chr2:190908460:> Detail (hg38)
Information
Genome
| Assembly | Position |
|---|---|
| hg19 | chr2:191,773,186-191,878,957 |
| hg38 | chr2:190,908,460-191,014,231 |
HGVS
| Type | Transcript | Protein |
|---|---|---|
Summary
MGeND
| Clinical significance | |
| Variant entry | |
| GWAS entry | |
| Disease area statistics | Show details |
Frequency
[No Data.]
Prediction
[No Data.]
ClinVar
| Clinical Significance | |
| Review star | [No Data.] |
| Show details | |
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
| Score | Disease name | Description | Source | Pubmed | Links |
|---|---|---|---|---|---|
| 0.001 | squamous cell carcinoma | NA | BeFree | Detail | |
| 0.003 | celiac disease | NA | BeFree,LHGDN | Detail | |
| 0.003 | choriocarcinoma | NA | LHGDN | Detail | |
| <0.001 | ulcerative colitis | NA | BeFree | Detail | |
| 0.003 | Colonic Neoplasms | NA | LHGDN | Detail | |
| <0.001 | colorectal carcinoma | NA | BeFree | Detail | |
| <0.001 | Crohn Disease | NA | BeFree | Detail | |
| 0.003 | cystic fibrosis | NA | LHGDN | Detail | |
| 0.120 | Cytomegalovirus Infections | NA | CTD_human | Detail | |
| <0.001 | Presenile dementia | NA | BeFree | Detail | |
| <0.001 | dermatomyositis | NA | BeFree | Detail | |
| <0.001 | Diabetes | The microarray data suggested significantly increased expression of interleukin-... | BeFree | 26228595 | Detail |
| <0.001 | diabetes mellitus | The microarray data suggested significantly increased expression of interleukin-... | BeFree | 26228595 | Detail |
| 0.080 | Diabetes Mellitus, Experimental | NA | RGD | Detail | |
| <0.001 | Diabetes Mellitus, Insulin-Dependent | NA | BeFree | Detail | |
| <0.001 | Diabetic Nephropathy | NA | BeFree | Detail | |
| <0.001 | Down syndrome | NA | BeFree | Detail | |
| <0.001 | Dwarfism | NA | BeFree | Detail | |
| <0.001 | eclampsia | NFAT-1, STAT-1 and AP-1 might be the central transcription factors in the pathog... | BeFree | 24931237 | Detail |
| <0.001 | Fanconi anemia | NA | BeFree | Detail | |
| <0.001 | fibrosarcoma | NA | BeFree | Detail | |
| 0.003 | Fibrosis | NA | LHGDN | Detail | |
| <0.001 | Giant Cell Tumors | NA | BeFree | Detail | |
| <0.001 | Gingival Diseases | NA | BeFree | Detail | |
| 0.006 | glioblastoma | NA | BeFree,GAD,LHGDN | Detail | |
| 0.003 | Glioma | NA | BeFree,GAD | Detail | |
| <0.001 | glomerulonephritis | NA | BeFree | Detail | |
| <0.001 | IgA glomerulonephritis | NA | BeFree | Detail | |
| <0.001 | Graft-vs-Host Disease | The major polyphenol of green tea, epigallocatechin-3-gallate (EGCG), is an inhi... | BeFree | 23676554 | Detail |
| 0.003 | hepatitis B | NA | BeFree,GAD | Detail | |
| <0.001 | Hepatitis, Chronic | NA | BeFree | Detail | |
| 0.006 | hepatitis C | NA | BeFree,GAD,LHGDN | Detail | |
| <0.001 | Herpes NOS | NA | BeFree | Detail | |
| 0.004 | HIV Infections | NA | BeFree | Detail | |
| 0.003 | hyperinsulinism | NA | LHGDN | Detail | |
| 0.002 | Immediate hypersensitivity | NA | GAD | Detail | |
| <0.001 | hypothyroidism | NA | BeFree | Detail | |
| 0.120 | influenza | NA | CTD_human | Detail | |
| <0.001 | insulinoma | NA | BeFree | Detail | |
| <0.001 | ischemia | NA | BeFree | Detail | |
| <0.001 | leukemia | NA | BeFree | Detail | |
| 0.004 | chronic lymphocytic leukemia | NA | BeFree,LHGDN | Detail | |
| 0.003 | Acute Erythroblastic Leukemia | NA | BeFree,LHGDN | Detail | |
| <0.001 | Acute lymphocytic leukemia | NA | BeFree | Detail | |
| <0.001 | Leukemia, Myelocytic, Acute | NA | BeFree | Detail | |
| 0.003 | myeloid leukemia | NA | BeFree,GAD | Detail | |
| 0.004 | Myeloid Leukemia, Chronic | NA | BeFree,LHGDN | Detail | |
| <0.001 | acute promyelocytic leukemia | NA | BeFree | Detail | |
| <0.001 | Leukemia, T-Cell | NA | BeFree | Detail | |
| <0.001 | Adult T-Cell Lymphoma/Leukemia | Our results suggest that therapeutic approaches using combined targeting of STAT... | BeFree | 26025667 | Detail |
| <0.001 | Leukoencephalopathy, Progressive Multifocal | NA | BeFree | Detail | |
| 0.123 | liver cirrhosis | NA | BeFree,CTD_human,GAD | Detail | |
| 0.004 | Liver neoplasms | NA | BeFree,GAD | Detail | |
| 0.003 | Chronic Obstructive Airway Disease | NA | BeFree,GAD | Detail | |
| <0.001 | Lupus Vulgaris | NA | BeFree | Detail | |
| <0.001 | Lupus Erythematosus, Discoid | NA | BeFree | Detail | |
| <0.001 | lupus nephritis | NA | BeFree | Detail | |
| <0.001 | lymphocytic choriomeningitis | NA | BeFree | Detail | |
| 0.004 | lymphoma | NA | BeFree,LHGDN | Detail | |
| 0.003 | Lymphoma, Follicular | Structural modeling of STAT6 based on the structure of the STAT1-DNA complex rev... | BeFree,LHGDN | 25428220 | Detail |
| <0.001 | Malignant neoplasm of stomach | NA | BeFree | Detail | |
| <0.001 | measles | NA | BeFree | Detail | |
| 0.006 | melanoma | NA | BeFree,LHGDN | Detail | |
| <0.001 | Mesothelioma | NA | BeFree | Detail | |
| <0.001 | Monosomy | NA | BeFree | Detail | |
| <0.001 | Mucocutaneous Lymph Node Syndrome | NA | BeFree | Detail | |
| 0.001 | multiple myeloma | NA | BeFree | Detail | |
| 0.008 | multiple sclerosis | NA | BeFree,GAD,LHGDN | Detail | |
| 0.003 | mumps | NA | BeFree,LHGDN | Detail | |
| 0.123 | Mycobacterium Infections | NA | BeFree,CTD_human | Detail | |
| 0.120 | Mycobacterium Infections, Nontuberculous | NA | CTD_human | Detail | |
| 0.001 | Mycoses | The current studies demonstrate that infection with C. neoformans strain H99γ in... | BeFree | 26351277 | Detail |
| 0.080 | Myocardial Reperfusion Injury | NA | RGD | Detail | |
| 0.001 | Neoplasm Metastasis | Targeting EGF-receptor(s) - STAT1 axis attenuates tumor growth and metastasis th... | BeFree | 25686822 | Detail |
| <0.001 | nephroblastoma | NA | BeFree | Detail | |
| <0.001 | neuroblastoma | NA | BeFree | Detail | |
| 0.002 | neutropenia | NA | GAD | Detail | |
| <0.001 | Degenerative polyarthritis | NA | BeFree | Detail | |
| <0.001 | osteomyelitis | NA | BeFree | Detail | |
| 0.003 | osteoporosis | NA | BeFree,GAD | Detail | |
| <0.001 | ovarian carcinoma | NA | BeFree | Detail | |
| <0.001 | Parainfluenza | NA | BeFree | Detail | |
| <0.001 | Periodontal Diseases | NA | BeFree | Detail | |
| <0.001 | plasmacytoma | NA | BeFree | Detail | |
| <0.001 | polycythemia vera | NA | BeFree | Detail | |
| 0.003 | Prostatic Neoplasms | NA | LHGDN | Detail | |
| 0.080 | pulmonary fibrosis | NA | RGD | Detail | |
| <0.001 | Rabies (disorder) | NA | BeFree | Detail | |
| <0.001 | Reoviridae Infections | NA | BeFree | Detail | |
| 0.080 | Reperfusion Injury | NA | RGD | Detail | |
| 0.003 | Respiratory Syncytial Virus Infections | NA | BeFree,GAD | Detail | |
| <0.001 | Respiratory Tract Infections | NA | BeFree | Detail | |
| 0.002 | Salmonella infections | NA | GAD | Detail | |
| <0.001 | scleritis | NA | BeFree | Detail | |
| <0.001 | Cerebrovascular accident | NA | BeFree | Detail | |
| <0.001 | synovitis | NA | BeFree | Detail | |
| <0.001 | thanatophoric dysplasia | NA | BeFree | Detail | |
| 0.002 | thrombocytopenia | NA | GAD | Detail | |
| <0.001 | thymoma | NA | BeFree | Detail | |
| 0.002 | Thyroid Neoplasm | NA | GAD | Detail | |
| 0.002 | Tobacco use disorder | NA | GAD | Detail | |
| <0.001 | Chagas disease | Furthermore, we found that in response to T. cruzi the total amount of intracell... | BeFree | 25340519 | Detail |
| 0.003 | tuberculosis | NA | BeFree,GAD | Detail | |
| <0.001 | uveitis | NA | BeFree | Detail | |
| <0.001 | varicocele | Subjects with varicocele demonstrated a significant negative correlation between... | BeFree | 26209830 | Detail |
| <0.001 | Vascular Diseases | Data mining of atherosclerotic plaque transcriptomes predicts STAT1-dependent in... | BeFree | 25196434 | Detail |
| 0.002 | Viremia | NA | GAD | Detail | |
| 0.007 | Virus Diseases | NA | BeFree,LHGDN | Detail | |
| 0.003 | diffuse large B-cell lymphoma | NA | BeFree,GAD | Detail | |
| <0.001 | Lymphoma, T-Cell, Cutaneous | NA | BeFree | Detail | |
| 0.002 | Arthritis, Reactive | NA | GAD | Detail | |
| <0.001 | acute leukemia | NA | BeFree | Detail | |
| <0.001 | Sicca Syndrome | NA | BeFree | Detail | |
| <0.001 | Squamous cell carcinoma of lung | NA | BeFree | Detail | |
| <0.001 | Primary Sj�gren's syndrome | The expression and phosphorylation of signal transducer and activator of transcr... | BeFree | 25736842 | Detail |
| <0.001 | renal fibrosis | NA | BeFree | Detail | |
| <0.001 | Acute miliary tuberculosis | NA | BeFree | Detail | |
| <0.001 | Non-arthropod borne lymphocytic choriomeningitis | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of mouth | B-cell lymphoma/leukemia 10 promotes oral cancer progression through STAT1/ATF4/... | BeFree | 24681956 | Detail |
| <0.001 | Malignant neoplasm of nasopharynx | NA | BeFree | Detail | |
| <0.001 | Aortic Aneurysm, Abdominal | NA | BeFree | Detail | |
| 0.001 | Tumor Progression | NA | BeFree | Detail | |
| <0.001 | Dysplastic Nevus | NA | BeFree | Detail | |
| <0.001 | Ki-1+ Anaplastic Large Cell Lymphoma | Thus, STAT1 is a tumor suppressor in ALK+ ALCL. | BeFree | 25921060 | Detail |
| 0.002 | Medullary carcinoma | NA | GAD | Detail | |
| <0.001 | Lip and oral cavity carcinoma | B-cell lymphoma/leukemia 10 promotes oral cancer progression through STAT1/ATF4/... | BeFree | 24681956 | Detail |
| <0.001 | diastrophic dysplasia | NA | BeFree | Detail | |
| <0.001 | Adult type dermatomyositis | NA | BeFree | Detail | |
| <0.001 | pancreatic carcinoma | Suppression of Tyk2 and Stat1, which are important downstream molecules for IFN-... | BeFree | 25727013 | Detail |
| <0.001 | Cancer of Nasopharynx | NA | BeFree | Detail | |
| 0.003 | Malignant neoplasm of lung | These results suggest that the upregulation of Stat1 and HDAC4 determines etopos... | BeFree,GAD | 25395162 | Detail |
| 0.120 | Disease Progression | NA | CTD_human | Detail | |
| 0.080 | Sepsis | NA | RGD | Detail | |
| <0.001 | Atresia | NA | BeFree | Detail | |
| <0.001 | Vesicular Stomatitis | In contrast, tumor-derived Pten(-/-) cells expressed higher levels of the antivi... | BeFree | 25741004 | Detail |
| <0.001 | Herpes encephalitis | NA | BeFree | Detail | |
| <0.001 | Disease due to Parvoviridae | Suppression of Tyk2 and Stat1, which are important downstream molecules for IFN-... | BeFree | 25727013 | Detail |
| <0.001 | Malignant neoplasm of stomach stage IV | Among these genes, STAT1 and EGR2 may constitute potential biomarkers of GC meta... | BeFree | 25334039 | Detail |
| <0.001 | Metastatic melanoma | NA | BeFree | Detail | |
| <0.001 | Cancer of Head and Neck | NA | BeFree | Detail | |
| 0.001 | Squamous cell carcinoma of esophagus | The clinical and biological significance of STAT1 in esophageal squamous cell ca... | BeFree | 25355139 | Detail |
| <0.001 | stage, neuroblastoma | NA | BeFree | Detail | |
| <0.001 | cervix carcinoma | The increase of the expression of type I interferon (IFN) and its classical effe... | BeFree | 25265013 | Detail |
| <0.001 | Tumor necrosis | NA | BeFree | Detail | |
| <0.001 | Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse | NA | BeFree | Detail | |
| <0.001 | Stable angina | NA | BeFree | Detail | |
| <0.001 | Dissection of aorta | NA | BeFree | Detail | |
| <0.001 | eosinophilic esophagitis | NA | BeFree | Detail | |
| <0.001 | Chondrodysplasia | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of pancreas | Suppression of Tyk2 and Stat1, which are important downstream molecules for IFN-... | BeFree | 25727013 | Detail |
| <0.001 | Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of prostate | Activation of proliferation promoting signaling pathways (including β-catenin, c... | BeFree | 25566960 | Detail |
| <0.001 | Primary immune deficiency disorder | Chronic mucocutaneous candidiasis (CMC) and hyper-IgE syndrome (HIES) are primar... | BeFree | 23796786 | Detail |
| <0.001 | lupus erythematosus | NA | BeFree | Detail | |
| <0.001 | Skeletal dysplasia | NA | BeFree | Detail | |
| <0.001 | pricking of skin | NA | BeFree | Detail | |
| <0.001 | Disseminated due to other mycobacteria | NA | BeFree | Detail | |
| <0.001 | dementia | NA | BeFree | Detail | |
| <0.001 | Chronic active hepatitis | NA | BeFree | Detail | |
| 0.003 | Hepatitis B, Chronic | NA | BeFree,GAD | Detail | |
| 0.008 | Hepatitis C, Chronic | NA | BeFree,GAD | Detail | |
| <0.001 | Oropharyngeal disorders | NA | BeFree | Detail | |
| <0.001 | Malignant glioma | NA | BeFree | Detail | |
| <0.001 | Carotid Atherosclerosis | Moreover, using data mining of human plaque transcriptomes, expression of a sele... | BeFree | 25478796 | Detail |
| 0.004 | Carcinogenesis | The current study was designed to explore the role of signal transducer and acti... | BeFree | 24464587 | Detail |
| 0.004 | Carcinogenesis | Phosphorylation and downregulation of STAT1 by NPM-ALK represent other mechanism... | BeFree | 25921060 | Detail |
| <0.001 | prostate carcinoma | Activation of proliferation promoting signaling pathways (including β-catenin, c... | BeFree | 25566960 | Detail |
| <0.001 | Epithelial ovarian cancer | NA | BeFree | Detail | |
| 0.003 | breast carcinoma | NA | BeFree | Detail | |
| <0.001 | Carcinoma of lung | These results suggest that the upregulation of Stat1 and HDAC4 determines etopos... | BeFree | 25395162 | Detail |
| <0.001 | polycythemia vera | Activated STAT1 and STAT5 transcription factors in extramedullary hematopoietic ... | BeFree | 20013324 | Detail |
| 0.002 | colon carcinoma | NA | BeFree | Detail | |
| <0.001 | stomach carcinoma | NA | BeFree | Detail | |
| <0.001 | Carcinoma of bladder | NA | BeFree | Detail | |
| <0.001 | Central neuroblastoma | NA | BeFree | Detail | |
| <0.001 | Carotid Artery Plaque | The results of our in silico analysis in vitro provide potential evidence that S... | BeFree | 25196434 | Detail |
| 0.080 | Trauma, Nervous System | NA | RGD | Detail | |
| <0.001 | malignant pleural mesothelioma | NA | BeFree | Detail | |
| <0.001 | Endothelial dysfunction | NA | BeFree | Detail | |
| <0.001 | Spondylarthritis | NA | BeFree | Detail | |
| 0.200 | Arthritis, Experimental | NA | CTD_human,RGD | Detail | |
| <0.001 | West Nile viral infection | NA | BeFree | Detail | |
| 0.003 | Malignant neoplasm of ovary | NA | BeFree,GAD | Detail | |
| <0.001 | Squamous cell carcinoma of the head and neck | NA | BeFree | Detail | |
| <0.001 | sarcoma | STAT1 showed a strong association with overall survival in UPS patients (logrank... | BeFree | 25188299 | Detail |
| <0.001 | Thanatophoric dysplasia, type 2 | NA | BeFree | Detail | |
| <0.001 | Anaplastic Large Cell Lymphoma, ALK-Positive | STAT1 is phosphorylated and downregulated by the oncogenic tyrosine kinase NPM-A... | BeFree | 25921060 | Detail |
| <0.001 | Invasive Carcinoma | NA | BeFree | Detail | |
| <0.001 | Systemic onset juvenile chronic arthritis | NA | BeFree | Detail | |
| 0.120 | hearing impairment | NA | CTD_human | Detail | |
| 0.004 | Mammary Neoplasms | NA | BeFree,LHGDN | Detail | |
| <0.001 | Neuropathogenesis | NA | BeFree | Detail | |
| <0.001 | Tumor Promotion | The current study was designed to explore the role of signal transducer and acti... | BeFree | 24464587 | Detail |
| <0.001 | colorectal cancer | NA | BeFree | Detail | |
| 0.003 | Sjogren's syndrome | NA | LHGDN | Detail | |
| <0.001 | Glioblastoma multiforme | NA | BeFree | Detail | |
| <0.001 | Cirrhosis | NA | BeFree | Detail | |
| <0.001 | T-lymphocyte deficiency | NA | BeFree | Detail | |
| <0.001 | IMMUNE SUPPRESSION | NA | BeFree | Detail | |
| <0.001 | THANATOPHORIC DYSPLASIA, TYPE I (disorder) | NA | BeFree | Detail | |
| <0.001 | coronary artery disease | Moreover, using data mining of human plaque transcriptomes, expression of a sele... | BeFree | 25478796 | Detail |
| <0.001 | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma | NA | BeFree | Detail | |
| <0.001 | Precursor Cell Lymphoblastic Leukemia Lymphoma | NA | BeFree | Detail | |
| 0.126 | liver carcinoma | We found that aberrant proteolysis appeared to occur frequently during recurrenc... | BeFree,CTD_human,GAD | 24967658 | Detail |
| <0.001 | Promyelocytic leukemia | NA | BeFree | Detail | |
| <0.001 | Human Papillomavirus Positive Oropharyngeal Squamous Cell Carcinoma | NA | BeFree | Detail | |
| <0.001 | Nasopharyngeal carcinoma | NA | BeFree | Detail | |
| <0.001 | FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder) | NA | BeFree | Detail | |
| <0.001 | Juvenile arthritis | This analysis revealed the genes of greatest potential functional importance to ... | BeFree | 24886659 | Detail |
| <0.001 | Triple Negative Breast Neoplasms | NA | BeFree | Detail | |
| <0.001 | Allergic disposition | NA | BeFree | Detail | |
| 0.016 | Infection | NA | LHGDN | Detail | |
| <0.001 | juvenile rheumatoid arthritis | This analysis revealed the genes of greatest potential functional importance to ... | BeFree | 24886659 | Detail |
| <0.001 | Disseminated Bacillus Calmette-Guerin Infection | NA | BeFree | Detail | |
| 0.240 | immunodeficiency 31A | NA | ORPHANET,UNIPROT | Detail | |
| <0.001 | Congenital Abnormality | NA | BeFree | Detail | |
| <0.001 | adenocarcinoma | NA | BeFree | Detail | |
| <0.001 | anemia | NA | BeFree | Detail | |
| <0.001 | Refractory anaemia with excess blasts | NA | BeFree | Detail | |
| <0.001 | Aneurysm | NA | BeFree | Detail | |
| 0.005 | Anoxia | NA | LHGDN | Detail | |
| <0.001 | aortic aneurysm | NA | BeFree | Detail | |
| <0.001 | Aortic Rupture | NA | BeFree | Detail | |
| 0.001 | arteriosclerosis | The results of our in silico analysis in vitro provide potential evidence that S... | BeFree | 25196434 | Detail |
| 0.001 | arteriosclerosis | STAT1-dependent signal integration between IFNγ and TLR4 in vascular cells refle... | BeFree | 25478796 | Detail |
| 0.122 | rheumatoid arthritis | Our results suggest that in RA miR-146a facilitates a pro-inflammatory phenotype... | BeFree,CTD_human | 24562503 | Detail |
| 0.004 | asthma | NA | BeFree,GAD | Detail | |
| 0.001 | atherosclerosis | The results of our in silico analysis in vitro provide potential evidence that S... | BeFree | 25196434 | Detail |
| 0.001 | atherosclerosis | STAT1-dependent signal integration between IFNγ and TLR4 in vascular cells refle... | BeFree | 25478796 | Detail |
| <0.001 | Bacterial Infections | NA | BeFree | Detail | |
| <0.001 | biliary atresia | NA | BeFree | Detail | |
| 0.003 | Malignant neoplasm of urinary bladder | NA | BeFree,GAD | Detail | |
| 0.003 | Bladder Neoplasm | NA | LHGDN | Detail | |
| <0.001 | Brain Neoplasms | NA | BeFree | Detail | |
| 0.006 | Malignant neoplasm of breast | NA | BeFree,GAD | Detail | |
| 0.002 | Bronchiolitis, Viral | NA | GAD | Detail | |
| 0.002 | Campylobacter infection | NA | GAD | Detail | |
| <0.001 | candidiasis | Defective trained immunity in patients with STAT-1-dependent chronic mucocutanea... | BeFree | 25880788 | Detail |
| 0.244 | Candidiasis, Chronic Mucocutaneous | Chronic mucocutaneous candidiasis (CMC) and hyper-IgE syndrome (HIES) are primar... | BeFree,CTD_human,ORPHANET | 23796786 | Detail |
| 0.244 | Candidiasis, Chronic Mucocutaneous | These findings describe the role of STAT-1 for the induction of trained immunity... | BeFree,CTD_human,ORPHANET | 25880788 | Detail |
| 0.244 | Candidiasis, Chronic Mucocutaneous | Gain-of-function STAT1 mutations impair STAT3 activity in patients with chronic ... | BeFree,CTD_human,ORPHANET | 26255980 | Detail |
| 0.002 | Malignant tumor of colon | NA | BeFree | Detail | |
| <0.001 | Noninfiltrating Intraductal Carcinoma | NA | BeFree | Detail | |
| <0.001 | Non-small cell lung carcinoma | NA | BeFree | Detail | |
| <0.001 | renal cell carcinoma | NA | BeFree | Detail |
Annotation
Annotations
| Descrption | Source | Links |
|---|---|---|
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
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| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The microarray data suggested significantly increased expression of interleukin-6 R, proapoptotic p-... | DisGeNET | Detail |
| The microarray data suggested significantly increased expression of interleukin-6 R, proapoptotic p-... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NFAT-1, STAT-1 and AP-1 might be the central transcription factors in the pathogenesis of pre-eclamp... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The major polyphenol of green tea, epigallocatechin-3-gallate (EGCG), is an inhibitor of both DNA me... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
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| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Our results suggest that therapeutic approaches using combined targeting of STAT1 and MHC class I ma... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Structural modeling of STAT6 based on the structure of the STAT1-DNA complex revealed that most FL-a... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The current studies demonstrate that infection with C. neoformans strain H99γ in mice with macrophag... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Targeting EGF-receptor(s) - STAT1 axis attenuates tumor growth and metastasis through downregulation... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
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| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
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| Furthermore, we found that in response to T. cruzi the total amount of intracellular STAT1 increased... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Subjects with varicocele demonstrated a significant negative correlation between head morphological ... | DisGeNET | Detail |
| Data mining of atherosclerotic plaque transcriptomes predicts STAT1-dependent inflammatory signal in... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
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| The expression and phosphorylation of signal transducer and activator of transcription-1 (STAT-1) ha... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| B-cell lymphoma/leukemia 10 promotes oral cancer progression through STAT1/ATF4/S100P signaling path... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Thus, STAT1 is a tumor suppressor in ALK+ ALCL. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| B-cell lymphoma/leukemia 10 promotes oral cancer progression through STAT1/ATF4/S100P signaling path... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Suppression of Tyk2 and Stat1, which are important downstream molecules for IFN-α signaling, sensiti... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| These results suggest that the upregulation of Stat1 and HDAC4 determines etoposide resistance throu... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| In contrast, tumor-derived Pten(-/-) cells expressed higher levels of the antiviral transcription fa... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Suppression of Tyk2 and Stat1, which are important downstream molecules for IFN-α signaling, sensiti... | DisGeNET | Detail |
| Among these genes, STAT1 and EGR2 may constitute potential biomarkers of GC metastasis. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The clinical and biological significance of STAT1 in esophageal squamous cell carcinoma. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The increase of the expression of type I interferon (IFN) and its classical effective molecules and ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Suppression of Tyk2 and Stat1, which are important downstream molecules for IFN-α signaling, sensiti... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Activation of proliferation promoting signaling pathways (including β-catenin, cMyc, NF-κB, STAT1, S... | DisGeNET | Detail |
| Chronic mucocutaneous candidiasis (CMC) and hyper-IgE syndrome (HIES) are primary immunodeficiencies... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Moreover, using data mining of human plaque transcriptomes, expression of a selection of these STAT1... | DisGeNET | Detail |
| The current study was designed to explore the role of signal transducer and activator of transcripti... | DisGeNET | Detail |
| Phosphorylation and downregulation of STAT1 by NPM-ALK represent other mechanisms by which this onco... | DisGeNET | Detail |
| Activation of proliferation promoting signaling pathways (including β-catenin, cMyc, NF-κB, STAT1, S... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| These results suggest that the upregulation of Stat1 and HDAC4 determines etoposide resistance throu... | DisGeNET | Detail |
| Activated STAT1 and STAT5 transcription factors in extramedullary hematopoietic tissue in a polycyth... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The results of our in silico analysis in vitro provide potential evidence that STAT1-dependent IFNγ-... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| STAT1 showed a strong association with overall survival in UPS patients (logrank p = 1.84 × 10(-6) a... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| STAT1 is phosphorylated and downregulated by the oncogenic tyrosine kinase NPM-ALK in ALK-positive a... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The current study was designed to explore the role of signal transducer and activator of transcripti... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Moreover, using data mining of human plaque transcriptomes, expression of a selection of these STAT1... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| We found that aberrant proteolysis appeared to occur frequently during recurrence of HCC in several ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| This analysis revealed the genes of greatest potential functional importance to be PTPN2 and STAT1 f... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| This analysis revealed the genes of greatest potential functional importance to be PTPN2 and STAT1 f... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The results of our in silico analysis in vitro provide potential evidence that STAT1-dependent IFNγ-... | DisGeNET | Detail |
| STAT1-dependent signal integration between IFNγ and TLR4 in vascular cells reflect pro-atherogenic r... | DisGeNET | Detail |
| Our results suggest that in RA miR-146a facilitates a pro-inflammatory phenotype of Tregs via increa... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The results of our in silico analysis in vitro provide potential evidence that STAT1-dependent IFNγ-... | DisGeNET | Detail |
| STAT1-dependent signal integration between IFNγ and TLR4 in vascular cells reflect pro-atherogenic r... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Defective trained immunity in patients with STAT-1-dependent chronic mucocutaneaous candidiasis. | DisGeNET | Detail |
| Chronic mucocutaneous candidiasis (CMC) and hyper-IgE syndrome (HIES) are primary immunodeficiencies... | DisGeNET | Detail |
| These findings describe the role of STAT-1 for the induction of trained immunity, and may contribute... | DisGeNET | Detail |
| Gain-of-function STAT1 mutations impair STAT3 activity in patients with chronic mucocutaneous candid... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
Overlapped Transcript Coordinates
| Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
|---|
Overlapped Transcript
| Gene | Transcript ID | Chromosome | Start | Stop | Links |
|---|
- Gene
- -
- dbSNP
- rs386626619 dbSNP
- Genome
- hg38
- Position
- chr2:190,908,460-191,014,231
- Variant Type
- snv
Genome browser