Annotation Detail
Information
- Associated Genes
- STAT1
- Associated Variants
-
STAT1 MUTATION
STAT1 MUTATION - Associated Disease
- Graft-vs-Host Disease
- Source Database
- DisGeNET
- Description
- The major polyphenol of green tea, epigallocatechin-3-gallate (EGCG), is an inhibitor of both DNA methyltransferase 1 (DNMT1) and signal transducer and activator of transcription 1 (STAT1), which are essential for induction of GvHD.
- Pubmed
- 23676554
- Section of the abstract supporting the evidence
- ALL_TEXT_2/3
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 2
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs