Annotation Detail
Information
- Associated Genes
- THBS1
- Associated Variants
-
THBS1 MUTATION
THBS1 MUTATION - Associated Disease
- Nasopharyngeal carcinoma
- Source Database
- DisGeNET
- Description
- Compared with vector-alone control cells, BLU stable transfectants, derived from poorly-differentiated NPC HONE1 cells, suppress VEGF165, VEGF189 and TSP1 expression at both the RNA and protein levels, and significantly reduce the secreted VEGF protein in these cells, reflecting an unknown regulatory mechanism mediated by the BLU gene in NPC.
- Pubmed
- 25347745
- Section of the abstract supporting the evidence
- ALL_TEXT_2/3
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 6
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00081432561624091
Drugs