Annotation Detail
Information
- Associated Genes
- STAT1
- Associated Variants
-
STAT1 MUTATION
STAT1 MUTATION - Associated Disease
- cervix carcinoma
- Source Database
- DisGeNET
- Description
- The increase of the expression of type I interferon (IFN) and its classical effective molecules and the phosphorylation of signal transducers and activators of transcription (STAT1) protein indicated that miR-122 might enhance type I interferon in cervical carcinoma cells, which explained the significant reduction of HPV16 E7 and E6*I mRNA expression.
- Pubmed
- 25265013
- Section of the abstract supporting the evidence
- ALL_TEXT_2/3
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 6
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs