Agitation

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Information
Disease name
Agitation
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT01329536 Completed The Occurrence of the ApoE4 Allele in Agitated In-Patients With Late-Onset Alzheimer's Disease December 2010 October 2011
NCT01517438 Completed N/A Effects of Serotonin Inhibitors on Patient-controlled Analgesia Related Nausea and Vomiting March 2011 December 2011
NCT01524367 Completed Phase 4 Effect of Single-dose Dexmedetomidine on Emergence Excitement in Adults With Nasotracheal Intubation After Orthognathic Surgery October 2011 January 2013
NCT01584440 Completed Phase 2 Efficacy, Safety and Tolerability Study of AVP-923 (Dextromethorphan/Quinidine) for Treatment of Symptoms of Agitation in Participants With Alzheimer's Disease August 13, 2012 July 30, 2014
NCT01715506 Completed N/A Continuing Education in Nursing Home Dementia Care August 2011 August 2015
NCT01747824 Completed Stress Biomarkers Among Patients Undergoing Treatment for Excited Delirium and Severe Pain in the Emergency Department December 2012 December 2015
NCT01848158 Completed N/A Acupuncture to Improve Comfort of Children on a Ventilator in the Intensive Care Unit March 2013 June 2016
NCT01856010 Completed Study of Electroconvulsive Therapy (ECT) Treatment for Agitation and Aggression in Dementia March 2011 October 2012
NCT01904760 Completed Phase 4 Dexmedetomidine to Prevent Agitation After Free Flap Surgery June 2013
NCT01976754 Completed N/A Safety Study of Dexmedetomidine in Septic Patients September 2013 July 2015
NCT02129348 Completed Phase 2 Treatment of Psychosis and Agitation in Alzheimer's Disease June 2014 January 2020
NCT02194036 Completed N/A Learning Oriented Physiotherapy - a New Approach August 2014 September 1, 2017
NCT02199262 Completed N/A Quality Improving Program on Agitation in the Surgical Intensive Care Unit February 2004 January 2005
NCT02203019 Completed Phase 4 Study of Sedative Medications in Patients With Severe Infection and Respiratory Failure August 2014 September 22, 2016
NCT02351882 Completed Phase 2/Phase 3 Safety and Efficacy of Nabilone in Alzheimer's Disease January 2015 March 2019
NCT02428283 Completed Phase 4 Scalp Nerve Block on Emergence Agitation May 2015 November 2016
NCT02525991 Completed Phase 4 Phase IV to Evaluate the Safety of Self-administered ADASUVE® in Agitated Patients Outside the Hospital Setting September 8, 2016 December 31, 2019
NCT02720705 Completed Phase 2/Phase 3 Transbucal Dexmedetomidine for Prevention of Sevoflurane Emergence Agitation in Pre-school Children May 2016 November 2018
NCT02848963 Completed Phase 4 Comparison of Ketamine-propofol Combinations July 2016 February 2017
NCT02863081 Completed Helping Older Persons Emerge Stronger July 2016 July 1, 2017
NCT03317067 Completed Phase 3 Effects of Dexmedetomidine on Delirium Duration of Non-intubated ICU Patients (4D Trial) December 21, 2017 February 23, 2023
NCT03554915 Completed Ketamine Versus Midazolam for Prehospital Agitation August 1, 2017 September 24, 2018
NCT03639558 Completed Phase 4 TREC-Lebanon: A Trial for Rapid Tranquilisation for Agitated Patients in the Emergency Setting August 28, 2018 July 7, 2019
NCT03773874 Completed Assessment of Analgesia, Sedation, Physical Restraints and Delirium in Spanish Intensive Care Units February 12, 2018 March 11, 2018
NCT04010305 Completed Phase 1 Sub-Lingual Dexmedetomidine in Agitation Associated With Schizophrenia May 22, 2019 July 31, 2019
NCT04266340 Completed N/A Different Premedication in Pediatric Patients December 13, 2020 December 1, 2021
NCT04268303 Completed Phase 3 Dexmedetomidine in the Treatment of Agitation Associated With Schizophrenia January 24, 2020 May 6, 2020
NCT04722614 Completed N/A Music and Essential Oil in Agitation April 11, 2021 July 20, 2022
NCT04908605 Completed Phase 4 Emergence Agitation After Nasal Surgery: a Randomized Controlled Comparison Between Melatonin and Mirtazapine June 15, 2021 March 31, 2022
NCT05165914 Completed N/A Midazolam Effect on Agitation Postnasal Surgery May 27, 2021 December 1, 2021
NCT05271552 Completed Phase 3 Dexmedetomidine in the Treatment of Agitation Associated With Dementia (TRANQUILITY II) April 27, 2022 April 21, 2023
NCT00351299 Completed Phase 2 Randomized Controlled Trial of Dexmedetomidine for the Treatment of Intensive Care Unit (ICU) Delirium January 2006 October 2012
NCT00417482 Completed Phase 4 Antipsychotic Discontinuation in Alzheimer's Disease August 2004 April 2011
NCT00457366 Completed Phase 4 A Comparison Study of the Efficacy of Quetiapine and Haloperidol in Agitated Adults in Emergency Room May 2006 May 2009
NCT00505804 Completed Phase 2 A Comparison of Dexmedetomidine and Haloperidol in Patients With Intensive Care Unit (ICU)-Associated Agitation and Delirium January 2005 November 2008
NCT00590499 Completed Agitation in Post Operative Neurosurgical Patients July 2012 March 2013
NCT00790075 Completed Phase 4 Liquid Risperidone in the Treatment of Acute Agitation in Psychiatrically Hospitalized Children January 2003 December 2004
NCT00797277 Completed Phase 3 Intramuscular (IM) Olanzapine Versus IM Haloperidol Plus Lorazepam for Acute Agitation in Schizophrenia July 2006 June 2009
NCT00857727 Completed Phase 3 Use of Dexmedetomidine to Reduce Emergence Delirium Incident in Children August 2009 December 2011
NCT00866645 Completed Phase 2/Phase 3 A Study To Evaluate The Efficacy And Safety Of Intramuscular Levosulpiride In Patients With Agitation Of Schizophrenia February 2009 July 2010
NCT00898807 Completed Phase 3 Citalopram for Agitation in Alzheimer's Disease July 2009 September 2013
NCT01021696 Completed Phase 2/Phase 3 Pain in Patients With Dementia and Behavioural Disturbances November 2009 October 2010
NCT01119638 Completed Phase 4 Escitalopram Treatment for BPSD in Alzheimer's Disease in Comparison to Risperidone April 2008 May 2010
NCT01217541 Completed N/A Collaboration Between Department of Old Age Psychiatry and Nursing Homes September 2010 March 2012
NCT01280890 Completed N/A Person- Centred Care Among Nursing Home Patients With Dementia February 2011 June 2012
NCT00009217 Completed Phase 4 Treatment of Behavioral Symptoms in Alzheimer's Disease January 1999 December 2004
NCT01400113 Completed Phase 4 Treating Acutely Agitated Patients With Asenapine Sublingual Tablets April 2012 December 2012
NCT01440114 Completed N/A The Effect of Intravenous Fentanyl Prior the End of Surgery on Emergence Agitation in Paediatric Patients After General Anesthesia March 2010 July 2011
NCT01501123 Completed N/A Pre-hospital Agitation and Sedation Trial: A Randomized Controlled Trial of Haloperidol Versus Midazolam for the Sedation of the Agitated Patient November 2011 December 2015
NCT06052254 Not yet recruiting Phase 2 Dexmedetomidine Transdermal Systems (DMTS) Treatment for Agitation Associated With Dementia of the Alzheimer's Type December 2023 December 2024
NCT05974527 Not yet recruiting Phase 4 Pilot Study 1: Efficacy and Safety of Sublingual Dexmedetomidine (BXCL501) for the Treatment of Agitation in the Emergency Department September 1, 2023 June 30, 2026
NCT05522647 Not yet recruiting Detection of Risk Behaviors: Pilot Observational Study With Bedridden and Agitated Patients. September 1, 2022 August 31, 2023
NCT06140342 Recruiting A Music-Based Mobile App for People Living With Alzheimer's Disease and Related Dementias (ADRD) August 1, 2023 January 1, 2025
NCT05644262 Recruiting Phase 2 Life's End Benefits of Cannabidiol and Tetrahydrocannabinol December 18, 2023 December 2025
NCT06037629 Recruiting Premature Enhanced Automated Capture of Comfort Knowledge February 1, 2023 January 2024
NCT05557409 Recruiting Phase 3 A Study to Assess the Efficacy and Safety of AXS-05 in Subjects With Alzheimer's Disease Agitation September 6, 2022 June 2025
NCT04516057 Recruiting Phase 3 Nabilone for Agitation Blinded Intervention Trial February 1, 2021 October 2025
NCT05397639 Recruiting Phase 3 Masupirdine for the Treatment of Agitation in Dementia of the Alzheimer's Type November 1, 2022 January 2025
NCT00315900 Terminated Phase 3 Depakote Extended Release (ER) Versus Seroquel for Agitated Behaviors in Nursing Home Care Unit Patients With Dementia May 1, 2006 February 28, 2008
NCT05665088 Terminated Phase 3 Dexmedetomidine in the Treatment of Agitation Associated With Dementia (TRANQUILITY III) December 14, 2022 September 11, 2023
NCT00833300 Terminated N/A Haloperidol vs Olanzapine for the Management of ICU Delirium June 2008 November 2011
NCT02846740 Terminated N/A Cranial Electric Stimulation to Modify Suicide Risk Factors in Psychiatric Inpatients. March 1, 2017 January 22, 2018
NCT03044249 Terminated Phase 2 A Study of MP-101 in Dementia-Related Psychosis and/or Agitation and Aggression May 4, 2017 January 30, 2020
NCT05276830 Terminated Phase 2 An Efficacy, and Safety Study Of BXCL501 For The Treatment Of Agitation Associated With Dementia February 8, 2022 April 1, 2022
NCT02164773 Unknown status Phase 4 Addition of Magnesium Sulfate to Caudal to Prevent Postoperative Emergence Agitation. October 2013 August 2014
NCT02590744 Unknown status N/A Effects of Preoperative Using of Eye Patches on Prevention of Emergence Agitation After Cataract Surgery October 2015 October 2017
NCT03398759 Unknown status N/A Butorphanol Mitigate Emergence Agitation in Patients Undergoing Functional Endoscopic Sinus Surgery February 1, 2018 December 31, 2020
NCT02216396 Unknown status A Naturalistic Two-year Cohort Study of Agitation and Quality of Life in Care Homes April 2014 December 2016
NCT04312893 Unknown status N/A The Effectiveness of Acupuncture for Delirium in Critically Ill Patients March 12, 2020 May 30, 2022
NCT04950738 Unknown status N/A The Effectiveness of Acupuncture for Complications in Critically Ill Patients August 1, 2021 September 30, 2022
NCT01374737 Unknown status Phase 4 ED50 of Dexmedetomidine to Prevent Emergence Agitation in Children June 2011 February 2012
NCT02104297 Unknown status Phase 4 Effect of Deksmedetomidine and Remifentanil in Extubation Agitation April 2014 June 2014
NCT05273671 Unknown status Phase 4 Nalbuphine Versus Dexmedetomidine for Prevention of Emergence Agitation in Pediatrics March 1, 2022 June 2, 2022
NCT02877108 Unknown status Naturalistic Adasuve Clinical Trial Study April 2016 April 2017
NCT04039269 Unknown status N/A Long Term Memory Preoperative Preparation Reduce Post Operative Behavioral Change December 2013 May 2020
NCT00786318 Withdrawn Phase 4 Ziprasidone vs Standard Therapy for Agitated Patients in the ED September 2008 July 2011
NCT02103881 Withdrawn Phase 4 Ketamine Versus Haloperidol for Severe Agitation Outside the Hospital April 2014 June 2014
NCT05313386 Withdrawn Phase 2 Study of BXCL501 In Agitation Associated With Delirium in ICU Patients February 23, 2021 February 21, 2022
NCT02118688 Withdrawn Phase 4 Efficacy and Safety of Risperidone and Trazodone Monotherapy and Combination Therapy in Critically Ill Patients With Delirium March 2011 March 2016
HPO Human Phenotype ID (Human Phenotype Ontology)
HP:0000713