Annotation Detail

Information
Associated Genes
SLC6A4
Associated Variants
SLC6A4 MUTATION
SLC6A4 MUTATION
Associated Disease
pulmonary hypertension
Source Database
DisGeNET
Description
Chronic imetelstat treatment reduced hypoxia-induced PH in wild-type mice or partially reversed established PH in SM22-5HTT(+) mice while simultaneously decreasing TERT expression.
Pubmed
25550449
Section of the abstract supporting the evidence
METHODS AND RESULTS
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
9
Original source reporting the Gene Disease association
BeFree,CTD_human,GAD,LHGDN,RGD
DisGENET score for the Gene Disease association
0.222451187469134
Drugs