chr15:39581079:> Detail (hg38)
Information
Genome
| Assembly | Position |
|---|---|
| hg19 | chr15:39,873,280-39,891,667 |
| hg38 | chr15:39,581,079-39,599,466 |
HGVS
| Type | Transcript | Protein |
|---|---|---|
Summary
MGeND
| Clinical significance | |
| Variant entry | |
| GWAS entry | |
| Disease area statistics | Show details |
Frequency
[No Data.]
Prediction
[No Data.]
ClinVar
| Clinical Significance | |
| Review star | [No Data.] |
| Show details | |
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
| Score | Disease name | Description | Source | Pubmed | Links |
|---|---|---|---|---|---|
| 0.006 | squamous cell carcinoma | NA | BeFree,LHGDN | Detail | |
| <0.001 | Carcinoma, Transitional Cell | NA | BeFree | Detail | |
| <0.001 | Cardiovascular Diseases | NA | BeFree | Detail | |
| <0.001 | Malignant tumor of cervix | NA | BeFree | Detail | |
| 0.002 | chorioamnionitis | NA | GAD | Detail | |
| 0.002 | colorectal carcinoma | NA | BeFree | Detail | |
| 0.005 | Colorectal Neoplasms | NA | LHGDN | Detail | |
| <0.001 | Hepatic Fibrosis, Congenital | NA | BeFree | Detail | |
| 0.004 | Coronary Arteriosclerosis | NA | BeFree,GAD | Detail | |
| 0.001 | Coronary heart disease | NA | BeFree | Detail | |
| <0.001 | Crohn Disease | NA | BeFree | Detail | |
| <0.001 | Presenile dementia | NA | BeFree | Detail | |
| <0.001 | dermatitis | NA | BeFree | Detail | |
| <0.001 | scleroderma | NA | BeFree | Detail | |
| <0.001 | Diabetes | THBS1 may act as a critical circulating factor that couples obesity with metabol... | BeFree | 26298466 | Detail |
| <0.001 | diabetes mellitus | THBS1 may act as a critical circulating factor that couples obesity with metabol... | BeFree | 26298466 | Detail |
| 0.080 | Diabetes Mellitus, Experimental | NA | RGD | Detail | |
| <0.001 | Diabetic Angiopathies | NA | BeFree | Detail | |
| 0.006 | Diabetic Nephropathy | NA | BeFree,LHGDN | Detail | |
| 0.200 | diabetic retinopathy | NA | CTD_human,RGD | Detail | |
| <0.001 | Dry Eye Syndromes | NA | BeFree | Detail | |
| 0.001 | endometriosis | NA | BeFree | Detail | |
| 0.002 | Fetal Membranes, Premature Rupture | NA | GAD | Detail | |
| 0.003 | Fever | NA | LHGDN | Detail | |
| 0.120 | Fibrosis | NA | CTD_human | Detail | |
| <0.001 | ganglioneuroma | NA | BeFree | Detail | |
| <0.001 | gastroesophageal reflux disease | NA | BeFree | Detail | |
| <0.001 | glaucoma | NA | BeFree | Detail | |
| 0.002 | glioblastoma | Thrombospondin-1 (TSP-1) and E-cadherin were up-regulated in radixin- suppressed... | BeFree | 25520109 | Detail |
| 0.005 | Glioma | EPB41L3, TSP-1 and RASSF2 as new clinically relevant prognostic biomarkers in di... | BeFree,LHGDN | 25621889 | Detail |
| 0.080 | Heart Diseases | NA | BeFree,RGD | Detail | |
| <0.001 | Heart failure | NA | BeFree | Detail | |
| <0.001 | congestive heart failure | NA | BeFree | Detail | |
| <0.001 | Helminthiasis | NA | BeFree | Detail | |
| <0.001 | hemangioma | NA | BeFree | Detail | |
| <0.001 | Hemangiosarcoma | NA | BeFree | Detail | |
| 0.003 | Hemorrhagic Fever with Renal Syndrome | NA | LHGDN | Detail | |
| 0.001 | HIV Infections | NA | BeFree | Detail | |
| 0.002 | HTLV-I Infections | NA | BeFree | Detail | |
| <0.001 | hyperglycemia | ANCOVA demonstrated that the THBS1 level is associated with abdominal obesity (P... | BeFree | 26298466 | Detail |
| <0.001 | Hypertensive disease | ANCOVA demonstrated that the THBS1 level is associated with abdominal obesity (P... | BeFree | 26298466 | Detail |
| <0.001 | pulmonary hypertension | NA | BeFree | Detail | |
| <0.001 | Immunologic Deficiency Syndromes | NA | BeFree | Detail | |
| <0.001 | Mammary Ductal Carcinoma | NA | BeFree | Detail | |
| 0.011 | Inflammation | NA | LHGDN | Detail | |
| 0.004 | ischemia | NA | BeFree,LHGDN | Detail | |
| 0.003 | keratoacanthoma | NA | LHGDN | Detail | |
| <0.001 | keratoconjunctivitis | NA | BeFree | Detail | |
| 0.002 | Premature Obstetric Labor | NA | GAD | Detail | |
| 0.003 | Fibroid Tumor | NA | BeFree,LHGDN | Detail | |
| <0.001 | leukemia | NA | BeFree | Detail | |
| <0.001 | chronic lymphocytic leukemia | NA | BeFree | Detail | |
| <0.001 | acute promyelocytic leukemia | NA | BeFree | Detail | |
| 0.006 | Leukemia, T-Cell | NA | BeFree | Detail | |
| 0.013 | Adult T-Cell Lymphoma/Leukemia | Human T-cell lymphotropic virus type 1 (HTLV-1) is mainly associated with two di... | BeFree | 24863974 | Detail |
| <0.001 | Lichen Sclerosus et Atrophicus | NA | BeFree | Detail | |
| 0.122 | liver cirrhosis | NA | CTD_human,GAD | Detail | |
| <0.001 | Liver neoplasms | NA | BeFree | Detail | |
| 0.003 | Lung Neoplasms | NA | BeFree,LHGDN | Detail | |
| <0.001 | lymphoma | NA | BeFree | Detail | |
| 0.003 | Malignant neoplasm of stomach | The relationship of CD133, histone deacetylase 1 and thrombospondin-1 in gastric... | BeFree | 25862862 | Detail |
| 0.080 | Mammary Neoplasms, Experimental | NA | RGD | Detail | |
| <0.001 | medulloblastoma | NA | BeFree | Detail | |
| 0.007 | melanoma | We show that miRNAs of the miR-17-92 cluster (miR-20a2, miR-92a1, miR-17 and miR... | BeFree,LHGDN | 24462553 | Detail |
| 0.007 | melanoma | Thrombospondin 1 promotes an aggressive phenotype through epithelial-to-mesenchy... | BeFree,LHGDN | 25051363 | Detail |
| <0.001 | meningioma | NA | BeFree | Detail | |
| <0.001 | multiple myeloma | NA | BeFree | Detail | |
| <0.001 | multiple sclerosis | NA | BeFree | Detail | |
| <0.001 | myopathy | NA | BeFree | Detail | |
| <0.001 | Mycoses | NA | BeFree | Detail | |
| 0.094 | myocardial infarction | NA | BeFree,GAD,LHGDN,RGD | Detail | |
| 0.080 | Myocardial Reperfusion Injury | NA | RGD | Detail | |
| 0.012 | Neoplasm Metastasis | Upregulation of anti-angiogenic factor Thrombospondin-1 (TSP-1) accords for ther... | BeFree,LHGDN | 25552929 | Detail |
| 0.120 | Nephritis, Interstitial | NA | CTD_human | Detail | |
| 0.002 | nervous system disorder | NA | BeFree | Detail | |
| <0.001 | neuroblastoma | NA | BeFree | Detail | |
| <0.001 | Nodule | NA | BeFree | Detail | |
| 0.002 | obesity | Taken together, these studies provide novel evidence that the interaction of TSP... | BeFree | 25835637 | Detail |
| 0.002 | obesity | Thrombospondin 1 as a novel biological marker of obesity and metabolic syndrome. | BeFree | 26298466 | Detail |
| <0.001 | oligodendroglioma | This observation was confirmed after adjusting the results for age and tumor gra... | BeFree | 25621889 | Detail |
| <0.001 | Degenerative polyarthritis | NA | BeFree | Detail | |
| 0.004 | osteosarcoma | NA | BeFree,LHGDN | Detail | |
| 0.002 | ovarian carcinoma | NA | BeFree | Detail | |
| <0.001 | Ovarian Diseases | NA | BeFree | Detail | |
| <0.001 | Pancreatic Neoplasm | NA | BeFree | Detail | |
| <0.001 | papilloma | NA | BeFree | Detail | |
| 0.014 | tropical spastic paraparesis | NA | BeFree | Detail | |
| <0.001 | Parasitic Diseases | NA | BeFree | Detail | |
| 0.003 | Penile Neoplasms | NA | LHGDN | Detail | |
| <0.001 | pneumonia | NA | BeFree | Detail | |
| <0.001 | polyps | NA | BeFree | Detail | |
| 0.002 | pre-eclampsia | NA | GAD | Detail | |
| <0.001 | Precancerous Conditions | NA | BeFree | Detail | |
| 0.081 | Prostatic Neoplasms | NA | BeFree,RGD | Detail | |
| <0.001 | Purpura, Thrombotic Thrombocytopenic | NA | BeFree | Detail | |
| 0.120 | Reperfusion Injury | NA | CTD_human | Detail | |
| 0.120 | schizophrenia | NA | BeFree,CTD_human | Detail | |
| <0.001 | systemic scleroderma | NA | BeFree | Detail | |
| <0.001 | Paraparesis, Spastic | NA | BeFree | Detail | |
| 0.001 | Spinal Cord Diseases | NA | BeFree | Detail | |
| 0.003 | Stomach Neoplasms | NA | BeFree,LHGDN | Detail | |
| 0.003 | Cerebrovascular accident | NA | BeFree,GAD | Detail | |
| 0.003 | synovitis | NA | LHGDN | Detail | |
| <0.001 | Giant Cell Arteritis | NA | BeFree | Detail | |
| 0.005 | Thyroid Neoplasm | NA | LHGDN | Detail | |
| <0.001 | Vascular Diseases | NA | BeFree | Detail | |
| <0.001 | Virus Diseases | NA | BeFree | Detail | |
| <0.001 | Lymphoma, T-Cell, Cutaneous | NA | BeFree | Detail | |
| <0.001 | Peripheral Vascular Diseases | NA | BeFree | Detail | |
| 0.007 | colorectal cancer | Ten non-synonymous single nucleotide polymorphisms (nsSNPs), which were recently... | BeFree | 18619730 | Detail |
| 0.002 | colorectal carcinoma | Ten non-synonymous single nucleotide polymorphisms (nsSNPs), which were recently... | BeFree | 18619730 | Detail |
| <0.001 | polymyositis | NA | BeFree | Detail | |
| <0.001 | Chronic gastritis | NA | BeFree | Detail | |
| <0.001 | Pancreatitis, Chronic | The novel biomarker panel obtained by combining α-1-antichymotrypsin (AACT), Thr... | BeFree | 25393578 | Detail |
| 0.002 | Premature Birth | NA | GAD | Detail | |
| <0.001 | renal fibrosis | NA | BeFree | Detail | |
| <0.001 | Adenocarcinoma of lung (disorder) | NA | BeFree | Detail | |
| <0.001 | Idiopathic pulmonary hypertension | NA | BeFree | Detail | |
| <0.001 | Systemic candidiasis | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of penis | NA | BeFree | Detail | |
| 0.001 | Secondary malignant neoplasm of lung | NA | BeFree | Detail | |
| <0.001 | Hypertrophy of kidney | NA | BeFree | Detail | |
| 0.004 | Tumor Progression | NA | BeFree | Detail | |
| <0.001 | Follicular thyroid carcinoma | NA | BeFree | Detail | |
| <0.001 | Cervical Intraepithelial Neoplasia | NA | BeFree | Detail | |
| <0.001 | uveal melanoma | NA | BeFree | Detail | |
| 0.002 | pancreatic carcinoma | The novel biomarker panel obtained by combining α-1-antichymotrypsin (AACT), Thr... | BeFree | 25393578 | Detail |
| 0.003 | Inclusion Body Myositis (disorder) | NA | BeFree,LHGDN | Detail | |
| <0.001 | Squamous cell carcinoma of penis | NA | BeFree | Detail | |
| <0.001 | Papillary thyroid carcinoma | NA | BeFree | Detail | |
| <0.001 | Fibrosis, Liver | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of lung | NA | BeFree | Detail | |
| <0.001 | Carcinoma, Lewis Lung | NA | BeFree | Detail | |
| <0.001 | Dermatomyositis, Childhood Type | NA | BeFree | Detail | |
| <0.001 | Endometrioma | NA | BeFree | Detail | |
| <0.001 | Impaired glucose tolerance | NA | BeFree | Detail | |
| <0.001 | Malignant Childhood Neoplasm | NA | BeFree | Detail | |
| <0.001 | Metastatic melanoma | In addition, we found aberrant THBS1 protein expression in metastatic melanoma t... | BeFree | 25051363 | Detail |
| <0.001 | T-cell adult acute lymphoblastic leukemia | NA | BeFree | Detail | |
| <0.001 | Squamous cell carcinoma of esophagus | NA | BeFree | Detail | |
| <0.001 | cervical squamous cell carcinoma | NA | BeFree | Detail | |
| <0.001 | Solid tumour | NA | BeFree | Detail | |
| <0.001 | Adenocarcinoma of pancreas | NA | BeFree | Detail | |
| <0.001 | cervix carcinoma | NA | BeFree | Detail | |
| <0.001 | Obesity, Abdominal | ANCOVA demonstrated that the THBS1 level is associated with abdominal obesity (P... | BeFree | 26298466 | Detail |
| <0.001 | Dryness of eye | NA | BeFree | Detail | |
| <0.001 | Restenosis | NA | BeFree | Detail | |
| <0.001 | High-Grade Squamous Intraepithelial Lesions | NA | BeFree | Detail | |
| <0.001 | Clear cell sarcoma of kidney | NA | BeFree | Detail | |
| <0.001 | anaplastic oligodendroglioma | This observation was confirmed after adjusting the results for age and tumor gra... | BeFree | 25621889 | Detail |
| 0.003 | Epiretinal Membrane | NA | LHGDN | Detail | |
| <0.001 | Corticosteroid-induced glaucoma | NA | BeFree | Detail | |
| 0.002 | Malignant neoplasm of pancreas | The novel biomarker panel obtained by combining α-1-antichymotrypsin (AACT), Thr... | BeFree | 25393578 | Detail |
| <0.001 | Human T-cell lymphotrophic virus, type I [HTLV-I] | NA | BeFree | Detail | |
| 0.004 | Malignant neoplasm of prostate | NA | BeFree,GAD | Detail | |
| <0.001 | endometrial carcinoma | NA | BeFree | Detail | |
| <0.001 | Secondary malignant neoplasm of liver | The expression of six genes was significantly different in primary tumors compar... | BeFree | 25301403 | Detail |
| 0.003 | dementia | NA | BeFree,LHGDN | Detail | |
| <0.001 | Overweight | The relationships between serum THBS1 level and obesity/diabetes traits as well ... | BeFree | 26298466 | Detail |
| <0.001 | Recurrent tumor | NA | BeFree | Detail | |
| <0.001 | Metabolic syndrome X | Thrombospondin 1 as a novel biological marker of obesity and metabolic syndrome. | BeFree | 26298466 | Detail |
| 0.002 | Thyroid carcinoma | NA | BeFree | Detail | |
| <0.001 | Alveolitis | NA | BeFree | Detail | |
| 0.002 | Brain hemorrhage | NA | GAD | Detail | |
| <0.001 | Malignant glioma | NA | BeFree | Detail | |
| <0.001 | Cutaneous hypersensitivity | NA | BeFree | Detail | |
| <0.001 | Osteosarcoma of bone | NA | BeFree | Detail | |
| <0.001 | Aqueous Humor Disorders | NA | BeFree | Detail | |
| 0.003 | Carcinogenesis | NA | BeFree | Detail | |
| 0.001 | prostate carcinoma | NA | BeFree | Detail | |
| 0.002 | hepatopulmonary syndrome | NA | GAD | Detail | |
| <0.001 | Epithelial ovarian cancer | Combined therapy with thrombospondin-1 type I repeats (3TSR) and chemotherapy in... | BeFree | 25395453 | Detail |
| <0.001 | Progressive Neoplastic Disease | NA | BeFree | Detail | |
| <0.001 | Sentinel node (disorder) | NA | BeFree | Detail | |
| 0.006 | breast carcinoma | Decrease of let-7f in low-dose metronomic Paclitaxel chemotherapy contributed to... | BeFree | 25552929 | Detail |
| <0.001 | inflammatory joint disease | NA | BeFree | Detail | |
| <0.001 | Carcinoma of lung | NA | BeFree | Detail | |
| 0.001 | Secondary malignant neoplasm of lymph node | NA | BeFree | Detail | |
| 0.002 | colon carcinoma | NA | BeFree | Detail | |
| 0.003 | stomach carcinoma | The relationship of CD133, histone deacetylase 1 and thrombospondin-1 in gastric... | BeFree | 25862862 | Detail |
| <0.001 | Carcinoma of bladder | NA | BeFree | Detail | |
| <0.001 | skin carcinoma | NA | BeFree | Detail | |
| <0.001 | Central neuroblastoma | NA | BeFree | Detail | |
| <0.001 | Dissecting aneurysm of the thoracic aorta | NA | BeFree | Detail | |
| <0.001 | Parasitic infection | NA | BeFree | Detail | |
| <0.001 | Well Differentiated Oligodendroglioma | This observation was confirmed after adjusting the results for age and tumor gra... | BeFree | 25621889 | Detail |
| <0.001 | Inclusion Body Myopathy, Sporadic | NA | BeFree | Detail | |
| <0.001 | malignant pleural mesothelioma | NA | BeFree | Detail | |
| <0.001 | thrombocytosis | NA | BeFree | Detail | |
| <0.001 | Helicobacter pylori infection | NA | BeFree | Detail | |
| <0.001 | penis carcinoma | NA | BeFree | Detail | |
| <0.001 | Invasive breast carcinoma | NA | BeFree | Detail | |
| <0.001 | Carcinoma, Pancreatic Ductal | NA | BeFree | Detail | |
| <0.001 | Arteriovenous Malformations, Cerebral | NA | BeFree | Detail | |
| <0.001 | Ischemic stroke | These results demonstrate that miR-487b regulates angiogenesis by directly targe... | BeFree | 25660232 | Detail |
| 0.002 | Acute coronary syndrome | NA | GAD | Detail | |
| <0.001 | Colorectal cancer metastatic | NA | BeFree | Detail | |
| <0.001 | Vascular occlusion | NA | BeFree | Detail | |
| <0.001 | Invasive Ductal Breast Carcinoma | NA | BeFree | Detail | |
| 0.002 | Malignant neoplasm of ovary | NA | BeFree | Detail | |
| <0.001 | Infective dermatitis | NA | BeFree | Detail | |
| 0.003 | sarcoma | NA | LHGDN | Detail | |
| <0.001 | Corneal allograft rejection | NA | BeFree | Detail | |
| 0.001 | Inflammatory disorder | NA | BeFree | Detail | |
| <0.001 | Primary Effusion Lymphoma | NA | BeFree | Detail | |
| <0.001 | Radial scar | NA | BeFree | Detail | |
| <0.001 | Low Grade Squamous Intraepithelial Neoplasia | NA | BeFree | Detail | |
| <0.001 | Liver regeneration disorder | Effect of LSKL peptide on thrombospondin 1-mediated transforming growth factor β... | BeFree | 25866938 | Detail |
| <0.001 | congenital mesoblastic nephroma | NA | BeFree | Detail | |
| <0.001 | gastric cardia adenocarcinoma | NA | BeFree | Detail | |
| <0.001 | Infiltrating Cervical Carcinoma | NA | BeFree | Detail | |
| <0.001 | Oligodendroglial Neoplasm | Our objectives were to analyze the presence of the hypermethylation of EPB41L3, ... | BeFree | 25621889 | Detail |
| <0.001 | pancreatic ductal adenocarcinoma | Chromosome maintenance region 1 (CRM1) also called Exportin 1 (Xpo1), a protein ... | BeFree | 24899509 | Detail |
| <0.001 | renal carcinoma | NA | BeFree | Detail | |
| 0.124 | Mammary Neoplasms | Here, we hypothesize that miRNAs are involved in TSP-1 overexpression in paclita... | BeFree,CTD_human,LHGDN | 25552929 | Detail |
| <0.001 | Angiogenic Switch | NA | BeFree | Detail | |
| <0.001 | Desmoplastic | NA | BeFree | Detail | |
| 0.002 | Human T-cell lymphotropic virus 1 infection | NA | BeFree | Detail | |
| <0.001 | Cancer Cell Growth | NA | BeFree | Detail | |
| <0.001 | Malignant Conversion | NA | BeFree | Detail | |
| <0.001 | Neuropathogenesis | NA | BeFree | Detail | |
| 0.003 | Tumor Angiogenesis | They can modulate pro-angiogenic signals induced by vascular endothelial growth ... | BeFree | 26144623 | Detail |
| 0.007 | colorectal cancer | NA | BeFree,GAD | Detail | |
| 0.080 | Sjogren's syndrome | NA | MGD | Detail | |
| <0.001 | Ocular surface disease | NA | BeFree | Detail | |
| <0.001 | Glioblastoma multiforme | NA | BeFree | Detail | |
| <0.001 | Benign Prostatic Hyperplasia | NA | BeFree | Detail | |
| <0.001 | Peripheral Arterial Diseases | NA | BeFree | Detail | |
| <0.001 | Direct Contact Transmission Infection | NA | BeFree | Detail | |
| <0.001 | Malformations of Cortical Development, Group II | NA | BeFree | Detail | |
| <0.001 | Laryngeal Atresia, Encephalocele, and Limb Deformities | NA | BeFree | Detail | |
| <0.001 | stiff skin syndrome | NA | BeFree | Detail | |
| <0.001 | uterine corpus cancer | NA | BeFree | Detail | |
| 0.004 | coronary artery disease | NA | BeFree,LHGDN | Detail | |
| <0.001 | Urothelial Carcinoma | NA | BeFree | Detail | |
| 0.004 | liver carcinoma | NA | BeFree,LHGDN | Detail | |
| <0.001 | Thrombotic thrombocytopenic purpura, acquired | NA | BeFree | Detail | |
| <0.001 | Promyelocytic leukemia | NA | BeFree | Detail | |
| 0.002 | Infection of amniotic sac and membranes, unspecified, unspecified trimester, not applicable or unspecified | NA | GAD | Detail | |
| <0.001 | Juvenile dermatomyositis | NA | BeFree | Detail | |
| <0.001 | Nasopharyngeal carcinoma | Compared with vector-alone control cells, BLU stable transfectants, derived from... | BeFree | 25347745 | Detail |
| <0.001 | Obesity, Visceral | In this study, we aimed to determine the clinical significance of THBS1 as a nov... | BeFree | 26298466 | Detail |
| 0.080 | Cerebral Hemorrhage | NA | RGD | Detail | |
| <0.001 | Pulmonary arterial hypertension | NA | BeFree | Detail | |
| 0.002 | Stroke, Lacunar | NA | GAD | Detail | |
| <0.001 | Ischemic Cerebrovascular Accident | These results demonstrate that miR-487b regulates angiogenesis by directly targe... | BeFree | 25660232 | Detail |
| 0.120 | Juvenile arthritis | NA | CTD_human | Detail | |
| <0.001 | Progressive cGVHD | NA | BeFree | Detail | |
| <0.001 | Fibromyxosarcoma | NA | BeFree | Detail | |
| <0.001 | Pulmonary hypertension, primary, 1, with hereditary hemorrhagic telangiectasia | NA | BeFree | Detail | |
| <0.001 | acquired immunodeficiency syndrome | NA | BeFree | Detail | |
| 0.004 | adenocarcinoma | NA | BeFree,LHGDN | Detail | |
| 0.004 | adenoma | NA | BeFree,LHGDN | Detail | |
| 0.003 | Anoxia | NA | LHGDN | Detail | |
| 0.001 | arteriosclerosis | NA | BeFree | Detail | |
| <0.001 | Congenital arteriovenous malformation | NA | BeFree | Detail | |
| <0.001 | arthritis | NA | BeFree | Detail | |
| 0.004 | rheumatoid arthritis | NA | BeFree,LHGDN | Detail | |
| <0.001 | Astrocytoma | Our objectives were to analyze the presence of the hypermethylation of EPB41L3, ... | BeFree | 25621889 | Detail |
| 0.003 | atherosclerosis | NA | BeFree,GAD | Detail | |
| <0.001 | autistic disorder | Common and rare variants of the THBS1 gene associated with the risk for autism. | BeFree | 25304225 | Detail |
| <0.001 | Malignant neoplasm of urinary bladder | NA | BeFree | Detail | |
| 0.001 | Bone Marrow Diseases | NA | BeFree | Detail | |
| 0.006 | Malignant neoplasm of breast | Decrease of let-7f in low-dose metronomic Paclitaxel chemotherapy contributed to... | BeFree | 25552929 | Detail |
| <0.001 | Carcinoid Tumor | NA | BeFree | Detail | |
| 0.002 | Malignant tumor of colon | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of endometrium | NA | BeFree | Detail | |
| 0.001 | Malignant neoplasm of thyroid | NA | BeFree | Detail | |
| <0.001 | Non-small cell lung carcinoma | NA | BeFree | Detail | |
| 0.004 | renal cell carcinoma | NA | BeFree,LHGDN | Detail |
Annotation
Annotations
| Descrption | Source | Links |
|---|---|---|
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| THBS1 may act as a critical circulating factor that couples obesity with metabolic syndrome and diab... | DisGeNET | Detail |
| THBS1 may act as a critical circulating factor that couples obesity with metabolic syndrome and diab... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Thrombospondin-1 (TSP-1) and E-cadherin were up-regulated in radixin- suppressed glioblastoma U251 c... | DisGeNET | Detail |
| EPB41L3, TSP-1 and RASSF2 as new clinically relevant prognostic biomarkers in diffuse gliomas. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| ANCOVA demonstrated that the THBS1 level is associated with abdominal obesity (P<0.001), hyperglycem... | DisGeNET | Detail |
| ANCOVA demonstrated that the THBS1 level is associated with abdominal obesity (P<0.001), hyperglycem... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Human T-cell lymphotropic virus type 1 (HTLV-1) is mainly associated with two diseases: tropical spa... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
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| The relationship of CD133, histone deacetylase 1 and thrombospondin-1 in gastric cancer. | DisGeNET | Detail |
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| We show that miRNAs of the miR-17-92 cluster (miR-20a2, miR-92a1, miR-17 and miR-18a), miR-126, miR-... | DisGeNET | Detail |
| Thrombospondin 1 promotes an aggressive phenotype through epithelial-to-mesenchymal transition in hu... | DisGeNET | Detail |
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| Upregulation of anti-angiogenic factor Thrombospondin-1 (TSP-1) accords for therapeutic potency of L... | DisGeNET | Detail |
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| Taken together, these studies provide novel evidence that the interaction of TSP1 with its receptor ... | DisGeNET | Detail |
| Thrombospondin 1 as a novel biological marker of obesity and metabolic syndrome. | DisGeNET | Detail |
| This observation was confirmed after adjusting the results for age and tumor grade, the role of TSP-... | DisGeNET | Detail |
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| Ten non-synonymous single nucleotide polymorphisms (nsSNPs), which were recently associated with col... | DisGeNET | Detail |
| Ten non-synonymous single nucleotide polymorphisms (nsSNPs), which were recently associated with col... | DisGeNET | Detail |
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| The novel biomarker panel obtained by combining α-1-antichymotrypsin (AACT), Thrombospondin-1 (THBS1... | DisGeNET | Detail |
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| The novel biomarker panel obtained by combining α-1-antichymotrypsin (AACT), Thrombospondin-1 (THBS1... | DisGeNET | Detail |
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| In addition, we found aberrant THBS1 protein expression in metastatic melanoma tumor biopsies. | DisGeNET | Detail |
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| ANCOVA demonstrated that the THBS1 level is associated with abdominal obesity (P<0.001), hyperglycem... | DisGeNET | Detail |
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| This observation was confirmed after adjusting the results for age and tumor grade, the role of TSP-... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
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| The novel biomarker panel obtained by combining α-1-antichymotrypsin (AACT), Thrombospondin-1 (THBS1... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
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| The expression of six genes was significantly different in primary tumors compared with their matche... | DisGeNET | Detail |
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| The relationships between serum THBS1 level and obesity/diabetes traits as well as the diagnostic co... | DisGeNET | Detail |
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| Thrombospondin 1 as a novel biological marker of obesity and metabolic syndrome. | DisGeNET | Detail |
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| Combined therapy with thrombospondin-1 type I repeats (3TSR) and chemotherapy induces regression and... | DisGeNET | Detail |
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| Decrease of let-7f in low-dose metronomic Paclitaxel chemotherapy contributed to upregulation of thr... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
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| The relationship of CD133, histone deacetylase 1 and thrombospondin-1 in gastric cancer. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
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| This observation was confirmed after adjusting the results for age and tumor grade, the role of TSP-... | DisGeNET | Detail |
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| These results demonstrate that miR-487b regulates angiogenesis by directly targeting THBS1 in HUVECs... | DisGeNET | Detail |
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| Effect of LSKL peptide on thrombospondin 1-mediated transforming growth factor β signal activation a... | DisGeNET | Detail |
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| Our objectives were to analyze the presence of the hypermethylation of EPB41L3, RASSF2 and TSP-1 gen... | DisGeNET | Detail |
| Chromosome maintenance region 1 (CRM1) also called Exportin 1 (Xpo1), a protein found elevated in pa... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Here, we hypothesize that miRNAs are involved in TSP-1 overexpression in paclitaxel LDM therapy of b... | DisGeNET | Detail |
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| They can modulate pro-angiogenic signals induced by vascular endothelial growth factor (VEGF) and an... | DisGeNET | Detail |
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| Compared with vector-alone control cells, BLU stable transfectants, derived from poorly-differentiat... | DisGeNET | Detail |
| In this study, we aimed to determine the clinical significance of THBS1 as a novel biological marker... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
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| These results demonstrate that miR-487b regulates angiogenesis by directly targeting THBS1 in HUVECs... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
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| Our objectives were to analyze the presence of the hypermethylation of EPB41L3, RASSF2 and TSP-1 gen... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Common and rare variants of the THBS1 gene associated with the risk for autism. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Decrease of let-7f in low-dose metronomic Paclitaxel chemotherapy contributed to upregulation of thr... | DisGeNET | Detail |
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Overlapped Transcript Coordinates
| Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
|---|
Overlapped Transcript
| Gene | Transcript ID | Chromosome | Start | Stop | Links |
|---|
- Gene
- -
- dbSNP
- rs386559608 dbSNP
- Genome
- hg38
- Position
- chr15:39,581,079-39,599,466
- Variant Type
- snv
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