Annotation Detail
Information
- Associated Genes
- SLC6A4
- Associated Variants
-
SLC6A4 MUTATION
SLC6A4 MUTATION - Associated Disease
- Mental Depression
- Source Database
- DisGeNET
- Description
- The low activity variants of the 5-HTT-linked polymorphic region in the serotonin transporter gene and the Met-allele of a single nucleotide polymorphism (Val66Met) in the gene encoding brain derived neurotrophic factor were independently associated with the presence of stressful life events prior to onset of depression, also when corrected for the effect of age, gender, marital status, personality disorder, neuroticism, and severity of depressive symptoms at the time of interview.
- Pubmed
- 19339052
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.154646514822083
- Year of publication
- 2009
Drugs