Annotation Detail

Information
Associated Genes
STAT1
Associated Variants
STAT1 MUTATION
STAT1 MUTATION
Associated Disease
rheumatoid arthritis
Source Database
DisGeNET
Description
Our results suggest that in RA miR-146a facilitates a pro-inflammatory phenotype of Tregs via increased STAT1 activation, and contributes thereby to RA pathogenesis.
Pubmed
24562503
Section of the abstract supporting the evidence
CONCLUSIONS
Number of the section of the abstract supporting the evidence
4
Number of the sentence supporting the evidence
11
Original source reporting the Gene Disease association
BeFree,CTD_human
DisGENET score for the Gene Disease association
0.122171534976642
Drugs