Annotation Detail

Information
Associated Genes
ATN1
Associated Variants
ATN1 MUTATION
ATN1 MUTATION
Associated Disease
severe combined immunodeficiency
Source Database
DisGeNET
Description
TG20 cells possess all of the characteristic features of GSCs: the expression of neural stem cell markers, the generation of intracerebral tumors in NOD-SCID-IL2Rγ (NSG) mice as well as in nude mice, and the ability to sustain serial intracerebral transplantations without expressing telomerase, demonstrating the stability of the ALT phenotype in vivo.
Pubmed
25175359
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
6
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0507596300790167
Drugs