Annotation Detail

Information
Associated Genes
SLC6A4
Associated Variants
SLC6A4 MUTATION
SLC6A4 MUTATION
Associated Disease
Depressive Symptoms
Source Database
DisGeNET
Description
The serotonin transporter polymorphism (5-HTTLPR) and the brain-derived neurotrophic factor (BDNF) val66met polymorphism have both been linked to depression symptoms and to depression diagnosis (MDD) in interaction with adversity; there have also been failures to find the effects.
Pubmed
21420735
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.021443907894344
Year of publication
2011
Drugs