
NCT05445804 Recruiting Phase 1 Oral Cannabidiol for Tobacco Cessation November 1, 2022 April 1, 2025
NCT05021185 Recruiting N/A Interactive Mobile Doctor (iMD) to Promote Tobacco Cessation Among Cancer Patients November 15, 2022 December 31, 2025
NCT05487807 Recruiting Phase 1 Adapting and Evaluating a Tobacco Use Cessation Program for People Living With HIV in Uganda and Zambia September 13, 2023 August 31, 2026
NCT05327660 Recruiting Phase 1/Phase 2 CO Monitoring for Tobacco Cessation in Quitlines December 31, 2021 November 1, 2022
NCT03905928 Recruiting N/A Establishing the Effect of Flavor on the Addictive Potential of Electronic Cigarettes November 4, 2019 June 30, 2024
NCT05829824 Recruiting N/A Tobacco Cessation Care for Cancer Patients by Automated Interactive Outreach November 27, 2023 June 30, 2024
NCT04832659 Recruiting N/A Assessment of Biomarkers in Children to Help Parents Quit Tobacco January 20, 2023 February 28, 2026
NCT03912194 Recruiting Phase 3 Early Withdrawal Exposure and Negative Affect Withdrawal (NAW) Regulation Training for Smoking Cessation August 1, 2019 June 24, 2026
NCT05836051 Recruiting N/A Testing the Effect of ENDS Flavors on Neurotransmission June 1, 2023 December 31, 2024
NCT03213418 Terminated N/A Electroretinogram: a New Human Biomarker for Smoking Cessation Treatment February 1, 2018 December 1, 2022
NCT02012452 Terminated N/A Tobacco Treatment as Augmentation for Cognitive Processing Therapy for PTSD December 2014 January 2016
NCT03507127 Terminated Phase 2 Targeted Pharmacological and Behavioral Treatments for Smoking in Schizophrenia Study 1 May 1, 2018 June 30, 2019
NCT00248118 Terminated Phase 2/Phase 3 Efficacy and Safety of Bupropion for Treatment of Adolescent Smoking January 2005 May 2008
NCT00521391 Terminated Phase 3 Physical Activity as an Aid for Smoking Cessation April 2003 December 2005
NCT01532232 Terminated Tobacco Dependence in Breast Cancer Patients Trial of Varenicline (Chantix) February 2012 October 2014
NCT01296698 Terminated Phase 3 Study to Determine if a New Nicotine Replacement Therapy Can Safely Help Smokers to Quit Smoking March 2011 June 2011
NCT00313105 Unknown status Phase 2/Phase 3 Smoking Cessation With Smokeless Tobacco, Nicotine Tablets and Nicotine Patches April 2006 August 2010
NCT00968513 Unknown status Phase 3 Evaluation of Tobacco Treatment Strategies for Inpatient Psychiatry September 2009 November 2015
NCT00977249 Unknown status Phase 2/Phase 3 Varenicline for Long-term Nicotine Replacement Therapy (NRT) Users September 2009 December 2011
NCT01494246 Unknown status Phase 4 Effectiveness of an E-mail Tracking Intervention Among the Continued Abstinence of Tobacco Consumption December 2012 December 2014
NCT04188197 Unknown status Phase 3 Assisting Smokers to Switch to a JUUL E-Cigarette by Devaluing Combustible Cigarettes August 26, 2019 December 15, 2020
NCT04265339 Unknown status N/A The Interplay Between Addiction to Tobacco Smoking and Sleep Quality Among Healthy Adults October 15, 2018 October 15, 2022
NCT01729507 Unknown status Phase 4 tDCS as Add on Therapy for Treatment of Tobacco Dependence by Standardized Behaviour Therapy July 2012 July 2013
NCT03249428 Unknown status N/A E-Cigarette Inner City RCT September 2019 September 2021
NCT01847300 Withdrawn N/A cSBI-M for Young Military Personnel September 2013 February 2017
NCT03113370 Withdrawn N/A Preventing Tobacco Relapse With Omega-3s Trial December 1, 2016 November 1, 2017
NCT05440721 Withdrawn N/A Clinical Trial of an Innovative Digital Therapeutic for Smoking Cessation With Biochemical Verification October 25, 2018 August 2022
NCT05625685 Withdrawn N/A Equitable Smoking Relapse Prevention October 2, 2023 November 30, 2023