Annotation Detail

Information
Associated Genes
ATN1
Associated Variants
ATN1 MUTATION
ATN1 MUTATION
Associated Disease
Myeloid Leukemia, Chronic
Source Database
DisGeNET
Description
The administration of actinomycin D, an inhibitor of de novo mRNA synthesis, prevented the abnormalities caused by K562 EVs in NOD/SCID mice related to CML, including neutrophilia and bone marrow hyperplasia.
Pubmed
25133686
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
6
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00108576748832121
Drugs