Annotation Detail

Information
Associated Genes
CYP2E1
Associated Variants
CYP2E1 MUTATION
CYP2E1 MUTATION
Associated Disease
Slow acetylator due to N-acetyltransferase enzyme variant
Source Database
DisGeNET
Description
Most Moroccans are homozygous for c1 allele of CYP2E1 gene which aggravates hepatotoxicity in slow acetylators.
Pubmed
25544508
Section of the abstract supporting the evidence
CONCLUSION
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
9
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00190009310456212
Drugs