Annotation Detail
Information
- Associated Genes
- DECR1
- Associated Variants
-
DECR1 MUTATION
DECR1 MUTATION - Associated Disease
- Sepsis
- Source Database
- DisGeNET
- Description
- Here, we provide mechanistic insights into diminished mRNA stability of the NADPH oxidase Nox2 on macrophage M2 polarization and therefore reduced ROS formation in sepsis.
- Pubmed
- 24844655
- Section of the abstract supporting the evidence
- AIMS
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 4
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
Drugs