chr12:7033626:> Detail (hg19)

Information

Genome

Assembly Position
hg19 chr12:7,033,626-7,051,484
hg38 chr12:6,924,463-6,942,321 

HGVS

Type Transcript Protein
Summary

MGeND

Clinical significance
Variant entry
GWAS entry
Disease area statistics Show details

Frequency

[No Data.]

Prediction

[No Data.]

ClinVar

Clinical Significance
Review star [No Data.]
Show details
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
Score Disease name Description Source Pubmed Links
<0.001 squamous cell carcinoma NA BeFree Detail
<0.001 Cardiomyopathy, Dilated NA BeFree Detail
0.002 myoclonic cerebellar dyssynergia NA GAD Detail
<0.001 Malignant tumor of cervix NA BeFree Detail
0.001 Primary biliary cirrhosis Here, the authors discuss the current findings on two spontaneous (nonobese diab... BeFree 25057952 Detail
<0.001 cholera NA BeFree Detail
<0.001 cholesteatoma NOD-Like Receptor Signaling in Cholesteatoma. BeFree 25922834 Detail
<0.001 Chondritis NA BeFree Detail
<0.001 chordoma NA BeFree Detail
<0.001 colitis NA BeFree Detail
<0.001 ulcerative colitis NA BeFree Detail
<0.001 colorectal carcinoma NA BeFree Detail
<0.001 Colorectal Neoplasms NA BeFree Detail
<0.001 Crohn Disease NA BeFree Detail
<0.001 Dengue Fever NA BeFree Detail
<0.001 Mental Depression NA BeFree Detail
<0.001 depressive disorder NA BeFree Detail
<0.001 dermatitis herpetiformis NA BeFree Detail
<0.001 Dermatitis, Atopic NA BeFree Detail
0.021 Diabetes Endogenous miR-29b, spontaneously released from beta-cells within exosomes, stim... BeFree 25203514 Detail
0.021 Diabetes While numerous antigen-specific therapies prevent diabetes in NOD mice, successf... BeFree 25302633 Detail
0.021 Diabetes In the resulting 3A9 TCR:iHEL NOD.H2(k)-Chr12 mice, we observed a significant de... BeFree 25623266 Detail
0.021 Diabetes Similar effects were seen in the NOD mouse model, and in these mice, 1 week of t... BeFree 26368307 Detail
0.021 diabetes mellitus Endogenous miR-29b, spontaneously released from beta-cells within exosomes, stim... BeFree 25203514 Detail
0.021 diabetes mellitus While numerous antigen-specific therapies prevent diabetes in NOD mice, successf... BeFree 25302633 Detail
0.021 diabetes mellitus In the resulting 3A9 TCR:iHEL NOD.H2(k)-Chr12 mice, we observed a significant de... BeFree 25623266 Detail
0.021 diabetes mellitus Similar effects were seen in the NOD mouse model, and in these mice, 1 week of t... BeFree 26368307 Detail
0.017 Diabetes Mellitus, Insulin-Dependent Herein, we have tested the therapeutic potential of a soluble HLA-DR4-GAD65 271-... BeFree 24335553 Detail
0.017 Diabetes Mellitus, Insulin-Dependent The cells engrafted in HLA-A2-transgenic NOD-scid IL2rγ(null) mice and could be ... BeFree 25302633 Detail
0.017 Diabetes Mellitus, Insulin-Dependent Type 1 diabetes onset has been convincingly linked to infection by numerous ente... BeFree 25430610 Detail
0.017 Diabetes Mellitus, Insulin-Dependent Identification of autoreactive CD8+ T cell responses targeting chromogranin A in... BeFree 25958206 Detail
<0.001 Diabetes Mellitus, Non-Insulin-Dependent NA BeFree Detail
<0.001 diphtheria NA BeFree Detail
<0.001 Down syndrome NA BeFree Detail
<0.001 Shigella Infections NOD-like receptor signaling pathway and shigellosis related pathway were the mos... BeFree 24867262 Detail
<0.001 Eczema NA BeFree Detail
<0.001 encephalitis NA BeFree Detail
0.001 Gall Bladder Diseases Here, the authors discuss the current findings on two spontaneous (nonobese diab... BeFree 25057952 Detail
<0.001 gastritis NA BeFree Detail
<0.001 glioblastoma Treatment of GBM xenografts in NOD/SCID mice with NK cells from a KIR2DS2(+) don... BeFree 25381437 Detail
<0.001 Glioma NA BeFree Detail
<0.001 glomerulonephritis NA BeFree Detail
<0.001 gonorrhea We examined the ability of NOD1 and NOD2 to recognize Neisseria gonorrhoeae, and... BeFree 23884094 Detail
0.002 Graft-vs-Host Disease NOD/LtSz-scidIL2rg(-/-) (NSG) mice were used for our xenogeneic mouse model of G... BeFree 25596424 Detail
0.002 Graft-vs-Host Disease The therapeutic efficacy of HuMoSCs was evaluated by using a graft-versus-host d... BeFree 25630940 Detail
0.002 Graft-vs-Host Disease Sublethally irradiated NOD/Shi-scidIL2rγ(null) mice transplanted with human umbi... BeFree 25786689 Detail
<0.001 chronic granulomatous disease NA BeFree Detail
0.001 cardiac arrest However, at least half of dominant ataxias (SCAs) are caused by (CAG)n repeat ex... BeFree 25192506 Detail
<0.001 hepatitis C NA BeFree Detail
<0.001 Herpes Simplex Infections NA BeFree Detail
0.003 HIV Infections Immunodeficient NOD SCID IL-2R(-/-) mice were immunologically reconstituted by a... BeFree 24593860 Detail
<0.001 Hodgkin Disease NA BeFree Detail
0.005 Huntington disease NA BeFree,GAD Detail
<0.001 Hydatidiform mole Mutations in NLRP7 (NOD-like-receptor family, pyrin domain containing 7) are res... BeFree 25082979 Detail
0.002 hyperglycemia Here we show that Deaf1-Var1 expression correlates with the severity of disease ... BeFree 25187368 Detail
0.012 Immunologic Deficiency Syndromes Immunodeficient NOD SCID IL-2R(-/-) mice were immunologically reconstituted by a... BeFree 24593860 Detail
0.012 Immunologic Deficiency Syndromes Notably, CD24+ cells produce tumors following inoculation of as few as 500 cells... BeFree 24955581 Detail
0.012 Immunologic Deficiency Syndromes These findings were also observed in immunodeficient NOD/SCID mice treated with ... BeFree 25133686 Detail
0.012 Immunologic Deficiency Syndromes We generated a severe immunodeficient NOD/Shi-scid-IL-2Rγ(null) (NOG) mouse subs... BeFree 25712215 Detail
0.012 Immunologic Deficiency Syndromes Human CD34(+) human cord blood cells were transduced with an FV vector encoding ... BeFree 25786870 Detail
<0.001 Inflammatory Bowel Diseases NA BeFree Detail
<0.001 influenza Expression of members of the NOD domain-like receptor family of inflammasome gen... BeFree 24652041 Detail
<0.001 Intestinal Diseases NA BeFree Detail
<0.001 Krukenberg Tumor NA BeFree Detail
<0.001 Fibroid Tumor NA BeFree Detail
0.005 leukemia Importantly, DLL4 blockade impaired growth of T-ALL cells in NOD/SCID mice and i... BeFree 25355291 Detail
0.005 leukemia We previously described that rapid engraftment of patient ALL cells transplanted... BeFree 25682198 Detail
0.005 leukemia Notably, C1 administration impaired the regeneration of leukemia in secondary se... BeFree 26224647 Detail
0.001 chronic lymphocytic leukemia Inhibition of IL-6 signaling with antibodies or small-molecule Janus kinase inhi... BeFree 26041742 Detail
<0.001 lymphoid leukemia Attenuated measles virus controls pediatric acute B-lineage lymphoblastic leukem... BeFree 24700491 Detail
0.002 Acute lymphocytic leukemia Attenuated measles virus controls pediatric acute B-lineage lymphoblastic leukem... BeFree 24700491 Detail
<0.001 Leukemia, Lymphocytic, Acute, L1 NA BeFree Detail
0.005 Leukemia, Myelocytic, Acute Although the in vivo NOD-SCID or NSG xenotransplantation model is currently stil... BeFree 25062630 Detail
<0.001 myeloid leukemia NA BeFree Detail
0.001 Myeloid Leukemia, Chronic The administration of actinomycin D, an inhibitor of de novo mRNA synthesis, pre... BeFree 25133686 Detail
<0.001 Precursor B-Cell Lymphoblastic Leukemia-Lymphoma NA BeFree Detail
<0.001 Leukemia, T-Cell NA BeFree Detail
0.001 Adult T-Cell Lymphoma/Leukemia NA BeFree Detail
<0.001 leukodystrophy NA BeFree Detail
<0.001 Lupus Erythematosus, Systemic NA BeFree Detail
0.001 lymphoma NA BeFree Detail
<0.001 lymphopenia GIMAP5 has a key role in BB-DR rat and NOD mouse lymphopenia. BeFree 25964488 Detail
<0.001 Lymphoproliferative Disorders NA BeFree Detail
0.003 Machado-Joseph disease NA BeFree,LHGDN Detail
<0.001 malaria NA BeFree Detail
<0.001 Malignant neoplasm of stomach The NOD-like receptor signalling pathway in Helicobacter pylori infection and re... BeFree 24901306 Detail
<0.001 melanoma NA BeFree Detail
<0.001 meningococcal meningitis NA BeFree Detail
<0.001 Meningitis, Pneumococcal NA BeFree Detail
<0.001 Metabolic Diseases NA BeFree Detail
0.003 multiple myeloma NA BeFree Detail
<0.001 Mycoses NA BeFree Detail
<0.001 myelofibrosis We demonstrated that both splenic and peripheral blood (PB) MF CD34(+) cells equ... BeFree 25461253 Detail
<0.001 myocarditis NA BeFree Detail
<0.001 myositis NA BeFree Detail
0.002 Myotonic dystrophy NA GAD Detail
0.004 Neoplasm Metastasis In vitro and in vivo assays were carried out to evaluate the effects of NRP1 on ... BeFree 25231404 Detail
0.004 Neoplasm Metastasis In vivo studies with xenotransplant models in NOD-scid mice showed that OPN expr... BeFree 25531323 Detail
0.004 Neoplasm Metastasis NOD/SCID gamma mouse xenografts demonstrated tumor formation and metastasis. BeFree 25644184 Detail
<0.001 nephroblastoma NA BeFree Detail
<0.001 neurilemmoma NA BeFree Detail
<0.001 neuroblastoma NA BeFree Detail
<0.001 Neurofibromatosis 2 NA BeFree Detail
0.002 obesity Transcriptome analysis of human adipocytes implicates the NOD-like receptor path... BeFree 25011057 Detail
0.002 obesity Nucleotide-binding oligomerization domain (NOD) protein, as cytoplasmic receptor... BeFree 26052894 Detail
<0.001 oligodendroglioma NA BeFree Detail
<0.001 otitis media Expression of members of the NOD domain-like receptor family of inflammasome gen... BeFree 24652041 Detail
<0.001 ovarian carcinoma NOD/SCID nude mice experiments showed that ovarian cancer stem cell tumorigenici... BeFree 25491627 Detail
<0.001 Pancreatic Neoplasm In vivo treatment of orthotopic pancreatic tumors in NOD/SCID mice with GSI bloc... BeFree 24647545 Detail
<0.001 papilloma A biopsy of fresh tracheal papilloma was xenografted into a NOD-scid-IL2Rgamma(n... BeFree 25124839 Detail
<0.001 Pelvic Pain NA BeFree Detail
<0.001 Polychondritis, Relapsing NA BeFree Detail
<0.001 polycystic ovary syndrome Among these genes, we identified that several significant pathways, including th... BeFree 25051372 Detail
<0.001 polycythemia vera NA BeFree Detail
<0.001 Precancerous Conditions NA BeFree Detail
<0.001 Preleukemia NA BeFree Detail
<0.001 Prostatic Neoplasms NA BeFree Detail
<0.001 pulmonary edema NA BeFree Detail
<0.001 Rheumatism NA BeFree Detail
<0.001 Salivary Gland Diseases NA BeFree Detail
0.005 schizophrenia NA BeFree,GAD Detail
<0.001 sialadenitis NA BeFree Detail
<0.001 Spastic paraplegia NA BeFree Detail
<0.001 synovial sarcoma NA BeFree Detail
0.001 teratoma NA BeFree Detail
0.002 thyroiditis NA BeFree Detail
<0.001 Uterine Fibroids NA BeFree Detail
<0.001 vasculitis NOD-like receptor signaling pathway and shigellosis related pathway were the mos... BeFree 24867262 Detail
<0.001 Xerostomia NA BeFree Detail
<0.001 B-Cell Lymphomas NA BeFree Detail
0.051 severe combined immunodeficiency Immunodeficient NOD SCID IL-2R(-/-) mice were immunologically reconstituted by a... BeFree 24593860 Detail
0.051 severe combined immunodeficiency Additionally, in vivo studies showed that wogonin decreased the number of CML ce... BeFree 25149543 Detail
0.051 severe combined immunodeficiency TG20 cells possess all of the characteristic features of GSCs: the expression of... BeFree 25175359 Detail
0.051 severe combined immunodeficiency In vivo, DLL4 is expressed in the spleen and the bone marrow (BM) of NOD/SCID mi... BeFree 25355291 Detail
0.051 severe combined immunodeficiency NOD/SCID nude mice experiments showed that ovarian cancer stem cell tumorigenici... BeFree 25491627 Detail
0.051 severe combined immunodeficiency The human U87MG GBM cell line or patient-derived early passage GBM cells were ad... BeFree 25501993 Detail
0.051 severe combined immunodeficiency The therapeutic efficacy of HuMoSCs was evaluated by using a graft-versus-host d... BeFree 25630940 Detail
0.051 severe combined immunodeficiency NOD/SCID gamma mice produced useful patient-derived xenografts for orthotopic or... BeFree 25644184 Detail
0.051 severe combined immunodeficiency Orthotopic xenografts of human CM were established by subconjunctival injection ... BeFree 25722211 Detail
0.051 severe combined immunodeficiency Modified cells maintained their ability to engraft NOD/SCID/IL2rγ(null) mice and... BeFree 25733580 Detail
0.051 severe combined immunodeficiency Human CD34(+) human cord blood cells were transduced with an FV vector encoding ... BeFree 25786870 Detail
0.051 severe combined immunodeficiency NOD/SCID gamma mice bearing CEM or Molt4 xenografts were treated with 6-TG and P... BeFree 25917288 Detail
<0.001 Mucopolysaccharidosis VII NA BeFree Detail
<0.001 acute leukemia NA BeFree Detail
0.016 Ataxia, Spinocerebellar NA BeFree,GAD,LHGDN Detail
<0.001 Epstein-Barr Virus Infections NA BeFree Detail
<0.001 Complete atrioventricular block NA BeFree Detail
0.001 Secondary malignant neoplasm of lung NA BeFree Detail
<0.001 dacryoadenitis NA BeFree Detail
<0.001 adrenoleukodystrophy NA BeFree Detail
<0.001 Polyarthritis NA BeFree Detail
<0.001 Leukemic Infiltration NA BeFree Detail
0.006 Diabetes, Autoimmune NA BeFree Detail
<0.001 pediatric acute myeloblastic leukemia NA BeFree Detail
<0.001 uveal melanoma NA BeFree Detail
<0.001 Memory impairment NA BeFree Detail
<0.001 Cerebral atrophy NA BeFree Detail
<0.001 pancreatic carcinoma The study suggested CEBPD, FOSB, SFN, KLF5, PTX3, NR4A3, IL-6, and NOD-like rece... BeFree 25409614 Detail
<0.001 Gastrointestinal Stromal Tumors NA BeFree Detail
<0.001 Malignant neoplasm of lung Here we evaluated the enhanced efficacy of cationic liposome-mediated delivery o... BeFree 24410728 Detail
<0.001 Spastic syndrome NA BeFree Detail
<0.001 Impaired glucose tolerance NA BeFree Detail
<0.001 Liver and Intrahepatic Biliary Tract Carcinoma NA BeFree Detail
<0.001 Solid tumour NA BeFree Detail
<0.001 cervix carcinoma NA BeFree Detail
0.003 Atrophic NA LHGDN Detail
<0.001 anaplastic oligodendroglioma NA BeFree Detail
<0.001 Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse NA BeFree Detail
<0.001 Malignant neoplasm of liver NA BeFree Detail
<0.001 Malignant neoplasm of pancreas The study suggested CEBPD, FOSB, SFN, KLF5, PTX3, NR4A3, IL-6, and NOD-like rece... BeFree 25409614 Detail
<0.001 juvenile myelomonocytic leukemia NA BeFree Detail
0.001 prediabetes syndrome Some 75% of pre-diabetic NOD/DR4/B7 dTg mice treated with hu DEF-GAD65 chimera r... BeFree 24335553 Detail
<0.001 Malignant neoplasm of prostate NA BeFree Detail
<0.001 Hematopoietic Neoplasms NA BeFree Detail
0.003 Pallidoluysian degeneration NA BeFree Detail
<0.001 Non-alcoholic Fatty Liver Disease NA BeFree Detail
<0.001 Chronic pelvic pain of female NA BeFree Detail
<0.001 Chronic Infantile Neurological, Cutaneous, and Articular Syndrome Activating-mutations in NOD-like receptor (NLR) family, pyrin domain-containing ... BeFree 25477279 Detail
<0.001 endometrial carcinoma NA BeFree Detail
<0.001 Secondary malignant neoplasm of liver NA BeFree Detail
<0.001 Chlamydia trachomatis infection NA BeFree Detail
<0.001 Neurodegenerative Disorders NA BeFree Detail
0.001 Carcinogenesis NA BeFree Detail
<0.001 prostate carcinoma NA BeFree Detail
<0.001 Hashimoto Disease NA BeFree Detail
0.001 breast carcinoma NA BeFree Detail
<0.001 Terminal illness NA BeFree Detail
<0.001 Carcinoma of lung Here we evaluated the enhanced efficacy of cationic liposome-mediated delivery o... BeFree 24410728 Detail
<0.001 colon carcinoma Immunodeficient NOD SCID IL-2R(-/-) mice were immunologically reconstituted by a... BeFree 24593860 Detail
<0.001 stomach carcinoma The NOD-like receptor signalling pathway in Helicobacter pylori infection and re... BeFree 24901306 Detail
<0.001 Carcinoma of bladder NA BeFree Detail
<0.001 Central neuroblastoma NA BeFree Detail
<0.001 Polychondritis NA BeFree Detail
<0.001 Well Differentiated Oligodendroglioma NA BeFree Detail
0.120 Myoclonic Epilepsies, Progressive NA CTD_human Detail
<0.001 Atrophy, Muscular, Spinobulbar NA BeFree Detail
<0.001 malignant pleural mesothelioma The antitumor activity was displayed when orally administered to MPM-bearing NOD... BeFree 25952930 Detail
<0.001 Helicobacter pylori infection The NOD-like receptor signalling pathway in Helicobacter pylori infection and re... BeFree 24901306 Detail
<0.001 Pelvic pain female NA BeFree Detail
<0.001 Endothelial dysfunction Endoplasmic reticulum stress (ER stress)-associated thioredoxin-interacting prot... BeFree 25446924 Detail
<0.001 Philadelphia chromosome positive NA BeFree Detail
<0.001 Retinoic acid syndrome NA BeFree Detail
<0.001 Stromal Neoplasm NA BeFree Detail
<0.001 ovarian neoplasm NA BeFree Detail
0.002 Genomic Instability NA GAD Detail
<0.001 autoimmune thyroiditis NA BeFree Detail
<0.001 Primary infection NOS NA BeFree Detail
<0.001 Malignant neoplasm of ovary NOD/SCID nude mice experiments showed that ovarian cancer stem cell tumorigenici... BeFree 25491627 Detail
<0.001 Congenital long QT syndrome NA BeFree Detail
<0.001 Brugada Syndrome (disorder) NA BeFree Detail
<0.001 Squamous cell carcinoma of the head and neck NA BeFree Detail
<0.001 Lymphocytic infiltration NA BeFree Detail
<0.001 Persistent infection NA BeFree Detail
<0.001 X-Linked Combined Immunodeficiency Diseases NA BeFree Detail
<0.001 Inflammatory disorder Among these genes, we identified that several significant pathways, including th... BeFree 25051372 Detail
<0.001 Chronic inflammatory disorder The role of intracellular innate immune receptors, the NOD-like receptors, and t... BeFree 25922834 Detail
0.001 Precursor B-cell lymphoblastic leukemia NA BeFree Detail
<0.001 Central nervous system leukaemia NA BeFree Detail
<0.001 pancreatic ductal adenocarcinoma NOD-scid-IL2Rγ(null) mice were subcutaneously implanted with PDAC or PDAC(CBL-lo... BeFree 25348515 Detail
<0.001 Cardiomyopathy, Familial Idiopathic NA BeFree Detail
<0.001 Mammary Neoplasms NA BeFree Detail
0.002 Xenograft Model NA BeFree Detail
<0.001 colorectal cancer NA BeFree Detail
<0.001 Bulbo-Spinal Atrophy, X-Linked NA BeFree Detail
<0.001 uterine corpus cancer NA BeFree Detail
<0.001 Precursor T-Cell Lymphoblastic Leukemia-Lymphoma In vivo, DLL4 is expressed in the spleen and the bone marrow (BM) of NOD/SCID mi... BeFree 25355291 Detail
0.002 Precursor Cell Lymphoblastic Leukemia Lymphoma Attenuated measles virus controls pediatric acute B-lineage lymphoblastic leukem... BeFree 24700491 Detail
0.001 liver carcinoma NA BeFree Detail
<0.001 Cryopyrin-Associated Periodic Syndromes NA BeFree Detail
<0.001 Infectious Otitis Media Expression of members of the NOD domain-like receptor family of inflammasome gen... BeFree 24652041 Detail
<0.001 Hereditary Neurodegenerative Disorder NA BeFree Detail
0.001 Biliary System Disorder Here, the authors discuss the current findings on two spontaneous (nonobese diab... BeFree 25057952 Detail
<0.001 myelodysplastic syndrome NA BeFree Detail
<0.001 Hydatidiform mole, recurrent, 1 Mutations in NLRP7 (NOD-like-receptor family, pyrin domain containing 7) are res... BeFree 25082979 Detail
<0.001 Allergic disposition NA BeFree Detail
<0.001 Secondary malignant neoplasm of ovary NA BeFree Detail
<0.001 Primary myelofibrosis We demonstrated that both splenic and peripheral blood (PB) MF CD34(+) cells equ... BeFree 25461253 Detail
<0.001 Anemia, Hemolytic NA BeFree Detail
<0.001 Anemia, Sickle Cell NA BeFree Detail
<0.001 antisocial personality disorder NA BeFree Detail
<0.001 arteriosclerosis Endothelial dysfunction: the role of sterol regulatory element-binding protein-i... BeFree 25188917 Detail
<0.001 rheumatoid arthritis NA BeFree Detail
0.001 Ataxia However, at least half of dominant ataxias (SCAs) are caused by (CAG)n repeat ex... BeFree 25192506 Detail
<0.001 atherosclerosis Endothelial dysfunction: the role of sterol regulatory element-binding protein-i... BeFree 25188917 Detail
0.002 Autoimmune Diseases The cells engrafted in HLA-A2-transgenic NOD-scid IL2rγ(null) mice and could be ... BeFree 25302633 Detail
<0.001 Bacterial Infections NA BeFree Detail
<0.001 Malignant neoplasm of urinary bladder NA BeFree Detail
<0.001 Blast Phase NA BeFree Detail
<0.001 Bone Diseases NA BeFree Detail
0.001 Malignant neoplasm of breast NA BeFree Detail
<0.001 Malignant tumor of colon Immunodeficient NOD SCID IL-2R(-/-) mice were immunologically reconstituted by a... BeFree 24593860 Detail
<0.001 Malignant neoplasm of endometrium NA BeFree Detail
<0.001 Non-small cell lung carcinoma Surgically resected early-stage non-small-cell lung carcinoma (NSCLC) tumors wer... BeFree 26124487 Detail
Annotation

Annotations

DescrptionSourceLinks
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Here, the authors discuss the current findings on two spontaneous (nonobese diabetic autoimmune bili... DisGeNET Detail
NA DisGeNET Detail
NOD-Like Receptor Signaling in Cholesteatoma. DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Endogenous miR-29b, spontaneously released from beta-cells within exosomes, stimulates TNFa secretio... DisGeNET Detail
While numerous antigen-specific therapies prevent diabetes in NOD mice, successful translation of ro... DisGeNET Detail
In the resulting 3A9 TCR:iHEL NOD.H2(k)-Chr12 mice, we observed a significant decrease in diabetes i... DisGeNET Detail
Similar effects were seen in the NOD mouse model, and in these mice, 1 week of treatment was suffici... DisGeNET Detail
Endogenous miR-29b, spontaneously released from beta-cells within exosomes, stimulates TNFa secretio... DisGeNET Detail
While numerous antigen-specific therapies prevent diabetes in NOD mice, successful translation of ro... DisGeNET Detail
In the resulting 3A9 TCR:iHEL NOD.H2(k)-Chr12 mice, we observed a significant decrease in diabetes i... DisGeNET Detail
Similar effects were seen in the NOD mouse model, and in these mice, 1 week of treatment was suffici... DisGeNET Detail
Herein, we have tested the therapeutic potential of a soluble HLA-DR4-GAD65 271-280 (hu DEF-GAD65) c... DisGeNET Detail
The cells engrafted in HLA-A2-transgenic NOD-scid IL2rγ(null) mice and could be detected in the bloo... DisGeNET Detail
Type 1 diabetes onset has been convincingly linked to infection by numerous enteroviruses including ... DisGeNET Detail
Identification of autoreactive CD8+ T cell responses targeting chromogranin A in humanized NOD mice ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NOD-like receptor signaling pathway and shigellosis related pathway were the most significant latent... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Here, the authors discuss the current findings on two spontaneous (nonobese diabetic autoimmune bili... DisGeNET Detail
NA DisGeNET Detail
Treatment of GBM xenografts in NOD/SCID mice with NK cells from a KIR2DS2(+) donor lacking inhibitor... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
We examined the ability of NOD1 and NOD2 to recognize Neisseria gonorrhoeae, and determined the role... DisGeNET Detail
NOD/LtSz-scidIL2rg(-/-) (NSG) mice were used for our xenogeneic mouse model of GVHD. DisGeNET Detail
The therapeutic efficacy of HuMoSCs was evaluated by using a graft-versus-host disease (GvHD) model ... DisGeNET Detail
Sublethally irradiated NOD/Shi-scidIL2rγ(null) mice transplanted with human umbilical cord blood (Hu... DisGeNET Detail
NA DisGeNET Detail
However, at least half of dominant ataxias (SCAs) are caused by (CAG)n repeat expansions resulting i... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Immunodeficient NOD SCID IL-2R(-/-) mice were immunologically reconstituted by adoptive transfer of ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Mutations in NLRP7 (NOD-like-receptor family, pyrin domain containing 7) are responsible for a type ... DisGeNET Detail
Here we show that Deaf1-Var1 expression correlates with the severity of disease in NOD mice and is r... DisGeNET Detail
Immunodeficient NOD SCID IL-2R(-/-) mice were immunologically reconstituted by adoptive transfer of ... DisGeNET Detail
Notably, CD24+ cells produce tumors following inoculation of as few as 500 cells in immunodeficient ... DisGeNET Detail
These findings were also observed in immunodeficient NOD/SCID mice treated with K562 EVs; BCR/ABL mR... DisGeNET Detail
We generated a severe immunodeficient NOD/Shi-scid-IL-2Rγ(null) (NOG) mouse substrain expressing the... DisGeNET Detail
Human CD34(+) human cord blood cells were transduced with an FV vector encoding a methylguanine meth... DisGeNET Detail
NA DisGeNET Detail
Expression of members of the NOD domain-like receptor family of inflammasome genes was significantly... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Importantly, DLL4 blockade impaired growth of T-ALL cells in NOD/SCID mice and increased leukemia ce... DisGeNET Detail
We previously described that rapid engraftment of patient ALL cells transplanted onto NOD/SCID mice ... DisGeNET Detail
Notably, C1 administration impaired the regeneration of leukemia in secondary serial transplantation... DisGeNET Detail
Inhibition of IL-6 signaling with antibodies or small-molecule Janus kinase inhibitors reversed tole... DisGeNET Detail
Attenuated measles virus controls pediatric acute B-lineage lymphoblastic leukemia in NOD/SCID mice. DisGeNET Detail
Attenuated measles virus controls pediatric acute B-lineage lymphoblastic leukemia in NOD/SCID mice. DisGeNET Detail
NA DisGeNET Detail
Although the in vivo NOD-SCID or NSG xenotransplantation model is currently still the favored assay ... DisGeNET Detail
NA DisGeNET Detail
The administration of actinomycin D, an inhibitor of de novo mRNA synthesis, prevented the abnormali... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
GIMAP5 has a key role in BB-DR rat and NOD mouse lymphopenia. DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
The NOD-like receptor signalling pathway in Helicobacter pylori infection and related gastric cancer... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
We demonstrated that both splenic and peripheral blood (PB) MF CD34(+) cells equally share a defecti... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
In vitro and in vivo assays were carried out to evaluate the effects of NRP1 on malignant phenotypes... DisGeNET Detail
In vivo studies with xenotransplant models in NOD-scid mice showed that OPN expression increases can... DisGeNET Detail
NOD/SCID gamma mouse xenografts demonstrated tumor formation and metastasis. DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Transcriptome analysis of human adipocytes implicates the NOD-like receptor pathway in obesity-induc... DisGeNET Detail
Nucleotide-binding oligomerization domain (NOD) protein, as cytoplasmic receptor of the innate immun... DisGeNET Detail
NA DisGeNET Detail
Expression of members of the NOD domain-like receptor family of inflammasome genes was significantly... DisGeNET Detail
NOD/SCID nude mice experiments showed that ovarian cancer stem cell tumorigenicity was significantly... DisGeNET Detail
In vivo treatment of orthotopic pancreatic tumors in NOD/SCID mice with GSI blocked tumor growth and... DisGeNET Detail
A biopsy of fresh tracheal papilloma was xenografted into a NOD-scid-IL2Rgamma(null) (NSG) mouse. DisGeNET Detail
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Among these genes, we identified that several significant pathways, including the type I diabetes me... DisGeNET Detail
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NOD-like receptor signaling pathway and shigellosis related pathway were the most significant latent... DisGeNET Detail
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Immunodeficient NOD SCID IL-2R(-/-) mice were immunologically reconstituted by adoptive transfer of ... DisGeNET Detail
Additionally, in vivo studies showed that wogonin decreased the number of CML cells and prolonged su... DisGeNET Detail
TG20 cells possess all of the characteristic features of GSCs: the expression of neural stem cell ma... DisGeNET Detail
In vivo, DLL4 is expressed in the spleen and the bone marrow (BM) of NOD/SCID mice bearing T-ALL xen... DisGeNET Detail
NOD/SCID nude mice experiments showed that ovarian cancer stem cell tumorigenicity was significantly... DisGeNET Detail
The human U87MG GBM cell line or patient-derived early passage GBM cells were administered to the st... DisGeNET Detail
The therapeutic efficacy of HuMoSCs was evaluated by using a graft-versus-host disease (GvHD) model ... DisGeNET Detail
NOD/SCID gamma mice produced useful patient-derived xenografts for orthotopic or metastatic models. DisGeNET Detail
Orthotopic xenografts of human CM were established by subconjunctival injection of three different C... DisGeNET Detail
Modified cells maintained their ability to engraft NOD/SCID/IL2rγ(null) mice and to produce cells fr... DisGeNET Detail
Human CD34(+) human cord blood cells were transduced with an FV vector encoding a methylguanine meth... DisGeNET Detail
NOD/SCID gamma mice bearing CEM or Molt4 xenografts were treated with 6-TG and PDX alone or in combi... DisGeNET Detail
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The study suggested CEBPD, FOSB, SFN, KLF5, PTX3, NR4A3, IL-6, and NOD-like receptor pathways were i... DisGeNET Detail
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Here we evaluated the enhanced efficacy of cationic liposome-mediated delivery of FUS1 and human IL ... DisGeNET Detail
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The study suggested CEBPD, FOSB, SFN, KLF5, PTX3, NR4A3, IL-6, and NOD-like receptor pathways were i... DisGeNET Detail
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Some 75% of pre-diabetic NOD/DR4/B7 dTg mice treated with hu DEF-GAD65 chimera remained euglycemic a... DisGeNET Detail
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Activating-mutations in NOD-like receptor (NLR) family, pyrin domain-containing 3 (NLRP3) cause neon... DisGeNET Detail
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Here we evaluated the enhanced efficacy of cationic liposome-mediated delivery of FUS1 and human IL ... DisGeNET Detail
Immunodeficient NOD SCID IL-2R(-/-) mice were immunologically reconstituted by adoptive transfer of ... DisGeNET Detail
The NOD-like receptor signalling pathway in Helicobacter pylori infection and related gastric cancer... DisGeNET Detail
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The antitumor activity was displayed when orally administered to MPM-bearing NOD/SCID mice. DisGeNET Detail
The NOD-like receptor signalling pathway in Helicobacter pylori infection and related gastric cancer... DisGeNET Detail
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Endoplasmic reticulum stress (ER stress)-associated thioredoxin-interacting protein (TXNIP) and NOD-... DisGeNET Detail
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NOD/SCID nude mice experiments showed that ovarian cancer stem cell tumorigenicity was significantly... DisGeNET Detail
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Among these genes, we identified that several significant pathways, including the type I diabetes me... DisGeNET Detail
The role of intracellular innate immune receptors, the NOD-like receptors, and their associated sign... DisGeNET Detail
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NOD-scid-IL2Rγ(null) mice were subcutaneously implanted with PDAC or PDAC(CBL-low) cells on opposite... DisGeNET Detail
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In vivo, DLL4 is expressed in the spleen and the bone marrow (BM) of NOD/SCID mice bearing T-ALL xen... DisGeNET Detail
Attenuated measles virus controls pediatric acute B-lineage lymphoblastic leukemia in NOD/SCID mice. DisGeNET Detail
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Expression of members of the NOD domain-like receptor family of inflammasome genes was significantly... DisGeNET Detail
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Here, the authors discuss the current findings on two spontaneous (nonobese diabetic autoimmune bili... DisGeNET Detail
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Mutations in NLRP7 (NOD-like-receptor family, pyrin domain containing 7) are responsible for a type ... DisGeNET Detail
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We demonstrated that both splenic and peripheral blood (PB) MF CD34(+) cells equally share a defecti... DisGeNET Detail
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Endothelial dysfunction: the role of sterol regulatory element-binding protein-induced NOD-like rece... DisGeNET Detail
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However, at least half of dominant ataxias (SCAs) are caused by (CAG)n repeat expansions resulting i... DisGeNET Detail
Endothelial dysfunction: the role of sterol regulatory element-binding protein-induced NOD-like rece... DisGeNET Detail
The cells engrafted in HLA-A2-transgenic NOD-scid IL2rγ(null) mice and could be detected in the bloo... DisGeNET Detail
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Immunodeficient NOD SCID IL-2R(-/-) mice were immunologically reconstituted by adoptive transfer of ... DisGeNET Detail
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Surgically resected early-stage non-small-cell lung carcinoma (NSCLC) tumors were implanted into non... DisGeNET Detail

Overlapped Transcript Coordinates

Gene Transcript ID Exon Number Chromosome Start Stop Type Amino Mutation Transcript Position Links

Overlapped Transcript

Gene Transcript ID Chromosome Start Stop Links
Gene
-
Genome
hg19
Position
chr12:7,033,626-7,051,484
Variant Type
snv
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