chr8:91013705:> Detail (hg19)
Information
Genome
| Assembly | Position |
|---|---|
| hg19 | chr8:91,013,705-91,065,861 |
| hg38 | chr8:90,001,477-90,053,633 |
HGVS
| Type | Transcript | Protein |
|---|---|---|
Summary
MGeND
| Clinical significance | |
| Variant entry | |
| GWAS entry | |
| Disease area statistics | Show details |
Frequency
[No Data.]
Prediction
[No Data.]
ClinVar
| Clinical Significance | |
| Review star | [No Data.] |
| Show details | |
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
| Score | Disease name | Description | Source | Pubmed | Links |
|---|---|---|---|---|---|
| <0.001 | Carcinoma, Transitional Cell | NA | BeFree | Detail | |
| 0.002 | Cardiovascular Diseases | Additional high-resolution studies in multiple vascular beds are required to add... | BeFree | 25239440 | Detail |
| <0.001 | Central Nervous System Infection | NA | BeFree | Detail | |
| <0.001 | intracranial aneurysm | NA | BeFree | Detail | |
| <0.001 | cerebral infarction | NA | BeFree | Detail | |
| <0.001 | colitis | NA | BeFree | Detail | |
| <0.001 | Colonic Neoplasms | NA | BeFree | Detail | |
| 0.002 | Coronary Arteriosclerosis | The observation by magnetic resonance imaging and computerized tomography of red... | BeFree | 25239440 | Detail |
| 0.002 | Coronary heart disease | NA | BeFree | Detail | |
| <0.001 | coronary artery vasospasm | NA | BeFree | Detail | |
| <0.001 | congenital hypothyroidism | A novel missense mutation (I26M) in DUOXA2 causing congenital goiter hypothyroid... | BeFree | 25675383 | Detail |
| <0.001 | Crohn Disease | Adherent-invasive E. coli LF82 induced ROS production by intestinal NADPH oxidas... | BeFree | 25822013 | Detail |
| <0.001 | scleroderma | Reactive oxygen species (ROS) contribute to the pathogenesis of fibrosis in syst... | BeFree | 25707572 | Detail |
| 0.002 | Diabetes | NA | BeFree | Detail | |
| 0.002 | diabetes mellitus | NA | BeFree | Detail | |
| 0.002 | Diabetes Mellitus, Non-Insulin-Dependent | NA | BeFree | Detail | |
| 0.001 | Diabetic Nephropathy | Identification of NOD2 as a novel target of RNA-binding protein HuR: evidence fr... | BeFree | 25528059 | Detail |
| <0.001 | diabetic retinopathy | We recently demonstrated that 12/15-lipoxygenase (LOX) derived metabolites, hydr... | BeFree | 25562624 | Detail |
| <0.001 | diabetic retinopathy | A lipidomic screen of hyperglycemia-treated HRECs links 12/15-Lipoxygenase to mi... | BeFree | 25598081 | Detail |
| 0.001 | gastritis | The results suggest that targeting NADPH oxidase may prevent the development of ... | BeFree | 26069142 | Detail |
| <0.001 | gastroesophageal reflux disease | NA | BeFree | Detail | |
| 0.001 | glioblastoma | NA | BeFree | Detail | |
| 0.001 | Glioma | NA | BeFree | Detail | |
| 0.035 | chronic granulomatous disease | Chronic granulomatous disease (CGD), a rare inherited disorder of the innate imm... | BeFree,LHGDN | 24446915 | Detail |
| 0.035 | chronic granulomatous disease | Chronic granulomatous disease (CGD) is an inherited disorder, with phagocytes fa... | BeFree,LHGDN | 24943880 | Detail |
| 0.035 | chronic granulomatous disease | The observation by magnetic resonance imaging and computerized tomography of red... | BeFree,LHGDN | 25239440 | Detail |
| 0.001 | Heart failure | NA | BeFree | Detail | |
| 0.001 | congestive heart failure | NA | BeFree | Detail | |
| <0.001 | Myocardial rupture | NA | BeFree | Detail | |
| <0.001 | Ventricular Septal Defects | NA | BeFree | Detail | |
| <0.001 | HIV Infections | NA | BeFree | Detail | |
| <0.001 | Hypercholesterolemia | NA | BeFree | Detail | |
| 0.001 | hyperglycemia | NA | BeFree | Detail | |
| 0.004 | Hypertensive disease | NADPH oxidases (NOXs) are reactive oxygen species (ROS)-generating enzymes impli... | BeFree | 25066192 | Detail |
| 0.004 | Hypertensive disease | Interestingly, a positive family history of hypertension in black men did not fu... | BeFree | 25527783 | Detail |
| <0.001 | pulmonary hypertension | NA | BeFree | Detail | |
| <0.001 | hypothyroidism | Hypothyroidism-associated missense mutation impairs NADPH oxidase activity and i... | BeFree | 24853759 | Detail |
| <0.001 | Immunologic Deficiency Syndromes | NA | BeFree | Detail | |
| <0.001 | Inflammatory Bowel Diseases | NA | BeFree | Detail | |
| <0.001 | Intestinal Diseases | NA | BeFree | Detail | |
| <0.001 | irritable bowel syndrome | NA | BeFree | Detail | |
| 0.001 | ischemia | In conclusion, our findings suggest that NADPH oxidase is activated during ische... | BeFree | 25017967 | Detail |
| <0.001 | Kidney Failure, Acute | NA | BeFree | Detail | |
| <0.001 | Leukemia, Myelocytic, Acute | NA | BeFree | Detail | |
| <0.001 | Myeloid Leukemia, Chronic | NADPH oxidases as therapeutic targets in chronic myelogenous leukemia. | BeFree | 24833663 | Detail |
| <0.001 | acute promyelocytic leukemia | NA | BeFree | Detail | |
| 0.120 | Lipid Metabolism, Inborn Errors | NA | CTD_human | Detail | |
| <0.001 | Liver Abscess | NA | BeFree | Detail | |
| <0.001 | Liver diseases | NA | BeFree | Detail | |
| <0.001 | Lung diseases | NA | BeFree | Detail | |
| <0.001 | Lupus Erythematosus, Systemic | Systemic lupus erythematosus-associated neutrophil cytosolic factor 2 mutation a... | BeFree | 25795782 | Detail |
| <0.001 | malaria | NA | BeFree | Detail | |
| <0.001 | melanoma | Using the highly metastatic human melanoma cell line MV3, we observed that pharm... | BeFree | 24911159 | Detail |
| <0.001 | Meningitis, Pneumococcal | NA | BeFree | Detail | |
| 0.004 | coronary artery disease | Multivariate logistic regression analysis with adjustment for age, body mass ind... | BeFree | 14709372 | Detail |
| <0.001 | Hypercholesterolemia | Multivariate logistic regression analysis with adjustment for age, body mass ind... | BeFree | 14709372 | Detail |
| <0.001 | hyperuricemia | Multivariate logistic regression analysis with adjustment for age, body mass ind... | BeFree | 14709372 | Detail |
| <0.001 | multiple myeloma | NA | BeFree | Detail | |
| <0.001 | multiple sclerosis | NA | BeFree | Detail | |
| 0.001 | Mycoses | Chronic granulomatous disease (CGD), a rare inherited disorder of the innate imm... | BeFree | 24446915 | Detail |
| <0.001 | Myelodysplasia | NA | BeFree | Detail | |
| 0.001 | myocardial infarction | NA | BeFree | Detail | |
| <0.001 | Nasal Polyps | NA | BeFree | Detail | |
| <0.001 | neuroblastoma | NA | BeFree | Detail | |
| 0.002 | Parkinson disease | NA | GAD | Detail | |
| <0.001 | Periodontitis, Juvenile | NA | BeFree | Detail | |
| <0.001 | Phenylketonurias | In our previous work, we investigated the role of NADPH oxidase (NOX) in a Pahen... | BeFree | 25256805 | Detail |
| <0.001 | pneumonia | NA | BeFree | Detail | |
| <0.001 | Preleukemia | NA | BeFree | Detail | |
| <0.001 | pulmonary fibrosis | NA | BeFree | Detail | |
| <0.001 | Respiratory Tract Infections | NA | BeFree | Detail | |
| <0.001 | Retinal Diseases | NA | BeFree | Detail | |
| <0.001 | systemic scleroderma | A reactive oxygen species-mediated loop maintains increased expression of NADPH ... | BeFree | 25707572 | Detail |
| <0.001 | systemic scleroderma | Intracellular free radical production by peripheral blood T lymphocytes from pat... | BeFree | 25889655 | Detail |
| <0.001 | Seizures | Seizure activity results in calcium- and mitochondria-independent ROS production... | BeFree | 25275601 | Detail |
| <0.001 | Septicemia | Here, we provide mechanistic insights into diminished mRNA stability of the NADP... | BeFree | 24844655 | Detail |
| <0.001 | Sleep Apnea Syndromes | NA | BeFree | Detail | |
| 0.004 | Cerebrovascular accident | NADPH oxidases (NOXs) are reactive oxygen species (ROS)-generating enzymes impli... | BeFree,LHGDN | 25066192 | Detail |
| <0.001 | Tachycardia | NA | BeFree | Detail | |
| 0.002 | Tobacco use disorder | NA | GAD | Detail | |
| <0.001 | Chagas disease | NA | BeFree | Detail | |
| <0.001 | uremia | NA | BeFree | Detail | |
| <0.001 | ureteral obstruction | ATM activation (pATM(Ser1981)) increased 4-fold in the tubulointerstitial region... | BeFree | 25480384 | Detail |
| 0.001 | Vascular Diseases | Endothelial NADPH oxidases: which NOX to target in vascular disease? | BeFree | 25066192 | Detail |
| <0.001 | vitiligo | NA | BeFree | Detail | |
| <0.001 | xeroderma pigmentosum | NA | BeFree | Detail | |
| <0.001 | B-Cell Lymphomas | Association of NADPH oxidase polymorphisms with anthracycline-induced cardiotoxi... | BeFree | 25823784 | Detail |
| <0.001 | motor neuron disease | NA | BeFree | Detail | |
| <0.001 | Peripheral Vascular Diseases | NA | BeFree | Detail | |
| <0.001 | antiphospholipid syndrome | NA | BeFree | Detail | |
| <0.001 | essential hypertension | NA | BeFree | Detail | |
| <0.001 | renal fibrosis | NA | BeFree | Detail | |
| <0.001 | Adenocarcinoma of lung (disorder) | NA | BeFree | Detail | |
| <0.001 | lingual-facial-buccal dyskinesia | NA | BeFree | Detail | |
| <0.001 | Disease of capillaries | NA | BeFree | Detail | |
| <0.001 | Prion Diseases | Here we analyzed the contribution of NOX2, a prominent NADPH oxidase, to prion d... | BeFree | 25502554 | Detail |
| <0.001 | Williams syndrome | NA | BeFree | Detail | |
| <0.001 | Tumor Progression | NA | BeFree | Detail | |
| 0.001 | pancreatic carcinoma | NA | BeFree | Detail | |
| <0.001 | invasive aspergillosis | NA | BeFree | Detail | |
| <0.001 | Fibrosis, Liver | NA | BeFree | Detail | |
| <0.001 | Erectile dysfunction | NA | BeFree | Detail | |
| 0.001 | Malignant neoplasm of lung | NA | BeFree | Detail | |
| <0.001 | Sepsis | Here, we provide mechanistic insights into diminished mRNA stability of the NADP... | BeFree | 24844655 | Detail |
| <0.001 | Ambiguous genitalia | NA | BeFree | Detail | |
| <0.001 | hyperargininemia | NA | BeFree | Detail | |
| <0.001 | Congenital Methemoglobinemia | NA | BeFree | Detail | |
| <0.001 | Rhinovirus infection | NA | BeFree | Detail | |
| <0.001 | Liver and Intrahepatic Biliary Tract Carcinoma | NA | BeFree | Detail | |
| 0.002 | Adenocarcinoma Of Esophagus | NA | BeFree | Detail | |
| <0.001 | Adenocarcinoma of pancreas | NA | BeFree | Detail | |
| <0.001 | Restenosis | NA | BeFree | Detail | |
| <0.001 | Impaired cognition | NA | BeFree | Detail | |
| <0.001 | Congenital neutropenia | NA | BeFree | Detail | |
| <0.001 | Endemic Cretinism | A novel missense mutation (I26M) in DUOXA2 causing congenital goiter hypothyroid... | BeFree | 25675383 | Detail |
| <0.001 | Malignant neoplasm of liver | NA | BeFree | Detail | |
| 0.001 | Malignant neoplasm of pancreas | NA | BeFree | Detail | |
| <0.001 | Congenital goiter | A novel missense mutation (I26M) in DUOXA2 causing congenital goiter hypothyroid... | BeFree | 25675383 | Detail |
| 0.002 | Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site | We found that the ATPases associated with a variety of cellular activities (AAA(... | BeFree | 24834789 | Detail |
| 0.002 | Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site | NADPH oxidase produces a large amount of reactive oxygen species (ROS) in Helico... | BeFree | 26069142 | Detail |
| <0.001 | Malignant neoplasm of prostate | NA | BeFree | Detail | |
| 0.002 | Primary immune deficiency disorder | NA | BeFree | Detail | |
| <0.001 | Leukocyte adhesion deficiency type 1 | NA | BeFree | Detail | |
| <0.001 | Sinus Node Dysfunction (disorder) | NA | BeFree | Detail | |
| <0.001 | Human anaplasmosis due to Anaplasma phagocytophilum | NA | BeFree | Detail | |
| <0.001 | Sleep Apnea, Obstructive | NA | BeFree | Detail | |
| <0.001 | Neurodegenerative Disorders | NA | BeFree | Detail | |
| <0.001 | Hepatitis C, Chronic | NA | BeFree | Detail | |
| <0.001 | Thyroid carcinoma | NA | BeFree | Detail | |
| 0.002 | Cardiovascular Diseases | Some examples include the alanine-to-valine substitution at codon 222 (Ala222--&... | BeFree | 11916749 | Detail |
| <0.001 | Toxic nephropathy | NA | BeFree | Detail | |
| 0.001 | Carcinogenesis | NA | BeFree | Detail | |
| <0.001 | hyperhomocysteinemia | NA | BeFree | Detail | |
| <0.001 | monocytic leukemia | NA | BeFree | Detail | |
| <0.001 | prostate carcinoma | NA | BeFree | Detail | |
| <0.001 | Epithelial ovarian cancer | NA | BeFree | Detail | |
| 0.001 | breast carcinoma | NA | BeFree | Detail | |
| 0.001 | Carcinoma of lung | NA | BeFree | Detail | |
| <0.001 | Tardive Dyskinesia | NA | BeFree | Detail | |
| <0.001 | colon carcinoma | NA | BeFree | Detail | |
| <0.001 | Central neuroblastoma | NA | BeFree | Detail | |
| <0.001 | Middle Cerebral Artery Occlusion | NA | BeFree | Detail | |
| <0.001 | hyperuricemia | NA | BeFree | Detail | |
| <0.001 | Acute Cerebrovascular Accidents | NA | BeFree | Detail | |
| <0.001 | Helicobacter pylori infection | The results suggest that targeting NADPH oxidase may prevent the development of ... | BeFree | 26069142 | Detail |
| 0.002 | Endothelial dysfunction | NA | BeFree | Detail | |
| <0.001 | Infection pyogenic | NA | BeFree | Detail | |
| <0.001 | Infectious disease of lung | NA | BeFree | Detail | |
| <0.001 | Cerebral Ischemia | NA | BeFree | Detail | |
| <0.001 | ovarian neoplasm | NA | BeFree | Detail | |
| <0.001 | Renal ischaemia | Complement-dependent NADPH oxidase enzyme activation in renal ischemia/reperfusi... | BeFree | 25017967 | Detail |
| 0.001 | Deficiency of oxidase | NA | BeFree | Detail | |
| <0.001 | M5b Acute differentiated monocytic leukemia | NA | BeFree | Detail | |
| <0.001 | Classical Hodgkin's Lymphoma | NA | BeFree | Detail | |
| <0.001 | pancreatic ductal adenocarcinoma | NA | BeFree | Detail | |
| <0.001 | Cardiac fibrosis | NA | BeFree | Detail | |
| <0.001 | Myocardial necrosis | NA | BeFree | Detail | |
| <0.001 | Mammary Neoplasms | NA | BeFree | Detail | |
| <0.001 | Mammary Tumorigenesis | NA | BeFree | Detail | |
| <0.001 | Cancer Cell Growth | NA | BeFree | Detail | |
| <0.001 | Chronic Kidney Diseases | Apoptosis was also increased due to NADPH oxidase gp91 activation and mitochondr... | BeFree | 25030617 | Detail |
| <0.001 | Glioblastoma multiforme | NA | BeFree | Detail | |
| <0.001 | Peripheral Arterial Diseases | NA | BeFree | Detail | |
| <0.001 | Idiopathic Pulmonary Fibrosis | NA | BeFree | Detail | |
| <0.001 | Recurrent infections (sinusitis and bacterial pneumonia and meningitis) | NA | BeFree | Detail | |
| <0.001 | VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding) | NA | BeFree | Detail | |
| <0.001 | severe congenital neutropenia | NA | BeFree | Detail | |
| 0.120 | 2,4-Dienoyl-CoA Reductase Deficiency | NA | CTD_human | Detail | |
| 0.004 | coronary artery disease | NA | BeFree | Detail | |
| <0.001 | Urothelial Carcinoma | NA | BeFree | Detail | |
| <0.001 | liver carcinoma | NA | BeFree | Detail | |
| <0.001 | Nasopharyngeal carcinoma | NA | BeFree | Detail | |
| <0.001 | Antley-Bixler Syndrome, Autosomal Dominant | NA | BeFree | Detail | |
| <0.001 | Deficiency of glucose-6-phosphate dehydrogenase | NA | BeFree | Detail | |
| <0.001 | Nonalcoholic Steatohepatitis | Micro-RNA 21 inhibition of SMAD7 enhances fibrogenesis via leptin-mediated NADPH... | BeFree | 25501551 | Detail |
| <0.001 | Homocysteinemia | NA | BeFree | Detail | |
| <0.001 | Autosomal Recessive Chronic Granulomatous Disease | NA | BeFree | Detail | |
| <0.001 | Hemoglobin M Disease | NA | BeFree | Detail | |
| <0.001 | Abscess | NA | BeFree | Detail | |
| <0.001 | adenocarcinoma | NA | BeFree | Detail | |
| <0.001 | agranulocytosis | NA | BeFree | Detail | |
| 0.002 | Albuminuria | NA | GAD | Detail | |
| <0.001 | Alzheimer's disease | NA | BeFree | Detail | |
| 0.001 | amyotrophic lateral sclerosis | NA | BeFree | Detail | |
| <0.001 | Anemia, Sickle Cell | NA | BeFree | Detail | |
| 0.004 | arteriosclerosis | The observation by magnetic resonance imaging and computerized tomography of red... | BeFree | 25239440 | Detail |
| <0.001 | arthritis | NA | BeFree | Detail | |
| <0.001 | rheumatoid arthritis | NA | BeFree | Detail | |
| <0.001 | asthma | NA | BeFree | Detail | |
| <0.001 | Astrocytoma | NA | BeFree | Detail | |
| 0.004 | atherosclerosis | The observation by magnetic resonance imaging and computerized tomography of red... | BeFree | 25239440 | Detail |
| <0.001 | Barrett esophagus | NA | BeFree | Detail | |
| 0.001 | Malignant neoplasm of breast | NA | BeFree | Detail | |
| <0.001 | candidiasis | NA | BeFree | Detail | |
| <0.001 | Malignant tumor of colon | NA | BeFree | Detail |
Annotation
Annotations
| Descrption | Source | Links |
|---|---|---|
| NA | DisGeNET | Detail |
| Additional high-resolution studies in multiple vascular beds are required to address the therapeutic... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The observation by magnetic resonance imaging and computerized tomography of reduced carotid but not... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| A novel missense mutation (I26M) in DUOXA2 causing congenital goiter hypothyroidism impairs NADPH ox... | DisGeNET | Detail |
| Adherent-invasive E. coli LF82 induced ROS production by intestinal NADPH oxidase and altered mucin ... | DisGeNET | Detail |
| Reactive oxygen species (ROS) contribute to the pathogenesis of fibrosis in systemic sclerosis (SSc;... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Identification of NOD2 as a novel target of RNA-binding protein HuR: evidence from NADPH oxidase-med... | DisGeNET | Detail |
| We recently demonstrated that 12/15-lipoxygenase (LOX) derived metabolites, hydroxyeicosatetraenoic ... | DisGeNET | Detail |
| A lipidomic screen of hyperglycemia-treated HRECs links 12/15-Lipoxygenase to microvascular dysfunct... | DisGeNET | Detail |
| The results suggest that targeting NADPH oxidase may prevent the development of gastric inflammation... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Chronic granulomatous disease (CGD), a rare inherited disorder of the innate immune system, results ... | DisGeNET | Detail |
| Chronic granulomatous disease (CGD) is an inherited disorder, with phagocytes failing to produce ant... | DisGeNET | Detail |
| The observation by magnetic resonance imaging and computerized tomography of reduced carotid but not... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NADPH oxidases (NOXs) are reactive oxygen species (ROS)-generating enzymes implicated in the pathoph... | DisGeNET | Detail |
| Interestingly, a positive family history of hypertension in black men did not further enhance PBMC-d... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Hypothyroidism-associated missense mutation impairs NADPH oxidase activity and intracellular traffic... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| In conclusion, our findings suggest that NADPH oxidase is activated during ischemia/reperfusion in a... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NADPH oxidases as therapeutic targets in chronic myelogenous leukemia. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Systemic lupus erythematosus-associated neutrophil cytosolic factor 2 mutation affects the structure... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Using the highly metastatic human melanoma cell line MV3, we observed that pharmacological NADPH oxi... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Multivariate logistic regression analysis with adjustment for age, body mass index, and the prevalen... | DisGeNET | Detail |
| Multivariate logistic regression analysis with adjustment for age, body mass index, and the prevalen... | DisGeNET | Detail |
| Multivariate logistic regression analysis with adjustment for age, body mass index, and the prevalen... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Chronic granulomatous disease (CGD), a rare inherited disorder of the innate immune system, results ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| In our previous work, we investigated the role of NADPH oxidase (NOX) in a Pahenu2-BTBR PKU mouse mo... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| A reactive oxygen species-mediated loop maintains increased expression of NADPH oxidases 2 and 4 in ... | DisGeNET | Detail |
| Intracellular free radical production by peripheral blood T lymphocytes from patients with systemic ... | DisGeNET | Detail |
| Seizure activity results in calcium- and mitochondria-independent ROS production via NADPH and xanth... | DisGeNET | Detail |
| Here, we provide mechanistic insights into diminished mRNA stability of the NADPH oxidase Nox2 on ma... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NADPH oxidases (NOXs) are reactive oxygen species (ROS)-generating enzymes implicated in the pathoph... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| ATM activation (pATM(Ser1981)) increased 4-fold in the tubulointerstitial region of the unilateral u... | DisGeNET | Detail |
| Endothelial NADPH oxidases: which NOX to target in vascular disease? | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Association of NADPH oxidase polymorphisms with anthracycline-induced cardiotoxicity in the RICOVER-... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Here we analyzed the contribution of NOX2, a prominent NADPH oxidase, to prion diseases. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Here, we provide mechanistic insights into diminished mRNA stability of the NADPH oxidase Nox2 on ma... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| A novel missense mutation (I26M) in DUOXA2 causing congenital goiter hypothyroidism impairs NADPH ox... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| A novel missense mutation (I26M) in DUOXA2 causing congenital goiter hypothyroidism impairs NADPH ox... | DisGeNET | Detail |
| We found that the ATPases associated with a variety of cellular activities (AAA(+) ) module of HpLon... | DisGeNET | Detail |
| NADPH oxidase produces a large amount of reactive oxygen species (ROS) in Helicobacter pylori (H. py... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Some examples include the alanine-to-valine substitution at codon 222 (Ala222-->Val) [DNA: C-to-T... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The results suggest that targeting NADPH oxidase may prevent the development of gastric inflammation... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Complement-dependent NADPH oxidase enzyme activation in renal ischemia/reperfusion injury. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Apoptosis was also increased due to NADPH oxidase gp91 activation and mitochondrial Bax translocatio... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Micro-RNA 21 inhibition of SMAD7 enhances fibrogenesis via leptin-mediated NADPH oxidase in experime... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The observation by magnetic resonance imaging and computerized tomography of reduced carotid but not... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The observation by magnetic resonance imaging and computerized tomography of reduced carotid but not... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
Overlapped Transcript Coordinates
| Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
|---|
Overlapped Transcript
| Gene | Transcript ID | Chromosome | Start | Stop | Links |
|---|
- Gene
- -
- dbSNP
- rs16874954 dbSNP
- Genome
- hg19
- Position
- chr8:91,013,705-91,065,861
- Variant Type
- snv
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