chr17:28521337:> Detail (hg19)

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Summary
Information
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Disease area statistics
MGeND
ClinVar
CIViC
DisGeNET
Annotation
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Information

Genome

Assembly	Position
hg19	chr17:28,521,337-28,563,020
hg38	chr17:30,194,319-30,236,002

HGVS

RefSeq

Type	Transcript	Protein

Summary

MGeND

Clinical significance
Variant entry
GWAS entry
Disease area statistics	Show details

Frequency

[No Data.]

Prediction

[No Data.]

ClinVar

Clinical Significance
Review star	[No Data.]
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Links

Disease area statistics

[No Data.]

MGeND

[No Data.]

ClinVar

[No Data.]

CIViC

[No Data.]

DisGeNET

Score	Disease name	Description	Source	Pubmed	Links
0.003	hypertrophic cardiomyopathy	NA	BeFree,GAD		Detail
0.008	Cardiovascular Diseases	NA	BeFree,GAD,LHGDN		Detail
<0.001	celiac disease	NA	BeFree		Detail
<0.001	CNS disorder	NA	BeFree		Detail
0.002	child abuse behavior	Our findings show that both the 5-HTTLPR S allele and maternal prenatal stress/c...	BeFree	24937096	Detail
0.002	child abuse behavior	Genetic moderation of child maltreatment effects on depression and internalizing...	BeFree	25422957	Detail
0.002	Chromosome Deletion	NA	GAD		Detail
<0.001	Cluster Headache	Bi-allelic and tri-allelic 5-HTTLPR polymorphisms and triptan non-response in cl...	BeFree	25043824	Detail
0.002	cocaine abuse	NA	GAD		Detail
0.120	Cognition Disorders	NA	CTD_human		Detail
<0.001	colitis	Serotonin (5-HT) release and serotonin reuptake transporter (5-HTT) expression h...	BeFree	25532499	Detail
0.003	ulcerative colitis	Association of Serotonin Transporter Promoter Polymorphism (5-HTTLPR) with Micro...	BeFree,LHGDN	25532499	Detail
<0.001	colorectal carcinoma	NA	BeFree		Detail
0.002	Connective Tissue Diseases	NA	GAD		Detail
0.003	Constipation	NA	BeFree,GAD		Detail
<0.001	Coronary Arteriosclerosis	NA	BeFree		Detail
0.003	Coronary heart disease	NA	BeFree,GAD		Detail
0.005	Deafness	NA	GAD		Detail
0.002	delusional disorder	NA	GAD		Detail
<0.001	Delusions	NA	BeFree		Detail
0.001	Presenile dementia	NA	BeFree		Detail
0.003	Dementia, Vascular	NA	BeFree,GAD		Detail
0.003	Dermatitis, Atopic	NA	BeFree,LHGDN		Detail
<0.001	Diabetes	NA	BeFree		Detail
<0.001	diabetes mellitus	NA	BeFree		Detail
0.003	Diabetes Mellitus, Non-Insulin-Dependent	Genetic association analysis of serotonin transporter polymorphism (5-HTTLPR) wi...	BeFree,GAD	25680681	Detail
0.003	diarrhea	NA	BeFree,GAD		Detail
0.003	diverticulitis	NA	BeFree,LHGDN		Detail
<0.001	Down syndrome	NA	BeFree		Detail
0.004	Drug abuse	The SS genotype of the serotonin transporter gene (5-HTTLPR) was associated with...	BeFree	25065374	Detail
0.004	Drug abuse	The SS genotype of 5-HTTLPR was associated with increased depression scores afte...	BeFree	25214390	Detail
0.004	Drug abuse	Our study included 2679 participants.Those with both the 5-HTTLPR s allele and t...	BeFree	25510949	Detail
0.001	Drug habituation	NA	BeFree		Detail
0.004	Dyspepsia	Association of SLC6A4 5-HTTLPR and TRPV1 945G>C with functional dyspepsia in Kor...	BeFree,GAD	24720453	Detail
0.004	Dyspepsia	Change in DNA methylation patterns of SLC6A4 gene in the gastric mucosa in funct...	BeFree,GAD	25148529	Detail
<0.001	dysthymic disorder	NA	BeFree		Detail
0.017	Eating Disorders	NA	BeFree,GAD		Detail
<0.001	eclampsia	To determine platelet serotonin (5-HT) concentrations and genotype and allele fr...	BeFree	25223859	Detail
<0.001	Eczema	NA	BeFree		Detail
<0.001	Emotional Disturbances	NA	BeFree		Detail
<0.001	endometriosis	NA	BeFree		Detail
<0.001	epilepsy	This study aimed to test whether a specific serotonin transporter (5HTT) gene po...	BeFree	25173097	Detail
0.014	Epilepsy, Temporal Lobe	NA	BeFree,GAD,LHGDN		Detail
0.011	Fatigue	NA	BeFree,GAD,LHGDN		Detail
0.010	chronic fatigue syndrome	NA	GAD,LHGDN		Detail
0.002	Fetal Death	NA	GAD		Detail
0.002	Fetal Diseases	NA	GAD		Detail
0.013	fibromyalgia	NA	BeFree,GAD,LHGDN		Detail
0.005	Gastrointestinal Diseases	NA	BeFree,GAD		Detail
0.002	Gingival Hemorrhage	NA	GAD		Detail
0.002	goiter	NA	GAD		Detail
0.005	Hallucinations	NA	BeFree,GAD		Detail
0.001	Headache	NA	BeFree		Detail
0.005	Hearing Loss, Partial	NA	GAD		Detail
0.005	Sensorineural Hearing Loss (disorder)	NA	GAD		Detail
<0.001	congenital heart defects	NA	BeFree		Detail
<0.001	Heart Diseases	NA	BeFree		Detail
0.003	Heart failure	NA	BeFree,GAD		Detail
<0.001	congestive heart failure	NA	BeFree		Detail
0.003	Atrial Septal Defects	Overall results of the study suggest that SLC6A4 markers have specific genetic e...	BeFree	25261775	Detail
0.003	Ventricular Septal Defects	NA	BeFree,GAD		Detail
<0.001	heart valve disease	NA	BeFree		Detail
0.005	hepatitis C	NA	BeFree,GAD		Detail
0.006	heroin dependence	NA	BeFree,GAD		Detail
<0.001	HIV Infections	NA	BeFree		Detail
<0.001	Hodgkin Disease	NA	BeFree		Detail
0.009	Huntington disease	Clinical features of Chinese patients with Huntington's disease carrying CAG rep...	BeFree	23398026	Detail
0.009	Huntington disease	In HD, the median expanded (CAG)n (range) was 44 (40-81) units; R(2) between exp...	BeFree	24102565	Detail
0.009	Huntington disease	Huntington disease (HD), an autosomal dominant disorder involving HTT, is charac...	BeFree	24405192	Detail
0.009	Huntington disease	Huntington disease (HD), the most common inherited cause of chorea, is an autoso...	BeFree	25034271	Detail
0.009	Huntington disease	Unintended weight loss, sleep and circadian disturbances and autonomic dysfuncti...	BeFree	25074766	Detail
0.009	Huntington disease	We postulate that the HD-related cardiomyopathy is caused by altered central aut...	BeFree	25101683	Detail
0.009	Huntington disease	Huntington's disease (HD) is a dominant neurodegenerative disorder that is due t...	BeFree	25645993	Detail
0.009	Huntington disease	We observed a diversity of HTT region haplotypes in both normal and expanded chr...	BeFree	25656686	Detail
0.009	Huntington disease	HTT acts as a modulator of HIP14 activity such that in the presence of the HD mu...	BeFree	25849918	Detail
0.009	Huntington disease	A SNP in the HTT promoter alters NF-κB binding and is a bidirectional genetic mo...	BeFree	25938884	Detail
0.009	Huntington disease	We first investigated tau pathology by looking for the presence of hyperphosphor...	BeFree	25953777	Detail
0.009	Huntington disease	As a Mendelian neurodegenerative disorder, the genetic risk of Huntington's dise...	BeFree	26232222	Detail
0.009	Huntington disease	Analysis of common SNP-based haplotypes has revealed that most European HD subje...	BeFree	26320893	Detail
0.009	Huntington disease	The causative gene (mutated HTT) is widely expressed outside the CNS and several...	BeFree	26466780	Detail
0.002	Hyperalgesia	NA	GAD		Detail
<0.001	Hyperphagia	NA	BeFree		Detail
0.011	Hypertensive disease	The results did not support the hypothesis that hypertension in pregnancy is a t...	BeFree,GAD,LHGDN	25223859	Detail
0.222	pulmonary hypertension	Chronic imetelstat treatment reduced hypoxia-induced PH in wild-type mice or par...	BeFree,CTD_human,GAD,LHGDN,RGD	25550449	Detail
0.005	Disruptive, Impulse Control, and Conduct Disorders	NA	GAD		Detail
0.005	Inflammation	NA	GAD		Detail
0.003	Inflammatory Bowel Diseases	NA	LHGDN		Detail
0.002	Sleep Initiation and Maintenance Disorders	NA	GAD		Detail
0.046	irritable bowel syndrome	NA	BeFree,GAD,LHGDN		Detail
0.002	Obstetric Labor Complications	NA	GAD		Detail
<0.001	Language Delay	NA	BeFree		Detail
0.003	Leukodystrophy, Metachromatic	NA	LHGDN		Detail
0.002	liver cirrhosis	NA	GAD		Detail
0.002	Liver Cirrhosis, Alcoholic	NA	GAD		Detail
<0.001	Liver neoplasms	The 5-HTT gene expression was almost silenced in chicken lymphoma DT40, myelomon...	BeFree	26024595	Detail
0.009	Chronic Obstructive Airway Disease	NA	BeFree,GAD,LHGDN		Detail
0.001	Lupus Erythematosus, Systemic	A 5-HTTLPR × SLEs interaction emerged, such that children homozygous for the sho...	BeFree	24117502	Detail
0.001	Lupus Erythematosus, Systemic	In light of continuing disagreement, even at the meta-analytic level, as to whet...	BeFree	24708477	Detail
0.002	lupus nephritis	NA	GAD		Detail
<0.001	lymphoma	The 5-HTT gene expression was almost silenced in chicken lymphoma DT40, myelomon...	BeFree	26024595	Detail
0.002	Single major depressive episode	Variants in the indel promoter region of the SLC6A4 gene have a more robust effe...	BeFree	23973251	Detail
0.002	Single major depressive episode	Genetic monitoring revealed that mRNA expression of SLC6A4/5HTT increased with t...	BeFree	24620999	Detail
0.002	Single major depressive episode	Seventy-four women (43 non-menopausal and 31 menopausal) and 29 men with a major...	BeFree	25257397	Detail
0.002	Single major depressive episode	We tested the effects of 5-HTTLPR on diffusion tensor imaging (DTI) measures of ...	BeFree	25704032	Detail
0.002	Malignant Carcinoid Syndrome	NA	GAD		Detail
0.002	Animal Mammary Neoplasms	NA	GAD		Detail
0.001	Marijuana Abuse	NA	BeFree		Detail
0.001	Melancholia	NA	BeFree		Detail
0.122	Memory Disorders	NA	CTD_human,GAD		Detail
0.005	Mental Retardation	NA	GAD		Detail
0.002	Musculoskeletal Diseases	NA	GAD		Detail
0.015	myocardial infarction	NA	BeFree,GAD,LHGDN		Detail
0.005	Nausea	NA	GAD		Detail
0.003	neurodermatitis	NA	BeFree,GAD		Detail
0.002	nicotine dependence	NA	BeFree		Detail
0.020	obesity	Small differences were observed in obesity indicators among three groups of pati...	BeFree,GAD	25486590	Detail
0.020	obesity	No significant statistical association of 5-HTTLPR polymorphism with type 2 diab...	BeFree,GAD	25680681	Detail
0.020	obesity	Association of VNTR polymorphisms in DRD4, 5-HTT and DAT1 genes with obesity.	BeFree,GAD	25687785	Detail
0.176	obsessive-compulsive disorder	We conclude that the 5-HTTLPR is currently the single best supported risk varian...	BeFree,CTD_human,GAD,LHGDN	25093702	Detail
0.176	obsessive-compulsive disorder	Is serotonin transporter polymorphism (5-HTTLPR) allele status a predictor for o...	BeFree,CTD_human,GAD,LHGDN	25896187	Detail
0.002	Occupational Diseases	NA	GAD		Detail
0.002	opioid abuse	NA	GAD		Detail
<0.001	oppositional defiant disorder	NA	BeFree		Detail
0.008	osteochondritis dissecans	NA	BeFree		Detail
0.003	Pain	The 5-HTTLPR polymorphism is associated with the susceptibility to TN and pain s...	BeFree,GAD	24950698	Detail
<0.001	Pain, Postoperative	NA	BeFree		Detail
0.045	panic disorder	NA	BeFree,GAD,LHGDN		Detail
0.017	Parkinson disease	Association between 5-HTTLPR polymorphism and Parkinson's disease: a meta analys...	BeFree,GAD,LHGDN	24972569	Detail
<0.001	Paroxysmal atrial tachycardia	NA	BeFree		Detail
0.002	Gambling, Pathological	NA	GAD		Detail
0.002	Periodontal Pocket	NA	GAD		Detail
0.002	periodontitis	NA	GAD		Detail
0.147	Personality Disorders	NA	BeFree,CTD_human,GAD		Detail
<0.001	Pituitary Diseases	NA	BeFree		Detail
0.002	Postoperative Complications	NA	GAD		Detail
0.002	Pregnancy Complications	NA	GAD		Detail
0.002	Pregnancy Complications, Hematologic	NA	GAD		Detail
<0.001	Pregnancy in Diabetics	NA	BeFree		Detail
0.005	premature ejaculation	Here, we evaluated the relationship between a polymorphism in the serotonin tran...	BeFree,GAD	25518026	Detail
0.005	Premenstrual syndrome	NA	GAD		Detail
0.002	Prenatal Exposure Delayed Effects	NA	GAD		Detail
<0.001	Primary Insomnia	NA	BeFree		Detail
0.003	psoriasis	NA	BeFree,GAD		Detail
0.002	Tension Headache	NA	GAD		Detail
0.002	Psychophysiologic Disorders	NA	GAD		Detail
0.002	Psychoses, Alcoholic	NA	GAD		Detail
0.005	Psychoses, Substance-Induced	NA	GAD		Detail
0.002	Puerperal Disorders	NA	GAD		Detail
0.003	Pulmonary Veno-Occlusive Disease (disorder)	NA	LHGDN		Detail
0.002	Raynaud disease	NA	GAD		Detail
0.002	schizoaffective disorder	NA	GAD		Detail
0.229	schizophrenia	No association of SLC6A3 and SLC6A4 gene polymorphisms with schizophrenia in the...	BeFree,CTD_human,GAD,LHGDN	25019689	Detail
0.003	systemic scleroderma	NA	BeFree,GAD		Detail
0.002	Sclerosis	NA	GAD		Detail
<0.001	organic sexual dysfunction	NA	BeFree		Detail
0.003	Dermatologic disorders	NA	BeFree,GAD		Detail
0.002	Skin Ulcer	NA	GAD		Detail
0.003	Sleep Apnea Syndromes	NA	LHGDN		Detail
0.001	Sleep disturbances	Instead, based on current and previous findings, it is suggested that the S'/S' ...	BeFree	25644221	Detail
0.002	Speech Disorders	NA	GAD		Detail
0.005	aphthous stomatitis	NA	GAD,LHGDN		Detail
0.002	Stress	NA	GAD		Detail
0.017	post-traumatic stress disorder	An examination of the association between 5-HTTLPR, combat exposure, and PTSD di...	BeFree,GAD	25793742	Detail
0.007	Stress, Psychological	The 5-HTTLPR polymorphism, early and recent life stress, and cognitive endopheno...	BeFree	24433089	Detail
0.007	Stress, Psychological	The serotonin transporter (SERT) gene-linked polymorphic region (5-HTTLPR) has b...	BeFree	24937096	Detail
0.007	Stress, Psychological	This study aimed to test whether a specific serotonin transporter (5HTT) gene po...	BeFree	25173097	Detail
0.007	Stress, Psychological	5-HTTLPR modulated the relationship between early life stress and the core featu...	BeFree	25219494	Detail
0.007	Stress, Psychological	Although 5-HTTLPR has been shown to influence the risk of life stress-induced de...	BeFree	25747798	Detail
0.007	Cerebrovascular accident	The 5-HTTLPR short allele was associated with suicidal ideation 2 weeks after st...	BeFree,GAD	23973249	Detail
0.002	substance dependence	Characterization of serotonin transporter gene (SLC6A4) polymorphisms and its as...	BeFree	23033208	Detail
0.001	Substance Use Disorders	NA	BeFree		Detail
0.127	Substance Withdrawal Syndrome	NA	BeFree,CTD_human,GAD		Detail
0.226	sudden infant death syndrome	NA	BeFree,CTD_human,GAD,LHGDN,MGD		Detail
0.002	Thinness	NA	GAD		Detail
0.007	Tobacco use disorder	NA	GAD		Detail
0.005	Gilles de la Tourette syndrome	NA	BeFree,GAD		Detail
<0.001	trigeminal neuralgia	To investigate the possible association between the serotonin transporter gene (...	BeFree	24950698	Detail
0.007	Attention Deficit Disorder	NA	GAD		Detail
0.002	Adverse reaction to drug	NA	GAD		Detail
<0.001	Vascular Diseases	NA	BeFree		Detail
0.005	Vasovagal syncope	NA	GAD		Detail
<0.001	Violence	In the current study, we aimed to investigate the contribution of serotonin tran...	BeFree	24890444	Detail
<0.001	Violence	Lack of association between the 5-HTTLPR and positive screening for mental disor...	BeFree	25517418	Detail
0.002	Vomiting	NA	GAD		Detail
0.007	Weight Gain	NA	GAD		Detail
<0.001	severe combined immunodeficiency	NA	BeFree		Detail
0.006	seasonal affective disorder	Therefore, effects of 5-HTTLPR might be buffered by high social support with res...	BeFree,GAD	24407753	Detail
<0.001	Hypoalgesia	NA	BeFree		Detail
0.003	Agitation	NA	BeFree,GAD		Detail
<0.001	Mood swings	NA	BeFree		Detail
0.031	Alcohol abuse	NA	BeFree,GAD		Detail
0.003	Depressive Syndrome	NA	BeFree,GAD		Detail
<0.001	Panic Attacks	NA	BeFree		Detail
<0.001	Withdrawal Symptoms	NA	BeFree		Detail
0.013	conduct disorder	NA	BeFree,GAD,LHGDN		Detail
0.003	Left Ventricular Hypertrophy	NA	BeFree,GAD		Detail
<0.001	somatization	NA	BeFree		Detail
0.038	Migraine Disorders	NA	BeFree,GAD,LHGDN		Detail
0.001	Chronic pain	NA	BeFree		Detail
0.007	Premature Birth	NA	GAD		Detail
0.005	lingual-facial-buccal dyskinesia	NA	BeFree,GAD		Detail
<0.001	Drug withdrawal syndrome	NA	BeFree		Detail
0.003	Idiopathic pulmonary hypertension	NA	BeFree		Detail
<0.001	atypical depressive disorder	NA	BeFree		Detail
0.002	Rumination Disorders	NA	GAD		Detail
0.014	migraine with aura	NA	BeFree,GAD,LHGDN		Detail
<0.001	acute myocardial infarction	NA	BeFree		Detail
0.003	Arthralgia of temporomandibular joint	NA	BeFree,GAD		Detail
0.002	Periodontal Attachment Loss	NA	GAD		Detail
0.002	Amyloid Neuropathies, Familial	NA	GAD		Detail
<0.001	Lip and oral cavity carcinoma	NA	BeFree		Detail
0.005	Depression, Postpartum	NA	BeFree,GAD		Detail
<0.001	Recurrent depression	NA	BeFree		Detail
<0.001	Chronic abdominal pain	NA	BeFree		Detail
<0.001	Psychological symptom	NA	BeFree		Detail
<0.001	Psychiatric symptom	There was no positive correlation between the 5-HTTLPR polymorphism and presence...	BeFree	25517418	Detail
<0.001	Dysphoric mood	NA	BeFree		Detail
0.004	Antisocial behavior	The differential susceptibility theory was examined by investigating the presenc...	BeFree	24929324	Detail
<0.001	Negativism in catatonia	NA	BeFree		Detail
0.003	Memory impairment	NA	BeFree,GAD		Detail
0.050	Personality Traits	NA	GAD		Detail
<0.001	Pick Disease of the Brain	Functional genetic variation in the serotonin 5-HTTLPR modulates brain damage in...	BeFree	25128279	Detail
0.003	Alcohol withdrawal syndrome	NA	BeFree,GAD		Detail
0.005	Alcohol-Related Disorders	NA	GAD		Detail
0.122	Amphetamine-Related Disorders	NA	CTD_human,GAD		Detail
0.120	Cocaine-Related Disorders	NA	CTD_human		Detail
<0.001	Bipolar II disorder	NA	BeFree		Detail
0.120	Asperger syndrome	NA	CTD_human		Detail
<0.001	Panic disorder with agoraphobia	We determined whether the 5-HTTLPR genotype predicted change in avoidance behavi...	BeFree	24906789	Detail
<0.001	Panic disorder with agoraphobia	Therapygenetics: anterior cingulate cortex-amygdala coupling is associated with ...	BeFree	25223844	Detail
<0.001	Stress Disorders, Traumatic, Acute	NA	BeFree		Detail
0.134	Substance-Related Disorders	NA	CTD_human,GAD		Detail
0.001	Alcohol or Other Drugs use	NA	BeFree		Detail
0.009	Physiological Sexual Disorders	NA	GAD		Detail
0.080	Parkinsonian Disorders	NA	RGD		Detail
<0.001	Drug usage	NA	BeFree		Detail
0.002	multiple chemical sensitivity	NA	GAD		Detail
<0.001	anxiety generalized	NA	BeFree		Detail
<0.001	generalized anxiety disorder	NA	BeFree		Detail
<0.001	Generalized social phobia	NA	BeFree		Detail
<0.001	Spastic syndrome	Many reports suggests roles of N-terminal 17 amino acid domain of HTT (HTT-N17) ...	BeFree	25446099	Detail
<0.001	Cancer of Head and Neck	NA	BeFree		Detail
<0.001	Expressed Emotion	The differential susceptibility theory was examined by investigating the presenc...	BeFree	24929324	Detail
<0.001	frontotemporal dementia	Functional genetic variation in the serotonin 5-HTTLPR modulates brain damage in...	BeFree	25128279	Detail
0.003	Common Migraine	NA	BeFree,LHGDN		Detail
0.001	Impaired cognition	Huntington disease (HD), an autosomal dominant disorder involving HTT, is charac...	BeFree	24405192	Detail
0.001	Manic	NA	BeFree		Detail
0.002	Mixed anxiety and depressive disorder	NA	BeFree		Detail
<0.001	Irritable bowel syndrome with diarrhea	NA	BeFree		Detail
0.003	Nonorganic psychosis	NA	BeFree		Detail
0.001	Depressive episode, unspecified	Using data from the 1993 Pelotas Birth Cohort Study, and adopting a design as si...	BeFree	26315979	Detail
<0.001	Phobic anxiety disorder	NA	BeFree		Detail
<0.001	Ischemic cardiomyopathy	NA	BeFree		Detail
0.002	Cardiac Death	NA	GAD		Detail
<0.001	Diagnosis, Psychiatric	NA	BeFree		Detail
0.003	Chronic tension-type headache	NA	BeFree,GAD		Detail
<0.001	Colitis, Microscopic	Association of Serotonin Transporter Promoter Polymorphism (5-HTTLPR) with Micro...	BeFree	25532499	Detail
<0.001	Anxiety and fear	NA	BeFree		Detail
<0.001	Social fear	NA	BeFree		Detail
0.002	Response to pain finding	NA	GAD		Detail
<0.001	Motor symptoms	NA	BeFree		Detail
0.006	Ichthyosis bullosa of Siemens	NA	BeFree		Detail
<0.001	Performance anxiety	NA	BeFree		Detail
<0.001	Peripheral neuropathic pain	NA	BeFree		Detail
0.009	dementia	NA	BeFree,GAD,LHGDN		Detail
0.006	Overweight	NA	BeFree,GAD		Detail
0.011	Sleep Apnea, Obstructive	NA	BeFree,GAD,LHGDN		Detail
<0.001	Symptoms of stress	NA	BeFree		Detail
<0.001	Pervasive Development Disorder	NA	BeFree		Detail
0.003	Metabolic syndrome X	NA	BeFree,GAD		Detail
0.002	Neurodegenerative Disorders	Huntington's disease (HD) is a dominant neurodegenerative disorder that is due t...	BeFree	25645993	Detail
0.005	Mercury Poisoning, Nervous System	NA	GAD		Detail
<0.001	Alcohol problem	The purpose of the present study was to examine whether a cumulative genetic sco...	BeFree	24759925	Detail
<0.001	sexual dysfunction	NA	BeFree		Detail
<0.001	Functional Gastrointestinal Disorders	NA	BeFree		Detail
<0.001	Maternal hypertension	The results did not support the hypothesis that hypertension in pregnancy is a t...	BeFree	25223859	Detail
<0.001	Chronic depression	NA	BeFree		Detail
<0.001	Alcohol Withdrawal Seizures	NA	BeFree		Detail
<0.001	Severe depression	NA	BeFree		Detail
0.155	Mental Depression	The low activity variants of the 5-HTT-linked polymorphic region in the serotoni...	BeFree	19339052	Detail
0.021	Depressive Symptoms	The BDNF Val(66)Met x 5-HTTLPR x child adversity interaction and depressive symp...	BeFree	17579366	Detail
0.282	depressive disorder	Higher order interaction effects involving BDNF Val(66)Met, 5-HTTLPR and childho...	BeFree	17579366	Detail
0.007	Stress, Psychological	These results suggest that both 5-HTTLPR and BDNF Val66Met moderate the relation...	BeFree	21745335	Detail
0.226	bipolar disorder	These results suggest that BDNF G196A as well as 5HTT-LPR polymorphisms confer r...	BeFree	18657242	Detail
0.155	Mental Depression	5-HTTLPR and BDNF Val66Met polymorphisms and response to rTMS treatment in drug ...	BeFree	18450378	Detail
0.282	depressive disorder	5-HTTLPR and BDNF Val66Met polymorphisms and response to rTMS treatment in drug ...	BeFree	18450378	Detail
0.015	Mental disorders	Using clinical data and DNA samples from mouthwash gathered from an epidemiologi...	BeFree	24683520	Detail
0.029	Psychotic Disorders	Association of 5-HTTLPR serotonin transporter gene polymorphism and Val66Met bra...	BeFree	19526102	Detail
0.031	NEUROTICISM	BDNF Val66Met is associated with introversion and interacts with 5-HTTLPR to inf...	BeFree	20042999	Detail
0.155	Mental Depression	Polymorphisms in BDNF (Val66Met) and 5-HTTLPR, morning cortisol and subsequent d...	BeFree	21037213	Detail
0.188	Mood Disorders	In the present study, we evaluated the impact of the BDNF Val66Met polymorphism ...	BeFree	17392738	Detail
<0.001	alcohol use disorder	This study aimed to investigate the association of alcohol use disorder (AUD) wi...	BeFree	19637400	Detail
0.003	Premenstrual dysphoric disorder	The 5-HTT linked polymorphic region (5-HTTLPR) and BDNF Val66Met polymorphisms w...	BeFree	24615932	Detail
0.021	Depressive Symptoms	The serotonin transporter polymorphism (5-HTTLPR) and the brain-derived neurotro...	BeFree	21420735	Detail
<0.001	Delinquent behavior	Functional variants of the MAOA-uVNTR, 5-HTTLPR, and BDNF Val66Met, either alone...	BeFree	25522433	Detail
0.002	Sexual abuse	Further, the two genotype combinations that differed the most in expression leve...	BeFree	25522433	Detail
0.021	Depressive Symptoms	Both 5-HTTLPR and BDNF Val66Met interacted with unfavourable environment in rela...	BeFree	23481907	Detail
0.029	Psychotic Disorders	Using clinical data and DNA samples from mouthwash gathered from an epidemiologi...	BeFree	24683520	Detail
0.004	Drug abuse	Genetic epistasis between the brain-derived neurotrophic factor Val66Met polymor...	BeFree	21996278	Detail
0.282	depressive disorder	Genetic epistasis between the brain-derived neurotrophic factor Val66Met polymor...	BeFree	21996278	Detail
0.021	Depressive Symptoms	The low activity variants of the 5-HTT-linked polymorphic region in the serotoni...	BeFree	19339052	Detail
0.021	Depressive Symptoms	BDNF Val 66 Met and 5-HTTLPR genotype moderate the impact of early psychosocial ...	BeFree	23058261	Detail
0.188	Mood Disorders	Further investigations in larger samples are needed to clarify the usefulness of...	BeFree	18450378	Detail
0.282	depressive disorder	Polymorphisms in BDNF (Val66Met) and 5-HTTLPR, morning cortisol and subsequent d...	BeFree	21037213	Detail
0.282	depressive disorder	The low activity variants of the 5-HTT-linked polymorphic region in the serotoni...	BeFree	19339052	Detail
0.005	Depression, Postpartum	The present study is aimed to examine whether functional polymorphic variants, B...	BeFree	21997575	Detail
0.282	depressive disorder	Associations between suicidal ideation and 5-HTTLPR, STin2 VNTR, 5-HTR2a 1438A/G...	BeFree	23973249	Detail
0.155	Mental Depression	Associations between suicidal ideation and 5-HTTLPR, STin2 VNTR, 5-HTR2a 1438A/G...	BeFree	23973249	Detail
0.009	dementia	The aim of this study was to investigate the association of a serotonin transpor...	BeFree	15000807	Detail
0.038	Migraine Disorders	Association analysis of 5-HTTLPR variants, 5-HT2a receptor gene 102T/C polymorph...	BeFree	14668201	Detail
0.004	Psychotic symptom	The aim of this study was to investigate the association of a serotonin transpor...	BeFree	15000807	Detail
0.021	Depressive Symptoms	The aim of this study was to investigate the role of serotonin in depression, se...	BeFree	17183148	Detail
0.003	Nonorganic psychosis	No significant differences in the distribution of allele and genotype frequencie...	BeFree	17614196	Detail
0.029	Psychotic Disorders	No significant differences in the distribution of allele and genotype frequencie...	BeFree	17614196	Detail
0.001	Presenile dementia	The aim of this study was to investigate the association of a serotonin transpor...	BeFree	15000807	Detail
0.005	Gilles de la Tourette syndrome	As neuroimaging studies allude to dopaminergic and serotonergic dysfunction in G...	BeFree	20010450	Detail
<0.001	Obsessive compulsive behavior	NA	BeFree		Detail
<0.001	Hot flushes	This is the first study to test the association between HFs in both European-Ame...	BeFree	25026114	Detail
0.005	Heroin Abuse	NA	BeFree,GAD		Detail
0.006	cocaine dependence	NA	BeFree,GAD		Detail
0.002	hepatopulmonary syndrome	NA	GAD		Detail
<0.001	Hashimoto Disease	NA	BeFree		Detail
0.001	Emotional problems	NA	BeFree		Detail
0.001	breast carcinoma	NA	BeFree		Detail
<0.001	physical symptom	NA	BeFree		Detail
<0.001	hazardous drinking	NA	BeFree		Detail
0.003	Tardive Dyskinesia	NA	BeFree,GAD		Detail
<0.001	heavy drinking	5-HTTLPR moderates naltrexone and psychosocial treatment responses in heavy drin...	BeFree	25070809	Detail
<0.001	Dyssomnias	Instead, based on current and previous findings, it is suggested that the S'/S' ...	BeFree	25644221	Detail
<0.001	Emotional distress	NA	BeFree		Detail
0.002	Slow transit constipation	NA	GAD		Detail
<0.001	Emotional abuse	The SS genotype of the serotonin transporter gene (5-HTTLPR) was associated with...	BeFree	25065374	Detail
<0.001	ABUSE NEGLECT	There was no positive correlation between the 5-HTTLPR polymorphism and presence...	BeFree	25517418	Detail
0.003	Substance abuse problem	NA	BeFree,GAD		Detail
<0.001	cardiac event	NA	BeFree		Detail
<0.001	Paranoid ideation	NA	BeFree		Detail
<0.001	Learning Disabilities	NA	BeFree		Detail
<0.001	psychological distress	NA	BeFree		Detail
<0.001	thrombocytosis	NA	BeFree		Detail
0.008	Sleep Disorders	Instead, based on current and previous findings, it is suggested that the S'/S' ...	BeFree,GAD	25644221	Detail
<0.001	Completed Suicide	NA	BeFree		Detail
<0.001	placental choriocarcinoma	NA	BeFree		Detail
<0.001	Autistic behavior	NA	BeFree		Detail
<0.001	Childhood aggression	NA	BeFree		Detail
0.002	Anxiety symptoms	NA	GAD		Detail
<0.001	Adult attention deficit hyperactivity disorder	NA	BeFree		Detail
0.004	Psychotic symptom	NA	BeFree,GAD		Detail
0.001	social stress	Two hundred healthy adults were exposed to a laboratory stressor (Trier Social S...	BeFree	25226552	Detail
0.001	social stress	Maternal behavior and infant 5-HTTLPR polymorphism have been linked to infants' ...	BeFree	25676184	Detail
0.002	Sleep Disorders, Circadian Rhythm	NA	GAD		Detail
<0.001	Cardiomyopathies	We postulate that the HD-related cardiomyopathy is caused by altered central aut...	BeFree	25101683	Detail
<0.001	Sleeplessness	Interaction between serotonin transporter gene-linked polymorphic region (5-HTTL...	BeFree	25154585	Detail
0.002	Ischemic stroke	NA	GAD		Detail
<0.001	Acute coronary syndrome	ACS patients with the 5-HTTLPR s allele are thus potentially susceptible to depr...	BeFree	25772786	Detail
0.002	coronary restenosis	NA	GAD		Detail
<0.001	Tauopathies	We first investigated tau pathology by looking for the presence of hyperphosphor...	BeFree	25953777	Detail
0.082	attention deficit hyperactivity disorder	The serotonin transporter gene polymorphism 5-HTTLPR moderates the effects of st...	BeFree,GAD,LHGDN	24797917	Detail
0.082	attention deficit hyperactivity disorder	The differential susceptibility theory was examined by investigating the presenc...	BeFree,GAD,LHGDN	24929324	Detail
0.082	attention deficit hyperactivity disorder	Brain Correlates of the Interaction Between 5-HTTLPR and Psychosocial Stress Med...	BeFree,GAD,LHGDN	25998280	Detail
0.005	hearing impairment	NA	GAD		Detail
<0.001	Cardiac fibrosis	NA	BeFree		Detail
<0.001	Severe diarrhea	NA	BeFree		Detail
<0.001	Methamphetamine abuse	NA	BeFree		Detail
0.002	Mammary Neoplasms	NA	GAD		Detail
0.001	drug dependence	Characterization of serotonin transporter gene (SLC6A4) polymorphisms and its as...	BeFree	23033208	Detail
0.002	Autism Spectrum Disorders	NA	BeFree		Detail
0.001	Depression and Suicide	NA	BeFree		Detail
0.003	colorectal cancer	NA	BeFree,GAD		Detail
<0.001	Methamphetamine dependence	NA	BeFree		Detail
0.002	Cirrhosis	NA	GAD		Detail
0.009	Suicidal behavior	NA	GAD		Detail
<0.001	Opitz-G syndrome, type 2	NA	BeFree		Detail
0.010	MAJOR AFFECTIVE DISORDER 2	NA	BeFree,GAD		Detail
0.031	NEUROTICISM	Although high neuroticism was significantly related to a higher frequency of str...	BeFree,GAD	25644221	Detail
0.031	NEUROTICISM	A functional polymorphism (5-HTTLPR) within the serotonin transporter gene (SERT...	BeFree,GAD	25711941	Detail
<0.001	COGNITIVE FUNCTION 1, SOCIAL	NA	BeFree		Detail
0.006	MAJOR AFFECTIVE DISORDER 1	NA	BeFree,GAD		Detail
0.005	PANIC DISORDER 1	NA	BeFree		Detail
<0.001	Transformed migraine	NA	BeFree		Detail
0.006	MAJOR AFFECTIVE DISORDER 4	NA	BeFree,GAD		Detail
0.006	MAJOR AFFECTIVE DISORDER 5	NA	BeFree,GAD		Detail
0.006	MAJOR AFFECTIVE DISORDER 6	NA	BeFree,GAD		Detail
<0.001	Depressive Disorder, Treatment-Resistant	Serotonin transporter (5-HTTLPR) and norepinephrine transporter (NET) gene polym...	BeFree	25650523	Detail
<0.001	liver carcinoma	The 5-HTT gene expression was almost silenced in chicken lymphoma DT40, myelomon...	BeFree	26024595	Detail
0.004	bulimia nervosa	NA	BeFree,LHGDN		Detail
<0.001	clinical depression	NA	BeFree		Detail
0.006	Major affective disorder 7	NA	BeFree,GAD		Detail
0.006	MAJOR AFFECTIVE DISORDER 8	NA	BeFree,GAD		Detail
0.006	MAJOR AFFECTIVE DISORDER 9	NA	BeFree,GAD		Detail
0.007	Weight Loss Adverse Event	NA	GAD		Detail
0.007	Weight Gain Adverse Event	NA	GAD		Detail
0.001	Pulmonary arterial hypertension	NA	BeFree		Detail
0.002	Idiopathic pulmonary arterial hypertension	NA	BeFree		Detail
0.002	Infection	NA	GAD		Detail
<0.001	intellectual disability	NA	BeFree		Detail
0.001	Pulmonary hypertension, primary, 1, with hereditary hemorrhagic telangiectasia	NA	BeFree		Detail
0.002	Loneliness in adolescence	NA	GAD		Detail
<0.001	Depression in children	NA	BeFree		Detail
0.002	Psychomotor Agitation	NA	GAD		Detail
0.005	Hearing Loss	NA	GAD		Detail
0.008	Affective Disorders, Psychotic	NA	BeFree,GAD		Detail
<0.001	Affective Symptoms	NA	BeFree		Detail
<0.001	agoraphobia	Therapygenetics: 5-HTTLPR genotype predicts the response to exposure therapy for...	BeFree	24906789	Detail
<0.001	alcohol use disorder	NA	BeFree		Detail
0.003	Alcohol Withdrawal Delirium	NA	BeFree,GAD		Detail
0.003	alexithymia	NA	BeFree,GAD		Detail
0.058	Alzheimer's disease	Abnormal expression and genetic polymorphism of SLC6A3 and SLC6A4 genes may incr...	BeFree,GAD,LHGDN	25019689	Detail
0.003	retrograde amnesia	NA	BeFree,GAD		Detail
0.002	Angina Pectoris	NA	GAD		Detail
<0.001	Anorexia	NA	BeFree		Detail
0.022	anorexia nervosa	The 5-HTTLPR confers susceptibility to anorexia nervosa in Han Chinese: evidence...	BeFree,GAD,LHGDN	25785698	Detail
0.080	Anoxia	NA	RGD		Detail
0.005	antisocial personality disorder	NA	BeFree,GAD		Detail
0.005	Anxiety	NA	GAD		Detail
0.264	Anxiety Disorders	The reported interaction effects demonstrate that gender strongly modulates the ...	BeFree,CTD_human,GAD,RGD	23986266	Detail
0.264	Anxiety Disorders	Strong evidence links the 5-HTTLPR genotype to the modulation of amygdala reacti...	BeFree,CTD_human,GAD,RGD	25140050	Detail
0.264	Anxiety Disorders	Neither the treatment nor the reduced fMRI sample showed a direct effect of 5-HT...	BeFree,CTD_human,GAD,RGD	25223844	Detail
0.264	Anxiety Disorders	To ascertain whether genetic variations in the serotonin transporter gene (5-HTT...	BeFree,CTD_human,GAD,RGD	25517418	Detail
0.264	Anxiety Disorders	Evaluation of the relationship between 5-HTT and MAO gene polymorphisms, mood an...	BeFree,CTD_human,GAD,RGD	25547397	Detail
0.264	Anxiety Disorders	Selective serotonin reuptake inhibitors (SSRIs), such as citalopram, which selec...	BeFree,CTD_human,GAD,RGD	25745133	Detail
0.264	Anxiety Disorders	Albeit 5-HTTLPR has only weak/moderate effects, the s allele is directly associa...	BeFree,CTD_human,GAD,RGD	25747798	Detail
0.002	Cardiac arrhythmia	NA	GAD		Detail
0.033	As If Personality	NA	GAD		Detail
<0.001	Ataxia	NA	BeFree		Detail
0.003	atherosclerosis	NA	LHGDN		Detail
0.268	autistic disorder	SLC6A4 markers modulate platelet 5-HT level and specific behaviors of autism: a ...	BeFree,CTD_human,GAD,LHGDN,MGD	25261775	Detail
<0.001	Behavior Disorders	NA	BeFree		Detail
0.226	bipolar disorder	5-HTTLPR modulated the relationship between early life stress and the core featu...	BeFree,CTD_human,GAD,LHGDN	25219494	Detail
0.226	bipolar disorder	A total of sixty-three genetic variants were selected on the basis of previous G...	BeFree,CTD_human,GAD,LHGDN	25517604	Detail
0.226	bipolar disorder	White matter microstructure in bipolar disorder is influenced by the serotonin t...	BeFree,CTD_human,GAD,LHGDN	25704032	Detail
<0.001	Depression, Bipolar	NA	BeFree		Detail
<0.001	Blushing	NA	BeFree		Detail
0.005	borderline personality disorder	NA	BeFree,GAD		Detail
<0.001	Brain Diseases	NA	BeFree		Detail
0.004	Malignant neoplasm of breast	NA	BeFree,GAD		Detail
0.001	bronchopulmonary dysplasia	NA	BeFree		Detail
0.015	Bulimia	NA	BeFree,GAD,LHGDN		Detail
0.003	burning mouth syndrome	NA	BeFree,GAD		Detail

Annotation

Annotations

Descrption	Source	Links
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
Our findings show that both the 5-HTTLPR S allele and maternal prenatal stress/child maltreatment ar...	DisGeNET	Detail
Genetic moderation of child maltreatment effects on depression and internalizing symptoms by seroton...	DisGeNET	Detail
NA	DisGeNET	Detail
Bi-allelic and tri-allelic 5-HTTLPR polymorphisms and triptan non-response in cluster headache.	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
Serotonin (5-HT) release and serotonin reuptake transporter (5-HTT) expression have been reported to...	DisGeNET	Detail
Association of Serotonin Transporter Promoter Polymorphism (5-HTTLPR) with Microscopic Colitis and U...	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
Genetic association analysis of serotonin transporter polymorphism (5-HTTLPR) with type 2 diabetes p...	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
The SS genotype of the serotonin transporter gene (5-HTTLPR) was associated with high levels of impu...	DisGeNET	Detail
The SS genotype of 5-HTTLPR was associated with increased depression scores after childhood abuse on...	DisGeNET	Detail
Our study included 2679 participants.Those with both the 5-HTTLPR s allele and the BDNF Met allele s...	DisGeNET	Detail
NA	DisGeNET	Detail
Association of SLC6A4 5-HTTLPR and TRPV1 945G>C with functional dyspepsia in Korea.	DisGeNET	Detail
Change in DNA methylation patterns of SLC6A4 gene in the gastric mucosa in functional dyspepsia.	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
To determine platelet serotonin (5-HT) concentrations and genotype and allele frequencies of seroton...	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
This study aimed to test whether a specific serotonin transporter (5HTT) gene polymorphism interacti...	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
Overall results of the study suggest that SLC6A4 markers have specific genetic effect on individual ...	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
Clinical features of Chinese patients with Huntington's disease carrying CAG repeats beyond 60 withi...	DisGeNET	Detail
In HD, the median expanded (CAG)n (range) was 44 (40-81) units; R(2) between expanded HTT and age-at...	DisGeNET	Detail
Huntington disease (HD), an autosomal dominant disorder involving HTT, is characterized by chorea, p...	DisGeNET	Detail
Huntington disease (HD), the most common inherited cause of chorea, is an autosomal dominant disorde...	DisGeNET	Detail
Unintended weight loss, sleep and circadian disturbances and autonomic dysfunction are prevalent fea...	DisGeNET	Detail
We postulate that the HD-related cardiomyopathy is caused by altered central autonomic pathways alth...	DisGeNET	Detail
Huntington's disease (HD) is a dominant neurodegenerative disorder that is due to expansion of an un...	DisGeNET	Detail
We observed a diversity of HTT region haplotypes in both normal and expanded chromosomes, representa...	DisGeNET	Detail
HTT acts as a modulator of HIP14 activity such that in the presence of the HD mutation, HIP14 is les...	DisGeNET	Detail
A SNP in the HTT promoter alters NF-κB binding and is a bidirectional genetic modifier of Huntington...	DisGeNET	Detail
We first investigated tau pathology by looking for the presence of hyperphosphorylated tau aggregate...	DisGeNET	Detail
As a Mendelian neurodegenerative disorder, the genetic risk of Huntington's disease (HD) is conferre...	DisGeNET	Detail
Analysis of common SNP-based haplotypes has revealed that most European HD subjects have distinguish...	DisGeNET	Detail
The causative gene (mutated HTT) is widely expressed outside the CNS and several peripheral signs of...	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
The results did not support the hypothesis that hypertension in pregnancy is a trait associated with...	DisGeNET	Detail
Chronic imetelstat treatment reduced hypoxia-induced PH in wild-type mice or partially reversed esta...	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
The 5-HTT gene expression was almost silenced in chicken lymphoma DT40, myelomonocytic tumor HD11 an...	DisGeNET	Detail
NA	DisGeNET	Detail
A 5-HTTLPR × SLEs interaction emerged, such that children homozygous for the short allele were more ...	DisGeNET	Detail
In light of continuing disagreement, even at the meta-analytic level, as to whether the gene- × -env...	DisGeNET	Detail
NA	DisGeNET	Detail
The 5-HTT gene expression was almost silenced in chicken lymphoma DT40, myelomonocytic tumor HD11 an...	DisGeNET	Detail
Variants in the indel promoter region of the SLC6A4 gene have a more robust effect to antidepressant...	DisGeNET	Detail
Genetic monitoring revealed that mRNA expression of SLC6A4/5HTT increased with the emergence of a de...	DisGeNET	Detail
Seventy-four women (43 non-menopausal and 31 menopausal) and 29 men with a major depressive episode ...	DisGeNET	Detail
We tested the effects of 5-HTTLPR on diffusion tensor imaging (DTI) measures of WM microstructure in...	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
Small differences were observed in obesity indicators among three groups of patients with various ge...	DisGeNET	Detail
No significant statistical association of 5-HTTLPR polymorphism with type 2 diabetes and obesity in ...	DisGeNET	Detail
Association of VNTR polymorphisms in DRD4, 5-HTT and DAT1 genes with obesity.	DisGeNET	Detail
We conclude that the 5-HTTLPR is currently the single best supported risk variant for OCD, in regard...	DisGeNET	Detail
Is serotonin transporter polymorphism (5-HTTLPR) allele status a predictor for obsessive-compulsive ...	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
The 5-HTTLPR polymorphism is associated with the susceptibility to TN and pain severity of TN.	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
Association between 5-HTTLPR polymorphism and Parkinson's disease: a meta analysis.	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
Here, we evaluated the relationship between a polymorphism in the serotonin transporter gene-linked ...	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
No association of SLC6A3 and SLC6A4 gene polymorphisms with schizophrenia in the Han Chinese populat...	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
Instead, based on current and previous findings, it is suggested that the S'/S' 5-HTTLPR genotype pr...	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
An examination of the association between 5-HTTLPR, combat exposure, and PTSD diagnosis among U.S. v...	DisGeNET	Detail
The 5-HTTLPR polymorphism, early and recent life stress, and cognitive endophenotypes of depression.	DisGeNET	Detail
The serotonin transporter (SERT) gene-linked polymorphic region (5-HTTLPR) has been implicated in mo...	DisGeNET	Detail
This study aimed to test whether a specific serotonin transporter (5HTT) gene polymorphism interacti...	DisGeNET	Detail
5-HTTLPR modulated the relationship between early life stress and the core features of bipolar illne...	DisGeNET	Detail
Although 5-HTTLPR has been shown to influence the risk of life stress-induced depression in the majo...	DisGeNET	Detail
The 5-HTTLPR short allele was associated with suicidal ideation 2 weeks after stroke, although the s...	DisGeNET	Detail
Characterization of serotonin transporter gene (SLC6A4) polymorphisms and its association with drug ...	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
To investigate the possible association between the serotonin transporter gene (5-HTTLPR) and rs 255...	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
In the current study, we aimed to investigate the contribution of serotonin transporter (5-HTT) poly...	DisGeNET	Detail
Lack of association between the 5-HTTLPR and positive screening for mental disorders among children ...	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
Therefore, effects of 5-HTTLPR might be buffered by high social support with respect to the risk of ...	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
There was no positive correlation between the 5-HTTLPR polymorphism and presence of mental symptoms ...	DisGeNET	Detail
NA	DisGeNET	Detail
The differential susceptibility theory was examined by investigating the presence of interaction eff...	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
Functional genetic variation in the serotonin 5-HTTLPR modulates brain damage in frontotemporal deme...	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
We determined whether the 5-HTTLPR genotype predicted change in avoidance behavior in PDA following ...	DisGeNET	Detail
Therapygenetics: anterior cingulate cortex-amygdala coupling is associated with 5-HTTLPR and treatme...	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
Many reports suggests roles of N-terminal 17 amino acid domain of HTT (HTT-N17) towards subcellular ...	DisGeNET	Detail
NA	DisGeNET	Detail
The differential susceptibility theory was examined by investigating the presence of interaction eff...	DisGeNET	Detail
Functional genetic variation in the serotonin 5-HTTLPR modulates brain damage in frontotemporal deme...	DisGeNET	Detail
NA	DisGeNET	Detail
Huntington disease (HD), an autosomal dominant disorder involving HTT, is characterized by chorea, p...	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
Using data from the 1993 Pelotas Birth Cohort Study, and adopting a design as similar as possible to...	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
Association of Serotonin Transporter Promoter Polymorphism (5-HTTLPR) with Microscopic Colitis and U...	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
Huntington's disease (HD) is a dominant neurodegenerative disorder that is due to expansion of an un...	DisGeNET	Detail
NA	DisGeNET	Detail
The purpose of the present study was to examine whether a cumulative genetic score (CGS) containing ...	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
The results did not support the hypothesis that hypertension in pregnancy is a trait associated with...	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
NA	DisGeNET	Detail
The low activity variants of the 5-HTT-linked polymorphic region in the serotonin transporter gene a...	DisGeNET	Detail
The BDNF Val(66)Met x 5-HTTLPR x child adversity interaction and depressive symptoms: An attempt at ...	DisGeNET	Detail
Higher order interaction effects involving BDNF Val(66)Met, 5-HTTLPR and childhood adversity may con...	DisGeNET	Detail
These results suggest that both 5-HTTLPR and BDNF Val66Met moderate the relationship between life st...	DisGeNET	Detail
These results suggest that BDNF G196A as well as 5HTT-LPR polymorphisms confer risk for SB in BD, bu...	DisGeNET	Detail
5-HTTLPR and BDNF Val66Met polymorphisms and response to rTMS treatment in drug resistant depression...	DisGeNET	Detail
5-HTTLPR and BDNF Val66Met polymorphisms and response to rTMS treatment in drug resistant depression...	DisGeNET	Detail
Using clinical data and DNA samples from mouthwash gathered from an epidemiological study on the pre...	DisGeNET	Detail
Association of 5-HTTLPR serotonin transporter gene polymorphism and Val66Met brain-derived neurotrop...	DisGeNET	Detail
BDNF Val66Met is associated with introversion and interacts with 5-HTTLPR to influence neuroticism.	DisGeNET	Detail
Polymorphisms in BDNF (Val66Met) and 5-HTTLPR, morning cortisol and subsequent depression in at-risk...	DisGeNET	Detail
In the present study, we evaluated the impact of the BDNF Val66Met polymorphism on individual differ...	DisGeNET	Detail
This study aimed to investigate the association of alcohol use disorder (AUD) with four candidate ge...	DisGeNET	Detail
The 5-HTT linked polymorphic region (5-HTTLPR) and BDNF Val66Met polymorphisms were genotyped in 31 ...	DisGeNET	Detail
The serotonin transporter polymorphism (5-HTTLPR) and the brain-derived neurotrophic factor (BDNF) v...	DisGeNET	Detail
Functional variants of the MAOA-uVNTR, 5-HTTLPR, and BDNF Val66Met, either alone or in interaction w...	DisGeNET	Detail
Further, the two genotype combinations that differed the most in expression levels (BDNF Val66Met Va...	DisGeNET	Detail
Both 5-HTTLPR and BDNF Val66Met interacted with unfavourable environment in relation to depressive s...	DisGeNET	Detail
Using clinical data and DNA samples from mouthwash gathered from an epidemiological study on the pre...	DisGeNET	Detail
Genetic epistasis between the brain-derived neurotrophic factor Val66Met polymorphism and the 5-HTT ...	DisGeNET	Detail
Genetic epistasis between the brain-derived neurotrophic factor Val66Met polymorphism and the 5-HTT ...	DisGeNET	Detail
The low activity variants of the 5-HTT-linked polymorphic region in the serotonin transporter gene a...	DisGeNET	Detail
BDNF Val 66 Met and 5-HTTLPR genotype moderate the impact of early psychosocial adversity on plasma ...	DisGeNET	Detail
Further investigations in larger samples are needed to clarify the usefulness of 5-HTTLPR and BDNF V...	DisGeNET	Detail
Polymorphisms in BDNF (Val66Met) and 5-HTTLPR, morning cortisol and subsequent depression in at-risk...	DisGeNET	Detail
The low activity variants of the 5-HTT-linked polymorphic region in the serotonin transporter gene a...	DisGeNET	Detail
The present study is aimed to examine whether functional polymorphic variants, BDNF Val66Met, 5-HTTL...	DisGeNET	Detail
Associations between suicidal ideation and 5-HTTLPR, STin2 VNTR, 5-HTR2a 1438A/G, and 5-HTR2a 102T/C...	DisGeNET	Detail
Associations between suicidal ideation and 5-HTTLPR, STin2 VNTR, 5-HTR2a 1438A/G, and 5-HTR2a 102T/C...	DisGeNET	Detail
The aim of this study was to investigate the association of a serotonin transporter gene-linked poly...	DisGeNET	Detail
Association analysis of 5-HTTLPR variants, 5-HT2a receptor gene 102T/C polymorphism and migraine.	DisGeNET	Detail
The aim of this study was to investigate the association of a serotonin transporter gene-linked poly...	DisGeNET	Detail
The aim of this study was to investigate the role of serotonin in depression, searching for associat...	DisGeNET	Detail
No significant differences in the distribution of allele and genotype frequencies of the 5-HTTLPR (p...	DisGeNET	Detail
No significant differences in the distribution of allele and genotype frequencies of the 5-HTTLPR (p...	DisGeNET	Detail
The aim of this study was to investigate the association of a serotonin transporter gene-linked poly...	DisGeNET	Detail
As neuroimaging studies allude to dopaminergic and serotonergic dysfunction in GTS and serotonin as ...	DisGeNET	Detail
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This is the first study to test the association between HFs in both European-American and African-Am...	DisGeNET	Detail
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5-HTTLPR moderates naltrexone and psychosocial treatment responses in heavy drinking men who have se...	DisGeNET	Detail
Instead, based on current and previous findings, it is suggested that the S'/S' 5-HTTLPR genotype pr...	DisGeNET	Detail
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The SS genotype of the serotonin transporter gene (5-HTTLPR) was associated with high levels of impu...	DisGeNET	Detail
There was no positive correlation between the 5-HTTLPR polymorphism and presence of mental symptoms ...	DisGeNET	Detail
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Instead, based on current and previous findings, it is suggested that the S'/S' 5-HTTLPR genotype pr...	DisGeNET	Detail
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Two hundred healthy adults were exposed to a laboratory stressor (Trier Social Stress Test) and cort...	DisGeNET	Detail
Maternal behavior and infant 5-HTTLPR polymorphism have been linked to infants' social stress reacti...	DisGeNET	Detail
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We postulate that the HD-related cardiomyopathy is caused by altered central autonomic pathways alth...	DisGeNET	Detail
Interaction between serotonin transporter gene-linked polymorphic region (5-HTTLPR) and job-related ...	DisGeNET	Detail
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ACS patients with the 5-HTTLPR s allele are thus potentially susceptible to depressive disorder in t...	DisGeNET	Detail
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We first investigated tau pathology by looking for the presence of hyperphosphorylated tau aggregate...	DisGeNET	Detail
The serotonin transporter gene polymorphism 5-HTTLPR moderates the effects of stress on attention-de...	DisGeNET	Detail
The differential susceptibility theory was examined by investigating the presence of interaction eff...	DisGeNET	Detail
Brain Correlates of the Interaction Between 5-HTTLPR and Psychosocial Stress Mediating Attention Def...	DisGeNET	Detail
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Characterization of serotonin transporter gene (SLC6A4) polymorphisms and its association with drug ...	DisGeNET	Detail
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Although high neuroticism was significantly related to a higher frequency of stressful life events a...	DisGeNET	Detail
A functional polymorphism (5-HTTLPR) within the serotonin transporter gene (SERT) has been associate...	DisGeNET	Detail
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Serotonin transporter (5-HTTLPR) and norepinephrine transporter (NET) gene polymorphisms: susceptibi...	DisGeNET	Detail
The 5-HTT gene expression was almost silenced in chicken lymphoma DT40, myelomonocytic tumor HD11 an...	DisGeNET	Detail
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Therapygenetics: 5-HTTLPR genotype predicts the response to exposure therapy for agoraphobia.	DisGeNET	Detail
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Abnormal expression and genetic polymorphism of SLC6A3 and SLC6A4 genes may increase the risk of dev...	DisGeNET	Detail
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The 5-HTTLPR confers susceptibility to anorexia nervosa in Han Chinese: evidence from a case-control...	DisGeNET	Detail
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The reported interaction effects demonstrate that gender strongly modulates the relationship between...	DisGeNET	Detail
Strong evidence links the 5-HTTLPR genotype to the modulation of amygdala reactivity during fear con...	DisGeNET	Detail
Neither the treatment nor the reduced fMRI sample showed a direct effect of 5-HTTLPR on treatment re...	DisGeNET	Detail
To ascertain whether genetic variations in the serotonin transporter gene (5-HTTLPR 44-bp insertion/...	DisGeNET	Detail
Evaluation of the relationship between 5-HTT and MAO gene polymorphisms, mood and level of anxiety a...	DisGeNET	Detail
Selective serotonin reuptake inhibitors (SSRIs), such as citalopram, which selectively block seroton...	DisGeNET	Detail
Albeit 5-HTTLPR has only weak/moderate effects, the s allele is directly associated with anxiety and...	DisGeNET	Detail
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SLC6A4 markers modulate platelet 5-HT level and specific behaviors of autism: a study from an Indian...	DisGeNET	Detail
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5-HTTLPR modulated the relationship between early life stress and the core features of bipolar illne...	DisGeNET	Detail
A total of sixty-three genetic variants were selected on the basis of previous GWASs of MDD, SCZ, an...	DisGeNET	Detail
White matter microstructure in bipolar disorder is influenced by the serotonin transporter gene poly...	DisGeNET	Detail
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Overlapped Transcript Coordinates

Gene	Transcript ID	Exon Number	Chromosome	Start	Stop	Type	Amino Mutation	Transcript Position	Links

Overlapped Transcript

Gene	Transcript ID	Chromosome	Start	Stop	Links

Gene: -
dbSNP: rs386602118 dbSNP
Genome: hg19
Position: chr17:28,521,337-28,563,020
Variant Type: snv

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