Annotation Detail

Information
Associated Genes
ATN1
Associated Variants
ATN1 MUTATION
ATN1 MUTATION
Associated Disease
Infectious Otitis Media
Source Database
DisGeNET
Description
Expression of members of the NOD domain-like receptor family of inflammasome genes was significantly up-regulated early in NTHi infection of the ME, potentially activating specific downstream regulatory cascades that contribute to the proliferative inflammatory response observed during OM.
Pubmed
24652041
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
3
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs