heroin dependence

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Information
Disease name
heroin dependence
Disease ID
DOID:9976
Description
"An opiate dependence that involves the continued use of heroin despite problems related to use of the substance." [url:http\://en.wikipedia.org/wiki/Opioid_dependence]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT04495673 Completed N/A Combining Neuro-Imaging and Non-Invasive Brain Stimulation for Clinical Intervention in Opioid Use Disorder January 11, 2021 February 22, 2022
NCT00000211 Completed Phase 2 Treatment Efficacy for Drug Abuse and AIDS Prevention - 2 September 1989 February 1996
NCT00000273 Completed Phase 2 A Laboratory Model for Heroin Abuse Medications - 8 August 1995 November 2005
NCT00000302 Completed Phase 3 Study Comparing Liquid and Tablet Buprenorphine Formulations - 5
NCT00608504 Completed Effects of Environmental Factors on Opiate Drug Choice in Opioid Dependent Individuals. July 2007 April 2009
NCT00684554 Completed Phase 2/Phase 3 Buprenorphine Maintenance Treatment of Opioid Dependence in Primary Care: A Randomized Clinical Trial December 2007 April 2010
NCT00684840 Completed Effects of Stress and Other Factors on Opiate Drug Choice. March 2008 December 2011
NCT00698737 Completed Treatment Study: Reducing Cocaine/Heroin Abuse With SR-Amphetamine and Buprenorphine (ARC) April 2008 November 2012
NCT00759005 Completed N/A Effect of Stress on Heroin-Related Memory Retrieval March 2007 September 2008
NCT00894452 Completed Variance of Oral Methadone Dosage: Description of Implicated Factors December 2008 May 2013
NCT01315184 Completed Phase 2 Study of Computer-Based Treatment for Drug Dependence July 2010 July 2012
NCT01447212 Completed Phase 3 Study to Assess Longer-term Opioid Medication Effectiveness (SALOME) December 2011 February 2016
NCT01471145 Completed Phase 4 Depot Naltrexone Mechanism of Action in Heroin Dependent Patients Using fMRI and SPECT January 2013 October 2014
NCT01536925 Completed Studies of Opioid Seeking Behavior: Yohimbine and Hydrocortisone Effects December 2011 April 2017
NCT01668706 Completed Pharmacogenomics Study of Sleep Disturbance and Neurocognitive Impairments in the Opioid Addicts March 2009 December 2013
NCT01723527 Completed Phase 1 Diversion to Treatment for Injection Drug Users Arrested for Possession of Heroin December 2012 August 2014
NCT01760473 Completed Phase 3 Reinforcing Effects of Intranasal (IN) Buprenorphine Versus Buprenorphine/Naloxone May 2009 December 2014
NCT01999946 Completed Phase 4 Extended-Release Naltrexone Opioid Treatment at Jail Re-Entry June 27, 2014 December 24, 2020
NCT02324725 Completed Phase 4 Biomarkers of Injectable Extended Release Naltrexone Treatment October 2011 December 2021
NCT02774954 Completed N/A Change the Cycle: An RCT to Prevent Injection Initiation June 2016 November 2019
NCT03015246 Completed Phase 1/Phase 2 Effects of Buprenorphine/Naloxone Dose on Experimental Stress Reactivity and Opioid Abstinence December 2016 August 2020
NCT03071315 Completed Economic Evaluation Comparing CCT With MMT in Hai Phong City, Vietnam January 20, 2013 January 30, 2015
NCT04133974 Completed N/A Methadone Induced Memory Retrieval-extinction Procedure in Heroin Addicts November 20, 2015 April 20, 2019
NCT00000210 Completed Phase 2 Treatment Efficacy for Drug Abuse and AIDS Prevention - 1 September 1989 February 1996
NCT00015171 Completed Phase 3 Buprenorphine and Naloxone for the Treatment of Opiate Dependence - 1 April 1996 June 1997
NCT00015288 Completed Phase 1 Buprenorphine and Naloxone Combination Study - 10 November 1996
NCT00023283 Completed Phase 2 Counseling Conditions for Buprenorphine in a Primary Care Clinic - 1 August 2000 February 2004
NCT00032955 Completed Phase 3 Buprenorphine/Naloxone Versus Clonidine for Inpatient Opiate Detoxification - 1 February 2001 August 2002
NCT00032968 Completed Phase 3 Buprenorphine/Naloxone Versus Clonidine for Outpatient Opiate Detoxification - 1 January 2001 August 2002
NCT00135759 Completed Phase 2 Addition of Naltrexone to Methadone Taper April 2005 July 2006
NCT00142948 Completed Phase 2 Naltrexone and Adrenergic Agents to Reduce Heroin Use in Heroin Addicts February 2006 May 2011
NCT00149669 Completed N/A Employment-based Reinforcement of Naltrexone Ingestion and Abstinence December 2005 December 2010
NCT00158288 Completed Phase 2 The Efficacy of Methadyl Acetate (LAAM) and Contingency Management Procedures for Treating Dual Opioid and Cocaine Abuse - 1 March 1997 August 2001
NCT00218127 Completed Phase 2 Treatment of Opioid/Heroin Dependence: Comparison of Three Medication Dosing Regimens November 2001 July 2005
NCT00218309 Completed Effects of Pre-Session Supplemental Hydromorphone on Drug Seeking Behavior in Opioid Dependent Individuals September 2003 July 2005
NCT00218361 Completed Effects of Post-Session Supplemental Hydromorphone on Drug Seeking Behavior in Opioid Dependent Individuals August 2005
NCT00218426 Completed Phase 2/Phase 3 Addiction Treatment in Russia: Oral vs. Naltrexone Implant July 2006 November 4, 2010
NCT00218530 Completed Phase 1 Effectiveness of Naltrexone and Lofexidine in Treating Detoxified Heroin Addicts - 1 March 2003 September 2004
NCT00218634 Completed N/A Skills Based Counseling for Adherence and Depression in HIV+ Methadone Patients - 1 February 2005 July 2009
NCT00238914 Completed Phase 2 Opiate Dependence: Combined Naltrexone/Behavior Therapy - 1 August 1999 July 2002
NCT00249457 Completed N/A Employment-based Reinforcement to Motivate Drug Abstinence in the Treatment of Drug Addiction. - 2 October 1996 January 2006
NCT00249470 Completed N/A The Therapeutic Workplace Initiation Study April 2003 October 2004
NCT00249574 Completed N/A Bridging Active Heroin Users to Hepatitis C Treatment Using Buprenorphine - 1 June 2003 June 2006
NCT00279110 Completed Phase 2/Phase 3 Directly Administered HIV Therapy in Methadone Clinics April 2006 May 2011
NCT00310934 Completed Phase 4 A Stepwise Strategy Utilizing Buprenorphine and Methadone August 2005 March 2006
NCT00326235 Completed Phase 4 Effects of Buspirone in Opiate Withdrawal January 2002 July 2004
NCT00429767 Completed Sustained Release d-Amphetamine & Buprenorphine on Drug Seeking Behavior in Opioid & Cocaine Dependent Individuals January 2007 January 2010
NCT00471042 Completed Study of Buprenorphine Maintenance Treatment for Opioid Dependence in Primary Care June 2006 August 2012
NCT00476242 Completed Phase 2/Phase 3 Memantine as a Supplement to Naltrexone in Treating Heroin Dependence June 2008 August 2011
NCT00577408 Completed Phase 3 Behavioral Naltrexone Therapy for Promoting Adherence to Oral Naltrexone vs Extended Release Injectable Depot Naltrexone September 2007 August 2011
NCT03711318 Terminated Phase 3 Buprenorphine Stabilization and Induction Onto Vivitrol for Heroin-dependent Individuals November 1, 2018 December 31, 2021
NCT01395797 Terminated Phase 1/Phase 2 Pioglitazone for Heroin and for Nicotine Dependence March 2011 June 2014
NCT00609089 Unknown status Phase 1/Phase 2 Community Reinforcement and Family Training for Drug Abuse Treatment Retention/HIV Risk Reduction March 2008 June 2013
NCT03229642 Unknown status N/A Repetitive Transcranial Magnetic Stimulation in Patients With Opioid Use Disorders August 1, 2017 December 31, 2022
NCT03557632 Unknown status N/A University of Houston Drug Abuse Research Development Program II August 1, 2014 March 31, 2020
NCT01144390 Unknown status N/A Effect Study of Optimized Intervention to Heroin Addicts April 2010 June 2011
NCT02524912 Unknown status Methadone Maintenance Outcome Study in Taiwan: 5-year Follow-up April 2015 March 2017
NCT02541500 Unknown status Phase 3 An Open Label Study of Oral Minocycline for the Treatment of Patients With Co-occurring Opioid and ATS Dependence April 2013 January 2017
NCT02541513 Unknown status Phase 3 An Open-label Study of Oral Paliparidone for the Treatment of Patients With Co-occurring Opioid and ATS Dependence May 2013 January 2017
NCT02541526 Unknown status Phase 3 Mirtazapine as a Treatment for Co-Occurring Opioid and ATS Dependence in Malaysia May 2013 May 2017
NCT03922659 Unknown status N/A Efficacy of Repetitive Transcranial Magnetic Stimulation and Cognitive Behavioral Therapy on Heroin Dependence June 30, 2019 December 2021
NCT04003077 Unknown status N/A Laser Meridian Massage in Heroin Addicts February 26, 2019 April 16, 2020
NCT00726960 Unknown status Phase 1 Ability of Aprepitant to Block Opioid Reward in Non-Dependent Opiate Abusers January 2008 June 2010
NCT00000329 Withdrawn Phase 2 Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment II-1 - 4 April 1999 August 1999
NCT00000330 Withdrawn Phase 2 Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment II-2 - 5 October 1999 November 1999
NCT00000331 Withdrawn Phase 2 Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment II-3 - 6 December 2002 December 2002
NCT00000328 Withdrawn Phase 2 Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment III) - 3 July 1997 August 1997
NCT00000326 Withdrawn Phase 2 Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment 1 - 1 April 1997 August 1997
NCT00000327 Withdrawn Phase 2 Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment I(2) - 2 June 1997 August 1997
NCT00709007 Withdrawn Phase 2/Phase 3 Directly Administered Antiretroviral Therapy (DAART) Among HIV-1infected Injecting Drug Users (IDUs) in Chennai, India July 2008 July 2011
Disase is a (Disease Ontology)
DOID:2559
Cross Reference ID (Disease Ontology)
MESH:D006556
Cross Reference ID (Disease Ontology)
NCI:C34694
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:191817000
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0019337
MeSH unique ID (MeSH (Medical Subject Headings))
D006556