Annotation Detail

Information
Associated Genes
CYP2E1
Associated Variants
CYP2E1 MUTATION
CYP2E1 MUTATION
Associated Disease
tuberculosis
Source Database
DisGeNET
Description
The aim of this study was to determine, for the first time, the frequency of slow acetylators in Moroccan population by genotyping of NAT2 gene variants and determining the genotype c1/c1 for CYP2E1 gene, in order to predict adverse effects of Tuberculosis treatment, particularly hepatotoxicity.
Pubmed
25544508
Section of the abstract supporting the evidence
BACKGROUND
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
5
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.0124539885072915
Drugs