congenital heart defects

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Information
Disease name
congenital heart defects
Disease ID
Description
Disease area statistics
Chromosome band
Gene symbol Chromosome Start Stop The number of variant
CDK13 7 39,950,256 40,099,580 4
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT00740870 Completed N/A Melody Transcatheter Pulmonary Valve Study: Post Approval Study of the Investigational Device Exemption Cohort January 2007 August 21, 2020
NCT00112424 Completed N/A Trial of Cardiac Magnetic Resonance Imaging (MRI) Versus Cardiac Catheterization Prior to Glenn Operation January 2004 January 2008
NCT00115375 Completed Phase 2 Platelet Aggregation Inhibition in Children on Clopidogrel (PICOLO) January 2004 April 2006
NCT00397514 Completed Assessing the Hemodynamic Benefits of Cardiac Resynchronization Therapy in Children Following Open-Heart Surgery October 2006 November 2009
NCT00446927 Completed SPY Imaging System: Its Role in Pediatric Cardiac Surgery April 2007 January 2012
NCT00450684 Completed Phase 2/Phase 3 Cardiac Resynchronization Therapy in Congenital Heart Defects May 2007 September 2013
NCT00608556 Completed Dyskinesia, Heterotaxy and Congenital Heart Disease January 25, 2008 October 31, 2011
NCT00006186 Completed N/A Autologous Fresh Whole Blood and Coagulation Following Cardiopulmonary Bypass in Infants
NCT00883922 Completed Central Venous Saturation (ScvO2) Monitoring in Pediatric Patients Undergoing Cardiac Surgery March 2007 March 2010
NCT00974688 Completed N/A Optimizing Health Among Children With Congenital Heart Defects July 2009 June 2012
NCT01032876 Completed N/A Cerebral Perfusion During Neonatal Cardiac Surgery January 2009 June 2012
NCT01201486 Completed Use of Color Doppler in Routine Examination of Fetal Heart in Second Trimester October 2006 August 2009
NCT01286480 Completed N/A Congenital Heart Adolescents: Program of Transition Evaluation Research January 2011 December 2013
NCT01475357 Completed N/A Intestinal Function in Neonates With Complex Congenital Heart Disease October 2011 April 2014
NCT01489475 Completed Plasma Angiopoietin Levels in Children Following Cardiopulmonary Bypass November 2011 June 2013
NCT01567579 Completed An Evaluation of Routine Developmental Follow-Up in Infants and Children With Congenital Heart Disease September 2009 September 2021
NCT01662037 Completed Phase 2 Bosentan Therapy in Children With Functional Single Ventricle January 2010 June 2012
NCT01671566 Completed N/A Interval Training in Adults With Congenital Heart Disease a Randomized Trial September 2012 March 2016
NCT01785498 Completed N/A Healthy Lifestyles for Children With Complex Heart Problems January 2012 October 2013
NCT01845402 Completed Chronic Kidney Disease in Teenagers With Congenital Cardiac Disease April 2, 2013 June 20, 2015
NCT01941576 Completed N/A Effects of rhBNP in Pediatrics After Corrective Repair of Tetralogy Of Fallot September 1, 2013 July 20, 2019
NCT02232399 Completed Phase 2 Is Levosimendan Superior to Milrinone Regarding Acute Kidney Injury After Cardiac Surgery for Congenital Heart Disease? October 15, 2014 April 25, 2017
NCT02320669 Completed Phase 3 Phase 3 Triiodothyronine Supplementation for Infants After Cardiopulmonary Bypass November 2014 October 2019
NCT02417259 Completed Near Infrared Spectroscopy in Cyanotic Congenital Heart Disease July 2015 April 2018
NCT02555319 Completed N/A A Feasibility Study to Evaluate the Safety and Short-term Effectiveness of Transcatheter Pulmonary Valve (TPV) August 26, 2015 October 25, 2021
NCT02615262 Completed Phase 3 Intraoperative Dexamethasone in Pediatric Cardiac Surgery December 2015 December 2018
NCT02766998 Completed N/A Preserved Umbilical Vein Use as Autologous Shunt Conduits in Neonatal Cardiac Surgery May 16, 2016 November 15, 2021
NCT03724006 Completed N/A Impact of Psychoeducation in Quality of Life of Parents With Children With Congenital Heart Defects March 7, 2019 February 28, 2020
NCT05191654 Completed Investigation of Cardiopulmonary Parameters, Motor Development and Muscle Strength in DS With and Without CHD October 1, 2020 June 30, 2021
NCT00226369 Completed Phase 2/Phase 3 Cylexin for Reduction of Reperfusion Injury in Infant Heart Surgery December 1997 June 2001
NCT00266201 Completed Right Ventricular Failure in Congenital Heart Defects June 2003 July 2006
NCT05195788 Enrolling by invitation N/A Cardiac Rehabilitation in Congenital Heart Disease: Effects on Brain and Cognitive Functions February 7, 2022 April 2024
NCT06442592 Not yet recruiting N/A Characterization and Support for Neurodevelopmental Disorders Associated With Congenital Heart Defects July 1, 2024 August 1, 2025
NCT05457712 Not yet recruiting N/A Nutrition In Preoperative Pediatric Congenital Heart Disease January 9, 2023 May 2, 2024
NCT06124443 Not yet recruiting Congenital Heart Defects December 1, 2024 May 31, 2026
NCT01196182 Recruiting Congenital Heart Disease GEnetic NEtwork Study (CHD GENES) November 15, 2010 December 2025
NCT02923440 Recruiting N/A Creation of a French South-Eastern Database and DNA-bank of Congenital Heart Disease to Explore the Genetic Pathways January 17, 2017 March 2028
NCT06267859 Recruiting Early Phase 1 Development of Methods for Effective Treatment and Improvement of Common Somatic Diseases in Children November 8, 2023 January 30, 2034
NCT03822442 Recruiting MRI to Predict Rejection and Failure in Transplant and Cardiomyopathy Patients November 1, 2019 December 31, 2024
NCT02432079 Recruiting Molecular Genetics of Heterotaxy and Related Congenital Heart Defects July 2009 December 2030
NCT04208893 Suspended N/A Exercise Training Strategies for Children With Repaired Tetralogy of Fallot August 20, 2019 August 31, 2022
NCT00208676 Terminated Using Tissue Doppler/Synchronization to Determine Heart Function in Children With Congenital Heart Disease September 2005 January 2006
NCT00208754 Terminated Heart Failure in Adult Patients With a History of Congenital Heart Disease May 2004 December 2005
NCT00215072 Terminated Death Following Congenital Heart Surgery July 2005 February 2007
NCT00278005 Terminated Infection in DiGeorge Following CHD Surgery January 1998 March 2008
NCT02632253 Terminated N/A Effects of High-intensity Interval Training on Exercise Capacity in Patients With Grown-up Congenital Heart Disease January 2016 October 2019
NCT03630796 Unknown status Phase 4 Effect of Sevoflurane in Postoperative Troponin I Levels in Children Undergoing Congenital Heart Defects Surgery August 20, 2018 December 2019
NCT00921596 Unknown status Phase 1/Phase 2 Cardiac Operation Under Totally Endoscope and Cardiopulmonary Bypass (CPB) January 2000 December 2009
NCT02395276 Unknown status N/A Hypothermia Therapy in Pediatric Cardiac Intensive Care Unit for Suspected for Brain Injury April 2015 April 2020
NCT04382573 Unknown status Better Delineation of CDK13 Related Phenotype and Epigenetic Signature. November 1, 2019 December 30, 2020
NCT01227096 Unknown status Randomized Controlled Trial of the Effects of Electroacupuncture Preconditioning in Children Undergoing Cardiac Surgery October 2010 July 2011
NCT02475863 Unknown status N/A Model-based Versus Traditional Warfarin Dosing in Children August 2015 January 2018
NCT01421030 Unknown status Early Phase 1 Outcomes in Patients and Their Closest Relatives Treated for Congenital Heart Disease With Catheter Based or Surgical Techniques September 2011 September 2014
NCT02928133 Unknown status NOACs for Atrial Tachyarrhythmias in Congenital Heart Disease April 2014
NCT02752399 Unknown status Six Minutes Walk Test and Shuttle Walk Test in Eisenmenger Syndrome April 2016 June 2017
NCT00579358 Withdrawn Molecular Basis of Congenital Heart Defects November 2007 November 2007
NCT00981591 Withdrawn Phase 1/Phase 2 Inhaled Iloprost as an Adjunct to Inhaled Nitric Oxide in Pediatric Critical Care Patients September 2009 March 2013