Tauopathies

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Information
Disease name
Tauopathies
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT05522387 Active, not recruiting Phase 2 An Open-Label Extension of XPro1595 in Patients With Alzheimer's Disease February 21, 2023 September 30, 2024
NCT05344989 Active, not recruiting Phase 1 A First-in-Human Study to Assess Single Doses of APNmAb005 in Healthy Participants May 6, 2022 July 2024
NCT02676843 Completed Phase 2 Tau PET Imaging With 18F-AV-1451 in Subjects With MAPT Mutations April 2016 November 25, 2018
NCT02860338 Completed COMPARATIVE EFFECTIVENESS OF MCI and DEMENTIA TREATMENTS IN A COMMUNITY-BASED DEMENTIA PRACTICE January 2009 December 2015
NCT03538522 Completed Phase 2 A Double-Blind, Placebo-Controlled Safety and Efficacy Study of NA-831 September 15, 2018 October 30, 2019
NCT03938870 Completed CNS Tau Kinetics in Healthy Aging and Alzheimer's Disease August 18, 2015 July 6, 2023
NCT04445831 Completed Phase 1/Phase 2 A Study to Evaluate the Safety, Tolerability and Immunogenicity of Tau Targeted Vaccines in Participants With Early Alzheimer's Disease July 31, 2019 September 5, 2023
NCT05080777 Completed N/A Pilot Pragmatic Clinical Trial to Embed Tele-Savvy Into Health Care Systems September 28, 2021 June 5, 2023
NCT05202223 Completed N/A Harmony at Home: A Pilot Telehealth Program for Rural ADRD Caregivers January 15, 2022 December 8, 2022
NCT02103894 Completed Phase 1 Evaluation of [18F]MNI-777 PET as a Marker of Tau Pathology in Subjects With Tauopathies Compared to Healthy Subjects February 2014 September 2016
NCT05527288 Completed N/A A Bridging Study on Efficacy and Safety of [18F]Florbetaben PET for Diagnosis of Alzheimer Disease Subjects in Chinese Population January 28, 2021 September 12, 2021
NCT02294851 Completed Phase 1 A Randomized, Double-Blind, Placebo-Controlled, Single Ascending Dose Study of Intravenously Administered BMS-986168 in Healthy Subjects December 31, 2014 April 30, 2016
NCT06303921 Recruiting Early Phase 1 Study of Biodistribution, Metabolism, Excretion and Brain Uptake11C-M503 February 16, 2024 February 2029
NCT05318976 Recruiting Phase 2 A Study of XPro1595 in Patients With Early Alzheimer's Disease With Biomarkers of Inflammation February 28, 2022 December 31, 2024
NCT05427448 Recruiting N/A Validation of Blood Biomarkers for Alzheimer's Disease November 24, 2022 December 31, 2024
NCT05508789 Recruiting Phase 3 A Study of Donanemab (LY3002813) in Participants With Early Symptomatic Alzheimer's Disease (TRAILBLAZER-ALZ 5) October 10, 2022 April 30, 2027
NCT06032026 Recruiting Early Phase 1 Study of Biodistribution, Metabolism, Excretion and Brain Uptake of 11C-HY-2-15 August 2, 2023 July 31, 2028
NCT06083467 Recruiting Early Phase 1 CW2IP2: Imaging and Diagnostic Assessments July 20, 2023 July 31, 2028
NCT01696591 Unknown status The Long-Term Safety and Efficacy Follow-Up Study of Subjects Who Completed the Phase I Clinical Trial of Neurostem®-AD March 2012 September 2013
NCT05321498 Withdrawn Phase 2 Study to Assess the Efficacy of XPro1595 in Patients With Mild Cognitive Impairment With Biomarkers of Inflammation June 2023 October 26, 2023
MeSH unique ID (MeSH (Medical Subject Headings))
D024801