Sleep Initiation and Maintenance Disorders

Search with Google Search with Bing
Information
Disease name
Sleep Initiation and Maintenance Disorders
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT04598672 Active, not recruiting N/A Cognitive Behavioral Therapy for Insomnia (CBTi) in Patients With Somatic Disease January 1, 2018 December 31, 2023
NCT03383354 Active, not recruiting The Link Between Clinical and Physiological Sleep Data and Health-related Outcomes January 1, 2004 June 2025
NCT00690196 Active, not recruiting N/A Tai Chi Effects on Chronic Insomnia in Breast Cancer Survivors: Immune Mechanisms March 2008 July 31, 2025
NCT00079664 Completed Phase 1 Comparing Tai Chi Training to a Low-Stress Physical Activity to Enhance Sleep in Older Adults September 2001 July 2003
NCT00097604 Completed Phase 2 Effects of Valerian on Sleep in Healthy Older Adults September 2004 April 2008
NCT00149747 Completed Phase 2/Phase 3 The Effectiveness of Regular Exercise on Improving Sleep in Older Adults August 1999 September 2003
NCT00167375 Completed Testing the Nocturnal Sleep Latency Profile in Primary Insomnia January 2005 June 2007
NCT00183378 Completed N/A Using Behavioral Programs to Treat Sleep Problems in Individuals With Alzheimer's Disease September 2005 March 2011
NCT00207285 Completed N/A Sleep Disorders Management, Health and Safety in Police May 2005 September 2010
NCT00227942 Completed Phase 4 Estrogen for Treating Depression in Menopausal Women With Hot Flashes and Insomnia August 2003 November 2007
NCT00230737 Completed Phase 2 Effects of Melatonin on Insomnia Symptoms in Older Adults October 2004 May 2008
NCT00246051 Completed N/A Comprehensive Police Fatigue Management Program November 2005 December 2010
NCT00247624 Completed Phase 4 Improving Sleep and Psychological Functioning in People With Depression and Insomnia October 2005 December 2008
NCT00253903 Completed Phase 3 Efficacy and Safety of Eplivanserin Treatment for Sleep Maintenance Insomnia Followed by Optional Extension up to 1 Year November 2005 September 2008
NCT00253968 Completed Phase 3 Efficacy and Safety of Eplivanserin Treatment for Sleep Maintenance Insomnia November 2005 January 2008
NCT00259311 Completed Phase 2 Efficacy Study of LY2422347 to Treat Insomnia November 2005 November 2006
NCT00280423 Completed Phase 2 Effects Of GW679769 On Sleep Onset And Maintenance And Next Day Functioning In Subjects With Primary Insomnia January 2006 February 2007
NCT00280436 Completed Phase 2 Effects Of GW679769 On Sleep Onset And Maintenance,And Next Day Functioning In The Elderly And Non-elderly With Primary Insomnia January 2006 March 2007
NCT00283946 Completed Phase 3 A Double-blind, Group-comparison Study Using Zolpidem (Myslee) as a Comparative Drug in Patients With Insomnia February 2006 November 2007
NCT00292734 Completed Phase 4 STILDEP: Zolpidem in Depressive and Dysthimic Patients January 2005 June 2006
NCT00308503 Completed Phase 3 Efficacy and Safety of Eplivanserin 5mg/Day on Sleep Maintenance Insomnia February 2006 August 2007
NCT00321451 Completed Phase 2/Phase 3 Cognitive Behavioral Insomnia Therapy for Individuals With Fibromyalgia May 2006 February 2011
NCT00328250 Completed Phase 1/Phase 2 Effectiveness of Internet Cognitive Behavioral Therapy Intervention for Treating Insomnia October 2006 July 2009
NCT00347295 Completed Phase 3 Randomised, Double-blind Study to Investigate the Safety and Efficacy of Brotizolam in Insomnia Outpatients. June 2006 January 2007
NCT00354809 Completed Phase 2 Evaluation of A Morning Dosing Of A New Medicine And Its Effects On Sleep At Bedtime In Subjects With Primary Insomnia May 2006 July 2007
NCT00365261 Completed Phase 4 Effect of Eszopiclone on Sleep Disturbance and Pain in Cancer September 2006 December 2009
NCT00374777 Completed Phase 3 A Double-blind, Group-comparison P-III Study With Zolpidem MR Using Placebo and Nitrazepam in Insomnia Patients August 2006 June 2008
NCT00380003 Completed Phase 2 Efficacy Study of EVT 201 to Treat Insomnia September 2006 April 2007
NCT00381199 Completed N/A Nabilone Versus Amitriptyline in Improving Quality of Sleep in Patients With Fibromyalgia April 2006 March 2007
NCT00383643 Completed Phase 2 Xyrem(Sodium Oxybate) and Ambien(Zolpidem Tartrate) in the Treatment of Chronic Insomnia. May 2006 December 2009
NCT00401284 Completed Phase 2 Efficacy Study of EVT 201 in the Treatment of Elderly Patients With Daytime Sleepiness November 2006 July 2007
NCT00425243 Completed Phase 3 Efficacy and Safety of Zolpidem-MR Administered Over a Long Term Period as Needed for Insomnia (ZOLONG) August 2004 January 2006
NCT00426816 Completed Phase 2 To Evaluate The Effects Of SB-649868 (10, 30 Mg And 60 Mg) On Subjects With Primary Insomnia December 2006 May 2007
NCT00434876 Completed Phase 3 The Effects of Quetiapine (Seroquel XR) on Sleep During Alcohol Abstinence August 2007 December 2009
NCT00005753 Completed Pharmacological and Behavioral Treatment of Insomnia June 1997 May 2002
NCT00440323 Completed Phase 1 Disturbed Sleep Model Study. January 5, 2007 July 3, 2007
NCT00042146 Completed Phase 4 Behavioral and Pharmacological Treatment for Insomnia December 2001
NCT00044629 Completed Phase 2 Combined Behavioral/Pharmacological Therapy for Insomnia September 2001 August 2006
NCT01135342 Completed N/A Adding Sleep Intervention to Traditional Diet and Exercise Approach to Weight Loss July 2009 March 2010
NCT01154023 Completed N/A Behavioral Intervention for Insomnia in Older Adults September 2000 August 2004
NCT01162018 Completed N/A Acupuncture for Sleep Disruption in Cancer Survivors February 2011 August 2012
NCT01176123 Completed N/A Cognitive Behavioral Therapy for Trauma-Related Insomnia in Veterans February 3, 2011 September 27, 2011
NCT01181232 Completed Phase 4 A Study to Compare Efficacy and Safety of Zolpidem Modified Release Formulation Versus Zolpidem in Insomnia Patients October 2009 April 2011
NCT01438697 Completed Phase 3 An Interactive Internet Intervention for Adults With Insomnia October 2011 October 2014
NCT01450228 Completed Phase 3 Efficacy and Safety of KI1001 in ≥ 55 Years Old Insomnia Patients March 2011 March 2012
NCT01686438 Completed N/A Telemedicine Management of Chronic Insomnia April 1, 2013 November 30, 2016
NCT01784614 Completed Phase 1 A Study of LY2624803 in Japanese Participants With Transient Insomnia September 2009 March 2010
NCT01824472 Completed N/A Understanding the Sleep Apnea/Insomnia Interaction March 2013 March 2017
NCT01846585 Completed N/A Treatment for Insomnia During Pregnancy April 2013 March 2018
NCT02087722 Completed Phase 3 Efficacy and Safety of KI1001 in the Treatment of ≥ 55 Years Old Insomnia Patients August 2013 January 2014
NCT02183714 Completed Phase 3 The Ability of Songha Night ® to Improve Sleep in Patients With Mild to Moderate Sleep Disturbances May 1998
NCT02224014 Completed Lendormin D® Tablet (Drug Use Result Survey) June 2005
NCT02559739 Completed Sleep Deficiency and Stroke Outcome July 2015 March 2022
NCT02660385 Completed N/A Insomnia Self-Management in Heart Failure March 7, 2016 November 30, 2021
NCT02709369 Completed N/A HIRREM Developmental Study August 23, 2011 October 25, 2018
NCT02750306 Completed Phase 3 Safety and Efficacy of Suvorexant (MK-4305) for the Treatment of Insomnia in Participants With Alzheimer's Disease (MK-4305-061) May 23, 2016 September 30, 2018
NCT02984670 Completed N/A Cognitive Behavior Therapy for Insomnia: Analysis of Components, Mediators and Moderators August 2016 November 2017
NCT03177967 Completed N/A "Get up" - The Sleep Study in Oppegard April 24, 2017 December 1, 2017
NCT03213132 Completed N/A Sleep Healthy Using The Internet for Older Adult Sufferers of Insomnia and Sleeplessness February 13, 2018 November 1, 2020
NCT03320083 Completed N/A Behavioral Insomnia of Childhood: Impact of Parent Education February 1, 2016 October 30, 2016
NCT03636880 Completed N/A Heart Failure Insomnia Treatment Study February 24, 2017 August 29, 2023
NCT03673397 Completed N/A The Acute Effect of Aerobic Exercise on Sleep in Patients With Depression September 24, 2018 January 6, 2020
NCT03677726 Completed N/A Improving Sleep Continuity Through Mindfulness Training for Better Cognitive Ageing. August 1, 2018 June 10, 2021
NCT03687086 Completed N/A Sleep Without Insomnia or The Use of Chronic Hypnotics December 11, 2018 November 27, 2023
NCT03763071 Completed Sleep Disturbances in the 2nd and 3rd Trimester December 7, 2018 April 29, 2020
NCT03852966 Completed N/A Better Sleep in Psychiatric Care - ADHD Pilot Study September 1, 2015 October 31, 2016
NCT03934658 Completed N/A Remote Study of NightWare for PTSD With Nightmares May 21, 2019 December 15, 2021
NCT04224285 Completed N/A Operational Trial of Dayzz App August 12, 2020 September 30, 2021
NCT04549168 Completed Phase 3 A Study of Lemborexant in Chinese Participants With Insomnia Disorder November 6, 2020 March 17, 2023
NCT04560595 Completed N/A Remote Guided Caffeine Reduction September 10, 2020 October 1, 2023
NCT04573556 Completed A Study to Evaluate the Safety of DAYVIGO (Lemborexant) Tablets in Participants With Insomnia. October 17, 2020 March 17, 2022
NCT04598425 Completed N/A Cognitive Behavioral Therapy for Insomnia (CBTi) in Patients With Mental Illness August 1, 2018 August 31, 2021
NCT04661306 Completed N/A The Better Sleep for Supporters With Insomnia Study September 30, 2020 January 31, 2022
NCT04838067 Completed N/A Validation of Therapeutic Effects of Cefaly on Insomnia July 26, 2018 July 14, 2020
NCT04986904 Completed N/A Optimizing Efficiency and Impact of Digital Health Interventions for Caregivers January 11, 2022 March 19, 2023
NCT05065242 Completed N/A Smartphone-delivered CBT-I August 20, 2021 November 20, 2022
NCT05128812 Completed N/A Study of the Effects of Plx on Bioparametric Measurements. May 1, 2021 December 1, 2022
NCT05332717 Completed N/A TKA Melatonin and Sleep Quality January 10, 2022 April 30, 2022
NCT05611099 Completed N/A Robustness and Usability of the Dreem 3 System for at Home Sleep Monitoring in an Insomnia Population. August 15, 2022 November 5, 2022
NCT06306495 Completed Insomnia, Physical Activity Level and Stress Level March 27, 2022 January 29, 2024
NCT00464243 Completed Phase 3 Efficacy and Safety of Volinanserin on Sleep Maintenance Insomnia - Polysomnographic Study April 2007 January 2008
NCT00495274 Completed Phase 1 Bioequivalence and Food Effect Study in Healthy Volunteers July 2, 2007 September 26, 2007
NCT00495729 Completed Phase 1 15-Day Repeated-Dose Study With SB-649868 And Its Interaction With CYP3A4 Isoenzyme In Healthy Male Subjects. April 18, 2007 August 4, 2007
NCT00495885 Completed Phase 3 Efficacy and Safety of M100907 on Sleep Maintenance Insomnia With a Sub-study in Stable Type II Diabetes Mellitus June 2007 October 2008
NCT00520663 Completed Phase 1 Radiolabel Study In Healthy Volunteers For Insomnia-Targeting Drug June 8, 2007 August 10, 2007
NCT00561821 Completed Phase 3 Efficacy and Safety Study of Org 50081 (Esmirtazapine) in Elderly Participants (P05709) November 20, 2007 December 21, 2009
NCT00592449 Completed N/A Sleep in Osteoarthritis Project April 2008 January 2014
NCT00594087 Completed N/A Eszopiclone for Improving Sleep in Multiple Sclerosis (MS) December 2006 June 2008
NCT00606697 Completed Phase 2 A Study With GW597599 And GR205171: Potential New Drugs For The Treatment Of Primary Insomnia December 19, 2007 May 7, 2008
NCT00630175 Completed Phase 3 Evaluation of the Hypnotic Properties of Zolpidem-MR 12.5 mg and Zolpidem 10 mg Marketed Product Compared to Placebo in Patients With Primary Insomnia September 2003 February 2004
NCT00631657 Completed Phase 3 A 6-Month Efficacy and Safety Study of Org 50081 in Adult Patients With Chronic Primary Insomnia (21106/P05701/MK-8265-002) March 4, 2008 November 19, 2009
NCT00650871 Completed Phase 2 A Study to Evaluate the Effects of GW679769 on Sleep and Cognitive Function in Subjects With Primary Insomnia July 30, 2004 August 30, 2005
NCT00653562 Completed Phase 4 Zolpidem (Myslee) Post Marketing Study in Adolescent Patients With Insomnia - Evaluation With Polysomnography November 2006 March 2010
NCT00661843 Completed N/A A Study of Yoga for Treating Geriatric Insomnia May 2008 February 2009
NCT00671086 Completed Phase 3 Efficacy of Ramelteon in Subjects With Chronic Insomnia February 2003 September 2004
NCT00679900 Completed Phase 3 Comparison of Eplivanserin and Lormetazepam in the Treatment of Insomnia Characterized by Sleep Maintenance Difficulties April 2008 March 2009
NCT00699608 Completed Phase 3 An Evaluation of Potential Next-day Residual Effects of Eszopiclone in Healthy Volunteers. July 2008 October 2008
NCT00755495 Completed Phase 2 Safety and Efficacy of Ramelteon and Doxepin in Subjects With Chronic Insomnia July 2006 March 2007
NCT00755508 Completed Phase 2 Efficacy and Safety of Ramelteon Combined With Gabapentin in Treating Patients With Insomnia November 2005 September 2006
NCT00756002 Completed Phase 3 Safety and Efficacy Study of Ramelteon in Subjects With Chronic Insomnia August 2007 March 2008
NCT00767624 Completed Phase 2/Phase 3 TRIAD - Treatment of Insomnia and Depression December 2008 June 2015
NCT00798395 Completed Phase 1 A Study to Assess the Effect of Single and Multiple Doses Org 50081 and a Single Dose of Zopiclone on Next-day Driving Ability and Psychomotor Performance in Healthy Volunteers. (P05794) (COMPLETED) October 2007 September 2008
NCT00868517 Completed N/A Examining the Effect of Acupuncture on Sleep Difficulties Related to Post Traumatic Stress Disorder October 2009 December 2011
NCT00913614 Completed Phase 1 Single Dose Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Evaluation of Eplivanserin in Children With Insomnia June 2009 December 2009
NCT00946530 Completed N/A Light Treatment for Sleep/Wake Disturbances in Alzheimer's Disease September 2004 December 2010
NCT00956319 Completed Phase 4 A Study to Evaluate Efficacy and Safety of Zolpidem Modified Release Formulation in Insomnia Patients May 2009 November 2010
NCT00999219 Completed Phase 3 A Study of FK199B to Compare Efficacy With Zolpidem by Polysomnography in Patients With Insomnia March 2006 July 2007
NCT01050465 Completed N/A MedlinePlus Health Prescriptions: Developing a Pragmatic Approach for Clinic Use May 2009 December 2010
NCT05665764 Enrolling by invitation The Feasibility of Home-Based Measurement of Circadian Timing for Veterans With TBI and Insomnia July 1, 2023 June 30, 2025
NCT05530863 Enrolling by invitation N/A Behavioral Relaxation Approaches for Insomnia in Pregnant Patients April 1, 2022 September 27, 2026
NCT05753943 No longer available CLINICAL TRIAL PHASE II, MULTICENTRIC, NATIONAL, DOUBLE-BLIND, PARALLEL, RANDOMIZED, AND PLACEBO-CONTROLLED FOR EVALUATION OF THE IMPROVEMENT OF SLEEP QUALITY IN PARTICIPANTS OF RESEARCH WITH INSOMNIA DISORDER
NCT04980703 Not yet recruiting N/A Grain Moxibustion Treatment on Insomnia: a Randomized Controlled Trial July 1, 2024 July 31, 2025
NCT05226585 Recruiting N/A Mechanisms of Change in Cognitive Behavioral Therapy for Insomnia (CBTi) October 21, 2021 December 31, 2024
NCT05594589 Recruiting Phase 2 A Study to Assess the Pharmacodynamics of Lemborexant in Korean Participants With Insomnia Disorder November 30, 2022 May 28, 2024
NCT03843645 Recruiting N/A General Versus Regional Anesthesia and Postoperative Sleep Quality February 10, 2019 December 31, 2023
NCT06363656 Recruiting Assessment of Smartwatch SAMSUNG to Monitor Sleep Quality: an Observational Prospective Study - SleepEx2 Protocol February 15, 2024 July 30, 2024
NCT05778812 Recruiting N/A Online Insomnia Treatment Program August 11, 2023 April 2024
NCT04092894 Recruiting Phase 4 Suvorexant and Sleep/Delirium in ICU Patients February 28, 2020 July 1, 2025
NCT05965609 Recruiting N/A Optimizing Sleep Health in Nurses December 8, 2023 August 11, 2025
NCT05000528 Recruiting N/A Evaluation of the Effectiveness of Patient Therapeutic Education on Chronic Insomnia September 30, 2022 September 29, 2025
NCT05565833 Recruiting Phase 2 Sleep Healthy Using the Internet Mitigating Insomnia to Address Neurocognitive Difficulties (SHUTi MIND) February 27, 2023 January 2028
NCT04986007 Recruiting N/A Addressing Nocturnal Sleep/Wake Effects on Risk of Suicide in Older Adults September 1, 2021 September 1, 2025
NCT06067139 Recruiting N/A Sleep for Health Study on the Effects of Cognitive Behavioral Therapy for Insomnia on Diabetes Risk August 1, 2023 March 2027
NCT03642028 Recruiting Phase 4 Suvorexant: A Dual Orexin Receptor Antagonist for Treating Sleep Disturbance in Posttraumatic Stress August 30, 2019 December 31, 2024
NCT00427323 Suspended N/A Light Exposure to Treat Sleep Disruption in Older People June 2006 September 2007
NCT00464061 Terminated Phase 3 Efficacy an Safety of Volinanserin on Sleep Maintenance Insomnia With a Sub-study on Stable Type II Diabetes Mellitus April 2007 March 2009
NCT01921296 Terminated Phase 2 Pilot Study of Cyclobenzaprine for Treatment of Sleep Disturbance in Aromatase Inhibitor-treated Breast Cancer Patients August 2013 April 2015
NCT01928173 Terminated N/A Self-Help Video for Insomnia in College Students February 2013 November 2016
NCT02102230 Terminated N/A CBT-I for Cannabis Use November 3, 2014 March 24, 2017
NCT02183233 Terminated Phase 3 Efficacy and Safety of Eschscholtzia Californica in Treating Primary Insomnia January 1998
NCT00626210 Terminated Phase 4 Modafinil Treatment for Sleep/Wake Disturbances in Older Adults February 2008 October 2012
NCT00750919 Terminated Phase 3 Twenty-six Week Extension Trial of Org 50081 (Esmirtazapine) in Outpatients With Chronic Primary Insomnia (176003/P05721/MK-8265-007) October 7, 2008 March 10, 2010
NCT02758990 Terminated N/A Interventional Testing of Gene-environment Interactions Via the Verifomics Mobile Application March 2016 November 23, 2016
NCT00183430 Terminated N/A Prazosin for Treating Noncombat Trauma Post-Traumatic Stress Disorder October 2003 December 2010
NCT00788515 Terminated Phase 3 Comparison of Volinanserin and Lormetazepam in the Treatment of Insomnia Characterized by Sleep Maintenance Difficulties November 2008 January 2009
NCT03662581 Terminated N/A Evaluating a Primary-Care Group-based Mindfulness Program November 30, 2018 December 30, 2020
NCT03276585 Unknown status Night in Japan Home Sleep Monitoring Study September 6, 2017 August 31, 2019
NCT04550507 Unknown status N/A Mind-Body Interventions to Mitigate Effects of Media Use on Sleep in Early Adolescents October 22, 2020 October 2021
NCT02594670 Unknown status N/A Acupuncture for Insomnia: a Randomized Controlled Trial October 2015 August 2017
NCT05257317 Unknown status N/A Efficacy of Cranial Manual Therapy in the Treatment of Chronic Insomnia Disorder February 2022 September 2023
NCT00445133 Unknown status Phase 4 Study on Magnetic Field Therapy to Improve Quality of Sleep and Reduction of Chronic Spine Pain February 2007 December 2007
NCT02402959 Unknown status Individualized Treatment With Traditional Chinese Medicine for the Patients With Insomnia Disorder: a Cohort Study March 2015 February 2016
NCT02255721 Unknown status N/A Sleep Health in Preschoolers: a Randomized Controlled Trial November 2013 December 2020
NCT04417153 Unknown status Who Benefits More? Optimising Mindfulness Based Interventions for Improved Psychological Outcomes September 20, 2019 June 30, 2022
NCT03828656 Unknown status N/A NightWare Open Enrollment Study February 1, 2019 February 1, 2022
NCT04405427 Unknown status N/A A Comparison of the Therapeutic Effect Between Head-point Acupuncture and Conventional Body Acupuncture on Insomnia August 7, 2020 August 31, 2021
NCT04255901 Unknown status Efficacy of Head-point Acupuncture on Insomnia August 1, 2020 June 30, 2021
NCT04228146 Unknown status N/A Self-help Smartphone-delivered Cognitive Behavioral Therapy for Insomnia in People With Depression and Insomnia March 19, 2019 June 2021
NCT03997058 Unknown status Phase 4 Observation on the Effect of Auricular Acupoint Pressing on Insomnia and Adverse Events in MHD March 1, 2019 January 1, 2021
NCT02521324 Withdrawn N/A Effect of Device Guided Breathing on Sleeplessness (2BRT01) May 2018 January 2020
MeSH unique ID (MeSH (Medical Subject Headings))
D007319