Annotation Detail

Information
Associated Genes
SLC6A4
Associated Variants
SLC6A4 MUTATION
SLC6A4 MUTATION
Associated Disease
Anxiety Disorders
Source Database
DisGeNET
Description
Albeit 5-HTTLPR has only weak/moderate effects, the s allele is directly associated with anxiety and modulates development of depression in homogeneous subgroups.
Pubmed
25747798
Section of the abstract supporting the evidence
CONCLUSIONS
Number of the section of the abstract supporting the evidence
5
Number of the sentence supporting the evidence
13
Original source reporting the Gene Disease association
BeFree,CTD_human,GAD,RGD
DisGENET score for the Gene Disease association
0.264310655727945
Drugs