Annotation Detail
Information
- Associated Genes
- ATN1
- Associated Variants
-
ATN1 MUTATION
ATN1 MUTATION - Associated Disease
- chronic lymphocytic leukemia
- Source Database
- DisGeNET
- Description
- Inhibition of IL-6 signaling with antibodies or small-molecule Janus kinase inhibitors reversed tolerization and increased TLR7-stimulated CLL cell numbers in vitro and in NOD-SCIDγc (null) mice.
- Pubmed
- 26041742
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 6
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00108576748832121
Drugs